公开(公告)号：US20140377298A1

公开(公告)日：2014-12-25

申请号：US14483097

申请日：2014-09-10

申请人： Vicky FACHINGER ,  Knut ELBERS ,  Axel LISCHEWSKI ,  Marion KIXMOELLER ,  Francois-Xavier ORVEILLON ,  Isabelle FREIIN VON RICHTHOFEN ,  Michael D. PIONTKOWSKI

发明人： Vicky FACHINGER ,  Knut ELBERS ,  Axel LISCHEWSKI ,  Marion KIXMOELLER ,  Francois-Xavier ORVEILLON ,  Isabelle FREIIN VON RICHTHOFEN ,  Michael D. PIONTKOWSKI

IPC分类号： A61K39/12 ,  C12N7/00

CPC分类号： A61K39/12 ,  A61K31/155 ,  A61K31/7036 ,  A61K2039/5252 ,  A61K2039/545 ,  A61K2039/55 ,  A61K2039/552 ,  A61K2039/55555 ,  C12N7/00 ,  C12N2750/10034

摘要： The present invention relates to a method for the treatment or prophylaxis of a PCV2 infection or for reduction of clinical symptoms caused by or associated with a PCV2 infection in animals a) having anti-PCV2 antibodies and/or b) being young piglets of 1 to 22 days of age, comprising the step of administering an effective amount of a PCV2 antigen to that animal in need of such treatment. Preferably, those animals are pigs or young piglets.

摘要翻译： 本发明涉及一种用于治疗或预防PCV2感染或减少由PCV2感染引起的或与动物相关的临床症状的方法a）具有抗PCV2抗体和/或b）是1至 22天龄，包括向需要这种治疗的动物施用有效量的PCV2抗原的步骤。 优选地，这些动物是猪或幼仔。

公开(公告)号：US20130115236A1

公开(公告)日：2013-05-09

申请号：US13729688

申请日：2012-12-28

申请人： Vicky FACHINGER ,  Knut ELBERS ,  Marion KIXMOELLER ,  Francois-Xavier ORVEILLON ,  Isabelle FREIIN VON RICHTHOFEN ,  Axel LISCHEWSKI

发明人： Vicky FACHINGER ,  Knut ELBERS ,  Marion KIXMOELLER ,  Francois-Xavier ORVEILLON ,  Isabelle FREIIN VON RICHTHOFEN ,  Axel LISCHEWSKI

IPC分类号： A61K39/12

CPC分类号： A61K39/12 ,  A61K2039/5256 ,  A61K2039/545 ,  A61K2039/552 ,  A61K2039/55555 ,  C12N7/00 ,  C12N2710/14043 ,  C12N2750/10022 ,  C12N2750/10034

摘要： The present invention relates to the use of an immunogenic composition comprising a porcine circovirus type 2 (PCV2) antigen for the prevention and treatment, including a reduction in the severity of, duration of, and manifestations of, porcine respiratory disease complex (PRDC) in animals, preferably in pigs.

公开(公告)号：US20130273099A1

公开(公告)日：2013-10-17

申请号：US13924811

申请日：2013-06-24

申请人： Vicky FACHINGER ,  Knut ELBERS ,  Marion KIXMOELLER ,  Francois-Xavier ORVEILLON ,  Isabelle FREIIN VON RICHTHOFEN ,  Axel LISCHEWSKI

发明人： Vicky FACHINGER ,  Knut ELBERS ,  Marion KIXMOELLER ,  Francois-Xavier ORVEILLON ,  Isabelle FREIIN VON RICHTHOFEN ,  Axel LISCHEWSKI

IPC分类号： A61K39/12

CPC分类号： A61K39/12 ,  A61K2039/5252 ,  A61K2039/5256 ,  A61K2039/552 ,  C12N7/00 ,  C12N2710/14041 ,  C12N2710/14043 ,  C12N2710/14143 ,  C12N2750/10034 ,  C12N2750/10071

摘要： The present invention relates to the use of an immunogenic composition comprising a porcine circovirus type 2 (PCV2) antigen for the prevention and treatment of sub-clinical PCV2 infection in animals, preferably in pigs.

公开(公告)号：US20130302370A1

公开(公告)日：2013-11-14

申请号：US13908766

申请日：2013-06-03

申请人： Vicky FACHINGER ,  Knut ELBERS ,  Marion KIXMOELLER

发明人： Vicky FACHINGER ,  Knut ELBERS ,  Marion KIXMOELLER

IPC分类号： A61K39/12 ,  A61K45/06

CPC分类号： A61K39/12 ,  A61K45/06 ,  A61K2039/552 ,  C12N2750/10034

摘要： The present invention relates to a method for reducing the percentage of concomitant infections in pigs or a herd of pigs caused by pathogens other than PCV2 comprising the step administering to said pig(s) an effective amount of PCV2 antigen or an immunogenic composition comprising PCV2 antigen. It also refers to a method for improving the resistance of pigs against concomitant infections with pathogens other than PCV2, comprising the step administering to said pig(s) an effective amount of PCV2 antigen or an immunogenic composition comprising PCV2 antigen.

公开(公告)号：US20110052629A1

公开(公告)日：2011-03-03

申请号：US12941836

申请日：2010-11-08

申请人： Vicky FACHINGER ,  Knut Elbers ,  Marion Kixmoeller

发明人： Vicky FACHINGER ,  Knut Elbers ,  Marion Kixmoeller

IPC分类号： A61K39/12 ,  A61P31/12 ,  A61P37/04

CPC分类号： A61K39/12 ,  A61K45/06 ,  A61K2039/552 ,  C12N2750/10034

摘要： The present invention relates to a method for reducing the percentage of concomitant infections in pigs or a herd of pigs caused by pathogens other than PCV2 comprising the step administering to said pig(s) an effective amount of PCV2 antigen or an immunogenic composition comprising PCV2 antigen. It also refers to a method for improving the resistance of pigs against concomitant infections with pathogens other than PCV2, comprising the step administering to said pig(s) an effective amount of PCV2 antigen or an immunogenic composition comprising PCV2 antigen.

摘要翻译： 本发明涉及一种降低由除PCV2以外的病原体引起的猪或猪群中伴随感染的百分比的方法，包括向所述猪施用有效量的PCV2抗原或包含PCV2抗原的免疫原性组合的步骤 。 本发明还涉及提高猪抗PCV2以外的病原体的伴随感染的抗性的方法，包括向所述猪施用有效量的PCV2抗原或包含PCV2抗原的免疫原性组合的步骤。

公开(公告)号：US20140234900A1

公开(公告)日：2014-08-21

申请号：US14176249

申请日：2014-02-10

申请人： Vicky FACHINGER ,  Melanie SNO

发明人： Vicky FACHINGER ,  Melanie SNO

IPC分类号： C07K1/14 ,  C12P21/00 ,  C07K14/005

CPC分类号： C12N7/00 ,  A61K39/00 ,  A61K2039/5258 ,  C07K1/14 ,  C12N2710/14043 ,  C12N2750/10023 ,  C12N2750/10051 ,  C12N2750/14023 ,  C12N2750/14051 ,  C12N2750/14323 ,  C12N2750/14351 ,  C12P21/00

摘要： The present invention relates to methods for the release of baculovirus-expressed Virus-like Particles (VLP's) of non-enveloped viruses from insect cells.

摘要翻译： 本发明涉及从昆虫细胞中释放非包膜病毒的杆状病毒表达的病毒样颗粒（VLP）的方法。