公开(公告)号：US20100004438A1

公开(公告)日：2010-01-07

申请号：US12095930

申请日：2006-12-04

Applicant: Hironori Matsuyama ,  Kenji Ohnishi ,  Takashi Nakagawa ,  Hideki Takasu ,  Makoto Sakamoto ,  Kumi Higuchi ,  Keisuke Miyajima ,  Satoshi Yamada ,  Masaaki Motoyama ,  Yutaka Kojima ,  Koichi Yasumura ,  Takeshi Kodama ,  Shun Otsuji ,  Keizo Kan ,  Takumi Sumida

Inventor： Hironori Matsuyama ,  Kenji Ohnishi ,  Takashi Nakagawa ,  Hideki Takasu ,  Makoto Sakamoto ,  Kumi Higuchi ,  Keisuke Miyajima ,  Satoshi Yamada ,  Masaaki Motoyama ,  Yutaka Kojima ,  Koichi Yasumura ,  Takeshi Kodama ,  Shun Otsuji ,  Keizo Kan ,  Takumi Sumida

IPC: C07D401/14 ,  C07D405/14 ,  C07D413/14 ,  C07D401/12 ,  C07D295/155 ,  C07D211/56 ,  C07D213/72

CPC classification number: A61K31/496 ,  A61K31/495

Abstract: An object of the present invention is to provide a medicinal drug much improved in anti tumor activity and excellent in safety. According to the present invention, there is provided a medicinal drug containing a compound represented by the following general formula (1) or a salt thereof as an active ingredient: [Formula 1] wherein X1 represents a nitrogen atom or a group —CH═, R1 represents a group -Z-R6, in which Z represents a group —CO—, a group —CH(OH)— or the like, R6 represents a 5- to 15-membered monocyclic, dicyclic or tricyclic saturated or unsaturated heterocyclic group having 1 to 4 nitrogen atoms, oxygen atoms or sulfur atoms, R2 represents a hydrogen atom or a halogen atom, Y represents a group —O—, a group —CO—, a group —CH(OH)— or a lower alkylene group, and A represents [Formula 2] wherein R3 represents a hydrogen atom, a lower alkoxy group or the like, p represents 1 or 2, R4 represents an imidazolyl lower alkyl group or the like.

Abstract translation: 本发明的目的在于提供一种抗肿瘤活性大大提高的安全性药物。 根据本发明，提供含有下述通式（1）表示的化合物或其盐作为有效成分的药物：[式1]其中X1表示氮原子或基团-CH-， R1表示基团-Z-R6，其中Z表示基团-CO-，基团-CH（OH） - 等，R6表示5至15元单环，二环或三环饱和或不饱和杂环基 具有1至4个氮原子，氧原子或硫原子，R 2表示氢原子或卤素原子，Y表示基团-O-，基团-CO-，基团-CH（OH） - 或低级亚烷基 A表示[式2]其中R3表示氢原子，低级烷氧基等，p表示1或2，R4表示咪唑基低级烷基等。

公开(公告)号：US07475929B2

公开(公告)日：2009-01-13

申请号：US11189014

申请日：2005-07-26

Applicant: Satoshi Yamada

Inventor： Satoshi Yamada

IPC: B60R27/00

CPC classification number: E05B63/248 ,  E05B1/0038 ,  E05B83/30 ,  E05C9/04 ,  E05C9/185 ,  Y10T70/5093

Abstract: A lid open-close apparatus including: a lid openably mounted in a concave portion, which is provides at a vehicle side; a lock device for locking a closed state of the lid; and an operating element, which is disposed at the vehicle side close to the concave portion, for releasing the lock device, wherein: the lock device has a lock piece, which is provided in the lid and moves into and out of the lid from a peripheral edge thereof and is usually elastically pushed in such a way as to project from the peripheral edge thereof and engages with an engaging hole provided in an inner periphery of the concave portion; and the operating element has a pusher adapted to push a receiving portion, which is provided in a part interconnected to the lock piece, to thereby cancel engagement of the lock piece.

Abstract translation: 一种盖开闭装置，包括：可开启地安装在车辆侧的凹部的盖子; 用于锁定盖的关闭状态的锁定装置; 以及操作元件，其设置在靠近所述凹部的所述车辆侧，用于释放所述锁定装置，其中：所述锁定装置具有锁定件，所述锁定件设置在所述盖中并且从所述盖子移入和移出所述盖子 并且通常弹性推动其从其周边突出，并与设置在凹部的内周中的接合孔接合; 并且操作元件具有推动器，其适于推动设置在与锁定件互连的部分中的接收部分，从而消除锁定件的接合。

公开(公告)号：US20080304983A1

公开(公告)日：2008-12-11

申请号：US12109584

申请日：2008-04-25

Applicant: Satoshi Yamada ,  Hitoshi Onishi

Inventor： Satoshi Yamada ,  Hitoshi Onishi

IPC: F04B43/04

CPC classification number: F04B43/02 ,  F04B43/04

Abstract: A diaphragm air pump includes a diaphragm; and upper and lower housings that interpose the diaphragm such that a variable volume chamber is formed over and under the diaphragm. The diaphragm air pump vibrates the diaphragm to obtain a pump operation, a circular concave portion into which the diaphragm that is circular in plan view is fitted is formed in any one of the upper and lower housings, a ring-shaped groove for housing a seal member is formed in the other, the ring-shaped groove having inner and outer diameters which are set across the circular concave portion, and a ring-shaped elastic seal member which is compressively deformed across the periphery of the diaphragm by the upper and lower housings is housed in the ring-shaped groove.

Abstract translation: 隔膜气泵包括隔膜; 以及插入隔膜的上下壳体，使得在隔膜上方和下方形成可变容积室。 隔膜空气泵振动隔膜以获得泵操作，在上壳体和下壳体中的任一个中形成有在平面图中安装有圆形的隔膜的圆形凹部，用于容纳密封件的环形槽 另一方面形成有形成有贯穿圆形凹部的内径和外径的环状槽，以及环状的弹性密封部件，其通过上下壳体在隔膜的周缘上压缩变形 容纳在环形槽中。

公开(公告)号：US07383707B2

公开(公告)日：2008-06-10

申请号：US10850556

申请日：2004-05-21

Applicant: Satoshi Yamada ,  Toshihiro Shimizu

Inventor： Satoshi Yamada ,  Toshihiro Shimizu

IPC: E05B13/00

CPC classification number: E05B83/30 ,  E05B85/18 ,  Y10S292/27 ,  Y10S292/31 ,  Y10S292/63 ,  Y10T70/5416 ,  Y10T70/5496 ,  Y10T70/5761 ,  Y10T70/5805 ,  Y10T292/0886 ,  Y10T292/0974 ,  Y10T292/57

Abstract: An storage locking apparatus including a case attached to an end edge of the storage, a locking member slidably supported by the case for engaging with and disengaging from the supporting member, a first urging member for always urging the locking member in a direction of the supporting member, an operating handle pivotably supported axially by the case for unlocking the storage by being pivoted from a side of the supporting member to a side of the storage, and lever mechanisms for sliding the locking member against the first urging member by pivoting the operating handle in which the supporting member dispenses with a containing portion in a recessed shape as in a prior art by providing an operating space between the supporting member and the operating handle.

Abstract translation: 一种存储锁定装置，包括附接到所述存储器的端边缘的壳体，由所述壳体可滑动地支撑以与所述支撑构件接合和脱离接合的锁定构件;用于总是沿所述支撑件的方向推动所述锁定构件的第一施力构件 构件，操作手柄，其可旋转地由所述壳体轴向地支撑，以通过从所述支撑构件的侧面枢转到所述存储器的侧面来解锁所述存储器;以及杠杆机构，用于通过枢转所述操作手柄来将所述锁定构件滑动抵靠所述第一推动构件 其中通过在支撑构件和操作手柄之间提供操作空间，支撑构件如现有技术那样分配凹陷形状的容纳部分。

公开(公告)号：US07295227B1

公开(公告)日：2007-11-13

申请号：US09484316

申请日：2000-01-18

Applicant: Goro Asahi ,  Hisashi Kuriya ,  Masashi Ushino ,  Tomio Kimura ,  Kousuke Teramura ,  Kazunori Shimazaki ,  Kanji Hattori ,  Satoshi Yamada

Inventor： Goro Asahi ,  Hisashi Kuriya ,  Masashi Ushino ,  Tomio Kimura ,  Kousuke Teramura ,  Kazunori Shimazaki ,  Kanji Hattori ,  Satoshi Yamada

IPC: H04N7/00 ,  H04N7/18

CPC classification number: G01S15/931 ,  B60R1/00 ,  B60R2300/301 ,  B60R2300/302 ,  B60R2300/305 ,  B60R2300/806 ,  B60R2300/8093 ,  B62D15/0275 ,  B62D15/028 ,  G01S15/025 ,  G01S2015/935 ,  H04N7/183

Abstract: A steering assist apparatus that assists a driver when backing a vehicle in an S-shaped path or parallel parking. The apparatus displays guidance marking on a monitor screen and the driver refers to the guidance marking, which permits the driver to easily back the vehicle to a desired position. The apparatus includes a camera, a monitor, an angle sensor, obstacle sensors, an image processing unit, a controller and a monitor controller. The image processing unit computes the predicted path of the vehicle at the current wheel angle. The monitor shows an image captured by the camera. The image processing unit generates data representing a guidance marking based on the predicted path and superimposes the marking on the monitor screen. The location of the marking on the screen is determined based on the current wheel angle. The marking represents part of the predicted path. Specifically, the marking matches the width of the vehicle. In the monitor screen, a marking is separated from the rear bumper of the vehicle by a distance corresponding to the wheelbase of the vehicle.

Abstract translation: 一种辅助驾驶员在将车辆背置在S形路径或平行停车场时的转向辅助装置。 该装置在监视器屏幕上显示引导标记，并且驾驶员参考引导标记，其允许驾驶员容易地将车辆返回到期望的位置。 该装置包括照相机，监视器，角度传感器，障碍传感器，图像处理单元，控制器和监视器控制器。 图像处理单元以当前车轮角度计算车辆的预测路径。 显示器显示相机拍摄的图像。 图像处理单元基于预测路径产生表示引导标记的数据，并将标记叠加在监视器屏幕上。 基于当前车轮角度确定屏幕上的标记位置。 标记代表预测路径的一部分。 具体地，该标记与车辆的宽度相匹配。 在监视器屏幕中，标记与车辆的后保险杠分开与车辆的轴距相对应的距离。

公开(公告)号：US20060181065A1

公开(公告)日：2006-08-17

申请号：US11339514

申请日：2006-01-26

Applicant: Satoshi Yamada ,  Kouitirou Uezono ,  Masatoshi Ishigaki ,  Ryuji Sagisaka

Inventor： Satoshi Yamada ,  Kouitirou Uezono ,  Masatoshi Ishigaki ,  Ryuji Sagisaka

IPC: B60R21/215

CPC classification number: B60R21/2165 ,  B60R2021/21537

Abstract: An airbag apparatus comprised of a cover for covering an expanding side of an airbag and forming an opening for the airbag. The cover is comprised of a door portion disposed at the expanding side of the airbag, a surrounding portion surrounding the door portion, a tear portion defining the door portion and tearing due to an expansion force of the airbag, an installation portion protruding from the surrounding portion adjacent to the tear portion toward an opposite side of the expanding side, and a hinge portion connecting the door portion and the surrounding portion located outside of the installation portion.

Abstract translation: 一种气囊装置，包括用于覆盖气囊的扩张侧的盖，并形成用于所述气囊的开口。 所述盖由设置在所述气囊的膨胀侧的门部，围绕所述门部的周围部分，限定所述门部的撕裂部和由于所述气囊的膨胀力而导致的撕裂;从周围突出的安装部 靠近所述撕裂部的部分朝向所述扩张侧的相反侧;以及铰链部，其连接所述门部和位于所述安装部外侧的周围部。

公开(公告)号：US20060173088A1

公开(公告)日：2006-08-03

申请号：US10564052

申请日：2004-07-16

Applicant: Shigeyuki Nozaki ,  Daisuke Imai ,  Satoshi Yamada ,  Shuichi Toriya ,  Hidekazu Kozuki ,  Masaru Ishikawa

Inventor： Shigeyuki Nozaki ,  Daisuke Imai ,  Satoshi Yamada ,  Shuichi Toriya ,  Hidekazu Kozuki ,  Masaru Ishikawa

IPC: C08J9/00

CPC classification number: C08J9/30 ,  C08F2/10

Abstract: A method for efficient production of a water-soluble porous polymer and a water-soluble porous polymer excelling in solubility in water are provided. A method for the production of the polymer is characterized by the fact that an aqueous monomer solution containing an ethylenically unsaturated monomer is polymerized while it is containing bubbles therein. The method can simplify the drying and crushing steps and the water-soluble porous polymer consequently obtained excels in solubility in water.

Abstract translation: 提供了一种有效生产水溶性多孔聚合物和在水中溶解度优异的水溶性多孔聚合物的方法。 聚合物的制造方法的特征在于，含有烯属不饱和单体的单体水溶液在其内含有气泡的同时聚合。 该方法可以简化干燥和粉碎步骤，因此得到的水溶性多孔聚合物在水中的溶解度优异。

公开(公告)号：USD525547S1

公开(公告)日：2006-07-25

申请号：US29223907

申请日：2005-02-23

Applicant: Satoshi Yamada ,  Tameo Ashida ,  Jiazheng Jin ,  Takashi Shigeno ,  Yoshio Kusumi

Designer： Satoshi Yamada ,  Tameo Ashida ,  Jiazheng Jin ,  Takashi Shigeno ,  Yoshio Kusumi

公开(公告)号：US20060055196A1

公开(公告)日：2006-03-16

申请号：US11189014

申请日：2005-07-26

Applicant: Satoshi Yamada

Inventor： Satoshi Yamada

IPC: B60R7/06

CPC classification number: E05B63/248 ,  E05B1/0038 ,  E05B83/30 ,  E05C9/04 ,  E05C9/185 ,  Y10T70/5093

Abstract: A lid open-close apparatus including: a lid openably mounted in a concave portion, which is provides at a vehicle side; a lock device for locking a closed state of the lid; and an operating element, which is disposed at the vehicle side close to the concave portion, for releasing the lock device, wherein: the lock device has a lock piece, which is provided in the lid and moves into and out of the lid from a peripheral edge thereof and is usually elastically pushed in such a way as to project from the peripheral edge thereof and engages with an engaging hole provided in an inner periphery of the concave portion; and the operating element has a pusher adapted to push a receiving portion, which is provided in a part interconnected to the lock piece, to thereby cancel engagement of the lock piece.

公开(公告)号：US06694199B1

公开(公告)日：2004-02-17

申请号：US09701378

申请日：2000-11-30

Applicant: Satoshi Yamada ,  Masanobu Ishii ,  Yoshito Inoichi

Inventor： Satoshi Yamada ,  Masanobu Ishii ,  Yoshito Inoichi

IPC: G05B1942

CPC classification number: G06T19/00 ,  G06T17/10

Abstract: An automatic programming apparatus wherein respective planes constituting a solid input from a two-dimensional three-side view drawing are displayed on a screen. When a reference plane and a butting plane are specified within the respective planes, a temporary development diagram is generated in which the butting plane is butted to the reference plane. A solid figure is generated by bending the temporary development diagram based on a bending condition and displayed interlockingly in a region different from a region where the temporary development diagram is displayed. A development diagram obtained by extracting external frame loop and bending lines of the temporary development diagram is transmitted to CAM on a preceding stage.

Abstract translation: 一种自动编程设备，其中从屏幕上显示从二维三视图构成固体输入的各个平面。 当在相应的平面内指定参考平面和对接平面时，产生临时显影图，其中对接平面对准参考平面。 通过基于弯曲条件弯曲临时展开图并且在与显示临时展示图的区域不同的区域中互锁地显示实体图。 通过提取临时开发图的外部帧循环和弯曲线而获得的开发图在前一阶段被发送到CAM。