公开(公告)号：US08636637B2

公开(公告)日：2014-01-28

申请号：US13571495

申请日：2012-08-10

申请人： Paul Lubock ,  Michael L. Jones ,  Frank R. Louw

发明人： Paul Lubock ,  Michael L. Jones ,  Frank R. Louw

IPC分类号： A61N5/00

CPC分类号： A61N5/1014 ,  A61N5/1002 ,  A61N5/1015 ,  A61N2005/1003 ,  A61N2005/1004 ,  A61N2005/1005 ,  A61N2005/1018 ,  A61N2005/1024

摘要： The disclosure describes devices and methods for asymmetrical irradiation at a body cavity or site, such as after removal of tissue, e.g. biopsy or cancer. One device includes a lumen which is off-set or off-settable from a longitudinal axis to increase the intensity of radiation received from a radiation source by a first tissue portion surrounding the body cavity and to reduce or minimize radiation received by a second tissue portion (e.g. healthy tissue) surrounding the body cavity.

摘要翻译： 本公开描述了用于在体腔或部位不对称照射的装置和方法，例如在去除组织之后，例如， 活检或癌症。 一个装置包括从纵向轴线偏移或不可固定的内腔，以增加围绕体腔的第一组织部分从辐射源接收的辐射的强度，并且减少或最小化由第二组织部分接收的辐射 （例如健康组织）。

公开(公告)号：US08251884B2

公开(公告)日：2012-08-28

申请号：US12151153

申请日：2008-05-02

申请人： Paul Lubock ,  Michael L. Jones ,  Frank R. Louw

发明人： Paul Lubock ,  Michael L. Jones ,  Frank R. Louw

IPC分类号： A61N5/00

CPC分类号： A61N5/1014 ,  A61N5/1002 ,  A61N5/1015 ,  A61N2005/1003 ,  A61N2005/1004 ,  A61N2005/1005 ,  A61N2005/1018 ,  A61N2005/1024

摘要： The disclosure describes devices and methods for asymmetrical irradiation at a body cavity or site, such as after removal of tissue, e.g. biopsy or cancer. One device includes a lumen which is off-set or off-settable from a longitudinal axis to increase the intensity of radiation received from a radiation source by a first tissue portion surrounding the body cavity and to reduce or minimize radiation received by a second tissue portion (e.g. healthy tissue) surrounding the body cavity.

公开(公告)号：US20080139928A1

公开(公告)日：2008-06-12

申请号：US11985997

申请日：2007-11-19

申请人： Paul Lubock ,  Michael L. Jones ,  Ethan Broadaway ,  Frank R. Louw

发明人： Paul Lubock ,  Michael L. Jones ,  Ethan Broadaway ,  Frank R. Louw

IPC分类号： A61B5/055 ,  A61B10/02

CPC分类号： A61B17/32 ,  A61B17/3417 ,  A61B17/3431 ,  A61B17/3468 ,  A61B17/3496 ,  A61B17/3498 ,  A61B90/39 ,  A61B2017/00477 ,  A61B2017/00911 ,  A61B2090/062 ,  A61B2090/3908 ,  A61B2090/3954 ,  A61B2090/3987

摘要： An obturator with an elongated shaft, a proximal end, a substantially closed distal end and a MRI detectable distal shaft portion, which does not interfere with magnetic resonance imaging of tissue proximate thereto. Preferably, the distal shaft portion has an effective MRI detectable mass so as to provide a clear, T1-weighted image within an outline of the distal shaft portion upon magnetic resonance imaging.

公开(公告)号：US20120310032A1

公开(公告)日：2012-12-06

申请号：US13571495

申请日：2012-08-10

申请人： Paul Lubock ,  Michael L. Jones ,  Frank R. Louw

发明人： Paul Lubock ,  Michael L. Jones ,  Frank R. Louw

IPC分类号： A61M36/12

CPC分类号： A61N5/1014 ,  A61N5/1002 ,  A61N5/1015 ,  A61N2005/1003 ,  A61N2005/1004 ,  A61N2005/1005 ,  A61N2005/1018 ,  A61N2005/1024

摘要： The disclosure describes devices and methods for asymmetrical irradiation at a body cavity or site, such as after removal of tissue, e.g. biopsy or cancer. One device includes a lumen which is off-set or off-settable from a longitudinal axis to increase the intensity of radiation received from a radiation source by a first tissue portion surrounding the body cavity and to reduce or minimize radiation received by a second tissue portion (e.g. healthy tissue) surrounding the body cavity.

摘要翻译： 本公开描述了用于在体腔或部位不对称照射的装置和方法，例如在去除组织之后，例如， 活检或癌症。 一个装置包括从纵向轴线偏移或不可固定的内腔，以增加围绕体腔的第一组织部分从辐射源接收的辐射的强度，并且减少或最小化由第二组织部分接收的辐射 （例如健康组织）。

公开(公告)号：US08326401B2

公开(公告)日：2012-12-04

申请号：US11985997

申请日：2007-11-19

申请人： Paul Lubock ,  Michael L. Jones ,  Ethan Broadaway ,  Frank R. Louw

发明人： Paul Lubock ,  Michael L. Jones ,  Ethan Broadaway ,  Frank R. Louw

IPC分类号： A61B5/05

CPC分类号： A61B17/32 ,  A61B17/3417 ,  A61B17/3431 ,  A61B17/3468 ,  A61B17/3496 ,  A61B17/3498 ,  A61B90/39 ,  A61B2017/00477 ,  A61B2017/00911 ,  A61B2090/062 ,  A61B2090/3908 ,  A61B2090/3954 ,  A61B2090/3987

摘要： An obturator with an elongated shaft, a proximal end, a substantially closed distal end and a MRI detectable distal shaft portion, which does not interfere with magnetic resonance imaging of tissue proximate thereto. Preferably, the distal shaft portion has an effective MRI detectable mass so as to provide a clear, T1-weighted image within an outline of the distal shaft portion upon magnetic resonance imaging.

摘要翻译： 具有细长轴，近端，基本上封闭的远端和MRI可检测远端轴部分的闭孔器，其不干扰邻近于其的组织的磁共振成像。 优选地，远侧轴部分具有有效的MRI检测质量，以便在磁共振成像时在远侧轴部分的轮廓内提供清晰的T1加权图像。

公开(公告)号：US20120071705A1

公开(公告)日：2012-03-22

申请号：US13302086

申请日：2011-11-22

申请人： Paul Lubock ,  Michael L. Jones ,  Frank R. Louw

发明人： Paul Lubock ,  Michael L. Jones ,  Frank R. Louw

IPC分类号： A61N5/00

CPC分类号： A61N5/1014 ,  A61N5/1002 ,  A61N5/1015 ,  A61N2005/1003 ,  A61N2005/1004 ,  A61N2005/1005 ,  A61N2005/1018 ,  A61N2005/1024

摘要： The disclosure describes devices and methods for asymmetrical irradiation at a body cavity or site, such as after removal of tissue, e.g. biopsy or cancer. One device includes a lumen which is off-set or off-settable from a longitudinal axis to increase the intensity of radiation received from a radiation source by a first tissue portion surrounding the body cavity and to reduce or minimize radiation received by a second tissue portion (e.g. healthy tissue) surrounding the body cavity.

摘要翻译： 本公开描述了用于在体腔或部位不对称照射的装置和方法，例如在去除组织之后，例如， 活检或癌症。 一个装置包括从纵向轴线偏移或不可固定的内腔，以增加围绕体腔的第一组织部分从辐射源接收的辐射的强度，并且减少或最小化由第二组织部分接收的辐射 （例如健康组织）。

公开(公告)号：US20080281142A1

公开(公告)日：2008-11-13

申请号：US12151153

申请日：2008-05-02

申请人： Paul Lubock ,  Michael L. Jones ,  Frank R. Louw

发明人： Paul Lubock ,  Michael L. Jones ,  Frank R. Louw

IPC分类号： A61N5/00

CPC分类号： A61N5/1014 ,  A61N5/1002 ,  A61N5/1015 ,  A61N2005/1003 ,  A61N2005/1004 ,  A61N2005/1005 ,  A61N2005/1018 ,  A61N2005/1024

摘要： The disclosure describes devices and methods for asymmetrical irradiation at a body cavity or site, such as after removal of tissue, e.g. biopsy or cancer. One device includes a lumen which is off-set or off-settable from a longitudinal axis to increase the intensity of radiation received from a radiation source by a first tissue portion surrounding the body cavity and to reduce or minimize radiation received by a second tissue portion (e.g. healthy tissue) surrounding the body cavity.

摘要翻译： 本公开描述了用于在体腔或部位不对称照射的装置和方法，例如在去除组织之后，例如， 活检或癌症。 一个装置包括从纵向轴线偏移或不可固定的内腔，以增加围绕体腔的第一组织部分从辐射源接收的辐射的强度，并且减少或最小化由第二组织部分接收的辐射 （例如健康组织）。

公开(公告)号：US09180312B2

公开(公告)日：2015-11-10

申请号：US13302086

申请日：2011-11-22

申请人： Paul Lubock ,  Michael L. Jones ,  Frank R. Louw

发明人： Paul Lubock ,  Michael L. Jones ,  Frank R. Louw

IPC分类号： A61N5/00 ,  A61N5/10

CPC分类号： A61N5/1014 ,  A61N5/1002 ,  A61N5/1015 ,  A61N2005/1003 ,  A61N2005/1004 ,  A61N2005/1005 ,  A61N2005/1018 ,  A61N2005/1024

摘要： The disclosure describes devices and methods for asymmetrical irradiation at a body cavity or site, such as after removal of tissue, e.g. biopsy or cancer. One device includes a lumen which is off-set or off-settable from a longitudinal axis to increase the intensity of radiation received from a radiation source by a first tissue portion surrounding the body cavity and to reduce or minimize radiation received by a second tissue portion (e.g. healthy tissue) surrounding the body cavity.

摘要翻译： 本公开描述了用于在体腔或部位不对称照射的装置和方法，例如在去除组织之后，例如， 活检或癌症。 一个装置包括从纵向轴线偏移或不可固定的内腔，以增加围绕体腔的第一组织部分从辐射源接收的辐射的强度，并且减少或最小化由第二组织部分接收的辐射 （例如健康组织）。

公开(公告)号：US08079946B2

公开(公告)日：2011-12-20

申请号：US11593784

申请日：2006-11-06

申请人： Paul Lubock ,  Michael L. Jones ,  Frank R. Louw

发明人： Paul Lubock ,  Michael L. Jones ,  Frank R. Louw

IPC分类号： A61N5/00

CPC分类号： A61N5/1014 ,  A61N5/1002 ,  A61N5/1015 ,  A61N2005/1003 ,  A61N2005/1004 ,  A61N2005/1005 ,  A61N2005/1018 ,  A61N2005/1024

摘要： The disclosure describes devices and methods for asymmetrical irradiation at a body cavity or site, such as after removal of tissue, e.g. biopsy or cancer. One device includes a lumen which is off-set or off-settable from a longitudinal axis to increase the intensity of radiation received from a radiation source by a first tissue portion surrounding the body cavity and to reduce or minimize radiation received by a second tissue portion (e.g. healthy tissue) surrounding the body cavity.

摘要翻译： 本公开描述了用于在体腔或部位不对称照射的装置和方法，例如在去除组织之后，例如， 活检或癌症。 一个装置包括从纵向轴线偏移或不可固定的内腔，以增加围绕体腔的第一组织部分从辐射源接收的辐射的强度，并且减少或最小化由第二组织部分接收的辐射 （例如健康组织）。

公开(公告)号：US20090124845A1

公开(公告)日：2009-05-14

申请号：US12290050

申请日：2008-10-27

申请人： Paul Lubock ,  Michael L. Jones ,  Frank R. Louw

发明人： Paul Lubock ,  Michael L. Jones ,  Frank R. Louw

IPC分类号： A61N5/00

CPC分类号： A61N5/1014 ,  A61N5/1002 ,  A61N5/1015 ,  A61N2005/1003 ,  A61N2005/1004 ,  A61N2005/1005 ,  A61N2005/1018 ,  A61N2005/1024

摘要： The disclosure describes devices and methods for asymmetrical irradiation at a body cavity or site, such as after removal of tissue, e.g. biopsy or cancer. One device includes a lumen which is off-set or off-settable from a longitudinal axis to increase the intensity of radiation received from a radiation source by a first tissue portion surrounding the body cavity and to reduce or minimize radiation received by a second tissue portion (e.g. healthy tissue) surrounding the body cavity.

摘要翻译： 本公开描述了用于在体腔或部位不对称照射的装置和方法，例如在去除组织之后，例如， 活检或癌症。 一个装置包括从纵向轴线偏移或不可固定的内腔，以增加围绕体腔的第一组织部分从辐射源接收的辐射的强度，并且减少或最小化由第二组织部分接收的辐射 （例如健康组织）。