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公开(公告)号:US20070048829A1
公开(公告)日:2007-03-01
申请号:US11550237
申请日:2006-10-17
申请人: Teresa Gilbert , Charles Hart , Paul Sheppard
发明人: Teresa Gilbert , Charles Hart , Paul Sheppard
IPC分类号: C12P21/06 , C07H21/04 , C07K14/475
CPC分类号: C04B38/06 , A61K38/177 , A61K38/18 , A61K38/1866 , A61K38/22 , C04B2111/00224 , C04B2111/00612 , C07K14/52 , C07K2319/00 , C12N2799/022 , C04B20/008 , C04B35/2641 , C04B35/50 , C04B35/64 , C04B38/0054 , C04B38/007 , C04B41/4578 , A61K2300/00
摘要: Polypeptide growth factors, methods of making them, polynucleotides encoding them, antibodies to them, and methods of using them are disclosed. The polypeptides comprise an amino acid segment that is at least 70% identical to residues 52-179 of SEQ ID NO:2 or residues 258-370 of SEQ ID NO:2. Multimers of the polypeptides are also disclosed. The polypeptides, multimeric proteins, and polynucleotides can be used in the study and regulation of cell and tissue development, as components of cell culture media, and as diagnostic agents.
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公开(公告)号:US20070043209A1
公开(公告)日:2007-02-22
申请号:US11548108
申请日:2006-10-10
申请人: Paul Sheppard , Scott Presnell , Brian Fox , Teresa Gilbert , Betty Haldeman , Francis Grant
发明人: Paul Sheppard , Scott Presnell , Brian Fox , Teresa Gilbert , Betty Haldeman , Francis Grant
IPC分类号: C07K16/24
CPC分类号: C07K14/47 , C07K14/52 , C07K2319/00
摘要: The present invention relates to polynucleotide and polypeptide molecules for Zcyto21, an interferon-like protein, which is most closely related to interferon-α at the amino acid sequence level. The present invention also includes antibodies to the Zcyto21 polypeptides, and methods of using the polynucleotides and polypeptides.
摘要翻译: 本发明涉及用于Zcyto21的多核苷酸和多肽分子,干扰素样蛋白与氨基酸序列水平上的干扰素-α最相关。 本发明还包括对Zcyto21多肽的抗体,以及使用多核苷酸和多肽的方法。
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公开(公告)号:US20060096611A1
公开(公告)日:2006-05-11
申请号:US10985100
申请日:2004-11-10
申请人: Nancy Leppla , Paul Sheppard , Roy Snider , Gerald Zinnbauer
发明人: Nancy Leppla , Paul Sheppard , Roy Snider , Gerald Zinnbauer
IPC分类号: A45D33/24
CPC分类号: A45D33/006
摘要: A cosmetic package is provided wherein the cover and container base are packaged in such a way as to allow a view of the product shade in the base at point of purchase.
摘要翻译: 提供了一种化妆品包装,其中盖子和容器底座以这样一种方式被包装,以便在购买点处允许在基部中的产品色调的视图。
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公开(公告)号:US20060040360A1
公开(公告)日:2006-02-23
申请号:US11258647
申请日:2005-10-25
IPC分类号: C07K14/705 , C07H21/04
CPC分类号: C07K14/47 , A61K38/00 , C07K2319/00 , C12N2799/026
摘要: The present invention relates to polynucleotide and polypeptide molecules for zacrp7, a novel member of the family of proteins bearing a collagen-like domain and a Clq domain. The polypeptides and polynucleotides encoding them, are involved in homo and heterotrimerization or oligomerization and may be used in the study thereof. The present invention also includes antibodies to the zacrp7 polypeptides.
摘要翻译: 本发明涉及用于zacrp7的多核苷酸和多肽分子,其是具有胶原样结构域和Clq结构域的蛋白家族的新成员。 编码它们的多肽和多核苷酸参与同源和异三聚或寡聚化,并可用于其研究。 本发明还包括针对zacrp7多肽的抗体。
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公开(公告)号:US20050214800A1
公开(公告)日:2005-09-29
申请号:US10982168
申请日:2004-11-05
申请人: Paul Sheppard , Paul Bishop
发明人: Paul Sheppard , Paul Bishop
CPC分类号: C07K14/52 , A61K38/00 , C07K14/4702 , C07K2319/00 , C12Q1/6888 , C12Q2600/158
摘要: The present invention provides two members of a new family of human proteins, designated as “Zven.” The Zven1 gene, which resides in human chromosome 3p21.1-3p14.3, is expressed in testicular tissue and peripheral blood lymphocytes.
摘要翻译: 本发明提供了两个称为“Zven”的人类蛋白质家族的成员。 位于人染色体3p21.1-3p14.3中的Zven1基因在睾丸组织和外周血淋巴细胞中表达。
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公开(公告)号:US20050214791A1
公开(公告)日:2005-09-29
申请号:US10970713
申请日:2004-10-20
申请人: Paul Sheppard , Scott Presnell
发明人: Paul Sheppard , Scott Presnell
CPC分类号: C07K14/52 , C07K14/47 , C07K2319/00
摘要: The present invention provides to polynucleotides and secreted proteins encoded by the polynucleotides. The proteins include a variety of fusion proteins, including fusions comprising a signal peptide selected from the group consisting of signal peptides shown in SEQ ID NO:M, wherein M is an even integer from 2 to 328, operably linked to a second polypeptide. The invention further provides therapeutic and diagnostic methods utilizing the polynucleotides, polypeptides, and antagonists of the polypeptides.
摘要翻译: 本发明提供了由多核苷酸编码的多核苷酸和分泌的蛋白质。 蛋白质包括多种融合蛋白,包括融合物,其包含选自SEQ ID NO:M所示的信号肽的信号肽,其中M为2至328的偶数整数,可操作地连接到第二多肽。 本发明还提供了利用多肽的多核苷酸,多肽和拮抗剂的治疗和诊断方法。
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公开(公告)号:US20050106680A1
公开(公告)日:2005-05-19
申请号:US10927891
申请日:2004-08-27
申请人: Paul Sheppard , Scott Presnell , Brian Fox , Teresa Gilbert , Betty Haldeman , Francis Grant
发明人: Paul Sheppard , Scott Presnell , Brian Fox , Teresa Gilbert , Betty Haldeman , Francis Grant
IPC分类号: G01N33/53 , C07H21/02 , C07H21/04 , C07K14/47 , C07K14/52 , C07K14/555 , C07K16/24 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/00 , C12N9/99 , C12N15/09 , C12N15/19 , C12N15/21 , C12N15/74 , C12P21/02 , C12P21/04 , C12P21/06 , C12Q1/68 , G01N33/566
CPC分类号: C07K14/47 , C07K14/52 , C07K2319/00
摘要: The present invention relates to polynucleotide and polypeptide molecules for Zcyto21, an interferon-like protein, which is most closely related to interferon-α at the amino acid sequence level. The present invention also includes antibodies to the Zcyto21 polypeptides, and methods of using the polynucleotides and polypeptides.
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