Abstract:
The invention is directed to compositions of mutated binding proteins containing reporter groups, analyte biosensor devices derived therefrom, and their use as analyte biosensors both in vitro and in vivo.
Abstract:
The present invention includes systems and methods for customization of internet applications. Multiple levels of customization are applied to both static and functional aspects of user interface elements including, for example, tab-order, tab-over, immediate access keys, and hotkeys. Customization is also achieved with respect to searching over multiple user interfaces, presentation of information on a user interface, and the interaction model used by the internet application. Customization is enabled on any client supporting standard browser functionality.
Abstract:
A golf club head has a cavity for receiving a face insert. A first face insert, which is disposed in the cavity, has a front surface that is contoured. A second face insert composed of multiple rod elements is disposed in the cavity on top of the first face insert so that the rod elements are supported by the contoured front surface of the first face insert. Because the first face insert supporting the rod elements is contoured, the individual rod elements are of different lengths and, therefore, exhibit different dynamic responses when striking a golf ball, even when the rod elements are made of the same material.
Abstract:
The invention provides methods of treatment using retro-inverso peptides derived from interleukin-3 (IL-3) having between 12 and about 40 amino acids and including the sequence that is retro-inverso with respect to SEQ ID NO: 1. These peptides of the invention have the same activity as native IL-3 and also have neurotrophic activity. The peptides of the invention are also less susceptible to proteolytic degradation in vivo because of their D-amino acid linkage.
Abstract translation:本发明提供了使用衍生自具有12至约40个氨基酸的白细胞介素-3(IL-3)的逆转换肽并包括相对于SEQ ID NO:1的反向逆转的序列进行治疗的方法。 本发明具有与天然IL-3相同的活性,并且具有神经营养活性。 由于它们的D-氨基酸连接,本发明的肽也不太容易在体内蛋白水解降解。
Abstract:
The invention provides methods of treatment using retro-inverso peptides derived from leukemia inhibitory factor (LIF) having between 18 and about 40 amino acids and including the sequence that is retro-inverso with respect to SEQ ID NO: 1. The peptides of the invention have the same activity as native LIF and also have neurotrophic activity. The peptides of the invention are also less susceptible to proteolytic degradation in vivo because of their D-amino acid linkage.
Abstract translation:本发明提供了使用衍生自具有18至约40个氨基酸的白血病抑制因子(LIF)的逆转换肽的治疗方法,并且包括相对于SEQ ID NO:1的反向逆转序列。本发明的肽 具有与天然LIF相同的活性,并具有神经营养活性。 由于它们的D-氨基酸连接,本发明的肽也不太容易在体内蛋白水解降解。
Abstract:
Methods and apparatus to extract audio codes are disclosed. An example method includes receiving signals on a plurality of channels and ranking the signals based on at least one characteristic of the signals. A first channel from the plurality of channels is selected based upon the ranking of the signals. The example method further include determining whether a first signal on the first channel includes at least one code and extracting the at least one code from the first signal when the first signal includes the at least one code.
Abstract:
Methods and apparatus for monitoring video games are disclosed. An example method disclosed herein comprises monitoring game content corresponding to a game medium played by a game console, processing the game content to determine a set of metering data, and cross-referencing the set of metering data with a set of reference data corresponding to a set of known games.
Abstract:
In one example, a system for an engine having an intake system and an exhaust system is described. The system comprises: an airflow sensor coupled to the intake system; an air pump having at least an inlet side and an outlet side, said inlet side having a first coupling to the intake system downstream of said airflow sensor, said outlet side having a second coupling to the exhaust system; and a controller coupled to the engine, said controller, during operation, identifying whether degradation has occurred to at least one of said first and second couplings, and providing an indication of said identified degradation. Various other examples are also disclosed.
Abstract:
A method of classifying a document includes providing a plurality of classifier engines and classifying the document using output from one or more of the classifier engines based on a comparison of one or more metrics for each classifier engine. In another embodiment, a method of classifying a document comprises providing a plurality of classifier engines and determining one or more metrics for each classifier engine. These metrics are used to determine how to use the classifier engines to classify the document, and the document is classified accordingly. A further embodiment includes a document classifier utilizing a plurality of classifier engines. In yet another embodiment, a computer-readable medium contains instructions for controlling a computer system to perform a method of using a plurality of classifier engines to classify a document.
Abstract:
A golf club head has a face insert that is supported from beneath by a substrate composed of a plurality of elongate rod elements arranged in a parallel closely packed array. Because the face insert is made of a single material, the resiliency of the face insert itself does not vary across the front surface of the face insert; however, the effective resiliency of the face insert may be varied by varying the resiliency of the substrate. This is accomplished by selecting different materials and/or different overall lengths for the rod elements that comprise the substrate. Use of a substrate comprising a plurality of rod elements permits the effective resiliency of the face insert to be varied without varying the face material.