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公开(公告)号：US20070278155A1
公开(公告)日：2007-12-06
申请号：US11530842
申请日：2006-09-11
IPC分类号： A61M37/00
CPC分类号： A61M1/1639 , A61M1/16 , A61M1/1603 , A61M1/1605 , A61M1/1635 , A61M1/166 , A61M1/28 , A61M1/284 , A61M1/34 , A61M1/3627 , A61M2205/127 , A61M2205/3331 , A61M2205/3368 , A61M2205/502 , Y10T29/49826
摘要： A kidney failure therapy system includes: (a) a dilaysate supply; (b) at least one valve actuator; (c) at least one pump actuator; and (d) a disposable unit including first and second flexible sheets sealed together for form: (i) at least one flow path configured to be placed in fluid communication with the dilaysate supply; and operable with the at least one valve actuator; and (ii) at least one pumping portion configured to operate with the at least one pump actuator.
摘要翻译： 肾衰竭治疗系统包括：（a）稀释供应; （b）至少一个阀致动器; （c）至少一个泵致动器; 和（d）包括密封在一起的第一和第二柔性片的一次性单元，用于形成：（i）至少一个流路，被配置为与所述稀释片供应流体连通; 并且可与所述至少一个阀致动器一起操作; 和（ii）配置成与所述至少一个泵致动器一起操作的至少一个泵送部分。
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公开(公告)号：US5445792A
公开(公告)日：1995-08-29
申请号：US237406
申请日：1994-05-02
CPC分类号： A61L2/20
摘要： A sterilization method is provided which includes the steps of measuring the pressure within a sterilization chamber injecting a sterilant vapor into a flow of carrier gas, introducing the sterilant vapor and carrier gas into and through a sterilization chamber, and adjusting the rate of sterilant vapor injection to reach a pre-determined percentage of saturation limit for the sterilant vapor in the chamber, immediately following the introduction of sterilant vapor and carrier gas into the chamber, in response to the measured pressure. The predetermined saturation limit is selected to optimize the rate of sterilization, while avoiding substantial condensation of the sterilant.
摘要翻译： 提供灭菌方法，其包括以下步骤：测量灭菌室内的压力，将消毒剂蒸气注入载气流中，将消毒剂蒸气和载气引入灭菌室并通过灭菌室，并调节灭菌剂蒸汽注入速率 以响应于测量的压力，在灭菌剂蒸气和载气引入到室中之后立即达到室中灭菌蒸气的饱和限度的预定百分比。 选择预定的饱和极限以优化灭菌速率，同时避免灭菌剂的大量冷凝。
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公开(公告)号：US5232095A
公开(公告)日：1993-08-03
申请号：US686097
申请日：1991-04-16
IPC分类号： B65D81/02
CPC分类号： B65D81/02
摘要： An apparatus for shipping goods which must be maintained in a predetermined orientation is provided. A closable outer container has a shaft passing through it along an axis. A weighted closable inner container is rotatably mounted about this axis so that it may freely rotate within the outer container while always assuming a predetermined orientation.
摘要翻译： 提供了必须保持在预定方位上的用于运输货物的装置。 一个可关闭的外部容器具有沿轴线穿过它的轴。 加重的可关闭的内部容器围绕该轴线可旋转地安装，使得其可以在外部容器内自由旋转，同时始终采取预定取向。
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公开(公告)号：US09242034B2
公开(公告)日：2016-01-26
申请号：US13493743
申请日：2012-06-11
申请人： Robert W. Childers , Patrick Lee , Andrey Kopychev , Douglas Reitz , Rodolfo Roger , John F. Steck
发明人： Robert W. Childers , Patrick Lee , Andrey Kopychev , Douglas Reitz , Rodolfo Roger , John F. Steck
CPC分类号： A61M1/14 , A61M1/1601 , A61M1/1621 , A61M5/162 , A61M5/1626 , A61M39/165 , A61M2205/12 , A61M2205/128 , Y10T29/49826
摘要： A dialysis system includes a dialysis machine including at least one fluid pump, and an autoconnection mechanism including a moveable holder; a plurality of pierceable connectors each held by the moveable holder of the autoconnection mechanism, each of the pierceable connectors in fluid communication with a source of medical fluid; a plurality of spikes each held fixed by the dialysis machine, each of the spikes in fluid communication with a disposable component that is positioned and arranged to operate with the at least one fluid pump; and wherein the moveable holder is moved automatically by the autoconnection mechanism, so that (i) the spikes pierce the pierceable connectors and (ii) the sources of medical fluid can communicate with the disposable component positioned and arranged to operate with the at least one fluid pump.
摘要翻译： 透析系统包括透析机，其包括至少一个流体泵，以及包括可移动保持器的自动连接机构; 多个可刺穿连接器，每个可刺穿连接器由所述自动连接机构的可移动保持件保持，每个所述可刺穿连接器与医用流体源流体连通; 多个尖峰每个由所述透析机保持固定，每个所述尖峰与一次性部件流体连通，所述一次性部件被定位和布置成与所述至少一个流体泵一起操作; 并且其中所述可移动保持器由所述自动连接机构自动移动，使得（i）所述钉刺穿所述可刺穿连接器，并且（ii）所述医用流体源可与所述一次性部件连通，所述一次性部件定位和布置成与所述至少一种流体 泵。
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95.发明授权Dialysis system having filtering method for determining therapy prescriptions 有权具有用于确定治疗处方的过滤方法的透析系统公开(公告)号：US09149570B2
公开(公告)日：2015-10-06
申请号：US13438551
申请日：2012-04-03
CPC分类号： A61M1/28 , A61M1/1601 , A61M1/1613 , A61M1/281 , A61M1/282 , A61M2205/502 , A61M2205/52 , B01D61/30 , B01D61/32 , G06F19/00 , G06F19/3481
摘要： A peritoneal dialysis system includes a logic implementer configured to: (i) generate a number of peritoneal dialysis therapy regimens that meet at least one therapy target input; (ii) accept a filter input; and (iii) filter the generated therapy regimens according to the filter input to refine the number of therapy regimens available for selection.
摘要翻译： 腹膜透析系统包括逻辑实施器，其被配置为：（i）产生满足至少一个治疗目标输入的多个腹膜透析治疗方案; （ii）接受过滤器输入; 和（iii）根据过滤器输入过滤所产生的治疗方案以改善可用于选择的治疗方案的数量。
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公开(公告)号：US09147045B2
公开(公告)日：2015-09-29
申请号：US12170193
申请日：2008-07-09
CPC分类号： G06F19/3481 , A61M1/28 , A61M1/282 , A61M1/287 , A61M2205/12 , A61M2205/3553 , A61M2205/3584 , A61M2205/3592 , A61M2205/52 , G06F19/00 , G16H15/00 , G16H40/20 , G16H50/50
摘要： An ultrafiltration (“UF”) evaluation method includes: (i) determining an amount of UF removed from a patient over a first dwell time; (ii) determine an amount of UF removed from the patient over a second, different dwell time; (iii) determining an amount of UF removed from the patient over a third, different dwell time; and (iv) fitting a curve to the UF removal amounts for the first, second and third dwell time. A peritoneal dialysis therapy generation method using the curve determined according to the “UF” evaluation method to generate at least one peritoneal dialysis therapy regimen.
摘要翻译： 超滤（“UF”）评估方法包括：（i）确定在第一停留时间内从患者移除的UF的量; （ii）确定在第二个不同的停留时间内从患者移除的UF的量; （iii）确定在三分之一不同的停留时间内从患者移除的UF的量; 和（iv）将曲线拟合到第一，第二和第三停留时间的UF去除量。 使用根据“UF”评估方法确定的曲线产生至少一个腹膜透析治疗方案的腹膜透析治疗产生方法。
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公开(公告)号：US09132222B2
公开(公告)日：2015-09-15
申请号：US13458625
申请日：2012-04-27
摘要： A system and method for automatically adjusting a Continuous Cycling Peritoneal Dialysis (“CCPD”) therapy to minimize the potential for excess intra-peritoneal volume. The adjustments are made at the end of the drain, just prior to the next fill. The adjustments short the next fill, if necessary, to limit the intra-peritoneal volume, add a cycle, if necessary, to use all of the available dialysis solution and will average the remaining dwell time to maximize the therapeutic benefit of the therapy in the allotted time. In another embodiment, a tidal therapy using trended patient UF data is provided.
摘要翻译： 一种用于自动调节连续循环腹膜透析（“CCPD”）治疗的系统和方法，以最大限度地减少腹膜内多余的体积。 调整是在排水结束时进行的，就在下一次填充之前。 如果需要，调整缩短下一次填充，以限制腹膜内体积，如果需要，添加一个循环，以使用所有可用的透析溶液，并将平均剩余停留时间，以最大化治疗的治疗效果 分配时间 在另一个实施例中，提供使用趋势化患者UF数据的潮汐治疗。
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公开(公告)号：US08496609B2
公开(公告)日：2013-07-30
申请号：US11773522
申请日：2007-07-05
申请人： Robert W. Childers , Patrick Lee , Andrey Kopychev , Douglas Reitz , Rodolfo Roger , John E. Steck
发明人： Robert W. Childers , Patrick Lee , Andrey Kopychev , Douglas Reitz , Rodolfo Roger , John E. Steck
CPC分类号： A61M1/14 , A61M1/1601 , A61M1/1621 , A61M5/162 , A61M5/1626 , A61M39/165 , A61M2205/12 , A61M2205/128 , Y10T29/49826
摘要： A fluid dispensing machine, such as a peritoneal dialysis or hemodialysis machine, includes a dispenser or cassette that pumps a medical fluid for dialysis or other treatments for patients. The machine includes and uses an autoconnect device for connecting containers of liquid, such as bags of dialysis fluid or medication fluids, to the machine, while maintaining the sterility of the connection. The autoconnect device removes the cap from the fluid bag and pierces a sealing membrane on tubing from the bag. This makes it easier for patients to receive treatment, especially home treatment. The cassettes preferably have tubing ports with integral spikes for piercing the membrane on tubing from bags of liquids. The ports may be staggered for sequential engagement with the spikes. Other embodiments are useful for dispensing other liquids from other types of dispensing or pumping machines.
摘要翻译： 流体分配机器，例如腹膜透析或血液透析机，包括泵送用于患者的透析或其它治疗的医用流体的分配器或盒。 该机器包括并使用自动连接装置，用于将诸如透析液或药液的液体容器连接到机器上，同时保持连接的无菌性。 自动连接装置从流体袋中取出盖子，并将袋子上的管道上的密封膜刺穿。 这使患者更容易接受治疗，特别是家庭治疗。 盒子优选地具有带有整体尖峰的管道端口，用于在液体袋上的管道上刺穿膜。 端口可以交错以与钉相连接。 其他实施例可用于从其他类型的分配或泵送机器分配其它液体。
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99.发明授权Dialysis systems and methods having disposable cassette and interface therefore 有权透析系统和方法具有一次性盒式及接口公开(公告)号：US08328758B2
公开(公告)日：2012-12-11
申请号：US13047219
申请日：2011-03-14
IPC分类号： A61M37/00
CPC分类号： A61M1/28 , A61M1/16 , A61M1/1605 , A61M1/166 , A61M1/284 , A61M1/288 , A61M1/341 , A61M2205/122 , A61M2205/18 , A61M2205/3317 , A61M2205/3324 , A61M2205/3331 , A61M2205/3334 , A61M2205/3368
摘要： A medical fluid flow control system comprises an interface including a pump actuator port and a pump seal port, a membrane gasket including a pump actuation area and a pump aperture, and a pumping cassette including a flexible sheet and defining a pump chamber, a pump portion of the flexible sheet covering the pump chamber. The pump seal port is operable with the pump aperture to seal the pump portion of the flexible sheet to the pump actuation area of the membrane gasket and the pump actuator port is configured to move the pump portion of the flexible sheet and the pump actuation area of the membrane gasket at the pump chamber of the cassette.
摘要翻译： 医疗流体流量控制系统包括包括泵致动器端口和泵密封端口的接口，包括泵致动区域和泵孔的膜垫片，以及包括柔性片并限定泵室的泵送盒，泵部分 的柔性片覆盖泵室。 泵密封端口可与泵孔一起操作以将柔性片的泵部分密封到膜垫片的泵致动区域，并且泵致动器端口构造成使柔性片的泵部分和泵致动区域 盒式泵室的膜垫片。
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公开(公告)号：US20120271273A1
公开(公告)日：2012-10-25
申请号：US13493748
申请日：2012-06-11
申请人： Robert W. Childers , Patrick Lee , Andrey Kopychev , Douglas Reitz , Rodolfo Roger , John F. Steck
发明人： Robert W. Childers , Patrick Lee , Andrey Kopychev , Douglas Reitz , Rodolfo Roger , John F. Steck
IPC分类号： A61M5/168
CPC分类号： A61M1/14 , A61M1/1601 , A61M1/1621 , A61M5/162 , A61M5/1626 , A61M39/165 , A61M2205/12 , A61M2205/128 , Y10T29/49826
摘要： A medical fluid autoconnection method includes: enabling acceptance a pierceable connector that is capable of fluidly communicating with a source of medical fluid into a moveable holder; temporarily fixing a spike to a medical fluid pumping machine; automatically detecting whether the pierceable connector has been placed into the moveable holder; if the pierceable connector is sensed as being placed in the moveable holder, moving the holder so that the spike pierces the pierceable connector; and enabling medical fluid to be pumped from the source through the connected spiked and connector.
摘要翻译： 医疗流体自动连接方法包括：使得能够将能够与医疗流体源流体连通的可穿刺连接器接纳到可移动保持器中; 临时固定尖头到医用液体泵送机器; 自动检测可穿刺连接器是否已经被放置在可移动支架中; 如果可刺穿的连接器被感测为放置在可移动的保持器中，则移动保持器，使得尖钉刺穿可刺穿的连接器; 并且使得能够从源通过连接的加标和连接器泵送医用流体。
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