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    Methods and systems for neural maintenance and regeneration
    102.
    发明申请
    Methods and systems for neural maintenance and regeneration 审中-公开
    神经维持和再生的方法和系统

    公开(公告)号：US20080015154A1

    公开(公告)日：2008-01-17

    申请号：US11891372

    申请日：2007-08-09

    申请人： Muriel Ishikawa ,  Edward Jung ,  Lowell Wood

    发明人： Muriel Ishikawa ,  Edward Jung ,  Lowell Wood

    IPC分类号： A61K38/18

    CPC分类号： A61K9/0024 ,  A61F11/00 ,  A61K38/185 ,  A61K45/06 ,  A61M5/14276 ,  A61M5/1723 ,  A61M2005/1726 ,  A61M2210/0612 ,  A61M2210/0618 ,  A61M2210/0643 ,  A61K2300/00

    摘要： Methods and systems are described that release one or both of a neurotrophin and an inhibitor of the degradation of the neurotrophin within or in the vicinity of a highly innervated tissue. In some embodiments, the method includes regulating the release of the neurotrophin and the inhibitor of degradation over time. In some embodiments, the method includes monitoring the concentration of the neurotrophin over time. The system may include a device or multiple devices for the release of the neurotrophin and the inhibitor as well as a controller. In some embodiments the system may include a sensor device and/or an imaging device capable of detecting the concentration of the neurotrophin over time. The release of the neurotrophin and inhibitor of degradation may be part of a controlled release system and regulated over time.

    摘要翻译： 描述了释放神经营养因子和神经营养因子在高度维持组织附近或附近的降解的抑制剂中的一种或两种的方法和系统。 在一些实施方案中，该方法包括调节神经营养因子的释放和随时间的降解抑制剂。 在一些实施方案中，该方法包括随时间监测神经营养因子的浓度。 该系统可以包括用于释放神经营养因子和抑制剂的装置或多个装置以及控制器。 在一些实施例中，系统可以包括能够随时间检测神经营养因子浓度的传感器装置和/或成像装置。 神经营养因子和降解抑制剂的释放可以是受控释放系统的一部分并随时间调节。

    Methods and systems for neural maintenance and regeneration
    110.
    发明申请
    Methods and systems for neural maintenance and regeneration 有权
    神经维持和再生的方法和系统

    公开(公告)号：US20060282062A1

    公开(公告)日：2006-12-14

    申请号：US11150861

    申请日：2005-06-10

    申请人： Muriel Ishikawa ,  Edward Jung ,  Lowell Wood

    发明人： Muriel Ishikawa ,  Edward Jung ,  Lowell Wood

    IPC分类号： A61K38/17 ,  A61K9/22

    CPC分类号： A61K9/0024 ,  A61F11/00 ,  A61K38/185 ,  A61K45/06 ,  A61M5/14276 ,  A61M5/1723 ,  A61M2005/1726 ,  A61M2210/0612 ,  A61M2210/0618 ,  A61M2210/0643 ,  A61K2300/00

    摘要： Methods and systems are described that release one or both of a neurotrophin and an inhibitor of the degradation of the neurotrophin within or in the vicinity of a highly innervated tissue. In some embodiments, the method includes regulating the release of the neurotrophin and the inhibitor of degradation over time. In some embodiments, the method includes monitoring the concentration of the neurotrophin over time. The system may include a device or multiple devices for the release of the neurotrophin and the inhibitor as well as a controller. In some embodiments the system may include a sensor device and/or an imaging device capable of detecting the concentration of the neurotrophin over time. The release of the neurotrophin and inhibitor of degradation may be part of a controlled release system and regulated over time.

    摘要翻译： 描述了释放神经营养因子和神经营养因子在高度维持组织附近或附近的降解的抑制剂中的一种或两种的方法和系统。 在一些实施方案中，该方法包括调节神经营养因子的释放和随时间的降解抑制剂。 在一些实施方案中，该方法包括随时间监测神经营养因子的浓度。 该系统可以包括用于释放神经营养因子和抑制剂的装置或多个装置以及控制器。 在一些实施例中，系统可以包括能够随时间检测神经营养因子浓度的传感器装置和/或成像装置。 神经营养因子和降解抑制剂的释放可以是受控释放系统的一部分并随时间调节。