公开(公告)号：US20100286573A1

公开(公告)日：2010-11-11

申请号：US12681539

申请日：2008-10-03

Applicant: Karl H. Schoenbach

Inventor： Karl H. Schoenbach

IPC: A61N7/02

CPC classification number: A61B18/18 ,  A61B18/1815 ,  A61N5/02 ,  A61N5/025

Abstract: A method of inducing local hyperthermia in patient tissue is provided. The method includes generating ultra-wide-band radiation, conveying the ultra-wideband radiation to a focusing element, and focusing the ultra-wideband radiation on a target with the focusing element. A system for inducing local hyperthermia in patient tissue is also provided. The system includes a power source for generating ultra-wideband radiation, and a focusing element for focusing the ultra-wideband radiation on a target.

Abstract translation: 提供了一种诱导患者组织局部热疗的方法。 该方法包括产生超宽带辐射，将超宽带辐射传送到聚焦元件，以及将超宽带辐射与聚焦元件聚焦在目标上。 还提供了用于诱导患者组织中局部热疗的系统。 该系统包括用于产生超宽带辐射的电源和用于将超宽带辐射聚焦在目标上的聚焦元件。

公开(公告)号：US20100278401A1

公开(公告)日：2010-11-04

申请号：US12809007

申请日：2008-12-19

Applicant: Karl H. Schoenbach ,  Shu Xiao

Inventor： Karl H. Schoenbach ,  Shu Xiao

IPC: G06T7/00

CPC classification number: A61B5/0507 ,  A61B5/05 ,  A61B6/03 ,  A61B2576/00

Abstract: An imaging and recordation system is provided. The system includes a high-power, focusing antenna for illuminating biological tissue. The system further includes a power source for powering the antenna. The system further includes a data acquisition module, for recording the dielectric properties of tissues illuminated by the high-power, focusing antenna. The system illuminates the tissues using ultrashort electrical pulses.

Abstract translation: 提供成像和记录系统。 该系统包括用于照射生物组织的大功率聚焦天线。 该系统还包括用于为天线供电的电源。 该系统还包括数据采集模块，用于记录由大功率聚焦天线照射的组织的介电特性。 系统使用超短电脉冲照射组织。

公开(公告)号：US20100211331A1

公开(公告)日：2010-08-19

申请号：US12707233

申请日：2010-02-17

Applicant: Sebastian Bawab ,  Stacie Ringleb ,  Manish G. Kalmegh

Inventor： Sebastian Bawab ,  Stacie Ringleb ,  Manish G. Kalmegh

IPC: G01L5/00 ,  G01B5/14

CPC classification number: G01B21/047 ,  G01L5/16 ,  G01M5/005

Abstract: A system for measuring normal load and deflection of a material that includes a portable load deflection device and a method of using the same is disclosed. The system includes a support arm having a first end and a second end opposite said first end. The first end can be attached to a base surface. The support arm can provides at least three degrees of freedom of movement and includes at least one sensor for determining a position of the second end. A uniaxial load cell can be operably attached to the second end. The system can also include a processing system operable to receive position data and corresponding force data when the support arm is used to apply a non-normal compression force to the test surface. The data can be used to calculate normal force versus deflection data for the test surface.

Abstract translation: 公开了一种用于测量包括便携式负载偏转装置的材料的正常负载和偏转的系统及其使用方法。 该系统包括具有第一端和与第一端相对的第二端的支撑臂。 第一端可以附着在基面上。 支撑臂可以提供至少三个运动自由度，并且包括用于确定第二端的位置的至少一个传感器。 单轴测力传感器可以可操作地附接到第二端。 该系统还可以包括可操作以在支撑臂用于向测试表面施加非正常压缩力时接收位置数据和对应的力数据的处理系统。 该数据可用于计算试验表面的法向力与挠度数据。

公开(公告)号：US07298092B2

公开(公告)日：2007-11-20

申请号：US11238072

申请日：2005-09-28

Applicant: Muhammad Arif Malik ,  Karl J. Schoenbach

Inventor： Muhammad Arif Malik ,  Karl J. Schoenbach

IPC: H01J7/24

CPC classification number: H05H1/2406 ,  H05H2001/2412 ,  H05H2001/481

Abstract: A novel plasma reactor is provided that includes a discharge chamber with dimensional characteristics and configuration of dielectric and electrodes that optimize efficiency based on the characteristics of the corona discharge streamers generated. Upon application of a pulsed high voltage potential, the discharge chamber enables formation of plasma where surface streamers play a greater role in the overall energy density of the discharge chamber than gas streamers. The formation of gas streamers is constrained. Because surface streamers have a higher energy density, the present invention is able to achieve improved energy efficiency while preserving effectiveness for gas treatment.

Abstract translation: 提供了一种新颖的等离子体反应器，其包括具有尺寸特性和电介质和电极的构造的放电室，其基于产生的电晕放电拖缆的特性优化效率。 在施加脉冲高电压电位时，放电室能够形成等离子体，其中表面飘带在排气室的整体能量密度方面比气体拖缆发挥更大的作用。 瓦斯拖缆的形成受到限制。 由于表面拖缆具有较高的能量密度，本发明能够实现提高的能量效率，同时保持气体处理的有效性。

公开(公告)号：US6063043A

公开(公告)日：2000-05-16

申请号：US186596

申请日：1998-11-05

Applicant: Martin Meyer ,  Robert A. Mevorach

Inventor： Martin Meyer ,  Robert A. Mevorach

IPC: A61B7/00 ,  A61B5/00

CPC classification number: A61B7/00 ,  A61B5/7435

Abstract: A passive acoustic method of detecting the presence or absence of vesicoureteral reflux in a patient comprises the steps of amplifying sound from the abdomen of the patient from a time just prior to the onset of urination in the patient, and then detecting the presence or absence of an audio signal characteristic of vesicureteral reflux in the amplified sound, the presence of the signal indicating the presence of vesicoureteral reflux in the patient. Apparatus and computer program code products for carrying out the invention are also provided.

Abstract translation: 用于检测患者膀胱输尿管反流存在或不存在的被动声学方法包括以下步骤：从患者的排尿发生之前的时间起放大患者腹部的声音，然后检测是否存在 放大声音中的输尿管反流特征的音频信号，存在表示患者膀胱输尿管反流存在的信号。 还提供了用于实施本发明的装置和计算机程序代码产品。

公开(公告)号：US20250025692A1

公开(公告)日：2025-01-23

申请号：US18713624

申请日：2022-09-23

Applicant: OLD DOMINION UNIVERSITY RESEARCH FOUNDATION

Inventor： Andrei G. PAKHOMOV ,  Vitalii KIM ,  Iurii SEMENOV ,  Emily GUDVANGEN

IPC: A61N1/36 ,  A61N1/04

Abstract: Methods and apparatuses for applying energy to a target tissue or cell are described herein. These methods and apparatuses may use one or more pairs of stimulating electrodes and a dedicated ground electrode to locally apply energy to a target tissue or cell at or adjacent the dedicated ground electrode.

公开(公告)号：US11351368B2

公开(公告)日：2022-06-07

申请号：US16669419

申请日：2019-10-30

Applicant: Old Dominion University Research Foundation

Inventor： Andrei G. Pakhomov ,  Shu Xiao ,  Olga N. Pakhomova ,  Maura Casciola

IPC: A61N1/36 ,  A61N1/08 ,  A61N1/04

Abstract: Methods and apparatuses (systems, devices, etc.) for treating biological tissue to evoke one or more desirable biological and/or physiological effects using pulsed electric fields in the sub-microsecond range at very low electric field strength (e.g., less than 1 kV/cm) but at high (e.g., megahertz) frequencies.

公开(公告)号：US11020590B2

公开(公告)日：2021-06-01

申请号：US16104089

申请日：2018-08-16

Applicant: Old Dominion University Research Foundation

Inventor： Andrei G. Pakhomov ,  Olga N. Pakhomova ,  Shu Xiao

IPC: A61N1/32 ,  A61N1/36 ,  A61N1/04 ,  C12N13/00

Abstract: Provided herein are methods of generating a biologically effective unipolar nanosecond electric pulse by superposing two biologically ineffective bipolar nanosecond electric pulses and related aspects, such as electroporation and/or therapeutic applications of these methods to non-invasively target electrostimulation (ES) selectively to deep tissues and organs.

公开(公告)号：US10905874B2

公开(公告)日：2021-02-02

申请号：US15922758

申请日：2018-03-15

Applicant: Eastern Virginia Medical School ,  Old Dominion University Research Foundation

Inventor： Richard Nuccitelli ,  Stephen J. Beebe ,  Karl H. Schoenbach

IPC: A61N1/20 ,  A61N1/32

Abstract: Methods for a new, drug-free therapy for treating solid skin tumors through the application of nanosecond pulsed electric fields (“nsPEFs”) are provided. In one embodiment of the invention, the cells are melanoma cells, and the applied nsPEFs penetrate into the interior of tumor cells and cause tumor cell nuclei to rapidly shrink and tumor blood flow to stop. This new technique provides a highly localized targeting of tumor cells with only minor effects on overlying skin.

公开(公告)号：US20210026943A1

公开(公告)日：2021-01-28

申请号：US16550450

申请日：2019-08-26

Applicant: Old Dominion University Research Foundation

Inventor： Lauren Nicole Tiller ,  Catherine Angelini ,  Sarah Leibner ,  Jeremiah D. Still

IPC: G06F21/36 ,  H04L9/32 ,  G06F21/62

Abstract: The present invention relates to a system and method for authentication of user credentials utilizing a combination of both alphanumeric and graphical password generation and retrieval techniques which includes generating a map with a plurality of symbols populated on the map, wherein the symbols include a plurality of targets and distractors which are associated with alphanumeric characters and wherein a user can utilize the symbols on the map in a particular custom path on the map so as to aid in the generation and future recollection of a selected complex alphanumeric password.