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公开(公告)号:US20230046495A1
公开(公告)日:2023-02-16
申请号:US17980384
申请日:2022-11-03
Applicant: Edwards Lifesciences Corporation
Inventor: Travis Zenyo Oba , Matthew A. Peterson , Glen T. Rabito , Alexander H. Cooper , David Robert Landon , J. Brent Ratz , Seung-Beom Yi
Abstract: A replacement mitral valve prosthesis includes a support structure and a valve body having three flexible leaflets. The support structure preferably includes an internal valve frame and an external sealing frame. The valve frame supports the flexible leaflets. The sealing frame is adapted to conform to the shape of the native mitral valve annulus. The sealing frame may be coupled to an inlet end of the valve frame, an outlet end of the valve frame, or both. A plurality of anchors is coupled to the outlet end of the valve frame. The anchors extend radially outwardly for placement behind native leaflets. The prosthesis preferably includes a skirt disposed along an exterior of the external sealing frame. The prosthesis is collapsible for delivery into the heart via a delivery catheter. The prosthesis is configured to self-expand for deployment in the heart when released from the delivery catheter.
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公开(公告)号:US11224507B2
公开(公告)日:2022-01-18
申请号:US16506886
申请日:2019-07-09
Applicant: Edwards Lifesciences Corporation
Inventor: Matthew A. Peterson , Seung-Beom Yi , Siddharth Vad , Travis Zenyo Oba , Lauren R. Freschauf , Amanda French , Yaron Keidar , Yuanlong Du , Gregory Bak-Boychuk , Kevin M. Golemo , Alexander H. Cooper
IPC: A61F2/24
Abstract: A heart valve prosthesis for replacing a native mitral valve includes a self-expanding frame with a plurality of anchoring members disposed along the lower region. A valve body is positioned within the self-expanding frame and includes a plurality of leaflets configured to allow blood flow through the self-expanding frame in only one direction. A skirt surrounds the self-expanding frame and is spaced apart therefrom for contacting surrounding tissue and impeding blood flow around the self-expanding frame. The skirt may be reinforced with wires to help maintain a desired shape. The leaflets in the valve body are preferably connected to the self-expanding frame through one or more intermediate components such that the valve body is spaced radially inwardly from an inner surface of the self-expanding frame.
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公开(公告)号:US10758342B2
公开(公告)日:2020-09-01
申请号:US16171263
申请日:2018-10-25
Applicant: Edwards Lifesciences Corporation
Inventor: Mark Chau , Marlowe E. Patterson , Seung-Beom Yi , Stephen C. Geist , Travis Zenyo Oba
IPC: A61F2/24
Abstract: A prosthetic mitral valve can include an outer frame, an inner frame, a valve structure, and a sealing member. The outer frame comprises a plurality of first struts arranged in a lattice pattern and defining a first lumen. The outer frame is self-expandable from a compressed state to an expanded state. The inner frame comprises a plurality of second struts arranged in a lattice pattern and defining a second lumen. The inner frame is disposed within the first lumen of the outer frame, is self-expandable from a compressed state to an expanded state. The valve structure comprises three leaflets made from pericardium and is mounted within the second lumen of the inner frame. The sealing member is coupled to and extends radially outwardly from an atrial end of the outer frame and is configured to engage native tissue of the heart on an atrial side of the native mitral valve.
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公开(公告)号:USRE47490E1
公开(公告)日:2019-07-09
申请号:US15367099
申请日:2016-12-01
Applicant: Edwards Lifesciences Corporation
Inventor: John F Migliazza , Hugues LaFrance , Harvey H Chen , Travis Zenyo Oba , Manouchehr A Miraki
Abstract: A prosthetic valve assembly and method of implanting same is disclosed. The prosthetic valve assembly includes a prosthetic valve formed by support frame and valve leaflets, with one or more tethers each having a first end secured to the support frame and the second end attached to, or configured for attachment to, to papillary muscles or other ventricular tissue. The tether is configured and positioned so as to avoid contact or other interference with movement of the valve leaflets, while at the same time providing a tethering action between the support frame and the ventricular tissue. The valve leaflets may be flexible (e.g., so-called tissue or synthetic leaflets) or mechanical.
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公开(公告)号:US20190151084A1
公开(公告)日:2019-05-23
申请号:US16248706
申请日:2019-01-15
Applicant: Edwards Lifesciences Corporation
Inventor: Rafael Pintor , Mark Chau , Travis Zenyo Oba , August R. Yambao , Louis A. Campbell , Tammy Huntley , Quinggang Zeng , Carey L. Cristea , Faisal Kalam
IPC: A61F2/24
CPC classification number: A61F2/2418 , A61F2/2409 , A61F2/243 , A61F2/2433 , A61F2220/0016 , A61F2220/0025 , A61F2220/005 , A61F2220/0075 , A61F2220/0083 , A61F2230/0054 , A61F2230/0067 , A61F2230/0069 , A61F2230/0078 , A61F2250/006
Abstract: A heart valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The prosthetic valve has a base stent that is deployed at a treatment site, and a valve component configured to quickly connect to the base stent. The base stent may take the form of a self- or balloon-expandable stent that expands outward against the native valve with or without leaflet excision. The valve component has a non-expandable prosthetic valve and a self- or balloon-expandable coupling stent for attachment to the base stent, thereby fixing the position of the valve component relative to the base stent. The prosthetic valve may be a commercially available to valve with a sewing ring and the coupling stent attaches to the sewing ring. The system is particularly suited for rapid deployment of heart valves in a conventional open-heart surgical environment. A catheter-based system and method for deployment is provided.
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公开(公告)号:US10111748B2
公开(公告)日:2018-10-30
申请号:US15455713
申请日:2017-03-10
Applicant: Edwards Lifesciences Corporation
Inventor: Mark Chau , Marlowe E. Patterson , Seung-Beom Yi , Stephen C. Geist , Travis Zenyo Oba
IPC: A61F2/24
Abstract: A prosthetic apparatus for implantation in a native mitral valve includes a main body for placement within the native mitral annulus. The main body is compressible to a radially compressed state for delivery into the heart and is self-expandable from the compressed state to a radially expanded state for implantation. A valve structure is mounted within a lumen of the main body and preferably forms three leaflets made of pericardium. An atrial sealing member is disposed along an atrial portion of the main body and ventricular anchors are coupled to a ventricular portion of the main body. The atrial sealing member impedes the flow of blood between the main body and the native annulus. The ventricular anchors are positioned outside the main body for capturing native mitral valve leaflets between the main body and the ventricular anchors.
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公开(公告)号:US20170296336A1
公开(公告)日:2017-10-19
申请号:US15423378
申请日:2017-02-02
Applicant: Edwards Lifesciences Corporation
Inventor: Rafael Pintor , Mark Chau , Travis Zenyo Oba , August R. Yambao , Louis A. Campbell , Tammy Huntley , Qinggang Zeng , Carey L. Cristea , Faisal Kalam
IPC: A61F2/24
CPC classification number: A61F2/2418 , A61F2/2409 , A61F2/243 , A61F2/2433 , A61F2220/0016 , A61F2220/0025 , A61F2220/005 , A61F2220/0075 , A61F2220/0083 , A61F2230/0054 , A61F2230/0067 , A61F2230/0069 , A61F2230/0078 , A61F2250/006
Abstract: A heart valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The prosthetic valve has a base stent that is deployed at a treatment site, and a valve component configured to quickly connect to the base stent. The base stent may take the form of a self-or balloon-expandable stent that expands outward against the native valve with or without leaflet excision. The valve component has a non-expandable prosthetic valve and a self-or balloon-expandable coupling stent for attachment to the base stent, thereby fixing the position of the valve component relative to the base stent. The prosthetic valve may be a commercially available to valve with a sewing ring and the coupling stent attaches to the sewing ring. The system is particularly suited for rapid deployment of heart valves in a conventional open-heart surgical environment. A catheter-based system and method for deployment is provided.
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公开(公告)号:US20160338826A1
公开(公告)日:2016-11-24
申请号:US15227238
申请日:2016-08-03
Applicant: Edwards Lifesciences Corporation
Inventor: Mark Chau , Marlowe E. Patterson , Seung-Beom Yi , Stephen C. Geist , Travis Zenyo Oba
IPC: A61F2/24
CPC classification number: A61F2/2412 , A61F2/2409 , A61F2/2418 , A61F2/2427 , A61F2/2445 , A61F2/246 , A61F2210/0014 , A61F2220/0008 , A61F2220/0016 , A61F2230/0069 , A61F2250/006 , A61F2250/0063
Abstract: A prosthetic apparatus for implantation in a native mitral valve includes a main body for placement within the native mitral annulus. The main body is compressible to a radially compressed state for delivery into the heart and is self-expandable from the compressed state to a radially expanded state for implantation. A valve structure is mounted within a lumen of the main body and preferably forms three leaflets made of pericardium. An atrial sealing member is disposed along an atrial portion of the main body and ventricular anchors are coupled to a ventricular portion of the main body. The atrial sealing member impedes the flow of blood between the main body and the native annulus. The ventricular anchors are positioned outside the main body for capturing native mitral valve leaflets between the main body and the ventricular anchors.
Abstract translation: 用于植入天然二尖瓣的假体装置包括用于放置在天然二尖瓣环内的主体。 主体可压缩到径向压缩状态,用于输送到心脏中,并且可以从压缩状态自扩张到用于植入的径向扩张状态。 阀结构安装在主体的内腔中,优选形成由心包制成的三个传单。 心房密封构件沿着主体的心房部分设置,并且心室锚固件联接到主体的心室部分。 心房密封件妨碍主体和天然环之间的血液流动。 心室锚定位于主体外部,用于捕获主体和心室锚之间的原生二尖瓣小叶。
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公开(公告)号:US20160317290A1
公开(公告)日:2016-11-03
申请号:US15204874
申请日:2016-07-07
Applicant: Edwards Lifesciences Corporation
Inventor: Mark Chau , Travis Zenyo Oba , Sergio Delgado , Robert C. Taft
IPC: A61F2/24
CPC classification number: A61F2/2436 , A61F2/2412 , A61F2/243 , A61F2/2433 , A61F2/2442 , A61F2/2445 , A61F2/2454 , A61F2/2457 , A61F2/246 , A61F2/2463 , A61F2/2466 , A61F2230/0069 , A61F2250/0003
Abstract: This disclosure pertains generally to prosthetic devices and related methods for helping to seal native heart valves and prevent or reduce regurgitation therethrough, as well as devices and related methods for implanting such prosthetic devices. In some cases, a spacer having a single anchor can be implanted within a native heart valve. In some cases, a spacer having dual anchors can be implanted within a native heart valve. In some cases, devices can be used to extend the effective length of a native heart valve leaflet.
Abstract translation: 本公开总体上涉及用于帮助密封天然心脏瓣膜并防止或减少反流的假体装置和相关方法,以及用于植入这种假体装置的装置和相关方法。 在一些情况下,具有单个锚的间隔物可以植入天然心脏瓣膜内。 在一些情况下,具有双重锚的间隔物可以植入天然心脏瓣膜内。 在某些情况下,可以使用装置来延长天然心脏瓣膜小叶的有效长度。
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公开(公告)号:US09005278B2
公开(公告)日:2015-04-14
申请号:US13660780
申请日:2012-10-25
Applicant: Edwards Lifesciences Corporation
Inventor: Rafael Pintor , Mark Chau , Travis Zenyo Oba , August R. Yambao , Louis A. Campbell , Tammy Huntley , Quinggang Zeng , Carey L. Cristea , Faisal Kalam
IPC: A61F2/24
CPC classification number: A61F2/2418 , A61F2/2409 , A61F2/243 , A61F2/2433 , A61F2220/0016 , A61F2220/0025 , A61F2220/005 , A61F2220/0075 , A61F2220/0083 , A61F2230/0054 , A61F2230/0067 , A61F2230/0069 , A61F2230/0078 , A61F2250/006
Abstract: A heart valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The prosthetic valve has a base stent that is deployed at a treatment site, and a valve component configured to quickly connect to the base stent. The base stent may take the form of a self- or balloon-expandable stent that expands outward against the native valve with or without leaflet excision. The valve component has a non-expandable prosthetic valve and a self- or balloon-expandable coupling stent for attachment to the base stent, thereby fixing the position of the valve component relative to the base stent. The prosthetic valve may be a commercially available valve with a sewing ring and the coupling stent attaches to the sewing ring. The system is particularly suited for rapid deployment of heart valves in a conventional open-heart surgical environment.
Abstract translation: 提供了可以在手术过程中快速且容易地植入的心脏瓣膜假体。 假体瓣膜具有部署在治疗部位的基部支架和构造成快速连接到基部支架的阀部件。 基底支架可以采取自体或球囊扩张的支架的形式,其在具有或不具有小叶切除的情况下相对于天然瓣膜向外扩张。 阀部件具有不可扩张的假体瓣膜和用于附接到基底支架的自支撑或球囊扩张的联接支架,由此固定阀部件相对于基底支架的位置。 假体阀可以是具有缝合环的市售阀,并且联接支架附接到缝合环。 该系统特别适用于在常规开心手术环境中快速部署心脏瓣膜。
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