公开(公告)号：US20200240903A1

公开(公告)日：2020-07-30

申请号：US16845560

申请日：2020-04-10

Applicant: Meso Scale Technologies, LLC.

Inventor： Jacob N. Wohlstadter ,  Eli Glezer ,  James Wilbur ,  George Sigal ,  Kent Johnson ,  Charles Clinton ,  Alan Kishbaugh ,  Bandele Jeffrey-Coker ,  Jeff D. Debad ,  Alan B. Fischer

IPC: G01N21/25 ,  B01L3/00 ,  G01N21/66 ,  G01N21/76 ,  B01L9/00

Abstract: Luminescence test measurements are conducted using an assay module having integrated electrodes with a reader apparatus adapted to receive assay modules, induce luminescence, preferably electrode induced luminescence, in the wells or assay regions of the assay modules and measure the induced luminescence.

公开(公告)号：US10725059B2

公开(公告)日：2020-07-28

申请号：US15564581

申请日：2016-04-06

Applicant: Meso Scale Technologies, LLC

Inventor： Eli N. Glezer ,  Carl Edens ,  Bandele Jeffrey-Coker ,  Sandor Kovacs ,  Christopher Frye

IPC: G01N35/00 ,  B01F11/00 ,  G01N35/10 ,  G01N33/543 ,  B06B1/16

Abstract: The present invention relates to a system for performing assays on a solid phase to measure the level of analyte in a sample. Such a system may perform immunoassays using electrochemiluminescence (ECL) including a counterbalanced orbital shaking apparatus for assay consumables.

公开(公告)号：USD880096S1

公开(公告)日：2020-03-31

申请号：US29591981

申请日：2017-01-25

Applicant: Meso Scale Technologies, LLC.

Designer： Jacob N. Wohlstadter ,  Rodger Darin Osborne ,  Jennifer Parker ,  Aaron Leimkuehler ,  Manish Kochar ,  Peter Bosco ,  Michael Wade

公开(公告)号：US20200001288A1

公开(公告)日：2020-01-02

申请号：US16455392

申请日：2019-06-27

Applicant: MESO SCALE TECHNOLOGIES, LLC

Inventor： Charles M. CLINTON ,  Jacob N. Wohlstadter

IPC: B01L3/00

Abstract: We describe a detection module useful with an apparatus and/or system for conducting luminescence assays, and a kit, a system, an apparatus, and a method incorporating the detection module.

公开(公告)号：US20190391140A1

公开(公告)日：2019-12-26

申请号：US16564208

申请日：2019-09-09

Applicant: MESO SCALE TECHNOLOGIES, LLC.

Inventor： Anahit Aghvanyan ,  Eli N. Glezer ,  John Kenten ,  George Sigal ,  Martin Stengelin ,  David Routenberg

IPC: G01N33/543 ,  C12Q1/6844 ,  C12Q1/6837 ,  C12Q1/6832

Abstract: The present invention is directed to methods for improving assay specificity and performance in binding assays.

公开(公告)号：US10436784B2

公开(公告)日：2019-10-08

申请号：US14854514

申请日：2015-09-15

Applicant: Meso Scale Technologies, LLC ,  The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc.

Inventor： William F Blakely ,  Eli N. Glezer ,  John Kenten ,  Sudeep Kumar ,  Anu Mathew ,  Natalia I. Ossetrova ,  George Sigal

IPC: G01N33/53 ,  G01N33/569 ,  G01N33/68 ,  G01N33/566

Abstract: The present invention relates to methods and kits to assess an absorbed dose of ionizing radiation and/or the severity of tissue injury from radiation in a patient. The invention also relates to algorithms used to calculate an absorbed dose of radiation based on biomarker measurements of a plurality of biomarkers that are altered relative to a normal control in the event of radiation exposure.

公开(公告)号：US10413904B2

公开(公告)日：2019-09-17

申请号：US14847381

申请日：2015-09-08

Applicant: MESO SCALE TECHNOLOGIES, LLC

Inventor： Yihong Claire Lu ,  Pankaj Oberoi

IPC: B01L3/00 ,  C12Q1/6876 ,  G01N33/543 ,  C12Q1/6804 ,  G01N33/68 ,  C12Q1/6816

Abstract: The invention relates to kits and components thereof used in the conduct of solid-phase binding assays.

公开(公告)号：US20190178787A1

公开(公告)日：2019-06-13

申请号：US16219030

申请日：2018-12-13

Applicant: Meso Scale Technologies, LLC

Inventor： Nicholas Anderson ,  Jeffery Debad ,  Eli N. Glezer ,  Sudeep Kumar ,  Noel Lawrence ,  Kenneth Page ,  George Sigal ,  Sharon West

IPC: G01N21/05 ,  G01N21/03 ,  G01N21/69 ,  G01N21/76 ,  G01F23/02 ,  G01F23/292 ,  B01L3/00

Abstract: Assay cartridges are described that have a detection chamber, preferably having integrated electrodes, and other fluidic components which may include sample chambers, waste chambers, conduits, vents, bubble traps, reagent chambers, dry reagent pill zones and the like. In certain embodiments, these cartridges are adapted to receive and analyze a sample collected on an applicator stick. Also described are kits including such cartridges and a cartridge reader configured to analyze an assay conducted using an assay cartridge.

公开(公告)号：USD850290S1

公开(公告)日：2019-06-04

申请号：US29571996

申请日：2016-07-22

Applicant: Meso Scale Technologies, LLC.

Designer： Eric Jones ,  Jennifer Parker ,  Manish Kochar ,  Peter Bosco

公开(公告)号：US10281678B2

公开(公告)日：2019-05-07

申请号：US14147216

申请日：2014-01-03

Applicant: Meso Scale Technologies, LLC

Inventor： Ian Chamberlin ,  Charles M. Clinton ,  Eli N. Glezer ,  Bandele Jeffrey-Coker ,  Manish Kochar ,  Sandor Kovacs ,  D. T. Le ,  Aaron Leimkuehler ,  George Sigal ,  Leo Tabakin ,  Jon Willoughby

IPC: G02B7/36 ,  G01N35/02 ,  G01N21/25 ,  G01N21/64

Abstract: Apparatuses, systems, method, reagents, and kits for conducting assays as well as process for their preparation are described. They are particularly well suited for conducting automated analysis in a multi-well plate assay format.