公开(公告)号：US20170266146A1

公开(公告)日：2017-09-21

申请号：US15532116

申请日：2015-12-03

Applicant: MOR RESEARCH APPLICATIONS LTD.

Inventor： Zeev DVASHI ,  Ayala POLLACK

IPC: A61K31/223 ,  A61K9/00 ,  A61K31/40

CPC classification number: A61K31/223 ,  A61K9/0019 ,  A61K9/0048 ,  A61K9/0051 ,  A61K31/40 ,  A61K38/05 ,  A61K45/06 ,  A61P25/28 ,  A61P27/02 ,  A61K2300/00

Abstract: This disclosure relates to compositions for use in treatment of Alzheimer's Disease, and/or a ocular and retinal degenerative disease, such as age related macular degeneration. The described compositions include effective amounts of LLMe, the hydrobromide form thereof, or functional derivatives thereof. Methods of treatment of a retinal degenerative disease of Alzheimer's Disease using the described compositions are also provided.

公开(公告)号：US20170247422A1

公开(公告)日：2017-08-31

申请号：US15596396

申请日：2017-05-16

Applicant: MOR - RESEARCH APPLICATIONS LTD. ,  RAPPAPORT FAMILY INSTITUTE FOR RESEARCH IN THE MEDICAL SCIENCES

Inventor： Michal A. RAHAT ,  Nitza LAHAT ,  Miriam WALTER ,  Haim BITTERMAN

IPC: C07K14/435 ,  C07K16/28 ,  G01N33/68 ,  C12N15/62 ,  G01N33/574 ,  C07K14/705 ,  C07K7/08

CPC classification number: C07K14/435 ,  A61K38/00 ,  A61K2039/505 ,  C07K7/06 ,  C07K7/08 ,  C07K14/705 ,  C07K16/2803 ,  C07K2317/34 ,  C07K2317/76 ,  C12N15/62 ,  G01N33/57484 ,  G01N33/68 ,  G01N2333/70596 ,  G16H50/30 ,  Y02A90/26

Abstract: Isolated peptides from the protein EMMPRIN (CD147/Basigin) and antibodies directed against antigenic determinants within the peptides. Pharmaceutical compositions including the peptides and antibodies and methods of their production and use in vaccination, immunotherapy and diagnosis of proliferative, hyperpermeability, inflammatory, and angiogenesis-related diseases and disorders.

公开(公告)号：US20170189376A1

公开(公告)日：2017-07-06

申请号：US15397780

申请日：2017-01-04

Applicant: MOR RESEARCH APPLICATIONS LTD. ,  BAR-ILAN UNIVERSITY

Inventor： Lilach Moyal ELCHARAR ,  Emmilia HODAK ,  Ada REPHAELI ,  Abraham NUDELMAN

IPC: A61K31/385 ,  A61K31/704 ,  A61K45/06

CPC classification number: A61K31/385 ,  A61K31/704 ,  A61K45/06 ,  A61K2300/00

Abstract: Methods for treating ameliorating, reducing and/or preventing a cutaneous T-cell lymphoma in a subject in need thereof, comprising administration butyroyloxymethyl diethyl phosphate (AN-7) alone or combined with an additional anti-cancer therapy.

公开(公告)号：US09688732B2

公开(公告)日：2017-06-27

申请号：US14502757

申请日：2014-09-30

Applicant: Rappaport Family Institute for Research in the Medical Sciences ,  Mor-Research Applications Ltd.

Inventor： Michal A. Rahat ,  Nitza Lahat ,  Miriam Walter ,  Haim Bitterman

IPC: A61K39/00 ,  A61K38/00 ,  C07K14/435 ,  C07K14/705 ,  C12N15/62 ,  G01N33/574 ,  C07K16/28 ,  C07K7/06 ,  C07K7/08 ,  G01N33/68 ,  G06F19/00

CPC classification number: C07K14/435 ,  A61K38/00 ,  A61K2039/505 ,  C07K7/06 ,  C07K7/08 ,  C07K14/705 ,  C07K16/2803 ,  C07K2317/34 ,  C07K2317/76 ,  C12N15/62 ,  G01N33/57484 ,  G01N33/68 ,  G01N2333/70596 ,  G06F19/00 ,  G16H50/30 ,  Y02A90/26

Abstract: Isolated peptides from the protein EMMPRIN (CD147/Basigin) and antibodies directed against antigenic determinants within the peptides. Pharmaceutical compositions including the peptides and antibodies and methods of their production and use in vaccination, immunotherapy and diagnosis of proliferative, hyperpermeability, inflammatory, and angiogenesis-related diseases and disorders.

公开(公告)号：US20160243055A1

公开(公告)日：2016-08-25

申请号：US15143694

申请日：2016-05-02

Applicant: MOR RESEARCH APPLICATIONS LTD.

Inventor： Moshe YESHURUN

IPC: A61K31/05 ,  A61K45/06 ,  A61K31/573 ,  A61K9/00

CPC classification number: A61K31/05 ,  A61K9/0014 ,  A61K9/0053 ,  A61K9/0095 ,  A61K45/06

Abstract: The invention provides methods for preventing, ameliorating and treating the acute and chronic forms of graft-versus-host disease (GVHD) by using Cannabidiol compositions.

Abstract translation: 本发明提供了通过使用大麻素组合物预防，改善和治疗急性和慢性形式的移植物抗宿主病（GVHD）的方法。

公开(公告)号：US09402565B2

公开(公告)日：2016-08-02

申请号：US14874498

申请日：2015-10-05

Applicant: Mor Research Applications Ltd. ,  Ramot at Tel-Aviv University Ltd.

Inventor： Yehuda Finkelstein ,  Lior Wolf

IPC: G06K9/00 ,  A61B5/107 ,  G06T7/00 ,  A61B5/00 ,  A61B5/08 ,  G06K9/46

CPC classification number: A61B5/1075 ,  A61B5/08 ,  A61B5/4818 ,  G06K9/46 ,  G06T7/0014 ,  G06T7/33 ,  G06T2200/04 ,  G06T2207/10116 ,  G06T2207/30008 ,  G06T2207/30036 ,  G06T2207/30196

Abstract: In a method of analysis, a target image is registered to define a plurality of keypoints arranged in sets corresponding to polygons or linear segments in the target image. A database of registered and annotated images is accessed and a polygon-wise comparison between the target image and each database image is employed. The comparison is used for projecting annotated locations from the database images into the target image.

公开(公告)号：US20150351663A1

公开(公告)日：2015-12-10

申请号：US14762819

申请日：2014-01-24

Applicant: B.G. NEGEV TECHNOLOGIES AND APPLICATIONS LTD. ,  MOR RESEARCH APPLICATIONS LTD.

Inventor： Yaniv ZIGEL ,  Ariel TARASIUK ,  Oren ELISHA

IPC: A61B5/08 ,  A61B5/00 ,  A61B7/00

CPC classification number: A61B5/0826 ,  A61B5/4803 ,  A61B5/4818 ,  A61B5/7278 ,  A61B7/003

Abstract: A method of determining a value for an apnea-hypopnea index (AHI) for a person, the method comprising: recording a voice track of a person; extracting features from the voice track that characterize the voice track; and processing the features to determine an AHI.

Abstract translation: 一种确定人的呼吸暂停 - 呼吸不足指数（AHI）的值的方法，所述方法包括：记录人的语音轨迹; 从语音轨道中提取表征语音轨道的特征; 并处理特征以确定AHI。

公开(公告)号：US09153022B2

公开(公告)日：2015-10-06

申请号：US13827111

申请日：2013-03-14

Applicant: Mor Research Applications Ltd. ,  Ramot at Tel-Aviv University Ltd.

Inventor： Yehuda Finkelstein ,  Lior Wolf

IPC: G06K9/00 ,  G06T7/00 ,  A61B5/107 ,  A61B5/00

CPC classification number: A61B5/1075 ,  A61B5/08 ,  A61B5/4818 ,  G06K9/46 ,  G06T7/0014 ,  G06T7/33 ,  G06T2200/04 ,  G06T2207/10116 ,  G06T2207/30008 ,  G06T2207/30036 ,  G06T2207/30196

Abstract: In a method of analysis, a target image is registered to define a plurality of keypoints arranged in sets corresponding to polygons or linear segments in the target image. A database of registered and annotated images is accessed and a polygon-wise comparison between the target image and each database image is employed. The comparison is used for projecting annotated locations from the database images into the target image.

Abstract translation: 在分析方法中，记录目标图像以定义与目标图像中的多边形或线性段对应的集合排列的多个关键点。 访问注册和注释的图像的数据库，并且采用目标图像和每个数据库图像之间的多边形比较。 比较用于将数据库图像中的注释位置投影到目标图像中。

公开(公告)号：US20150150497A1

公开(公告)日：2015-06-04

申请号：US14415591

申请日：2013-07-18

Applicant: Mor Research Applications Ltd.

Inventor： Chen Goldchmit

IPC: A61B5/00 ,  A61B8/12 ,  A61B1/303 ,  A61B1/012 ,  A61B1/015 ,  A61B1/06 ,  A61B1/018 ,  A61B17/32 ,  A61B1/00 ,  A61B8/08 ,  A61B8/00

CPC classification number: A61B5/4325 ,  A61B1/0005 ,  A61B1/0125 ,  A61B1/015 ,  A61B1/018 ,  A61B1/063 ,  A61B1/303 ,  A61B5/1076 ,  A61B8/0858 ,  A61B8/12 ,  A61B8/445 ,  A61B8/4494 ,  A61B8/463 ,  A61B8/5207 ,  A61B17/320016 ,  A61B2017/0034 ,  A61B2017/4216 ,  A61B2018/00559 ,  A61B2090/062

Abstract: According to an aspect of some embodiments of the present invention there is provided a probe sized for insertion into a uterus, the device comprising at least one ultrasound element adapted to emit ultrasonic energy, the ultrasound element disposed on a distal end of the device; at least one ultrasound receiver adapted to receive ultrasound energy, the ultrasound receiver disposed on a distal end of the device; and circuitry adapted to automatically estimate a thickness of a uterine wall according to the received ultrasound energy.According to an aspect of some embodiments of the present invention there is provided a method of treating an inner wall of a uterus comprising automatically measuring a thickness of a uterine wall according to ultrasound energy emitted from inside the uterus; and providing an output of the thickness.

Abstract translation: 根据本发明的一些实施例的一个方面，提供了尺寸适于插入子宫的探针，所述装置包括适于发射超声能量的至少一个超声元件，所述超声元件设置在所述装置的远端; 适于接收超声能量的至少一个超声波接收器，所述超声波接收器设置在所述装置的远端; 以及适于根据所接收的超声能量自动估计子宫壁的厚度的电路。 根据本发明的一些实施例的一个方面，提供了一种治疗子宫内壁的方法，包括根据从子宫内发射的超声能量自动测量子宫壁的厚度; 并提供厚度的输出。

公开(公告)号：US20140349874A1

公开(公告)日：2014-11-27

申请号：US14299792

申请日：2014-06-09

Applicant: Mor Research Applications Ltd.

Inventor： Offer AMIR ,  Basil S. LEWIS

IPC: C12Q1/68

CPC classification number: C12Q1/6883 ,  C12Q2600/118 ,  C12Q2600/156 ,  C12Q2600/16

Abstract: One or more polymorphisms, including single nucleotide polymorphisms (SNPs), or combinations thereof, for diagnosis of cardiac disease, such as heart failure and atrial fibrillation.

Abstract translation: 一种或多种多态性，包括单核苷酸多态性（SNPs）或其组合，用于诊断心脏病，如心力衰竭和心房颤动。