公开(公告)号：US20140377298A1

公开(公告)日：2014-12-25

申请号：US14483097

申请日：2014-09-10

申请人： Vicky FACHINGER ,  Knut ELBERS ,  Axel LISCHEWSKI ,  Marion KIXMOELLER ,  Francois-Xavier ORVEILLON ,  Isabelle FREIIN VON RICHTHOFEN ,  Michael D. PIONTKOWSKI

发明人： Vicky FACHINGER ,  Knut ELBERS ,  Axel LISCHEWSKI ,  Marion KIXMOELLER ,  Francois-Xavier ORVEILLON ,  Isabelle FREIIN VON RICHTHOFEN ,  Michael D. PIONTKOWSKI

IPC分类号： A61K39/12 ,  C12N7/00

CPC分类号： A61K39/12 ,  A61K31/155 ,  A61K31/7036 ,  A61K2039/5252 ,  A61K2039/545 ,  A61K2039/55 ,  A61K2039/552 ,  A61K2039/55555 ,  C12N7/00 ,  C12N2750/10034

摘要： The present invention relates to a method for the treatment or prophylaxis of a PCV2 infection or for reduction of clinical symptoms caused by or associated with a PCV2 infection in animals a) having anti-PCV2 antibodies and/or b) being young piglets of 1 to 22 days of age, comprising the step of administering an effective amount of a PCV2 antigen to that animal in need of such treatment. Preferably, those animals are pigs or young piglets.

摘要翻译： 本发明涉及一种用于治疗或预防PCV2感染或减少由PCV2感染引起的或与动物相关的临床症状的方法a）具有抗PCV2抗体和/或b）是1至 22天龄，包括向需要这种治疗的动物施用有效量的PCV2抗原的步骤。 优选地，这些动物是猪或幼仔。

公开(公告)号：US20130115236A1

公开(公告)日：2013-05-09

申请号：US13729688

申请日：2012-12-28

申请人： Vicky FACHINGER ,  Knut ELBERS ,  Marion KIXMOELLER ,  Francois-Xavier ORVEILLON ,  Isabelle FREIIN VON RICHTHOFEN ,  Axel LISCHEWSKI

发明人： Vicky FACHINGER ,  Knut ELBERS ,  Marion KIXMOELLER ,  Francois-Xavier ORVEILLON ,  Isabelle FREIIN VON RICHTHOFEN ,  Axel LISCHEWSKI

IPC分类号： A61K39/12

CPC分类号： A61K39/12 ,  A61K2039/5256 ,  A61K2039/545 ,  A61K2039/552 ,  A61K2039/55555 ,  C12N7/00 ,  C12N2710/14043 ,  C12N2750/10022 ,  C12N2750/10034

摘要： The present invention relates to the use of an immunogenic composition comprising a porcine circovirus type 2 (PCV2) antigen for the prevention and treatment, including a reduction in the severity of, duration of, and manifestations of, porcine respiratory disease complex (PRDC) in animals, preferably in pigs.

公开(公告)号：US20130273099A1

公开(公告)日：2013-10-17

申请号：US13924811

申请日：2013-06-24

申请人： Vicky FACHINGER ,  Knut ELBERS ,  Marion KIXMOELLER ,  Francois-Xavier ORVEILLON ,  Isabelle FREIIN VON RICHTHOFEN ,  Axel LISCHEWSKI

发明人： Vicky FACHINGER ,  Knut ELBERS ,  Marion KIXMOELLER ,  Francois-Xavier ORVEILLON ,  Isabelle FREIIN VON RICHTHOFEN ,  Axel LISCHEWSKI

IPC分类号： A61K39/12

CPC分类号： A61K39/12 ,  A61K2039/5252 ,  A61K2039/5256 ,  A61K2039/552 ,  C12N7/00 ,  C12N2710/14041 ,  C12N2710/14043 ,  C12N2710/14143 ,  C12N2750/10034 ,  C12N2750/10071

摘要： The present invention relates to the use of an immunogenic composition comprising a porcine circovirus type 2 (PCV2) antigen for the prevention and treatment of sub-clinical PCV2 infection in animals, preferably in pigs.

公开(公告)号：US20130302370A1

公开(公告)日：2013-11-14

申请号：US13908766

申请日：2013-06-03

申请人： Vicky FACHINGER ,  Knut ELBERS ,  Marion KIXMOELLER

发明人： Vicky FACHINGER ,  Knut ELBERS ,  Marion KIXMOELLER

IPC分类号： A61K39/12 ,  A61K45/06

CPC分类号： A61K39/12 ,  A61K45/06 ,  A61K2039/552 ,  C12N2750/10034

摘要： The present invention relates to a method for reducing the percentage of concomitant infections in pigs or a herd of pigs caused by pathogens other than PCV2 comprising the step administering to said pig(s) an effective amount of PCV2 antigen or an immunogenic composition comprising PCV2 antigen. It also refers to a method for improving the resistance of pigs against concomitant infections with pathogens other than PCV2, comprising the step administering to said pig(s) an effective amount of PCV2 antigen or an immunogenic composition comprising PCV2 antigen.

公开(公告)号：US20130230558A1

公开(公告)日：2013-09-05

申请号：US13869574

申请日：2013-04-24

申请人： Wiliam Charles OHNESORGE ,  Isabelle FREIIN VON RICHTHOFEN ,  Marika Christine GENZOW ,  Martina VON FREYBURG ,  Carola KISSEL ,  Luc-Etienne FABRY ,  Knut ELBERS ,  Kathleen Kwan Young PARK

发明人： Wiliam Charles OHNESORGE ,  Isabelle FREIIN VON RICHTHOFEN ,  Marika Christine GENZOW ,  Martina VON FREYBURG ,  Carola KISSEL ,  Luc-Etienne FABRY ,  Knut ELBERS ,  Kathleen Kwan Young PARK

IPC分类号： A61K39/02

CPC分类号： A61K39/0241 ,  A61K39/40 ,  A61K2039/521 ,  A61K2039/552 ,  C12N1/20 ,  C12R1/35

摘要： The present invention provides a one phase, aqueous vaccine composition for immunizing an animal against infection by Mycoplasma hyopneumoniae, comprising: an immunizing amount of a Mycoplasma hyopneumoniae bacterin, an acrylic acid polymer in the concentration range between 0.8 and 1.2 mg/ml, and a pharmaceutically acceptable carrier, and substantially no oil. It is especially useful for immunizing a pig against infection by Mycoplasma hyopneumoniae for at least 20 weeks after a single administration, which effective immunity is reached within 4 weeks after vaccination.

摘要翻译： 本发明提供一种用于免疫动物免受猪肺炎支原体感染的单相水性疫苗组合物，其包含：免疫量的猪肺炎支原体菌苗，浓度范围为0.8-1.2mg / ml的丙烯酸聚合物和 药学上可接受的载体，基本上不含油。 在单次给药后至少20周免疫猪免于猪肺炎支原体感染特别有用，在接种后4周内有效免疫。

公开(公告)号：US20140370058A1

公开(公告)日：2014-12-18

申请号：US14476791

申请日：2014-09-04

申请人： William Charles OHNESORGE ,  Isabelle FREIIN VON RICHTHOFEN ,  Marika Christine GENZOW ,  Martina VON FREYBURG ,  Carola KISSEL ,  Luc-Etienne FABRY ,  Knut ELBERS ,  Kathleen Kwan Young PARK

发明人： William Charles OHNESORGE ,  Isabelle FREIIN VON RICHTHOFEN ,  Marika Christine GENZOW ,  Martina VON FREYBURG ,  Carola KISSEL ,  Luc-Etienne FABRY ,  Knut ELBERS ,  Kathleen Kwan Young PARK

IPC分类号： A61K39/02

CPC分类号： A61K39/0241 ,  A61K39/40 ,  A61K2039/521 ,  A61K2039/552 ,  C12N1/20 ,  C12R1/35

摘要： The present invention provides a one phase, aqueous vaccine composition for immunizing an animal against infection by Mycoplasma hyopneumoniae, comprising: an immunizing amount of a Mycoplasma hyopneumoniae bacterin, an acrylic acid polymer in the concentration range between 0.8 and 1.2 mg/ml, and a pharmaceutically acceptable carrier, and substantially no oil. It is especially useful for immunizing a pig against infection by Mycoplasma hyopneumoniae for at least 20 weeks after a single administration, which effective immunity is reached within 4 weeks after vaccination.

摘要翻译： 本发明提供一种用于免疫动物免受猪肺炎支原体感染的单相水性疫苗组合物，其包含：免疫量的猪肺炎支原体菌苗，浓度范围为0.8-1.2mg / ml的丙烯酸聚合物和 药学上可接受的载体，基本上不含油。 在单次给药后至少20周免疫猪免于猪肺炎支原体感染特别有用，在接种后4周内有效免疫。

公开(公告)号：US20130156811A1

公开(公告)日：2013-06-20

申请号：US13765329

申请日：2013-02-12

申请人： Ricarda DEITMER ,  Knut ELBERS

发明人： Ricarda DEITMER ,  Knut ELBERS

IPC分类号： A61K39/02 ,  A61K31/7048

CPC分类号： A61K39/105 ,  A61K31/00 ,  A61K31/7048 ,  A61K2039/521 ,  A61K2039/522 ,  A61K2039/545 ,  A61K2039/552

摘要： The present invention relates inter alia to the use of a combination of a vaccine against Lawsonia intracellularis and an anti-Lawsonia antibiotic for the prevention or reduction of early, preferably fulminant Lawsonia intracellularis infections. The present invention relates particularly to the use of a live Lawsonia intracellularis vaccine in conjunction with an antibiotic that is effective against Lawsonia intracellularis, for the avoidance or reduction of early Lawsonia intracellularis infections in animals.

摘要翻译： 本发明尤其涉及使用针对胞内劳森氏菌的疫苗和抗劳森氏菌抗菌素的组合来预防或减少早期，优选暴发性的劳森氏菌细胞内感染。 本发明特别涉及一种活的劳氏细胞内毒素疫苗与抗菌素联合使用，该抗生素对细胞内劳森氏菌有效，以避免或减少动物中早期劳森氏菌感染。