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公开(公告)号：US20190017000A1
公开(公告)日：2019-01-17
申请号：US16135568
申请日：2018-09-19
摘要： A method for formulating a cleaning composition contains the step of coating a granular absorbent material with a coating agent to produce a coated absorbent material and mixing the coated absorbent material with a sanitation agent, wherein the coated absorbent material absorbs the sanitation agent to form the cleaning composition. The resulting cleaning composition may be used for cleaning up pathogens or hazardous materials. The cleaning composition may also functions as a liquefiable dry cleaning powder for public areas in response to bodily fluid incidents. A coating method of a non-toxic bio static film on a high surface area solid is disclosed.
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公开(公告)号：US20190004065A1
公开(公告)日：2019-01-03
申请号：US15901523
申请日：2018-02-21
发明人： Byron D. FORD , Gregory FORD
IPC分类号： G01N33/68 , C12Q1/6883
摘要： Biomarkers for stroke and methods for their detection are disclosed. In one aspect, the present application discloses biomarkers for the diagnosis of stroke in a subject. In another aspect, the application discloses a method for the diagnosis of stroke in a subject. The method comprises detection of stroke biomarkers in cerebrospinal fluid, blood, serum or PMBCs of a subject. Also disclosed is a kit for the detection of biomarkers for the diagnosis of stroke in a subject.
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公开(公告)号：US20180310866A1
公开(公告)日：2018-11-01
申请号：US16030213
申请日：2018-07-09
发明人： Glenda Wrenn
CPC分类号： A61B5/16 , A61B5/0022 , A61B5/4088 , A61B5/6888 , A61B5/746 , G16H10/20 , G16H10/60 , G16H20/70 , G16H50/30
摘要： A method and system for assessing the mental state or behavioral disorder of a subject is disclosed. The system includes a display, an input device, a processor, a database and matrix for converting the responses to one or more assessment scores. The disclosure also relates to a method for treating a behavioral disorder using the method and a system described herein.
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公开(公告)号：US20180305412A1
公开(公告)日：2018-10-25
申请号：US16030430
申请日：2018-07-09
IPC分类号： C07K14/005 , C12N7/00 , A61K45/06 , A61K47/64 , A61K38/16
摘要： A multipartite peptide that inhibits release of exosomes in a cell, comprising an N-terminal end and a C-terminal end and comprising at least one secretion modifying region (SMR) peptide from HIV-1 Nef and at least one Clusterin (Clu)-binding peptide (Clu-BP). Pharmaceutical compositions comprising these peptides alone or in synergistic combinations with other active agents in methods for treating cancers and/or infectious diseases are further provided herein.
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公开(公告)号：US20180265822A1
公开(公告)日：2018-09-20
申请号：US15984910
申请日：2018-05-21
CPC分类号： C11D11/0088 , A01N25/02 , A01N25/26 , C11D3/43 , C11D3/48 , C11D17/0013 , C11D17/0039 , A01N25/04
摘要： A method for formulating a composition contains the step of coating a granular absorbent material with a coating agent to produce a coated absorbent material and mixing the coated absorbent material with a sanitation agent, wherein the coated absorbent material absorbs the sanitation agent to form the liquid loading composition. Liquid-loading compositions that can absorb liquids in many applications, including clean-up and farming, are also disclosed.
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公开(公告)号：US20180103885A1
公开(公告)日：2018-04-19
申请号：US15295489
申请日：2016-10-17
发明人： Glenda WRENN
CPC分类号： A61B5/16 , A61B5/0022 , A61B5/4088 , A61B5/6888 , A61B5/742 , A61B5/746 , G16H10/20 , G16H10/60 , G16H20/70 , G16H50/30
摘要： A method and system for assessing the mental state or behavioral disorder of a subject is disclosed. The system includes a display, an input device, a processor, a database and matrix for converting the responses to one or more assessment scores. The disclosure also relates to a method for treating a behavioral disorder using the method and a system described herein.
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公开(公告)号：US09867795B2
公开(公告)日：2018-01-16
申请号：US15357731
申请日：2016-11-21
申请人： The UAB Research Foundation , State of Oregon Acting By and Through the Board of Education on Behalf of the University of Oregon , University College Cardiff Consultants Limited , Morehouse School of Medicine, Inc.
发明人： Bruce A. Freeman , Francisco Schopfer , Valerie O'Donnell , Paul Baker , Yuqing E. Chen , Bruce Branchaud
IPC分类号： A61K31/70 , A61K31/201 , A61K45/06
CPC分类号： A61K31/201 , A61K31/202 , A61K31/21 , A61K31/575 , A61K45/06 , C07B43/02 , C07C205/03 , C07C205/50 , C07C205/51
摘要： Described herein are nitrated lipids and methods of making and using the nitrated lipids.
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公开(公告)号：US20170299591A2
公开(公告)日：2017-10-19
申请号：US15377054
申请日：2016-12-13
发明人： Gale W. NEWMAN , Sam ANYANWU
IPC分类号： G01N33/569 , C12Q1/70
CPC分类号： G01N33/56988 , C12Q1/70 , C12Q1/703 , C12Q1/706 , C12Q1/707 , G01N1/40 , G01N33/493 , G01N33/56983 , G01N33/576 , G01N33/6893 , G01N2333/02 , G01N2333/10 , G01N2333/161 , G01N2333/162 , G01N2333/163 , G01N2333/186 , G01N2800/347 , G01N2800/52 , G01N2800/56
摘要： A method for diagnosing hepatitis virus infection or a hepatitis disease condition in a subject based on hepatitis virus-associated biomarkers present on exosomes in a bodily fluid sample from the subject is disclosed. Also disclosed are a method for monitoring the course of a hepatitis virus infection or a hepatitis-diseases condition in a subject and a method for monitoring effectiveness of treatment to a subject with an anti-hepatitis virus agent based on hepatitis virus-associated biomarkers present on exosomes in bodily fluid samples from the subject, as well as a kit for diagnosing hepatitis virus infection and/or a hepatitis disease condition in a subject based on hepatitis virus-associated biomarkers on exosomes in bodily fluid samples from the subject.
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公开(公告)号：US20170168052A1
公开(公告)日：2017-06-15
申请号：US15377054
申请日：2016-12-13
发明人： Gale W. NEWMAN , Sam ANYANWU
IPC分类号： G01N33/569 , C12Q1/70
CPC分类号： G01N33/56988 , C12Q1/70 , C12Q1/703 , C12Q1/706 , C12Q1/707 , G01N1/40 , G01N33/493 , G01N33/56983 , G01N33/576 , G01N33/6893 , G01N2333/02 , G01N2333/10 , G01N2333/161 , G01N2333/162 , G01N2333/163 , G01N2333/186 , G01N2800/347 , G01N2800/52 , G01N2800/56 , Y02A50/54
摘要： A method for diagnosing hepatitis virus infection or a hepatitis disease condition in a subject based on hepatitis virus-associated biomarkers present on exosomes in a bodily fluid sample from the subject is disclosed. Also disclosed are a method for monitoring the course of a hepatitis virus infection or a hepatitis disease condition in a subject and a method for monitoring effectiveness of treatment to a subject with an anti-hepatitis virus agent based on hepatitis virus-associated biomarkers present on exosomes in bodily fluid samples from the subject, as well as a kit for diagnosing hepatitis virus infection and/or a hepatitis disease condition in a subject based on hepatitis virus-associated biomarkers on exosomes in bodily fluid samples from the subject.
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公开(公告)号：US09522156B2
公开(公告)日：2016-12-20
申请号：US15040376
申请日：2016-02-10
申请人： The UAB Research Foundation , State of Oregon Acting By and Through the Board of Education on Behalf of the University of Oregon , University College Cardiff Consultants Limited , Morehouse School of Medicine, Inc.
发明人： Bruce A. Freeman , Francisco Schopfer , Valerie O'Donnell , Paul Baker , Yuqing E. Chen , Bruce Branchaud
IPC分类号： C07C227/00 , C07C229/00 , A61K31/575 , A61K31/21 , C07B43/02 , C07C205/50 , C07C205/51 , C07C205/03 , A61K31/201 , A61K31/202 , A61K45/06
CPC分类号： A61K31/201 , A61K31/202 , A61K31/21 , A61K31/575 , A61K45/06 , C07B43/02 , C07C205/03 , C07C205/50 , C07C205/51
摘要： Described herein are nitrated lipids and methods of making and using the nitrated lipids.
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