中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

215 records (took 0.034 seconds)

    COMBINATION
    91.
    发明申请
    COMBINATION 审中-公开

    公开(公告)号：US20130072507A1

    公开(公告)日：2013-03-21

    申请号：US13698847

    申请日：2011-05-19

    Applicant: Tona M. Gilmer ,  Rakesh Kumar

    Inventor： Tona M. Gilmer ,  Rakesh Kumar

    IPC: A61K31/517 ,  A61P35/02 ,  A61P35/00

    CPC classification number: A61K31/517 ,  A61K9/2018 ,  A61K9/2054 ,  A61K9/2059 ,  A61K9/4858 ,  A61K31/4155 ,  A61K31/4375 ,  A61K2300/00

    Abstract: The present invention relates to a method of treating cancer in a human and to pharmaceutical combinations useful in such treatment. In particular, the method relates to a cancer treatment method that includes administering N-{3-Chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methanesulphonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine, or a pharmaceutically acceptable hydrate and/or salt thereof, and N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecarboxamide, or a pharmaceutically acceptable salt thereof, to a human in need thereof.

    System and method for detection of multi-view/multi-pose objects
    93.
    发明授权
    System and method for detection of multi-view/multi-pose objects 有权
    用于检测多视点/多姿态对象的系统和方法

    公开(公告)号：US08391592B2

    公开(公告)日：2013-03-05

    申请号：US13134885

    申请日：2011-06-20

    Applicant: Feng Han ,  Ying Shan ,  Harpreet Singh Sawhney ,  Rakesh Kumar

    Inventor： Feng Han ,  Ying Shan ,  Harpreet Singh Sawhney ,  Rakesh Kumar

    IPC: G06K9/62

    CPC classification number: G06K9/6256

    Abstract: The present invention provides a computer implemented process for detecting multi-view multi-pose objects. The process comprises training of a classifier for each intra-class exemplar, training of a strong classifier and combining the individual exemplar-based classifiers with a single objective function. This function is optimized using the two nested AdaBoost loops. The first loop is the outer loop that selects discriminative candidate exemplars. The second loop, the inner loop selects the discriminative candidate features on the selected exemplars to compute all weak classifiers for a specific position such as a view/pose. Then all the computed weak classifiers are automatically combined into a final classifier (strong classifier) which is the object to be detected.

    Abstract translation: 本发明提供了一种用于检测多视点多姿态对象的计算机实现过程。 该过程包括针对每个类内样本的分类器的训练，强分类器的训练和将单个基于样本的分类器与单个目标函数组合。 使用两个嵌套的AdaBoost循环来优化此功能。 第一个循环是选择区分候选样本的外循环。 第二个循环，内循环选择所选样本上的鉴别候选特征，以计算特定位置（例如视图/姿态）的所有弱分类器。 然后将所有计算的弱分类器自动组合成最终分类器（强分类器），该分类器是要检测的对象。

    Managing Power Consumption In A Multi-Core Processor
    95.
    发明申请
    Managing Power Consumption In A Multi-Core Processor 有权
    管理多核处理器中的功耗

    公开(公告)号：US20120254643A1

    公开(公告)日：2012-10-04

    申请号：US13422476

    申请日：2012-03-16

    Applicant: Eric Fetzer ,  Reid J. Reidlinger ,  Don Soltis ,  William J. Bowhill ,  Satish Shrimali ,  Krishnakanth Sistla ,  Efraim Rotem ,  Rakesh Kumar ,  Vivek Garg ,  Alon Naveh ,  Lokesh Sharma

    Inventor： Eric Fetzer ,  Reid J. Reidlinger ,  Don Soltis ,  William J. Bowhill ,  Satish Shrimali ,  Krishnakanth Sistla ,  Efraim Rotem ,  Rakesh Kumar ,  Vivek Garg ,  Alon Naveh ,  Lokesh Sharma

    IPC: G06F1/32

    CPC classification number: G06F1/3296 ,  G06F1/324 ,  Y02D10/126 ,  Y02D10/172 ,  Y02D50/20

    Abstract: A processor may include a core and an uncore area. The power consumed by the core area may be controlled by controlling the Cdyn of the processor such that the Cdyn is within an allowable Cdyn value irrespective of the application being processed by the core area. The power management technique includes measuring digital activity factor (DAF), monitoring architectural and data activity levels, and controlling power consumption by throttling the instructions based on the activity levels. As a result of throttling the instructions, throttling may be implemented in 3rd droop and thermal design point (TDP). Also, the idle power consumed by the uncore area while the core area is in deep power saving states may be reduced by varying the reference voltage VR and the VP provided to the uncore area. As a result, the idle power consumed by the uncore area may be reduced.

    Abstract translation: 处理器可以包括核心和无孔区域。 可以通过控制处理器的Cdyn来控制核心区域消耗的功率，使得Cdyn处于可允许的Cdyn值内，而不管应用程序是否被核心区域处理。 电源管理技术包括测量数字活动因素（DAF），监控架构和数据活动级别，以及通过基于活动级别来限制指令来控制功耗。 作为节流指令的结果，节流可以在第3垂直和热设计点（TDP）中实现。 此外，通过改变提供给无孔区域的参考电压VR和VP，可以减少核心区域处于深功率节省状态时由无孔区域消耗的空闲功率。 结果，可以减少由无孔区域消耗的空闲功率。

    Pharmaceutical Combination of MEK Inhibitor and B-RAF Inhibitors
    96.
    发明申请
    Pharmaceutical Combination of MEK Inhibitor and B-RAF Inhibitors 有权
    MEK抑制剂和B-RAF抑制剂的药物组合

    公开(公告)号：US20120196879A1

    公开(公告)日：2012-08-02

    申请号：US13499779

    申请日：2010-10-15

    Applicant: Melissa Dumble ,  Rakesh Kumar ,  Sylvie Laquerre ,  Peter Lebowitz

    Inventor： Melissa Dumble ,  Rakesh Kumar ,  Sylvie Laquerre ,  Peter Lebowitz

    IPC: A61K31/519 ,  A61P35/02 ,  A61P35/00

    CPC classification number: A61K31/519 ,  A61K31/506 ,  A61K45/06 ,  A61K2300/00

    Abstract: A novel combination comprising the MEK inhibitor N-{3-[3-cyclopropyl-5-(2-fluoro-4-iodo-phenylamino)6,8-dimethyl;-2,4,7-trioxo-3,4,6,7-tetrahydro-2H-pyrido[4,3-d]pyrimidin-1-yl]phenyl}acetamide, or a pharmaceutically acceptable salt or solvate thereof, with a B-Raf inhibitor, particularly N-{3-[5-(2-Amino-4-pyrimidinyl)-2-(1,1-dimethylethyl)-1,3-thiazol-4-yl]-2-fluorophen-}-2,6-difluorobenzenesulfonamide or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising the same and methods of using such combinations and compositions in the treatment of conditions in which the inhibition of MEK and/or B-Raf is beneficial, eg. cancer.

    Abstract translation: 包含MEK抑制剂N- {3- [3-环丙基-5-（2-氟-4-碘 - 苯基氨基）6,8-二甲基-2,4,7-三氧代-3,4,6 ，7-四氢-2H-吡啶并[4,3-d]嘧啶-1-基]苯基}乙酰胺或其药学上可接受的盐或溶剂合物与B-Raf抑制剂，特别是N- {3- [5- （2-氨基-4-嘧啶基）-2-（1,1-二甲基乙基）-1,3-噻唑-4-基] -2-氟苯基} -2,6-二氟苯磺酰胺或其药学上可接受的盐，药物 包含其的组合物和使用这些组合和组合物治疗MEK和/或B-Raf的抑制作用有利的条件的方法，例如， 癌症。

    Building segmentation for densely built urban regions using aerial LIDAR data
    98.
    发明授权
    Building segmentation for densely built urban regions using aerial LIDAR data 有权
    使用航空LIDAR数据建造高密度城市地区的分段

    公开(公告)号：US08224097B2

    公开(公告)日：2012-07-17

    申请号：US12138027

    申请日：2008-06-12

    Applicant: Bogdan Calin Mihai Matei ,  Supun Samarasekera ,  Janet Yonga Kim ,  Charles Fielding Finch Karney ,  Harpreet Singh Sawhney ,  Rakesh Kumar

    Inventor： Bogdan Calin Mihai Matei ,  Supun Samarasekera ,  Janet Yonga Kim ,  Charles Fielding Finch Karney ,  Harpreet Singh Sawhney ,  Rakesh Kumar

    IPC: G06K9/46 ,  G06K9/34

    CPC classification number: G06T7/11 ,  G06T2207/10032 ,  G06T2207/30184

    Abstract: A method for extracting a 3D terrain model for identifying at least buildings and terrain from LIDAR data is disclosed, comprising the steps of generating a point cloud representing terrain and buildings mapped by LIDAR; classifying points in the point cloud, the point cloud having ground and non-ground points, the non-ground points representing buildings and clutter; segmenting the non-ground points into buildings and clutter; and calculating a fit between at least one building segment and at least one rectilinear structure, wherein the fit yields the rectilinear structure with the fewest number of vertices. The step of calculating further comprises the steps of (a) calculating a fit of a rectilinear structure to the at least one building segment, wherein each of the vertices has an angle that is a multiple of 90 degrees; (b) counting the number of vertices; (c) rotating the at least one building segment about an axis by a predetermined increment; and (d) repeating steps (a)-(c) until a rectilinear structure with the least number of vertices is found.

    Abstract translation: 公开了一种用于从LIDAR数据中提取用于识别至少建筑物和地形的3D地形模型的方法，包括以下步骤：生成表示由LIDAR映射的地形和建筑物的点云; 点云分点，点云具有地面和非地面点，代表建筑物的非地面点和杂乱; 将非地面点划分为建筑物和混乱; 以及计算至少一个构建段和至少一个直线结构之间的拟合，其中所述拟合产生具有最少数量顶点的直线结构。 计算步骤还包括以下步骤：（a）计算直线结构对至少一个构建段的拟合，其中每个顶点具有90度的倍数的角度; （b）计算顶点数; （c）使所述至少一个构建段绕轴线旋转预定的增量; 和（d）重复步骤（a） - （c），直到找到具有最少顶点数的直线结构。

    Low noise amplifier circuit
    99.
    发明授权
    Low noise amplifier circuit 有权
    低噪声放大器电路

    公开(公告)号：US08217723B2

    公开(公告)日：2012-07-10

    申请号：US12612691

    申请日：2009-11-05

    Applicant: Gireesh Rajendran ,  Ashish Lachhwani ,  Rakesh Kumar

    Inventor： Gireesh Rajendran ,  Ashish Lachhwani ,  Rakesh Kumar

    IPC: H03F1/22

    CPC classification number: H03G1/007 ,  H03F1/223 ,  H03F3/191 ,  H03F2200/294

    Abstract: Low noise amplifier circuit. The low noise amplifier circuit includes an amplifier that amplifies an input to provide an output. The amplifier is coupled to an input terminal. The circuit also includes a device in a cascode connection with the amplifier. The circuit further includes a tuning circuit coupled to the device to phase shift the output. Further, the circuit includes a feedback circuit that is responsive to a phase-shifted output to enhance gain of the amplifier. The feedback circuit is coupled to the tuning circuit and the amplifier.

    Abstract translation: 低噪声放大器电路。 低噪声放大器电路包括放大输入以提供输出的放大器。 放大器耦合到输入端。 该电路还包括与放大器的共源共栅连接的装置。 该电路还包括耦合到该器件以相移输出的调谐电路。 此外，电路包括响应于相移输出以增强放大器增益的反馈电路。 反馈电路耦合到调谐电路和放大器。

    MICROWAVE INDUCED SINGLE STEP GREEN SYNTHESIS OF SOME NOVEL 2-ARYL ALDEHYDES AND THEIR ANALOGUES
    100.
    发明申请
    MICROWAVE INDUCED SINGLE STEP GREEN SYNTHESIS OF SOME NOVEL 2-ARYL ALDEHYDES AND THEIR ANALOGUES 失效
    微波诱导的单步绿色合成一些新型二芳基醛及其类似物

    公开(公告)号：US20120041234A1

    公开(公告)日：2012-02-16

    申请号：US13203100

    申请日：2010-02-25

    Applicant: Arun Kumar Sinha ,  Abhishek Sharma ,  Rakesh Kumar ,  Naina Sharma

    Inventor： Arun Kumar Sinha ,  Abhishek Sharma ,  Rakesh Kumar ,  Naina Sharma

    IPC: C07C251/80 ,  C07C45/00 ,  B01J19/12 ,  C07C47/27

    CPC classification number: C07C45/28 ,  C07C45/30 ,  C07C249/16 ,  C07C311/49 ,  C07D317/54 ,  C07C47/228 ,  C07C47/24 ,  C07C47/23 ,  C07C47/277

    Abstract: The present invention provides a process for the preparation of some novel 2-aryl and 2,2-diaryl aldehydes and analogues which are privileged intermediates for commercially important nonsteroidal anti-inflammatory drugs including naproxen, flurbiprofen and potent anticancer drug candidates, including phenstatin through a unique single step synthetic methodology utilizing easily available substrates in the form of aryl alkenes as well as environmentally benign aqueous reaction conditions in the form of solvents such as mixtures of water and DMSO or Dioxane and reagents N-bromosuccinimide, N-iodosuccinimide, N-cholorosuccinimide and phase transfer catalyst such as cetyltrimethyl ammonium bromide, N-hexyl ammonium chloride for a reaction time varying from 1 min-30 min, depending upon microwave or conventional heating, without using expensive transition metal catalysts or lewis acids/bases with yield varying from 35-55%, depending upon the solvent and substrate used. The developed method provides a clean and convenient alternative to access a diverse range of medicinally important 2-aryl and 2,2-diaryl aldehyde based scaffolds in lieu of the conventional multistep protocols employing expensive and hazardous transition metal catalysts and lewis acids/bases.

    Abstract translation: 本发明提供了一种制备一些新的2-芳基和2,2-二芳基醛和类似物的方法，其是用于商业上重要的非甾族抗炎药物的特权中间体，包括萘普生，氟比洛芬和有效的抗癌药物候选物，包括通过 使用易于获得的芳基烯烃底物的独特的单步合成方法以及溶剂形式的环境友好的水性反应条件，例如水和DMSO或二恶烷的混合物以及试剂N-溴琥珀酰亚胺，N-碘代琥珀酰亚胺，N-氯代氯代琥珀酰亚胺 和相转移催化剂如十六烷基三甲基溴化铵，N-己基氯化铵，反应时间为1分钟-30分钟，取决于微波或常规加热，不使用昂贵的过渡金属催化剂或路易斯酸/碱，产率从35 -55％，这取决于所用的溶剂和底物。 开发的方法提供了一种干净和方便的替代方案，以便获得各种各样的药物重要的2-芳基和2,2-二芳基醛基支架，代替常规的多步骤方案，其采用昂贵且危险的过渡金属催化剂和路易斯酸/碱。

Patent Agency Ranking