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109 条记录 (耗时 0.017 秒)

    Nonsymbiotic plant hemoglobins to maintain cell energy status
    101.
    发明授权
    Nonsymbiotic plant hemoglobins to maintain cell energy status 失效
    非共生植物血红蛋白维持细胞能量状态

    公开(公告)号：US06936749B1

    公开(公告)日：2005-08-30

    申请号：US09720206

    申请日：1999-06-24

    申请人： Phillip Guy ,  Stephen Duff ,  Nie Xianzhou ,  Robert Hill ,  Douglas Durnin ,  Aleksander Sowa

    发明人： Phillip Guy ,  Stephen Duff ,  Nie Xianzhou ,  Robert Hill ,  Douglas Durnin ,  Aleksander Sowa

    IPC分类号： A01H5/00 ,  A61K35/12 ,  C07K14/415 ,  C07K14/805 ,  C12N1/20 ,  C12N15/29 ,  C12N15/82

    CPC分类号： C07K14/415 ,  A61K35/12 ,  C07K14/805 ,  C12N1/20 ,  C12N15/8261 ,  Y02A40/146

    摘要： Nonsymbiotic hemoglobins are broadly present across evolution; however, the function of these proteins is unknown. Cultured maize cells have been transformed to constitutively express a barley hemoglobin gene in either the sense (HB+) or antisense (HB−) orientation. Hemoglobin protein in the transformed cell lines was correspondingly higher or lower than in wild type cells under normal atmospheric conditions. Limiting oxygen availability, by placing the cells in a nitrogen atmosphere for 12 hours, had little effect on the energy status of cells constitutively expressing hemoglobin, but had a pronounced effect on both wild type and HB− cells, where ATP levels declined by 27% and 61% respectively. Energy charge was relatively unaffected by the treatment in HB+ and wild type cells, but was reduced from 0.91 to 0.73 in HB− cells suggesting that the latter were incapable of maintaining their energy status under the low oxygen regime. Similar results were observed with P. aeruginosa cells transformed with an Hb expression vector. It is suggested that nonsymbiotic hemoglobins act to maintain the energy status of cells in low oxygen environments and that they accomplish this effect by promoting glycolytic flux through NADH oxidation, resulting in increased substrate level phosphorylation. Nonsymbiotic hemoglobins are likely ancestors of an early form of hemoglobin that sequestered oxygen in low oxygen environments, providing a source of oxygen to oxidize NADH to provide ATP for cell growth and development. This in turn suggests that cells containing increased levels of Hb protein will survive longer under low oxygen tension or high energy demand.

    摘要翻译： 非共生血红蛋白在进化中广泛存在; 然而，这些蛋白质的功能是未知的。 培养的玉米细胞已被转化以组合式表达大鼠血红蛋白基因（HB + />）或反义（HB ）方向。 在正常大气条件下，转化细胞系中的血红蛋白蛋白质相对较高或低于野生型细胞。 通过将细胞置于氮气气氛中12小时来限制氧气供应对组成型表达血红蛋白的细胞的能量状态几乎没有影响，但对野生型和HB 细胞都具有显着的作用， ATP水平分别下降了27％和61％。 能量电荷相对不受HB +和/或野生型细胞治疗的影响，但在HB 细胞中从0.91降低至0.73，表明后者不能维持 低氧状态下的能量状态。 用Hb表达载体转化的铜绿假单胞菌细胞观察到类似的结果。 建议非共生血红蛋白起作用以维持低氧环境中细胞的能量状态，并通过促进糖酵解通过NADH氧化来实现这一作用，从而增加底物水平的磷酸化。 非共生血红蛋白可能是早期形式的血红蛋白的祖先，其在低氧环境中螯合氧，提供氧气来氧化NADH以提供ATP用于细胞生长和发育。 这反过来表明，含有较高水平的Hb蛋白的细胞将在低氧压力或高能量需求下生存更长时间。

    Handheld wireless communication devices with antenna having parasitic element
    102.
    发明授权
    Handheld wireless communication devices with antenna having parasitic element 失效
    带天线的手持无线通信设备具有寄生元件

    公开(公告)号：US06603430B1

    公开(公告)日：2003-08-05

    申请号：US09802805

    申请日：2001-03-09

    申请人： Robert Hill ,  Juan Zavala

    发明人： Robert Hill ,  Juan Zavala

    IPC分类号： H01Q138

    CPC分类号： H01Q1/38 ,  H01Q1/242 ,  H01Q1/36 ,  H01Q9/065 ,  H01Q9/26 ,  H01Q9/42

    摘要： A simple internal or partly internal antenna system for optimizing the radiation pattern from hand held wireless communications devices HHWCD such as hand-held data devices and cellular telephones is disclosed. The antenna system consists of an essentially internal or partly internal asymmetrical dipole with quarter-wave resonator section and radiating planar section, in conjunction with a planar parasitic director element. The radiating planar section may be the ground traces of the HHWCDs printed wiring board PWB. The antenna system provides for single or multiple frequency band operation.

    摘要翻译： 公开了用于优化手持式无线通信设备H​​HWCD（例如手持式数据设备和蜂窝电话）的辐射模式的简单内部或部分内部天线系统。 天线系统由具有四分之一波长谐振器部分和辐射平面部分的基本内部或部分内部不对称偶极子组成，与平面寄生导体元件结合。 辐射平面部分可以是HHWCD印刷线路板PWB的接地迹线。 天线系统提供单频或多频段操作。

    Compact dual frequency antenna with multiple polarization
    103.
    发明授权
    Compact dual frequency antenna with multiple polarization 失效
    紧凑型双频天线，具有多极化

    公开(公告)号：US06407710B2

    公开(公告)日：2002-06-18

    申请号：US09835659

    申请日：2001-04-16

    申请人： Donald Keilen ,  Patrick McKivergan ,  Matthew Commens ,  Robert Hill

    发明人： Donald Keilen ,  Patrick McKivergan ,  Matthew Commens ,  Robert Hill

    IPC分类号： H01Q124

    CPC分类号： H01Q9/0421 ,  H01Q1/242 ,  H01Q1/243 ,  H01Q1/38 ,  H01Q5/371 ,  H01Q9/0442 ,  H01Q9/045 ,  H01Q9/26 ,  H01Q9/285

    摘要： An asymmetrical dipole antenna is disclosed consisting of a planar conductor, matching network, and resonator. The antenna is compact, may operate on one or more frequency bands, and is suitable for high volume production. The antenna exhibits simultaneous dual linear polarizations and a unidirectional pattern in at least one of its operating frequency ranges when configured for multiple-band operation. Applications for the antenna include wireless communication devices such as cellular telephones or data devices.

    摘要翻译： 公开了一种由平面导体，匹配网络和谐振器组成的非对称偶极子天线。 天线紧凑，可以在一个或多个频带上工作，适合大批量生产。 当配置为多频带操作时，天线在其工作频率范围的至少一个中呈现同时的双线性偏振和单向模式。 用于天线的应用包括诸如蜂窝电话或数据设备的无线通信设备。

    Dual polarization slot antenna assembly
    104.
    发明授权
    Dual polarization slot antenna assembly 失效
    双偏振缝天线组件

    公开(公告)号：US06404394B1

    公开(公告)日：2002-06-11

    申请号：US09746569

    申请日：2000-12-21

    申请人： Robert Hill

    发明人： Robert Hill

    IPC分类号： H01Q124

    CPC分类号： H01Q13/106 ,  H01Q1/243 ,  H01Q1/38 ,  H01Q9/0421 ,  H01Q13/10

    摘要： The invention discloses a slot antenna assembly for a wireless communications device having a printed wiring board element defining at least a ground plane and an input/output RF connection point. The antenna assembly further includes a dielectric element having a pair of opposed major surfaces; a conductive feed circuit disposed upon one of the major surfaces, said feed circuit coupled to the RF connection point of the printed wiring board; and a resonator circuit including a pair of resonator arms oriented approximately parallel to each other, said pair of resonator arms being coupled together via a conductive connection and defining a substantially elongate slot, one of said pair of resonator arms being conductively coupled to the feed circuit, and the other of said pair of resonator arms being conductively coupled to the ground plane of the printed wiring board. The slot antenna according to the present invention may be disposed within an associated wireless communications device relative to a ground plane element of a printed wiring board, or may be disposed separately away from the associated wireless communications device.

    摘要翻译： 本发明公开了一种用于无线通信设备的缝隙天线组件，其具有限定至少接地平面和输入/输出RF连接点的印刷线路板元件。 天线组件还包括具有一对相对的主表面的电介质元件; 设置在所述主表面之一上的导电馈电电路，所述馈电电路耦合到印刷线路板的RF连接点; 以及谐振器电路，其包括彼此大致平行取向的一对谐振器臂，所述一对谐振器臂经由导电连接耦合在一起并且限定基本上细长的槽，所述一对谐振臂中的一个导体地耦合到馈电电路 并且所述一对谐振器臂中的另一个导电地耦合到印刷线路板的接地平面。 根据本发明的缝隙天线可以相对于印刷线路板的接地平面元件设置在相关联的无线通信设备内，或者可以相对于相关联的无线通信设备分开设置。

    Marking instruments
    105.
    发明授权
    Marking instruments 失效
    标记仪器

    公开(公告)号：US06328496B1

    公开(公告)日：2001-12-11

    申请号：US09819037

    申请日：2001-03-08

    申请人： Alan Robert Hill ,  Clive Barnes ,  Charles Christopher Packham ,  Mark Arthur Seddon

    发明人： Alan Robert Hill ,  Clive Barnes ,  Charles Christopher Packham ,  Mark Arthur Seddon

    IPC分类号： B43K700

    CPC分类号： B43K7/005 ,  B43K23/004

    摘要： A marking instrument, such as a pen, is disclosed. The marking instrument includes a marking tip carried at the end of a tubular member for conducting marking fluid to the marking tip. The marking tip includes a tubular rear end section of circular cross-section. The tubular member is elliptical in cross-section and is attached to the tubular rear end section of the marking tip at an angle to the longitudinal axis of the tubular member. The elliptical shape of the tubular member allows for a circular profile opening when the tubular member is cut at an angle to join the tubular rear end section of the marking tip. Because the complementary profiles are circular in shape at the connection plane, it is not necessary to rotationally orient the components when bringing them together to be joined. The tubular rear end section of the marking tip may also be elliptical in shape, thereby requiring both the tubular rear end section and the tubular member to be cut at similar angles to produce the circular profile opening.

    摘要翻译： 公开了诸如笔的标记工具。 标记仪器包括承载在管状构件的端部处的标记末端，用于将标记流体引导到标记末端。 标记末端包括圆形横截面的管状后端部分。 管状构件的横截面为椭圆形，并且以与管状构件的纵向轴线成一定角度附接到标记尖端的管状后端部分。 当管状构件以一定角度切割以连接标记末端的管状后端部分时，管状构件的椭圆形状允许圆形轮廓打开。 由于互补型材在连接面处是圆形的，所以当将它们组合在一起以进行接合时，不必旋转地定向部件。 标记尖端的管状后端部分也可以是椭圆形的，从而要求管状后端部分和管状部件都以相似的角度切割以产生圆形轮廓开口。

    Asymmetric dipole antenna assembly
    106.
    发明授权
    Asymmetric dipole antenna assembly 有权
    非对称偶极天线组件

    公开(公告)号：US06239765B1

    公开(公告)日：2001-05-29

    申请号：US09382179

    申请日：1999-08-24

    申请人： Greg F. Johnson ,  Robert Hill ,  Don Keilen

    发明人： Greg F. Johnson ,  Robert Hill ,  Don Keilen

    IPC分类号： H01Q138

    CPC分类号： H01Q1/38 ,  H01Q1/243 ,  H01Q5/371 ,  H01Q5/40 ,  H01Q9/0421 ,  H01Q9/285 ,  H01Q13/08

    摘要： An asymmetric dipole antenna assembly is provided for wireless communications devices, and includes separate upper and lower conductor traces and a low impedance feedpoint at the junction of the conductor traces. The upper conductor trace may include a matching network and may be printed on a planar printed circuit board mounted proximate the top of the a hand-held wireless transceiver. The upper conducting trace provides ¼ wave resonance over a desired frequency range and a 50 ohm input impedance for the antenna. The lower conductor trace may be provided by the ground trace of the wireless device circuitry, requiring only a minimum effective trace length of ¼ wavelength at the lowest frequency of operation. Polarization of the antenna is determined by the orientation of the longest dimension of the lower conductor.

    摘要翻译： 为无线通信设备提供非对称偶极天线组件，并且在导体迹线的接合处包括单独的上下导体迹线和低阻抗馈电点。 上导体迹线可以包括匹配的网络并且可以印刷在靠近手持式无线收发器的顶部安装的平面印刷电路板上。 上导电迹线在期望的频率范围内提供1/4波谐振，并为天线提供50欧姆的输入阻抗。 下导体迹线可以由无线设备电路的接地迹线提供，只需要最低频率处的最小有效波长长度为1/4波长。 天线的极化由下导体的最长尺寸的取向决定。