公开(公告)号：US20080281337A1

公开(公告)日：2008-11-13

申请号：US12079250

申请日：2008-03-25

申请人： Stefan J. M Kraemer ,  John M. Adams ,  Stephen T. Vincent

发明人： Stefan J. M Kraemer ,  John M. Adams ,  Stephen T. Vincent

IPC分类号： A61B17/10

CPC分类号： A61B17/068 ,  A61B17/00234 ,  A61B17/0644 ,  A61B17/07207 ,  A61B2017/003 ,  A61B2017/00827 ,  A61B2017/00867 ,  A61B2017/07214 ,  A61B2017/2905 ,  A61B2017/2926 ,  A61B2017/306

摘要： The invention provides a device, assembly, and method for transoral endoscopic restoration of a gastroesophageal flap valve. The invention also provides a self-steering and self-closing tissue fixation device for tissue fixation, and an invaginator device for gripping and maneuvering tissue. The restoration device includes a longitudinal member arranged for transoral placement into a stomach, a tissue shaper carried on the longitudinal member that causes stomach tissue to assume a shape related to a gastroesophageal flap, and a tissue fixation device that maintains the shaped stomach tissue in a shape approximating a gastroesophageal flap. The tissue shaper may include a mold. The device may include the invaginator device for gripping and maneuvering esophageal tissue to aid restoration of the gastroesophageal flap, and may include the tissue fixation device.

公开(公告)号：US20080058718A1

公开(公告)日：2008-03-06

申请号：US11516812

申请日：2006-09-06

申请人： John M. Adams ,  Clifton A. Alferness ,  Daniel Hawkins

发明人： John M. Adams ,  Clifton A. Alferness ,  Daniel Hawkins

IPC分类号： A61M37/00

CPC分类号： A61M5/152 ,  A61M5/14248

摘要： A wearable infusion device delivers a liquid medicant to a patient. The infusion device comprises a base that contacts a patient's skin and a reservoir arranged to be filled with a liquid medicant to be delivered beneath a patient's skin. The reservoir has an outlet through which the medicant flows. The infusion device further comprises a flexible conduit communicating with the outlet of the reservoir, a pump that causes the medicant to flow down the conduit, an actuator that performs a function related to the operation of the device, and an enable mechanism that enables the actuator in response to the filling of the reservoir with the liquid medicant.

摘要翻译： 可戴式输液装置将液体药剂递送给患者。 输液装置包括接触患者皮肤的基部和布置成填充有待在患者皮肤下方递送的液体药物的储存器。 储存器具有药物流过的出口。 输液装置还包括与储存器的出口连通的柔性导管，使得药剂沿着管道流下的泵，执行与装置的操作有关的功能的致动器，以及启动机构，其使致动器 响应于用液体药物填充储存器。

公开(公告)号：US20070282269A1

公开(公告)日：2007-12-06

申请号：US11641596

申请日：2006-12-18

申请人： Brett J. Carter ,  Clifton A. Alferness ,  John M. Adams ,  Daniel Hawkins

发明人： Brett J. Carter ,  Clifton A. Alferness ,  John M. Adams ,  Daniel Hawkins

IPC分类号： A61M5/162

CPC分类号： A61M5/14248 ,  A61M5/152 ,  A61M2005/14252 ,  A61M2005/14256 ,  A61M2005/1585 ,  A61M2209/045

摘要： An infusion system comprises a disposable wearable infusion device having a body arranged to be adhered to a patient's skin and a reservoir for holding a liquid medicant to be infused into the patient. The infusion system further includes a cannula driver arranged to be detachably joined with the infusion device. The cannula driver includes a cannula and is arranged to drive the cannula into a deployed position extending from the infusion device to beneath the patient's skin.

摘要翻译： 输液系统包括一次性穿戴式输注装置，其具有被布置成粘附到患者皮肤上的主体和用于保持待注入患者体内的液体药物的储存器。 输液系统还包括布置成可与输液装置可拆卸地连接的套管驱动器。 插管驱动器包括插管并且被布置成将插管驱动到从输注装置延伸到患者皮肤下方的展开位置。

公开(公告)号：US06908478B2

公开(公告)日：2005-06-21

申请号：US10011867

申请日：2001-12-05

申请人： Clifton A. Alferness ,  John M. Adams ,  Mark L. Mathis ,  David G. Reuter

发明人： Clifton A. Alferness ,  John M. Adams ,  Mark L. Mathis ,  David G. Reuter

IPC分类号： A61F2/24 ,  A61F2/06

CPC分类号： A61F2/2451 ,  A61F2/2466

摘要： A device, system, and method effects mitral valve annulus geometry of a heart. The device includes a first anchor configured to be positioned within and fixed to the coronary sinus of the heart adjacent the mitral valve annulus within the heart. A cable is fixed to the first anchor and extends proximately therefrom and slidingly through a second anchor which is positioned and fixed in the heart proximal to the first anchor. A lock locks the cable to the second anchor when tension is applied to the cable for effecting the mitral valve annulus geometry.

摘要翻译： 一种装置，系统和方法影响心脏的二尖瓣环形几何。 该装置包括构造成定位在心脏内邻近二尖瓣环的心脏的冠状窦内并固定到其的冠状窦的第一锚。 电缆固定到第一锚固件并且从其向近侧延伸并且滑动地穿过定位并固定在靠近第一锚固件的心脏中的第二锚固件。 当拉索施加到电缆以实现二尖瓣环形几何时，锁将电缆锁定到第二锚定器。

公开(公告)号：US06347249B1

公开(公告)日：2002-02-12

申请号：US09553911

申请日：2000-04-20

申请人： Jaeho Kim ,  Phillip D. Foshee, Jr. ,  John M. Adams

发明人： Jaeho Kim ,  Phillip D. Foshee, Jr. ,  John M. Adams

IPC分类号： A61N137

CPC分类号： A61N1/3704

摘要： A system and method are provided for detecting dislodgment of a right atrial endocardial lead implanted within a heart right atrium wherein the lead includes an electrode. Heart activity of the right ventricle of the heart and heart activity with the endocardial lead electrode are sensed during a time period. The sensed heart activity is stored in memory. The stored heart activity is analyzed to establish a first time window from the sensed ventricle activity and a second time window spaced from and preceding the first time window. The heart activity sensed with the endocardial lead electrode during the first time window is then compared to the heart activity sensed with the endocardial lead electrode during the second time window. In another embodiment, whenever heart activity is sensed with the atrial endocardial lead during the first time period, the atrial endocardial lead is considered dislodged.

摘要翻译： 提供了一种系统和方法，用于检测植入在心脏右心房内的右心房心内膜的脱落，其中所述引线包括电极。 在一段时间内，感测心脏和心脏活动的心脏心脏心脏活动与心内膜引导电极的心脏活动。 所感知的心脏活动被存储在存储器中。 分析存储的心脏活动以从感测到的心室活动建立第一时间窗口，并且与第一时间窗口间隔开并在第一时间窗口之前的第二时间窗口。 然后在第一时间窗口期间用心内膜引导电极感测的心脏活动与在第二时间窗口期间用心内膜引导电极感测的心脏活动进行比较。 在另一个实施方案中，每当在第一时间段内用心房心内膜的心脏感测心脏活动时，心房心内膜的铅被认为是脱出的。

公开(公告)号：US5878752A

公开(公告)日：1999-03-09

申请号：US756223

申请日：1996-11-25

申请人： John M. Adams ,  William J. Crowe ,  Grier S. Fleischhauer ,  Jay A. Fournier ,  Mohammad R. Hajaligol ,  Willie G. Houck, Jr. ,  Donald B. Losee ,  Constance H. Morgan ,  John D. Naworal ,  H. Neal Nunnally ,  John B. Paine, III ,  Wynn R. Raymond ,  Robert L. Ripley ,  Jeffrey I. Seeman ,  Francis M. Sprinkel ,  Michael L. Watkins

发明人： John M. Adams ,  William J. Crowe ,  Grier S. Fleischhauer ,  Jay A. Fournier ,  Mohammad R. Hajaligol ,  Willie G. Houck, Jr. ,  Donald B. Losee ,  Constance H. Morgan ,  John D. Naworal ,  H. Neal Nunnally ,  John B. Paine, III ,  Wynn R. Raymond ,  Robert L. Ripley ,  Jeffrey I. Seeman ,  Francis M. Sprinkel ,  Michael L. Watkins

IPC分类号： A24F47/00

CPC分类号： A24F47/008

摘要： Methods and apparatuses for cleaning an electrical lighter are provided. A sleeve, e.g., ceramic or metal, surrounds the heater fixture, and a resistive heating element is in thermal proximity with the sleeve. The resistive heating element is either a dedicated element or the cigarette heating elements. The sleeve serves as a aerosol barrier and condensate accumulator to protect other components. Periodically, e.g., substantially contemporaneously with a battery recharge, the heating element is activated to thermally liberate condensates deposited on the sleeve during smoking and also heats, and thereby cleans, other components. Also, a cleaning element is optionally inserted into the cigarette receptacle of the electrical lighter or placed at the exit thereof to absorb, attract and/or catalytically break down the thermally liberated condensates. The sleeve also directs a desired flow path for drawn air within an electrical lighter toward the cigarette.

摘要翻译： 提供了清洁电打火机的方法和设备。 诸如陶瓷或金属的套管围绕加热器固定装置，电阻加热元件与套筒热接近。 电阻加热元件是专用元件或香烟加热元件。 套筒用作气溶胶屏障和冷凝液蓄能器，以保护其他部件。 周期性地，例如基本同时具有电池再充电，加热元件被激活以在吸烟期间热释放沉积在套筒上的冷凝物，并且还加热，从而清洁其它组分。 此外，清洁元件可选地插入电动打火机的香烟容器中或放置在其出口处以吸收，吸引和/或催化地分解热释放的冷凝物。 套筒还引导用于打火机内的抽吸空气的所需流路朝向香烟。

公开(公告)号：US5814081A

公开(公告)日：1998-09-29

申请号：US835169

申请日：1997-04-07

申请人： Gregory M. Ayers ,  John M. Adams

发明人： Gregory M. Ayers ,  John M. Adams

IPC分类号： A61N1/39

CPC分类号： A61N1/3956 ,  A61N1/395

摘要： An implantable atrial defibrillator includes a lead system having a plurality of electrodes to deliver a cardioverting pulse to atria of a heart, for sensing A waves of the heart, and for sensing R waves of the heart. A first detector detects the A waves sensed by the lead system and a second detector detects the R waves sensed by the lead system. An inhibit stage defines an inhibit time period responsive to each detected R wave and an output provides the cardioverting pulse to the lead system responsive to an A wave being detected. The inhibit stage precludes provision of the cardioverting pulse during each inhibit time period.

摘要翻译： 可植入心房除颤器包括引导系统，该引导系统具有多个电极，用于将心律转换脉冲输送到心脏的心房，用于感测心脏的波浪，并用于感测心脏的R波。 第一检测器检测由引导系统感测的A波，第二检测器检测由引导系统感测的R波。 禁止级定义响应于每个检测到的R波的禁止时间周期，并且输出响应于检测到的A波而将引导系统提供心跳转换脉冲。 禁止阶段排除了在每个禁止时间段期间提供的复律脉冲。

公开(公告)号：US5777987A

公开(公告)日：1998-07-07

申请号：US580947

申请日：1995-12-29

申请人： John M. Adams ,  Timothy E. Hoglund ,  Stephen M. Johnson ,  Mark A. Reber ,  David M. Weber

发明人： John M. Adams ,  Timothy E. Hoglund ,  Stephen M. Johnson ,  Mark A. Reber ,  David M. Weber

IPC分类号： H04L29/02 ,  H04L12/56 ,  H04J3/00

CPC分类号： H04L47/30 ,  H04L47/10 ,  H04L47/26

摘要： A method and associated apparatus for using a primary FIFO and one or more secondary FIFOs in parallel to simplify flow control and routing in packet communication operations wherein at least one FIFO (buffer) is associated with each of a plurality of receiving nodes or components within a receiving node. The present invention applies received packets simultaneously to a primary FIFO and to all associated secondary FIFOs in the receiver of a packet communications link. After receipt of a packet, the packet is removed from any secondary FIFOs which correspond to receiver nodes or components to which the packet was not routed. For all receiving nodes or components to which the packet was routed, if the packet was stored in each associated secondary FIFO without overflow, then the packet is also purged from the primary FIFO. If any secondary FIFO overflowed by storage of the received packet, then the packet is purged from the overflowed FIFO and the packet remains stored in the primary FIFO for further processing. Flow control signals are generated and applied to the transmitting source as required in accordance with the status of the primary FIFO. The secondary FIFOs are not directly relevant to flow control logic. The receiving component corresponding to each secondary FIFO locates the next packet for processing by inspecting the associated secondary FIFO as well as the primary FIFO if the secondary FIFO overflowed. These methods and apparatus simplify flow control and routing control in packetized communication receivers.

摘要翻译： 一种用于并行地使用主FIFO和一个或多个辅助FIFO以简化在分组通信操作中的流控制和路由的方法和相关联的装置，其中至少一个FIFO（缓冲器）与多个接收节点中的每一个相关联， 接收节点。 本发明将接收到的分组同时应用于主FIFO和分组通信链路的接收机中的所有相关联的辅助FIFO。 在接收到分组之后，从与分组未被路由到的接收机节点或组件对应的任何辅助FIFO中移除分组。 对于分组路由到的所有接收节点或组件，如果分组存储在每个相关联的辅助FIFO中，而不会溢出，则该分组也从主FIFO中清除。 如果任何辅助FIFO通过存储接收的分组溢出，则从溢出的FIFO中清除分组，并且分组保持存储在主FIFO中用于进一步处理。 根据主FIFO的状态，根据需要生成流量控制信号并将其应用于发送源。 二级FIFO与流量控制逻辑不直接相关。 对应于每个辅助FIFO的接收组件通过检查相关联的辅助FIFO以及主FIFO溢出时定位下一个数据包进行处理。 这些方法和装置简化了分组通信接收机中的流量控制和路由控制。

公开(公告)号：US5692526A

公开(公告)日：1997-12-02

申请号：US485176

申请日：1995-06-07

申请人： John M. Adams ,  Mary Ellen Counts ,  Grier S. Fleischhauer ,  Kenneth S. Houghton ,  Willie G. Houck, Jr. ,  Billy J. Keen, Jr. ,  Wesley G. Sanderson ,  Susan E. Wrenn

发明人： John M. Adams ,  Mary Ellen Counts ,  Grier S. Fleischhauer ,  Kenneth S. Houghton ,  Willie G. Houck, Jr. ,  Billy J. Keen, Jr. ,  Wesley G. Sanderson ,  Susan E. Wrenn

IPC分类号： A24F47/00 ,  A24D1/04

CPC分类号： A24F47/008

摘要： A novel cigarette of an electrical cigarette system and method of making same, the cigarette comprising a tubular tobacco web and a plug disposed within said tubular tobacco web which provides a structural connection that remains intact after a smoking of the cigarette. The disclosure includes a double-belled plug extending between a free end and a tipped end of a tobacco rod, or in the alternative, a column of tobacco with higher and lower density segments. The disclosure includes a method comprising the steps of producing a continuous plug, passing same through a die, overwrapping the rod with tobacco mat and overwrap, and severing the rod.

摘要翻译： 一种电子香烟系统的新型香烟及其制造方法，该香烟包括管状烟草纤维网和设置在所述管状烟草纤维网内的插塞，其提供在吸烟之后保持完整的结构连接。 本公开包括在烟丝杆的自由端和尖端之间延伸的双钟形塞子，或者替代地，具有较高和较低密度段的烟草柱。 本公开包括一种方法，其包括以下步骤：制造连续插塞，使其穿过模具，用烟草垫包裹杆和外包裹物，以及切断杆。

公开(公告)号：US5350404A

公开(公告)日：1994-09-27

申请号：US130308

申请日：1993-10-01

申请人： John M. Adams ,  Clifton A. Alferness ,  Paul E. Kreyenhagen

发明人： John M. Adams ,  Clifton A. Alferness ,  Paul E. Kreyenhagen

IPC分类号： A61N1/05 ,  A61N1/372 ,  A61N1/39

CPC分类号： A61N1/3918 ,  A61N1/056 ,  A61N1/0563 ,  A61N1/3956 ,  A61N1/3962 ,  A61N1/395 ,  A61N1/3987 ,  A61N2001/0585

摘要： An implantable atrial defibrillator provides a pulse of defibrillating electrical energy to the atria of the heart in synchronism with sensed R waves in response to non-coincident sensing of an R wave at first and second areas of the heart. The defibrillating pulse is provided after a predetermined number of consecutive R waves are non-coincidently sensed to assure reliable synchronization. The atrial defibrillator is also operational in a marker mode wherein a number of synchronization marker pulses are delivered to the heart for detection on an externally generated electrocardiogram. The atrial fibrillation detector of the defibrillator is normally disabled and is activated when the sensed ventricular activity indicates a probability of atrial fibrillation to conserve a depletable power source. A plurality of lead systems are also described for use with the atrial defibrillator which reduce the quantity of electrical energy required to defibrillate the heart and ensure that the delivered atrial defibrillating electrical energy is substantially confined to the atria of the heart.

摘要翻译： 可植入心房除颤器响应于在心脏的第一和第二区域处的R波的不一致的感测，与感测到的R波同步地向心脏的心房提供除颤电脉冲。 在不一致地感测到预定数量的连续R波之后提供除颤脉冲，以确保可靠的同步。 心房除颤器还可以在标记模式中操作，其中多个同步标记脉冲被传送到心脏以便在外部产生的心电图上进行检测。 除颤器的心房颤动检测器通常被禁用，并且当感测到的心室活动指示心房颤动的概率以节省可消耗的电源时被激活。 还描述了与心房除颤器一起使用的多个引导系统，其减少了除颤心脏所需的电能的量，并确保输送的心房除颤电能基本上限于心脏的心房。