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368 条记录 (耗时 0.042 秒)

    Degradable clostridial toxins
    92.
    发明授权
    Degradable clostridial toxins 有权
    可降解梭菌毒素

    公开(公告)号：US07998489B2

    公开(公告)日：2011-08-16

    申请号：US12192905

    申请日：2008-08-15

    申请人： Lance E. Steward ,  Ester G. Fernandez-Salas ,  Marcella A. Gilmore ,  Joseph Francis ,  Shengwen Li ,  Kei Roger Aoki

    发明人： Lance E. Steward ,  Ester G. Fernandez-Salas ,  Marcella A. Gilmore ,  Joseph Francis ,  Shengwen Li ,  Kei Roger Aoki

    IPC分类号： C07K14/00 ,  C07K14/33 ,  C07H21/04

    CPC分类号： C07K14/33 ,  C07K2319/33 ,  C07K2319/55

    摘要： The specification discloses modified Clostridial toxins comprising a PAR ligand domain, a Clostridial toxin enzymatic domain, a Clostridial toxin translocation domain and a Clostridial toxin binding domain; polynucleotide molecules encoding modified Clostridial toxins comprising a PAR ligand domain, a Clostridial toxin enzymatic domain, a Clostridial toxin translocation domain and a Clostridial toxin binding domain; and method of producing modified Clostridial toxins comprising a PAR ligand domain, a Clostridial toxin enzymatic domain, a Clostridial toxin translocation domain and a Clostridial toxin binding domain.

    摘要翻译： 该说明书公开了修饰的梭菌毒素，其包含PAR配体结构域，梭菌毒素酶促结构域，梭菌毒素易位结构域和梭菌毒素结合结构域; 编码经修饰的梭菌毒素的多核苷酸分子，其包含PAR配体结构域，梭菌毒素酶促结构域，梭菌毒素易位结构域和梭菌毒素结合结构域; 以及产生包含PAR配体结构域，梭菌毒素酶促结构域，梭菌毒素易位结构域和梭菌毒素结合结构域的修饰梭菌毒素的方法。

    System and method for the manufacture of surgical blades
    93.
    发明申请
    System and method for the manufacture of surgical blades 有权

    公开(公告)号：US20110192819A1

    公开(公告)日：2011-08-11

    申请号：US12929707

    申请日：2011-02-09

    申请人： Joseph Francis Keenan ,  Vadim Mark Daskal ,  James Joseph Hughes

    发明人： Joseph Francis Keenan ,  Vadim Mark Daskal ,  James Joseph Hughes

    IPC分类号： C23F1/00

    CPC分类号： A61B17/3211 ,  A61B17/32 ,  A61B2017/00526 ,  B28D5/022

    摘要： A method for manufacturing surgical blades from either a crystalline or poly-crystalline material, preferably in the form of a wafer, is disclosed. The method includes preparing the crystalline or poly-crystalline wafers by mounting them and machining trenches into the wafers. The methods for machining the trenches, which form the bevel blade surfaces, include a diamond blade saw, laser system, ultrasonic machine, and a hot forge press. The wafers are then placed in an etchant solution which isotropically etches the wafers in a uniform manner, such that layers of crystalline or poly-crystalline material are removed uniformly, producing single or double bevel blades. Nearly any angle can be machined into the wafer which remains after etching. The resulting radii of the blade edges is 5-500 nm, which is the same caliber as a diamond edged blade, but manufactured at a fraction of the cost.

    Memory card with embedded identifier
    94.
    发明授权
    Memory card with embedded identifier 有权
    具有嵌入式标识符的存储卡

    公开(公告)号：US07971017B1

    公开(公告)日：2011-06-28

    申请号：US11465951

    申请日：2006-08-21

    申请人： Joseph Francis Mann ,  William N. Schroeder

    发明人： Joseph Francis Mann ,  William N. Schroeder

    IPC分类号： G06F12/00

    CPC分类号： G06F21/123

    摘要： A software installation system comprises an interface component that receives a request to access data resident upon a flash memory card. An installation component compares a unique identifier associated with the data with a unique identifier embedded within the flash memory card, and the installation component determines whether to allow access to the data based at least in part upon the comparison. The installation component prohibits access to the data if the unique identifier associated with the data does not match the unique identifier embedded within the flash memory card.

    摘要翻译： 软件安装系统包括接收组件，其接收存储在闪存卡上的数据的请求。 安装部件将与数据相关联的唯一标识符与嵌入在闪存卡内的唯一标识符进行比较，并且安装部件至少部分地基于比较来确定是否允许访问数据。 如果与数据相关联的唯一标识符与嵌入闪存卡中的唯一标识符不匹配，则安装组件禁止访问数据。

    Proxy object configuration of industrial component
    95.
    发明授权
    Proxy object configuration of industrial component 有权
    代理对象配置工业组件

    公开(公告)号：US07966427B2

    公开(公告)日：2011-06-21

    申请号：US11529813

    申请日：2006-09-29

    申请人： Joseph Francis Mann

    发明人： Joseph Francis Mann

    IPC分类号： G06F13/10

    CPC分类号： H04L41/22 ,  G05B2219/23109 ,  G05B2219/23258 ,  H04L41/0253 ,  H04L41/0813 ,  H04L41/0853 ,  H04L41/0879

    摘要： An electrical device may be configured by coupling the device to a human machine interface (HMI) that is equipped with software for interacting with a configuration station. The software may include components that can enumerate properties of objects on the device to be configured. The device to be configured provides a file to the server-enabled HMI, such as a schema file. The server-enabled HMI then enumerates properties of the objects or otherwise provides an indication of the properties to the configuration station. The properties may be altered by a user at the configuration station. The reconfigured properties are then transmitted from the server-enabled HMI back to the device to be configured.

    摘要翻译： 电气设备可以通过将设备耦合到配备有用于与配置站进行交互的软件的人机界面（HMI）来配置。 该软件可以包括可以枚举要配置的设备上的对象的属性的组件。 要配置的设备会向启用了服务器的HMI提供文件，例如模式文件。 然后，启用服务器的HMI会枚举对象的属性，否则将向属性站提供属性的指示。 属性可能由配置站的用户改变。 然后将重新配置的属性从启用服务器的HMI发送回要配置的设备。

    System and method for the manufacture of surgical blades
    98.
    发明授权
    System and method for the manufacture of surgical blades 有权
    用于制造手术刀片的系统和方法

    公开(公告)号：US07906437B2

    公开(公告)日：2011-03-15

    申请号：US11495895

    申请日：2006-07-31

    申请人： Joseph Francis Keenan ,  Vadim Mark Daskal ,  James Joseph Hughes

    发明人： Joseph Francis Keenan ,  Vadim Mark Daskal ,  James Joseph Hughes

    IPC分类号： H01L21/302 ,  H01L21/461

    CPC分类号： A61B17/3211 ,  A61B17/32 ,  A61B2017/00526 ,  B28D5/022

    摘要： A method for manufacturing surgical blades from either a crystalline or poly-crystalline material, preferably in the form of a wafer, is disclosed. The method includes preparing the crystalline or poly-crystalline wafers by mounting them and machining trenches into the wafers. The methods for machining the trenches, which form the bevel blade surfaces, include a diamond blade saw, laser system, ultrasonic machine, and a hot forge press. The wafers are then placed in an etchant solution which isotropically etches the wafers in a uniform manner, such that layers of crystalline or poly-crystalline material are removed uniformly, producing single or double bevel blades. Nearly any angle can be machined into the wafer which remains after etching. The resulting radii of the blade edges is 5-500 nm, which is the same caliber as a diamond edged blade, but manufactured at a fraction of the cost.

    摘要翻译： 公开了一种从晶体或多晶材料制造手术刀片的方法，优选以晶片的形式。 该方法包括通过安装晶片或多晶晶片并将沟槽加工到晶片中来制备。 用于加工形成斜面刀片表面的沟槽的方法包括金刚石刀片锯，激光系统，超声波机器和热锻压机。 然后将晶片放置在蚀刻剂溶液中，其均匀地蚀刻晶片，使得均匀地去除晶体或多晶材料层，产生单斜面或双斜面叶片。 在蚀刻后保留的晶片中几乎可以加工任何角度。 叶片边缘的最终半径为5-500nm，其与金刚石边缘刀片相同的口径，但是以成本的一小部分制造。

    Combination heat recovery—solar collector
    100.
    发明授权
    Combination heat recovery—solar collector 失效
    组合热回收 - 太阳能集热器

    公开(公告)号：US07694673B2

    公开(公告)日：2010-04-13

    申请号：US11607572

    申请日：2006-12-04

    申请人： Joseph Francis Brown, Jr.

    发明人： Joseph Francis Brown, Jr.

    IPC分类号： F24J2/04

    CPC分类号： F24F5/0046 ,  F24D12/02 ,  F24D2200/12 ,  F24D2200/18 ,  F24F1/022 ,  F24F2005/0064 ,  F24S20/30 ,  F24S20/40 ,  F24S70/60 ,  F24S90/00 ,  Y02A30/272 ,  Y02B10/20 ,  Y02B10/24 ,  Y02B10/30 ,  Y02B10/70 ,  Y02B30/14 ,  Y02B30/52 ,  Y02E10/44 ,  Y02E10/465

    摘要： This invention absorbs available heat from the flue gas of an existing building's heating system and heat from the sun. The heat is absorbed and stored in a heat-collecting sphere of special design. The absorbed heat collected in the sphere is transferred, by the conventional refrigeration cycle, to the heat exchanger located at the air inlet to the building heating system. The refrigerant liquid is sprayed into the collecting sphere, as it absorbs heat, it evaporates and changes into a gas. The refrigerant compressor transfers the gas from the heat-collector to the heat exchanger. The existing heater fan draws air across the heat exchanger finned coil removing heat from the refrigerant. The refrigerant gas gives up heat and is condensed. The heated air combines with the existing furnace air to heat the existing building. The refrigerant liquid from the heat exchanger is transferred to the heat-collecting sphere spray nozzles.

    摘要翻译： 本发明吸收来自现有建筑物的供暖系统的烟道气和来自太阳的热量的可用热量。 热被吸收并储存在特殊设计的集热球体中。 在球体中收集的吸收的热量通过传统的制冷循环转移到位于建筑物加热系统的进气口处的热交换器。 制冷剂液体在吸收热量时被喷射到集尘球中，蒸发并变成气体。 制冷剂压缩机将气体从集热器传送到热交换器。 现有的加热器风扇通过热交换器翅片卷取空气，从制冷剂中除去热量。 制冷剂气体放出热量并冷凝。 加热的空气与现有的炉子空气结合，以加热现有的建筑物。 来自热交换器的制冷剂液体被传送到集热球喷嘴。