公开(公告)号：US20140370058A1

公开(公告)日：2014-12-18

申请号：US14476791

申请日：2014-09-04

申请人： William Charles OHNESORGE ,  Isabelle FREIIN VON RICHTHOFEN ,  Marika Christine GENZOW ,  Martina VON FREYBURG ,  Carola KISSEL ,  Luc-Etienne FABRY ,  Knut ELBERS ,  Kathleen Kwan Young PARK

发明人： William Charles OHNESORGE ,  Isabelle FREIIN VON RICHTHOFEN ,  Marika Christine GENZOW ,  Martina VON FREYBURG ,  Carola KISSEL ,  Luc-Etienne FABRY ,  Knut ELBERS ,  Kathleen Kwan Young PARK

IPC分类号： A61K39/02

CPC分类号： A61K39/0241 ,  A61K39/40 ,  A61K2039/521 ,  A61K2039/552 ,  C12N1/20 ,  C12R1/35

摘要： The present invention provides a one phase, aqueous vaccine composition for immunizing an animal against infection by Mycoplasma hyopneumoniae, comprising: an immunizing amount of a Mycoplasma hyopneumoniae bacterin, an acrylic acid polymer in the concentration range between 0.8 and 1.2 mg/ml, and a pharmaceutically acceptable carrier, and substantially no oil. It is especially useful for immunizing a pig against infection by Mycoplasma hyopneumoniae for at least 20 weeks after a single administration, which effective immunity is reached within 4 weeks after vaccination.

摘要翻译： 本发明提供一种用于免疫动物免受猪肺炎支原体感染的单相水性疫苗组合物，其包含：免疫量的猪肺炎支原体菌苗，浓度范围为0.8-1.2mg / ml的丙烯酸聚合物和 药学上可接受的载体，基本上不含油。 在单次给药后至少20周免疫猪免于猪肺炎支原体感染特别有用，在接种后4周内有效免疫。

公开(公告)号：US20130230558A1

公开(公告)日：2013-09-05

申请号：US13869574

申请日：2013-04-24

申请人： Wiliam Charles OHNESORGE ,  Isabelle FREIIN VON RICHTHOFEN ,  Marika Christine GENZOW ,  Martina VON FREYBURG ,  Carola KISSEL ,  Luc-Etienne FABRY ,  Knut ELBERS ,  Kathleen Kwan Young PARK

发明人： Wiliam Charles OHNESORGE ,  Isabelle FREIIN VON RICHTHOFEN ,  Marika Christine GENZOW ,  Martina VON FREYBURG ,  Carola KISSEL ,  Luc-Etienne FABRY ,  Knut ELBERS ,  Kathleen Kwan Young PARK

IPC分类号： A61K39/02

CPC分类号： A61K39/0241 ,  A61K39/40 ,  A61K2039/521 ,  A61K2039/552 ,  C12N1/20 ,  C12R1/35

摘要： The present invention provides a one phase, aqueous vaccine composition for immunizing an animal against infection by Mycoplasma hyopneumoniae, comprising: an immunizing amount of a Mycoplasma hyopneumoniae bacterin, an acrylic acid polymer in the concentration range between 0.8 and 1.2 mg/ml, and a pharmaceutically acceptable carrier, and substantially no oil. It is especially useful for immunizing a pig against infection by Mycoplasma hyopneumoniae for at least 20 weeks after a single administration, which effective immunity is reached within 4 weeks after vaccination.

摘要翻译： 本发明提供一种用于免疫动物免受猪肺炎支原体感染的单相水性疫苗组合物，其包含：免疫量的猪肺炎支原体菌苗，浓度范围为0.8-1.2mg / ml的丙烯酸聚合物和 药学上可接受的载体，基本上不含油。 在单次给药后至少20周免疫猪免于猪肺炎支原体感染特别有用，在接种后4周内有效免疫。

公开(公告)号：US20140377298A1

公开(公告)日：2014-12-25

申请号：US14483097

申请日：2014-09-10

申请人： Vicky FACHINGER ,  Knut ELBERS ,  Axel LISCHEWSKI ,  Marion KIXMOELLER ,  Francois-Xavier ORVEILLON ,  Isabelle FREIIN VON RICHTHOFEN ,  Michael D. PIONTKOWSKI

发明人： Vicky FACHINGER ,  Knut ELBERS ,  Axel LISCHEWSKI ,  Marion KIXMOELLER ,  Francois-Xavier ORVEILLON ,  Isabelle FREIIN VON RICHTHOFEN ,  Michael D. PIONTKOWSKI

IPC分类号： A61K39/12 ,  C12N7/00

CPC分类号： A61K39/12 ,  A61K31/155 ,  A61K31/7036 ,  A61K2039/5252 ,  A61K2039/545 ,  A61K2039/55 ,  A61K2039/552 ,  A61K2039/55555 ,  C12N7/00 ,  C12N2750/10034

摘要： The present invention relates to a method for the treatment or prophylaxis of a PCV2 infection or for reduction of clinical symptoms caused by or associated with a PCV2 infection in animals a) having anti-PCV2 antibodies and/or b) being young piglets of 1 to 22 days of age, comprising the step of administering an effective amount of a PCV2 antigen to that animal in need of such treatment. Preferably, those animals are pigs or young piglets.

摘要翻译： 本发明涉及一种用于治疗或预防PCV2感染或减少由PCV2感染引起的或与动物相关的临床症状的方法a）具有抗PCV2抗体和/或b）是1至 22天龄，包括向需要这种治疗的动物施用有效量的PCV2抗原的步骤。 优选地，这些动物是猪或幼仔。

公开(公告)号：US20130115236A1

公开(公告)日：2013-05-09

申请号：US13729688

申请日：2012-12-28

申请人： Vicky FACHINGER ,  Knut ELBERS ,  Marion KIXMOELLER ,  Francois-Xavier ORVEILLON ,  Isabelle FREIIN VON RICHTHOFEN ,  Axel LISCHEWSKI

发明人： Vicky FACHINGER ,  Knut ELBERS ,  Marion KIXMOELLER ,  Francois-Xavier ORVEILLON ,  Isabelle FREIIN VON RICHTHOFEN ,  Axel LISCHEWSKI

IPC分类号： A61K39/12

CPC分类号： A61K39/12 ,  A61K2039/5256 ,  A61K2039/545 ,  A61K2039/552 ,  A61K2039/55555 ,  C12N7/00 ,  C12N2710/14043 ,  C12N2750/10022 ,  C12N2750/10034

摘要： The present invention relates to the use of an immunogenic composition comprising a porcine circovirus type 2 (PCV2) antigen for the prevention and treatment, including a reduction in the severity of, duration of, and manifestations of, porcine respiratory disease complex (PRDC) in animals, preferably in pigs.

公开(公告)号：US20130273099A1

公开(公告)日：2013-10-17

申请号：US13924811

申请日：2013-06-24

申请人： Vicky FACHINGER ,  Knut ELBERS ,  Marion KIXMOELLER ,  Francois-Xavier ORVEILLON ,  Isabelle FREIIN VON RICHTHOFEN ,  Axel LISCHEWSKI

发明人： Vicky FACHINGER ,  Knut ELBERS ,  Marion KIXMOELLER ,  Francois-Xavier ORVEILLON ,  Isabelle FREIIN VON RICHTHOFEN ,  Axel LISCHEWSKI

IPC分类号： A61K39/12

CPC分类号： A61K39/12 ,  A61K2039/5252 ,  A61K2039/5256 ,  A61K2039/552 ,  C12N7/00 ,  C12N2710/14041 ,  C12N2710/14043 ,  C12N2710/14143 ,  C12N2750/10034 ,  C12N2750/10071

摘要： The present invention relates to the use of an immunogenic composition comprising a porcine circovirus type 2 (PCV2) antigen for the prevention and treatment of sub-clinical PCV2 infection in animals, preferably in pigs.