公开(公告)号：US11839728B2

公开(公告)日：2023-12-12

申请号：US16607493

申请日：2018-04-24

Applicant: The General Hospital Corporation

Inventor： Guillermo J. Tearney ,  Jing Dong ,  David Odeke Otuya ,  Yogesh Verma ,  Hamid Farrokhi

IPC: A61M25/10 ,  A61B1/07 ,  A61B1/233 ,  A61B5/00 ,  A61B10/04 ,  A61L29/08

CPC classification number: A61M25/10184 ,  A61B1/07 ,  A61B1/233 ,  A61B5/0066 ,  A61B5/0084 ,  A61B5/42 ,  A61B10/04 ,  A61L29/08 ,  A61M2025/1043

Abstract: A catheter including an elongated tube having a channel; an inflatable chamber coupled to the elongated tube and in fluid communication with the channel; and a high-density liquid delivery system in fluid communication with the channel, the high-density liquid delivery system delivering a high-density liquid to the inflatable chamber via the channel to cause the inflatable chamber to expand.

公开(公告)号：US11147503B2

公开(公告)日：2021-10-19

申请号：US15882557

申请日：2018-01-29

Applicant: The General Hospital Corporation

Inventor： Guillermo J. Tearney ,  Rohith K. Reddy ,  Michalina J. Gora ,  Kengyeh K. Chu ,  Matthew Beatty ,  Jing Dong ,  Emilie Beaulieu-Ouellet

IPC: A61B5/00 ,  A61B1/06 ,  A61B1/00 ,  A61B1/04

Abstract: Systems and methods for a tethered optical imaging probe configured to be integrated into an optical system for medical diagnosis are provided. In one configuration, the present disclosure provides a tethered optical imaging probe including a motor arranged within a swallowable capsule. A rotational speed of the motor is actively controlled by a feedback signal.

公开(公告)号：US20180160965A1

公开(公告)日：2018-06-14

申请号：US15882557

申请日：2018-01-29

Applicant: The General Hospital Corporation

Inventor： Guillermo J. Tearney ,  Rohith K. Reddy ,  Michalina J. Gora ,  Kengyeh K. Chu ,  Matthew Beatty ,  Jing Dong ,  Emilie Beaulieu-Ouellet

IPC: A61B5/00 ,  A61B1/06

CPC classification number: A61B5/4255 ,  A61B1/00006 ,  A61B1/00096 ,  A61B1/00179 ,  A61B1/00183 ,  A61B1/041 ,  A61B1/0615 ,  A61B1/0653 ,  A61B1/0661 ,  A61B5/0071 ,  A61B5/0084 ,  A61B5/6861

Abstract: Systems and methods for a tethered optical imaging probe configured to be integrated into an optical system for medical diagnosis are provided. In one configuration, the present disclosure provides a tethered optical imaging probe including a motor arranged within a swallowable capsule. A rotational speed of the motor is actively controlled by a feedback signal.

公开(公告)号：US20210000521A1

公开(公告)日：2021-01-07

申请号：US16976427

申请日：2019-02-01

Applicant: THE GENERAL HOSPITAL CORPORATION

Inventor： Guillermo J. Tearney ,  David Otuya ,  Yogesh Verma ,  Jing Dong ,  Hamid Ferrokhi

IPC: A61B18/02 ,  A61B90/00 ,  A61B10/04 ,  A61B18/00

Abstract: In some embodiments, devices, systems, and methods for cryogenic biopsy sampling are provided. In some embodiments, a device for cryogenic biopsy sampling is provided, the device including: a dual lumen tube; an elongated probe tip coupled to the distal end of the dual lumen tube, with a first lumen extending into a hollow portion in the tip and a second lumen in fluid communication with the hollow portion; a first port in fluid communication with the first lumen; a second port in fluid communication with the second lumen, wherein the first lumen, the elongated probe element, and the second lumen provide a closed pathway through which a substance introduced through the first port can flow through the first lumen into the elongated probe element, and out of the elongated probe element through the second lumen to the second port.

公开(公告)号：US20240108277A1

公开(公告)日：2024-04-04

申请号：US18263558

申请日：2022-01-31

Applicant: The General Hospital Corporation

Inventor： Guillermo Tearney ,  David Odeke Otuya ,  Hamid Farrokhi ,  Serena Qinyun Z Shi ,  Sarah Lynn Silva ,  Jing Dong

IPC: A61B5/00 ,  A61B5/06 ,  A61B5/24 ,  A61B5/262 ,  A61B5/265 ,  A61B5/301

CPC classification number: A61B5/4255 ,  A61B5/065 ,  A61B5/2415 ,  A61B5/262 ,  A61B5/265 ,  A61B5/301 ,  A61B5/6847 ,  A61B90/08 ,  A61B2560/0468 ,  A61B2562/14

Abstract: A system for determining intestinal potential difference. The system includes a measurement probe including a measurement tube having a measurement lumen which houses a measurement electrode therein, a measurement fluid delivery system in fluid communication with the measurement lumen, the measurement fluid delivery system being configured to deliver an electrically-conductive fluid into the measurement lumen such that the electrically-conductive fluid is electrically coupled to the measurement electrode, and the measurement lumen including an outlet at a distal end thereof through which the electrically-conductive fluid exits the measurement lumen and contacts an intestinal tissue of a subject to provide electrical coupling between the measurement electrode and the intestinal tissue; a controller coupled to the measurement electrode configured to measure a potential difference between tire measurement electrode and a reference electrode electrically coupled to the subject.