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公开(公告)号：US5792172A
公开(公告)日：1998-08-11
申请号：US774131
申请日：1996-12-23
CPC分类号： A61M25/1038 , A61F2/958 , A61F2/90 , A61F2250/0098 , A61M2025/1004 , A61M25/1002
摘要： The present invention utilizes a balloon with three or more folds to more evenly distribute the frictional forces on the inside of a stent during stent deployment thus improving the uniformity of stent cell expansion. Ideally one would like to have the same number of balloon folds as the number of stent cells distributed circumferentially around the stent. Matching the number of balloon folds to the number of cells of each cylindrical segment of the stent provides better size uniformity for the stent cells after they are expanded against the wall or other vessel within a human body.
摘要翻译： 本发明利用具有三个或更多个折叠的气囊来在支架展开期间更均匀地将摩擦力分布在支架的内侧，从而改善支架细胞扩张的均匀性。 理想情况下，希望具有与支架周向分布的支架细胞数目相同数量的气球折叠。 将支架细胞的数量与支架的每个圆柱形段的细胞数相匹配，在支架细胞相对于人体内的壁或其他血管扩张之后，提供更好的尺寸均匀性。
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公开(公告)号：US5792144A
公开(公告)日：1998-08-11
申请号：US828662
申请日：1997-03-31
CPC分类号： A61F2/958
摘要： The present invention is a stent delivery catheter system for placing a stent within a stenosis in a vessel of a human body. The stent delivery catheter system utilizes a slideable sheath with a thin-walled distal portion that is situated coaxially over a stent that is placed onto a balloon located at the distal portion of a balloon angioplasty catheter. The distal end of a central portion of the sheath has an interior shoulder which is capable of exerting a distally directed push force on the balloon angioplasty catheter at a point that is just proximal to the stent. This push force is then transferred through the non-deployed stent to a gradually tapered, highly flexible, lubricity coated distal tip of the balloon angioplasty catheter. The structure of a continuous outer surface extending backward from the distal tip and onto the distal section of the sheath, plus the lubricity coating of the outer surfaces of the distal tip and the sheath, plus the increased stent delivery catheter system pushability provided by the sheath and the stent itself makes it possible for the stent delivery catheter system to be pushed through even very tight stenoses.
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113.发明授权
公开(公告)号：US5639274A
公开(公告)日：1997-06-17
申请号：US458471
申请日：1995-06-02
CPC分类号： A61F2/958 , A61M2025/0183 , A61M25/10
摘要： This invention is directed to an integrated catheter system (60) including a stent catheter (65) and a balloon angioplasty catheter (20). The balloon angioplasty catheter (20) has an inflatable balloon (23) mounted near the catheter's distal end which is initially used for dilation of a vessel at a low balloon pressure to partially inflate the balloon (23). The stent catheter (65) contains a stent (15) within a stent containment cavity (69) and the stent (15) is displaced over the balloon (23). The stent (15) is held in place over the partially inflated balloon (23) and an outer tube (62) of the stent catheter (65) is pulled back. The stent (15) is deployed and the balloon (23) is reinflated to a higher pressure to embed the stent (15) into the wall of the vessel.
摘要翻译： 本发明涉及一种包括支架导管（65）和球囊血管成形术导管（20）的集成导管系统（60）。 球囊血管成形术导管（20）具有安装在导管远端附近的可膨胀气球（23），其最初用于在低气囊压力下扩张容器以部分地使气囊（23）膨胀。 支架导管（65）在支架容纳腔（69）内包含支架（15），支架（15）在气囊（23）上移位。 将支架（15）保持在部分充气的球囊（23）上的适当位置，支架导管（65）的外管（62）被拉回。 支架（15）展开，并且气球（23）被再次膨胀到更高的压力以将支架（15）嵌入容器的壁中。
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114.发明授权Method for accessing the coronary arteries from the radial or brachial artery in the arm 失效从手臂的桡动脉或肱动脉进入冠状动脉的方法
公开(公告)号：US5492530A
公开(公告)日：1996-02-20
申请号：US384277
申请日：1995-02-02
IPC分类号： A61M25/06 , A61M25/088 , A61M31/00
CPC分类号： A61M25/0662
摘要： The present invention is a method for using an improved guiding catheter that eliminates the need for an introducer sheath or a separate Tuohy-Borst "Y" adaptor, thus reducing the time and expense for performing artery opening procedures. Furthermore, the guiding catheter with straightening dilator as described herein allows the hole in the wall of the femoral artery in the groin, or even more advantageously, the radial artery in the arm to be approximately 2 French sizes smaller in diameter as compared to the hole that would be created if an introducer sheath is also used. The advantages of the present invention are accomplished by utilizing a guiding catheter with a dilator that has a stiffened and/or curved distal section that can be used to straighten the distal section of the guiding catheter as it is advanced through the arterial system. The guiding catheter plus dilator can then be used in a manner similar to an introducer sheath to percutaneously enter the artery by being advanced over a previously placed guide wire. Once the distal ends of the dilator and the guiding catheter are placed near the ostium of the coronary artery, the dilator and guide wire are withdrawn which allows the guiding catheter to assume its normal bent shape (e.g., a Judkin's bend) near its distal end. The cardiologist can then, by well known techniques, place the guiding catheter's distal end in the ostium of a coronary artery. Any of several well known procedures can then be performed including angiography, balloon angioplasty, atherectomy or stent placement.
摘要翻译： 本发明是一种使用改进的引导导管的方法，其不需要导引鞘或单独的Tuohy-Borst“Y”适配器，因此减少了执行动脉开放程序的时间和费用。 此外，如本文所述的具有矫直扩张器的引导导管允许在腹股沟的股动脉壁中的孔，或甚至更有利地，臂中的桡动脉与孔相比为直径更小的约2个法国尺寸 如果还使用导引鞘，将会产生这种情况。 本发明的优点是通过利用具有扩张器的引导导管实现的，所述扩张器具有加强和/或弯曲的远端部分，该远端部分可用于在引导导管的远端部分通过动脉系统前进时拉直。 引导导管加扩张器然后可以以类似于导引鞘的方式使用，以通过在先前放置的导丝上推进来经皮进入动脉。 一旦扩张器和引导导管的远端放置在冠状动脉的口处附近，扩张器和引导线被拉出，允许引导导管在其远端附近呈现其正常的弯曲形状（例如，Judkin的弯曲） 。 然后，通过众所周知的技术，心脏病专家将引导导管的远端放置在冠状动脉的口中。 然后可以执行几种众所周知的方法中的任何一种，包括血管造影，球囊血管成形术，粥样斑块切除术或支架放置。
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公开(公告)号：US5295969A
公开(公告)日：1994-03-22
申请号：US874366
申请日：1992-04-27
CPC分类号： A61M25/0693 , A61M39/0606 , A61M2039/062 , A61M2039/0633 , A61M2039/0666 , Y10S604/90
摘要： The present invention is a means for accessing blood vessels for the insertion of a guide wire while preventing the free release of blood. Specifically, a hollow, thin-walled metal tube typically having a sharp point at its distal end is joined at its proximal end to a transparent viewing section. The viewing section has a distal narrow lumen and a proximal chamber which has a cap at its proximal end. The cap encloses a pressure sealing means through which a guide wire can be passed. After the distal end of the metal tube is placed in an artery, blood will rush through the metal tube and into the viewing section. The air in the air-tight proximal chamber will alternatively be compressed between diastolic and systolic blood pressure. Feedback to the operator that the distal end of the metal tube is properly placed within an artery can be achieved by observing the reciprocating pulsatile motion of the blood column within the distal narrow lumen of the viewing section. When the proper pulsatile motion is observed, a guide wire can be passed through the sealing means in the cap, through the viewing section, through the metal tube and finally the guide wire will enter the lumen of the artery.
摘要翻译： 本发明是一种用于在防止血液自由释放的同时插入导丝的血管。 具体来说，通常在其远端具有尖锐点的中空薄壁金属管在其近端处连接到透明观察部分。 观察部分具有远端狭窄的管腔和近端腔室，其近端具有帽盖。 盖子包围压力密封装置，引导线可以通过该压力密封装置通过。 在金属管的远端放置在动脉中之后，血液将通过金属管冲入观察部分。 空气密封近端腔室中的空气可以在舒张压和收缩压之间被压缩。 通过观察在观察部分的远端狭窄管腔内的血柱的往复式脉动运动，可以对操作者反馈金属管的远端适当地放置在动脉内。 当观察到适当的脉动运动时，导丝可以穿过盖中的密封装置，通过观察部分穿过金属管，最后引导线将进入动脉的内腔。
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公开(公告)号：US09204988B1
公开(公告)日：2015-12-08
申请号：US14468881
申请日：2014-08-26
申请人： Robert E. Fischell
发明人： Robert E. Fischell
IPC分类号： A61F5/08
CPC分类号： A61F5/08
摘要： A nasal strip having a non-adhesive central portion situated between two adhesive end sections of the nasal strip. In one example, a thin plastic covering over the adhesive surface of the central portion of the nasal strip provides advantages of more torque obtained to open the nasal passageways, less discomfort on removal of the nasal strip, easier placement of the nasal strip onto the nose and less area of the skin on the nose that can be irritated by the adhesive interior surface of the nasal strip.
摘要翻译： 鼻带，其具有位于鼻带的两个粘合剂端部之间的非粘性中心部分。 在一个示例中，覆盖在鼻带中心部分的粘合剂表面上的薄塑料提供了获得打开鼻通道的更多扭矩的优点，在去除鼻带时较少的不适，更容易将鼻带放置在鼻子上 并且鼻部皮肤的面积可以被鼻带的粘合剂内表面刺激。
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公开(公告)号：US20080290097A1
公开(公告)日：2008-11-27
申请号：US11805299
申请日：2007-05-24
申请人： Robert E. Fischell , Daniel Heifetz
发明人： Robert E. Fischell , Daniel Heifetz
IPC分类号： A47G19/02
CPC分类号： A47G19/02
摘要： The present invention is a uniquely shaped divided bowl that has two separated sections: 1) a cereal section, and 2) a milk and fruit section. These sections are approximately the same size. The consumer places the dry cereal into the cereal section and then places milk and fruit into the milk and fruit section. It should be understood that the consumer might chose to have only milk in the milk and fruit section. An important feature of the design of the milk and fruit section is a groove at its bottom surface into which the last of the milk and fruit goes so that the last bites can be consumed without titling the bowl.
摘要翻译： 本发明是一种独特形状的分开的碗，其具有两个分开的部分：1）谷物部分，和2）牛奶和水果部分。 这些部分的大小大致相同。 消费者将干燥谷物放入谷物部分，然后将牛奶和水果放入牛奶和水果部分。 应该理解，消费者可能选择在牛奶和水果部分只有牛奶。 牛奶和水果部分的设计的一个重要特征是在其底部表面上的凹槽，最后的牛奶和水果进入该凹槽，使得最后的叮咬可以被消耗而不需要压头碗。
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公开(公告)号：US20080058637A1
公开(公告)日：2008-03-06
申请号：US11502960
申请日：2006-08-14
IPC分类号： A61B5/05
CPC分类号： A61B5/06 , A61B90/39 , A61B2090/3908 , A61B2090/3954 , A61B2090/3987
摘要： Disclosed is a system for placing an elongated permanent magnet into a volume of tissue within a human body that is suspected of being cancerous. The magnet's position is then detected by a magnet locating system that is used by a surgeon to find and remove the suspected tissue volume including a margin of tissue to assure that any and all cancer cells have been excised. The magnet locating system includes a wireless probe that sends a signal to a range indication device that indicates the range from the end of the probe to the magnet implanted in the human body. This indication of distance to the magnet is preferably accomplished by an audio signal or a visual display.
摘要翻译： 公开了一种用于将细长永久磁体放置在怀疑是癌症的人体内的组织体积中的系统。 然后由磁性定位系统检测磁体的位置，磁体定位系统由外科医生使用以找到并移除包括组织边缘的可疑组织体积，以确保任何和所有癌细胞已被切除。 磁体定位系统包括一个无线探针，它将一个信号发送到一个范围指示装置，该指示装置指示从探针末端到植入人体的磁体的范围。 对磁体的距离的这种指示优选地通过音频信号或视觉显示来完成。
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公开(公告)号：US06783522B2
公开(公告)日：2004-08-31
申请号：US10236186
申请日：2002-09-09
申请人： Robert E. Fischell
发明人： Robert E. Fischell
IPC分类号： A61M2516
CPC分类号： A61M25/0075
摘要： Disclosed is a check valve for placement near the distal end of a catheter. A continuously smooth outer surface for the catheter with check valve system assures that there is no propensity for a blood clot to form in cracks on the system's outer surface. The check valve is a formed from a low durometer, highly elastic, elastomer cylindrical tube that is shrunk into a cylindrical groove that would typically be located near the catheter's distal end. When pressurized fluid is injected through the catheter, the cylinder that is placed over one or more holes in the cylindrical groove in the catheter is forced to expand radially outward which allows the fluid to be injected into the blood vessel. When the pressure is removed, the elastomer tube retracts to its normal position which position tightly covers the holes thereby preventing any blood from entering the catheter.
摘要翻译： 公开了一种用于放置在导管远端附近的止回阀。 具有止回阀系统的导管的连续光滑的外表面确保在系统外表面的裂缝中不存在形成血块的倾向。 止回阀由低硬度，高弹性的弹性体圆柱形管形成，其收缩成通常位于导管远端附近的圆柱形凹槽中。 当通过导管注入加压流体时，放置在导管中的圆柱形凹槽中的一个或多个孔上的圆筒被迫径向向外扩张，这允许流体注入血管。 当去除压力时，弹性体管缩回其正常位置，该位置紧密地覆盖孔，从而防止任何血液进入导管。
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公开(公告)号：US6120533A
公开(公告)日：2000-09-19
申请号：US193672
申请日：1998-11-13
申请人： Robert E. Fischell
发明人： Robert E. Fischell
CPC分类号： A61F2/958 , A61F2210/0095
摘要： Disclosed is a stent delivery system consisting of a stent delivery catheter, a guide wire over which the stent delivery catheter is advanced and a balloon angioplasty catheter that is placed over the guide wire and within the stent delivery catheter. The stent delivery catheter is an elongated cylindrical tube with a radioisotope stent placed at a distal section of the tube. Just proximal and just distal to the stent there is a proximal radioactive marker band and a distal radioactive marker band each of which are fixedly attached to the delivery catheter. After the stent has been properly positioned at the site of a vascular blockage such as an arterial stenosis, a balloon angioplasty catheter can be advanced over the guide wire and inside the delivery catheter. The balloon at a distal section of the balloon angioplasty catheter is then inflated which expands the stent and both radioactive marker bands radially outward against the wall of the blood vessel. By the use of this device, the regions of the vessel wall that are just proximal and just distal to the edges of the stent are given a sufficient dose of radiation so that the cells in that region become incapable of producing growth factor. By this method, the edge effect that is frequently encountered with a radioisotope stent is avoided.
摘要翻译： 公开了一种支架输送系统，其包括支架输送导管，导线，支架输送导管在其上前进，以及球囊血管成形术导管，放置在引导线上方和支架输送导管内。 支架输送导管是一种细长的圆柱形管，放射性同位素支架放置在管的远端部分。 在支架的近侧和刚好的远侧处存在近端放射性标记带和远端放射性标记带，其每个固定地附接到递送导管。 在支架已被适当地定位在诸如动脉狭窄的血管阻塞部位之后，球囊血管成形术导管可以在导丝和输送导管内部前进。 球囊血管成形术导管的远侧部分的球囊然后膨胀，其将支架和两个放射性标记带径向向外扩张抵靠血管的壁。 通过使用该装置，容器壁的刚好在支架边缘的刚好的远端的区域被给予足够的辐射剂量，使得该区域中的细胞不能产生生长因子。 通过这种方法，避免了放射性同位素支架经常遇到的边缘效应。
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