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公开(公告)号：US11166691B2
公开(公告)日：2021-11-09
申请号：US14124822
申请日：2012-06-12
申请人： Roland Proksa , Ladislav Jankovic
发明人： Roland Proksa , Ladislav Jankovic
摘要： A system (200) includes a first imaging system (201) that utilizes first radiation to image an interior region of interest of a subject, including a first agent in the region of interest and a second imaging system (218) that utilizes second radiation to image a second agent in the region of interest, wherein an output of the second imaging system is used to trigger the first imaging system to scan the region of interest, including the first agent in the region of interest.
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公开(公告)号：US09597042B2
公开(公告)日：2017-03-21
申请号：US13266556
申请日：2010-04-09
申请人： Roland Proksa , Michael Grass
发明人： Roland Proksa , Michael Grass
摘要： A method is disclosed that includes decomposing, with a decomposer, agent-based time series projection data for an object or a subject into at least an agent based component. A projection data decomposer includes a time series decomposer that determines agent-based projection data based on agent-based time series projection data based on at least two energy dependent components. A computer readable storage medium containing instructions which, when executed by a computer, cause the computer to perform the act of determining an agent-based component of agent-based time series projection data utilizing at least two components of the agent-based time series projection is provided.
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公开(公告)号：US09316601B2
公开(公告)日：2016-04-19
申请号：US13981610
申请日：2012-01-25
申请人： Roland Proksa , Gerhard Martens
发明人： Roland Proksa , Gerhard Martens
CPC分类号： G01N23/04 , A61B6/032 , A61B6/06 , A61B6/4042 , A61B6/4241 , A61B6/5205 , A61B6/5258 , G01N23/046 , G01N2223/419 , G06T11/003
摘要： The invention relates to a detection values processing apparatus. Energy-dependent detection values are provided, which are indicative of polychromatic radiation (4) after having traversed an examination zone (5). The radiation is filtered by a filter (15) which comprises K-edge filter material. A component decomposition technique is applied to the detection values for determining K-edge attenuation values being first component attenuation values, which are indicative of an attenuation caused by the K-edge filter material, and additional component attenuation values, which are indicative of an attenuation caused by additional components of the examination zone, wherein an image of the examination zone is reconstructed from the additional component attenuation values. An image can therefore be reconstructed, which is not adversely affected by the filter, because the K-edge attenuation values are not used for reconstructing the image. This can improve the quality of the reconstructed image.
摘要翻译： 本发明涉及一种检测值处理装置。 提供依赖于能量的检测值，这些检测值指示经过检查区域（5）之后的多色辐射（4）。 辐射由包括K边缘过滤材料的过滤器（15）过滤。 分量分解技术被应用于用于确定作为表示由K边缘滤波器材料引起的衰减的第一分量衰减值的K边缘衰减值的检测值以及指示衰减的附加分量衰减值 由检查区域的附加组件引起，其中从附加分量衰减值重建检查区域的图像。 因此，由于K边缘衰减值不用于重建图像，因此可以重构图像，其不受滤波器的不利影响。 这可以提高重建图像的质量。
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公开(公告)号：US09159462B2
公开(公告)日：2015-10-13
申请号：US14000414
申请日：2012-02-20
申请人： Ewald Rossl , Thomas Koehler , Roland Proksa
发明人： Ewald Rossl , Thomas Koehler , Roland Proksa
CPC分类号： G21K1/00 , A61B6/027 , A61B6/032 , A61B6/4035 , A61B6/4078 , A61B6/4233 , A61B6/482
摘要： The invention relates to a detection apparatus comprising a filter (20) for filtering a conical radiation beam (4) such that at least a first region (22) and a second region (23) of the radiation beam are generated having different energy spectra, wherein the first region of the radiation beam illuminates a first detector area (25) on a detection surface (21) of a detector, thereby generating a first set of detection values, and the second region of the radiation beam illuminates a second detector area (26) on the detection surface, thereby generating a second set of detection values. For example, by using the filter the detection apparatus can be used as dual-energy computed tomography apparatus, wherein, for instance, a standard computed tomography apparatus can be transformed to a dual-energy computed tomography apparatus by adding the filter to the standard computed tomography apparatus, preferentially without modifying the radiation source and the detector.
摘要翻译： 本发明涉及一种检测装置，其包括用于过滤锥形辐射束（4）的过滤器（20），使得产生具有不同能谱的辐射束的至少第一区域（22）和第二区域（23） 其中辐射束的第一区域照射检测器的检测表面（21）上的第一检测器区域（25），从而产生第一组检测值，并且辐射束的第二区域照亮第二检测器区域 26），从而产生第二组检测值。 例如，通过使用滤波器，检测装置可以用作双能计算机断层摄影装置，其中，例如，标准计算机断层摄影装置可以通过将滤波器加到标准计算机断层摄影装置 优选不改变辐射源和检测器的断层摄影装置。
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公开(公告)号：US09055919B2
公开(公告)日：2015-06-16
申请号：US13000384
申请日：2009-06-22
申请人： Roland Proksa
发明人： Roland Proksa
CPC分类号： A61B6/504 , A61B5/4869 , A61B6/032 , A61B6/481 , A61B6/482 , A61B6/501 , A61B6/507 , A61K49/00 , A61M5/007
摘要： A method includes concurrently modulating administration of at least two different contrast agents to a subject during an imaging procedure based on a modulation profile. The at least two different contrast agents exhibit different spectral characteristics. The method further includes performing a spectral decomposition of data indicative of the at least two different contrast agents, determining concentrations of the at least two different contrast agents based on the spectral reconstruction, and determining a perfusion parameter based on a ratio of the concentrations and the modulation profile.
摘要翻译： 一种方法包括基于调制曲线在成像过程期间同时调节对受试者的至少两种不同造影剂的施用。 至少两种不同的造影剂表现出不同的光谱特征。 该方法还包括执行指示至少两种不同造影剂的数据的光谱分解，基于光谱重建来确定至少两种不同造影剂的浓度，以及基于浓度和浓度的比例确定灌注参数 调制曲线。
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公开(公告)号：US20130279785A1
公开(公告)日：2013-10-24
申请号：US13994775
申请日：2011-12-15
IPC分类号： G06T11/00
CPC分类号： G06T11/003 , G06T11/006 , G06T2211/408 , G06T2211/424
摘要： The noise of a detection value acquired by an imaging system (30) can depend on the contributions of different components within a region of interest to be imaged, which has been traversed by radiation (4) causing the respective acquired detection value. This dependence is considered while iteratively reconstructing an image of the region of interest, wherein first component attenuation values, which correspond to elements of a first component within the region of interest, and second component attenuation values, which correspond to elements of a first component within the region of interest, are determined, wherein noise values are determined from the first component attenuation values and the second component attenuation values and wherein the noise values are used for updating the image. This consideration of the dependence of the noise of an acquired detection value on the different components improves the quality of the iteratively reconstructed image.
摘要翻译： 由成像系统（30）获取的检测值的噪声可以取决于被成像的感兴趣区域内的不同部件的贡献，其已被辐射（4）穿过，导致相应的获取的检测值。 在迭代地重建感兴趣区域的图像的同时考虑这种依赖性，其中对应于感兴趣区域内的第一分量的元素的第一分量衰减值和与第一分量衰减值对应的第二分量衰减值 确定感兴趣区域，其中根据第一分量衰减值和第二分量衰减值确定噪声值，并且其中噪声值用于更新图像。 对所获取的检测值的噪声对不同分量的依赖性的考虑改善了迭代重建图像的质量。
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公开(公告)号：US20130182820A1
公开(公告)日：2013-07-18
申请号：US13825410
申请日：2011-09-28
申请人： Roland Proksa
发明人： Roland Proksa
CPC分类号： G21K1/10 , A61B6/032 , A61B6/4021 , A61B6/4035 , A61B6/5258 , G01N23/046 , G21K1/04
摘要： An imaging system including a source (310) having a focal spot (406) that emits a radiation beam that traverses an examination region, a radiation sensitive detector array (316) having a plurality of pixels that detects radiation traversing the examination region and generates projection data indicative of the detected radiation, and a filter (314), disposed between the source and the examination region, that filters peripheral regions of the emitted radiation, wherein the filter includes two separate and moveable regions (402), each region having a substantially same thickness and constant homogeneity.
摘要翻译： 一种成像系统，包括具有发射穿过检查区域的辐射束的焦点（406）的源（310），具有多个像素的辐射敏感检测器阵列（316），该多个像素检测穿过检查区域的辐射并产生投影 设置在源和检查区域之间的滤波器（314），其对所发射的辐射的周边区域进行滤波，其中滤波器包括两个分离的和可移动的区域（402），每个区域具有基本上 相同的厚度和恒定的均匀性。
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公开(公告)号：US08180017B2
公开(公告)日：2012-05-15
申请号：US12746364
申请日：2008-12-12
申请人： Peter Forthmann , Roland Proksa , Axel Thran
发明人： Peter Forthmann , Roland Proksa , Axel Thran
CPC分类号： H01J35/10 , A61B6/027 , A61B6/032 , A61B6/4007 , A61B6/4014 , A61B6/4021 , A61B6/4028 , A61B6/4035 , A61B6/4266 , G21K1/10 , H01J35/26 , H01J2235/068 , H01J2235/086
摘要： A computed tomography apparatus (10) includes spaced radiation sources (82, 84), such as anodes, which each propagate a cone-beam of radiation (40, 50) into an examination region (14). A detector (22) detects radiation which has passed through the examination region. An attenuation system (55) interposed between the radiation sources and the examination region for cone-angle dependent filtering of the cone beams. The attenuation system allows rays which contribute little to a reconstructed image to be attenuated more than rays which contribute more.
摘要翻译： 计算机断层摄影装置（10）包括间隔开的辐射源（82,84），例如阳极，其每个辐射源将辐射束（40,50）传播到检查区域（14）中。 检测器（22）检测已经通过检查区域的辐射。 介于辐射源与锥形束的锥角相关滤波检查区域之间的衰减系统（55）。 衰减系统允许对重建图像贡献很小的光线比有助于更多的光线衰减更多。
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公开(公告)号：US20110135052A1
公开(公告)日：2011-06-09
申请号：US13003320
申请日：2009-07-14
申请人： Roland Proksa
发明人： Roland Proksa
IPC分类号： G01N23/087 , G01N23/083
CPC分类号： A61B6/405 , A61B6/032 , A61B6/4014 , A61B6/4035 , A61B6/482 , G01T1/17
摘要： An imaging system includes at least one radiation generating component (210) that alternately emits different radiation that traverse an examination region and a common detector (214) that detects radiation that traverses the examination region and generates a signal indicative thereof. Pulse generating circuitry (304) generates a pulse train, including a plurality of pulses, with a frequency indicative of the signal for the at least one radiation generating component (210) for a sampling interval. Processing electronics (220) determine an approximation of the signal for one of the at least one radiation generating components (210) for the sampling interval based on a number of pulses in the pulse train for the sampling interval and charge of the pulses in the pulse train.
摘要翻译： 成像系统包括交替发射穿过检查区域的不同辐射的至少一个辐射产生部件（210）和检测穿过检查区域的辐射并产生指示其的信号的公共检测器（214）。 脉冲发生电路（304）产生包括多个脉冲的脉冲序列，其中频率指示用于至少一个辐射产生部件（210）的信号用于取样间隔。 处理电子设备（220）基于采样间隔的脉冲序列中的脉冲数量和脉冲中的脉冲的电荷来确定用于采样间隔的至少一个辐射产生部件（210）中的一个的信号的近似值 培养。
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120.发明申请公开(公告)号：US20110122998A1
公开(公告)日：2011-05-26
申请号：US13054504
申请日：2009-07-22
申请人： Roland Proksa
发明人： Roland Proksa
CPC分类号： G01T1/2928
摘要： The present application relates to a combined anti-scatter grid, cathode, and carrier for a photon detector used in spectral CT imaging. The photon detector of the present application may include a cathode having at least one outwardly extending plate and at least one base plate, a substrate having at least one anode, and a converter material, such as for example, Cadmium Zinc Telluride (“CZT”) or Cadmium Telluride. The at least one outwardly extending plate of the cathode may extend above the other detector components to act as an anti-scatter grid for the detector. Further, the at least one outwardly extending plate of the cathode may extend below the other detector components and be fixed to the at least one base plate of the detector. The converter material may be attached to at least one side of the at least one outwardly extending plate of the cathode.
摘要翻译： 本申请涉及用于光谱CT成像中的用于光子检测器的组合防散射网格，阴极和载体。 本申请的光子检测器可以包括具有至少一个向外延伸的板和至少一个基板，具有至少一个阳极的基板和转换器材料的阴极，例如碲化锌镉镉（“CZT” ）或碲化镉。 阴极的至少一个向外延伸的板可以在其它检测器部件上方延伸，以用作检测器的防散射栅格。 此外，阴极的至少一个向外延伸的板可以延伸到其他检测器部件的下方并且被固定到检测器的至少一个基板。 转换器材料可以附接到阴极的至少一个向外延伸板的至少一侧。
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