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    Method of Immobilizing Protein, Protein Chip, Method of Immobilizing Cell and Cell Chip
    4.
    发明申请
    Method of Immobilizing Protein, Protein Chip, Method of Immobilizing Cell and Cell Chip 审中-公开
    固定蛋白，蛋白芯片，固定化细胞和细胞芯片的方法

    公开(公告)号：US20080248972A1

    公开(公告)日：2008-10-09

    申请号：US11579267

    申请日：2005-03-10

    申请人： Matsuhiko Nishizawa ,  Hirokazu Kaji ,  Tomokazu Matsue

    发明人： Matsuhiko Nishizawa ,  Hirokazu Kaji ,  Tomokazu Matsue

    IPC分类号： C40B50/18 ,  C07K14/00 ,  C07K16/00 ,  C12N11/08 ,  C07K14/76

    CPC分类号： G01N33/543 ,  B01J2219/00659 ,  B01J2219/00725 ,  B01J2219/00743

    摘要： It is intended to provide a novel method of immobilizing a protein and a protein chip, by which the protein can be immobilized at a high reproducibility while preventing the protein from inactivation without resort to a large-scaled apparatus and the protein can be immobilized even in a microchannel. Further, by using a cell adhesive protein as the protein to be immobilized, it is also possible to use a cell as a target and to provide a method of immobilizing a cell and a cell chip, by which a cell can be immobilized in an arbitrary region on a substrate.

    摘要翻译： 旨在提供一种固定蛋白质和蛋白质芯片的新方法，通过该方法可以以高再现性固定蛋白质，同时防止蛋白质失活而不需要大规模装置，并且即使在 一个微通道。 此外，通过使用细胞粘附蛋白作为待固定的蛋白质，还可以使用细胞作为靶，并提供固定细胞和细胞芯片的方法，通过其可以将细胞固定在任意的位置 区域。

    POROUS STRUCTURE PROVIDED WITH A PATTERN THAT IS COMPOSED OF CONDUCTIVE POLYMER AND METHOD OF MANUFACTURING THE SAME
    6.
    发明申请
    POROUS STRUCTURE PROVIDED WITH A PATTERN THAT IS COMPOSED OF CONDUCTIVE POLYMER AND METHOD OF MANUFACTURING THE SAME 有权
    具有由导电聚合物组成的图案的多孔结构及其制造方法

    公开(公告)号：US20130126220A1

    公开(公告)日：2013-05-23

    申请号：US13637494

    申请日：2011-03-25

    申请人： Matsuhiko Nishizawa ,  Soichiro Sekine ,  Yuichiro Ido

    发明人： Matsuhiko Nishizawa ,  Soichiro Sekine ,  Yuichiro Ido

    IPC分类号： C25D9/02 ,  H05K1/03

    CPC分类号： C25D9/02 ,  A61N1/0496 ,  C09D5/4407 ,  C09D5/4476 ,  H05K1/03 ,  H05K1/0313 ,  H05K1/0353

    摘要： A porous structure (1) provided with a pattern that is composed of a conductive polymer, which comprises a porous body (2) and a pattern (3) that is composed of a conductive polymer and arranged on the porous body (2). The porous body (2) is preferably a gel, and a dopant may be added to the pattern (3) that is composed of a conductive polymer. If an agarose gel is used as the gel (2) and a PEDOT electrode (3A) is used as the pattern (3) that is composed of a conductive polymer in the porous structure (1) which is provided with the pattern (3) that is composed of a conductive polymer, the porous structure (1) can be used as an electrode for cell stimulation. The porous structure (1) provided with the pattern (3) that is composed of a conductive polymer can be produced by an electropolymerization method.

    摘要翻译： 一种多孔结构（1），其具有由导电性聚合物构成的图案，所述导电性聚合物包含多孔体（2）和由导电性聚合物构成且配置在所述多孔体（2）上的图案）。 多孔体（2）优选为凝胶，并且可以向由导电性聚合物构成的图案（3）添加掺杂剂。 如果使用琼脂糖凝胶作为凝胶（2），并且使用PEDOT电极（3A）作为在具有图案（3）的多孔结构（1）中由导电性聚合物构成的图案（3） 由导电性聚合物构成，多孔结构体（1）可以用作细胞刺激用电极。 具有由导电性聚合物构成的图案（3）的多孔结构体（1）可以通过电聚合法制造。

    Electron mediator, electron mediator immobilized electrode, and biofuel cell using the electrode
    7.
    发明申请
    Electron mediator, electron mediator immobilized electrode, and biofuel cell using the electrode 有权
    电子介体，电子介体固定电极和使用电极的生物燃料电池

    公开(公告)号：US20050049313A1

    公开(公告)日：2005-03-03

    申请号：US10807489

    申请日：2004-03-23

    申请人： Matsuhiko Nishizawa ,  Tomokazu Matsue ,  Jun-ichi Kosuge ,  Noboru Fukasaku

    发明人： Matsuhiko Nishizawa ,  Tomokazu Matsue ,  Jun-ichi Kosuge ,  Noboru Fukasaku

    IPC分类号： C12M1/34 ,  C07C66/02 ,  C07C235/78 ,  H01M8/16 ,  A61K31/12

    CPC分类号： C07C66/02 ,  C07C235/78 ,  H01M8/16 ,  Y02E60/527 ,  Y10S435/817

    摘要： An object of the present invention is to provide a highly functional mediator capable of smoothly proceeding electron transfer between an electrode and a biocatalyst based on the premise that the mediator excels in safety and cost and to provide an electrode and a cell with sufficient amount of such a mediator molecule immobilized efficiently and strongly. The present invention provides a mediator mediating electron transfer between an enzyme and an electrode and containing a quinone molecule derivative, in particular, a mediator containing a VK3 derivative. In addition, the present invention provides an electrode and a biofuel cell to which those mediators are applied.

    摘要翻译： 本发明的目的是提供一种能够平稳地进行电极和生物催化剂之间的电子转移的高功能介体，其基于这样的前提，即介质优良的安全性和成本，并且提供具有足够量的这样的电极和电池 一种有效强固地固定的介体分子。 本发明提供介导酶和电极之间的电子转移并含有醌分子衍生物，特别是含有VK3衍生物的介体的介体。 此外，本发明提供一种电极和生物燃料电池，其中应用这些介体。

    Electron mediator, electron mediator immobilized electrode, and biofuel cell using the electrode
    8.
    发明授权
    Electron mediator, electron mediator immobilized electrode, and biofuel cell using the electrode 有权
    电子介体，电子介体固定电极和使用电极的生物燃料电池

    公开(公告)号：US07544438B2

    公开(公告)日：2009-06-09

    申请号：US10807489

    申请日：2004-03-23

    申请人： Matsuhiko Nishizawa ,  Tomokazu Matsue ,  Jun-ichi Kosuge ,  Noboru Fukasaku

    发明人： Matsuhiko Nishizawa ,  Tomokazu Matsue ,  Jun-ichi Kosuge ,  Noboru Fukasaku

    IPC分类号： H01M2/14 ,  H01M4/86 ,  C12Q1/00 ,  C12N11/08

    CPC分类号： C07C66/02 ,  C07C235/78 ,  H01M8/16 ,  Y02E60/527 ,  Y10S435/817

    摘要： An object of the present invention is to provide a highly functional mediator capable of smoothly proceeding electron transfer between an electrode and a biocatalyst based on the premise that the mediator excels in safety and cost and to provide an electrode and a cell with sufficient amount of such a mediator molecule immobilized efficiently and strongly. The present invention provides a mediator mediating electron transfer between an enzyme and an electrode and containing a quinone molecule derivative, in particular, a mediator containing a VK3 derivative. In addition, the present invention provides an electrode and a biofuel cell to which those mediators are applied.

    摘要翻译： 本发明的目的是提供一种能够平稳地进行电极和生物催化剂之间的电子转移的高功能介体，其基于这样的前提，即介质优良的安全性和成本，并且提供具有足够量的这样的电极和电池 一种有效强固地固定的介体分子。 本发明提供介导酶和电极之间的电子转移并含有醌分子衍生物，特别是含有VK3衍生物的介体的介体。 此外，本发明提供一种电极和生物燃料电池，其中应用这些介体。