公开(公告)号：US10012660B2

公开(公告)日：2018-07-03

申请号：US15834441

申请日：2017-12-07

申请人： David R. Hall ,  Conrad Rosenbrock ,  Ben Swenson ,  Daniel Hendricks ,  Joe Fox ,  Terrece Pearman

发明人： David R. Hall ,  Conrad Rosenbrock ,  Ben Swenson ,  Daniel Hendricks ,  Joe Fox ,  Terrece Pearman

IPC分类号： G01N33/58 ,  G01N21/64 ,  A61B10/00 ,  E03D11/13 ,  E03D11/11 ,  G01N33/94 ,  G01N33/493

CPC分类号： G01N33/94 ,  A61B10/007 ,  E03D11/025 ,  E03D11/11 ,  E03D11/13 ,  G01N21/6428 ,  G01N21/645 ,  G01N33/493 ,  G01N2021/6417 ,  G01N2201/061

摘要： The present disclosure describes a toilet apparatus for detecting a drug marker in a urine sample. The drug markers are fluorophores each of which emits a unique fluorescence spectrum. Accordingly, the toilet does not detect the drug but rather, the drug marker. The user consumes a drug composition which includes a drug and a fluorescent drug marker. The user urinates normally into the toilet and fluorescence spectrometer within the toilet analyzes the urine for drug markers based on their unique fluorescent spectra. Computer software associated with the toilet identifies, and in some embodiments, quantifies the fluorescent spectra by comparing the detected spectra to known spectra of fluorescent markers associated with the drug.

公开(公告)号：US09671343B1

公开(公告)日：2017-06-06

申请号：US15361872

申请日：2016-11-28

申请人： David R. Hall ,  Conrad Rosenbrock ,  Ben Swenson ,  Dan Hendricks ,  Terrece Pearman

发明人： David R. Hall ,  Conrad Rosenbrock ,  Ben Swenson ,  Dan Hendricks ,  Terrece Pearman

IPC分类号： G01N21/64 ,  E03D11/11 ,  E03D11/13 ,  G01N33/493

CPC分类号： G01N21/6428 ,  E03D11/025 ,  E03D11/11 ,  E03D11/13 ,  G01N21/645 ,  G01N33/493 ,  G01N2021/6439

摘要： The present disclosure describes a method of detecting a drug marker in urine a urine sample using a toilet. The drug markers are fluorophores each of which emits a unique fluorescence spectra. Accordingly, the method does not detect the drug but rather, the drug marker. A user who has consumed the drug with its unique drug marker then urinates into the toilet and a urine sample is captured. The toilet includes a mechanism for fluid handling which diverts urine into a fluorescence spectrometer. The fluorescence spectrometer screens the urine for drug markers based on their unique fluorescent spectra. The toilet may include a controller which quantifies the drug marker. The fluorescent spectrometer may detect multiple drug markers in a single urine sample. This method may be used to confirm drug compliance, test for illicit drugs, identify amounts of drugs consumed, and other uses described herein.

公开(公告)号：US20200088714A1

公开(公告)日：2020-03-19

申请号：US16132918

申请日：2018-09-17

申请人： David R. Hall ,  Steven J.M. Butala ,  Estanislado Bravo ,  Joshua Larsen

发明人： David R. Hall ,  Steven J.M. Butala ,  Estanislado Bravo ,  Joshua Larsen

IPC分类号： G01N33/493 ,  G01N33/94 ,  G01N33/487

摘要： The method uses a device which measures the volatile organic compounds (VOCs) present in headspaces of fluid samples to differentiate between authentic and synthetic urine samples. The method includes the use of a device which includes an array of resistive microchemical sensors. The device may be exposed to samples of synthetic and authentic urine to identify a pattern of VOCs in each, these steps being referred to herein as training the device. The device may then be exposed to a urine sample of unknown authenticity and a pattern of VOCs identified. The pattern of VOCs from the urine sample of unknown authenticity may be compared to those of synthetic and authentic urine. In some embodiments the device is installed in a toilet. The method may be used to identify a false sample provided for a urine analysis intended to screen for use of illicit drugs.

公开(公告)号：US07766998B2

公开(公告)日：2010-08-03

申请号：US12016502

申请日：2008-01-18

申请人： David R. Hall ,  Tyson J. Wilde ,  Andrew Gerla ,  Joshua Larsen

发明人： David R. Hall ,  Tyson J. Wilde ,  Andrew Gerla ,  Joshua Larsen

IPC分类号： B01D53/02

CPC分类号： E03B3/28 ,  B01D5/0003 ,  B01D5/009 ,  B01D53/265 ,  F24T10/20 ,  Y02A20/109 ,  Y02E10/14

摘要： In one aspect of the present invention, an apparatus for the extraction of water from air incorporated into a wall of a building has a cavity formed in the wall. The cavity has an air inlet and an air outlet. A condensing surface is disposed within the cavity and is adapted to direct condensed water to a water storage unit. In another aspect of the present invention, the cavity is formed between two different building walls.

摘要翻译： 在本发明的一个方面，一种用于从结合到建筑物的壁中的空气中提取水的装置在壁中形成有空腔。 空腔具有空气入口和空气出口。 冷凝表面设置在空腔内并且适于将冷凝水引导到储水单元。 在本发明的另一方面，空腔形成在两个不同的建筑物墙壁之间。

公开(公告)号：US20090183631A1

公开(公告)日：2009-07-23

申请号：US12016502

申请日：2008-01-18

申请人： David R. Hall ,  Tyson J. Wilde ,  Andrew Gerla ,  Joshua Larsen

发明人： David R. Hall ,  Tyson J. Wilde ,  Andrew Gerla ,  Joshua Larsen

IPC分类号： B01D37/04 ,  B01D47/16

CPC分类号： E03B3/28 ,  B01D5/0003 ,  B01D5/009 ,  B01D53/265 ,  F24T10/20 ,  Y02A20/109 ,  Y02E10/14

摘要： In one aspect of the present invention, an apparatus for the extraction of water from air incorporated into a wall of a building has a cavity formed in the wall. The cavity has an air inlet and an air outlet. A condensing surface is disposed within the cavity and is adapted to direct condensed water to a water storage unit. In another aspect of the present invention, the cavity is formed between two different building walls.

摘要翻译： 在本发明的一个方面，一种用于从结合到建筑物的壁中的空气中提取水的装置在壁中形成有空腔。 空腔具有空气入口和空气出口。 冷凝表面设置在空腔内并且适于将冷凝水引导到储水单元。 在本发明的另一方面，空腔形成在两个不同的建筑物墙壁之间。

公开(公告)号：US11187695B2

公开(公告)日：2021-11-30

申请号：US16132918

申请日：2018-09-17

申请人： David R. Hall ,  Steven J. M. Butala ,  Estanislado Bravo ,  Joshua Larsen

发明人： David R. Hall ,  Steven J. M. Butala ,  Estanislado Bravo ,  Joshua Larsen

IPC分类号： G01N33/493 ,  G01N33/94 ,  G01N33/487

摘要： The method uses a device which measures the volatile organic compounds (VOCs) present in headspaces of fluid samples to differentiate between authentic and synthetic urine samples. The method includes the use of a device which includes an array of resistive microchemical sensors. The device may be exposed to samples of synthetic and authentic urine to identify a pattern of VOCs in each, these steps being referred to herein as training the device. The device may then be exposed to a urine sample of unknown authenticity and a pattern of VOCs identified. The pattern of VOCs from the urine sample of unknown authenticity may be compared to those of synthetic and authentic urine. In some embodiments the device is installed in a toilet. The method may be used to identify a false sample provided for a urine analysis intended to screen for use of illicit drugs.

公开(公告)号：US10241122B2

公开(公告)日：2019-03-26

申请号：US15472989

申请日：2017-03-29

申请人： David R. Hall ,  Steven Butala ,  Dan Allen ,  Daniel Hendricks ,  Andrew Nguyen ,  Conrad Rosenbrock ,  Terrece Pearman

发明人： David R. Hall ,  Steven Butala ,  Dan Allen ,  Daniel Hendricks ,  Andrew Nguyen ,  Conrad Rosenbrock ,  Terrece Pearman

IPC分类号： G01N33/58 ,  G01N33/94 ,  G01N33/493 ,  A61B5/00 ,  G01N21/64 ,  A61B10/00 ,  A61B5/145 ,  A61B5/1455 ,  A61B5/20

摘要： We disclose a drug tracking system and method of use which may be used to screen a subject's bodily waste in order to assess whether the subject has consumed a drug. The system includes a drug composition which is tagged with at least one artificial sweetener that may be detected in the subject's bodily waste. The subject may consume the tagged drug and a user may obtain a sample of the subject's bodily waste. The bodily waste sample may be analyzed to detect the artificial sweetener or its metabolite. In some embodiments, the result of the analysis of bodily waste may be entered into a database, compared to standards that comprises analyses of a plurality of drug tags, and the identity of the drug tag, and consequently the drug composition, determined.

公开(公告)号：US10203305B1

公开(公告)日：2019-02-12

申请号：US15659945

申请日：2017-07-26

申请人： David R. Hall ,  Dan Allen ,  Joe Fox

发明人： David R. Hall ,  Dan Allen ,  Joe Fox

IPC分类号： G01N27/62 ,  H01J49/00

摘要： The tandem differential mobility spectrometer (DMS)-ion modulator instrument provides improved resolution relative to traditional DMS for molecules with larger masses. The instrument includes multiple ion-bunching electrodes, each with an AC field synchronized to the transit time of the ion flow which is positioned downstream of a DMS. The ion bunching electrodes produce each a mobility-dependent modulation of the ion current. The ratio of AC to DC current provides a measure of the mobility of a large ion, even if it has little differential mobility, thereby extending the useful range of mobility characterization of a DMS system. The instrument does not require high voltages or high frequencies. Modulation before DMS separation or between tandem DMS separations produces a variable range of analyte and reactant ion densities as well as spatially separating negative and positive ions to reduce ion recombination.

公开(公告)号：US20180374693A1

公开(公告)日：2018-12-27

申请号：US15632636

申请日：2017-06-26

申请人： David R. Hall ,  Dan Allen ,  Joe Fox

发明人： David R. Hall ,  Dan Allen ,  Joe Fox

IPC分类号： H01J49/06 ,  H01J49/40 ,  H01J49/04 ,  G01N27/62

摘要： The tandem differential mobility spectrometer (DMS)-ion modulator instrument provides improved resolution relative to traditional DMS for molecules with larger masses. The instrument includes an ion-bunching electrode with an AC field synchronized to the transit time of the ion flow which is positioned downstream of a DMS. The ion bunching electrode produces a mobility-dependent modulation of the ion current. The ratio of AC to DC current provides a measure of the mobility of a large ion, even if it has little differential mobility, thereby extending the useful range of mobility characterization of a DMS system. The instrument is more compact than a larger traditional ion mobility spectrometer and does not require high voltages or high frequencies. Modulation before DMS separation or between tandem DMS separations produces a variable range of analyte and reactant ion densities as well as spatially separating negative and positive ions to reduce ion recombination.

公开(公告)号：US20180313805A1

公开(公告)日：2018-11-01

申请号：US15497501

申请日：2017-04-26

申请人： David R. Hall ,  Dan Allen ,  Conrad Rosenbrock ,  Daniel Hendricks ,  Andrew Nguyen ,  Steven J.M. Butala ,  Travis Niederhauser ,  Joe Fox ,  Terrece Pearman

发明人： David R. Hall ,  Dan Allen ,  Conrad Rosenbrock ,  Daniel Hendricks ,  Andrew Nguyen ,  Steven J.M. Butala ,  Travis Niederhauser ,  Joe Fox ,  Terrece Pearman

IPC分类号： G01N33/15 ,  G01N17/00

摘要： We disclose a method of using taggants to assess how and to what extent a drug in a drug composition has decayed in response to environmental conditions and time. The taggants may decay in response to environmental conditions which cause drugs to lose their efficacy. The decay may occur due to improper storage or excursions into certain environmental conditions. These environmental conditions may include light, temperature, moisture, oxidation, and age. By including taggants that have different decay characteristics, the environmental condition that caused the decay may be determined. The amount of time the drug composition was exposed to the environmental condition and the amount of effective drug remaining may also be determined. The disclosed method may reduce the need for a unique assay for each drug to assess decay and determine shelf life. The disclosed method may also be used as a quality control technique for pharmaceutical products.