公开(公告)号：US20240108277A1

公开(公告)日：2024-04-04

申请号：US18263558

申请日：2022-01-31

申请人： The General Hospital Corporation

发明人： Guillermo Tearney ,  David Odeke Otuya ,  Hamid Farrokhi ,  Serena Qinyun Z Shi ,  Sarah Lynn Silva ,  Jing Dong

IPC分类号： A61B5/00 ,  A61B5/06 ,  A61B5/24 ,  A61B5/262 ,  A61B5/265 ,  A61B5/301

CPC分类号： A61B5/4255 ,  A61B5/065 ,  A61B5/2415 ,  A61B5/262 ,  A61B5/265 ,  A61B5/301 ,  A61B5/6847 ,  A61B90/08 ,  A61B2560/0468 ,  A61B2562/14

摘要： A system for determining intestinal potential difference. The system includes a measurement probe including a measurement tube having a measurement lumen which houses a measurement electrode therein, a measurement fluid delivery system in fluid communication with the measurement lumen, the measurement fluid delivery system being configured to deliver an electrically-conductive fluid into the measurement lumen such that the electrically-conductive fluid is electrically coupled to the measurement electrode, and the measurement lumen including an outlet at a distal end thereof through which the electrically-conductive fluid exits the measurement lumen and contacts an intestinal tissue of a subject to provide electrical coupling between the measurement electrode and the intestinal tissue; a controller coupled to the measurement electrode configured to measure a potential difference between tire measurement electrode and a reference electrode electrically coupled to the subject.