Tissue sealants from plasma derived proteins
    123.
    发明授权
    Tissue sealants from plasma derived proteins 有权
    血浆衍生蛋白的组织密封剂

    公开(公告)号:US08846849B2

    公开(公告)日:2014-09-30

    申请号:US13107375

    申请日:2011-05-13

    IPC分类号: C08G63/668

    CPC分类号: A61L24/106

    摘要: The present invention is directed in one embodiment to a tissue adhesive or sealant composition comprising an electrophilic group containing cross-linking compound having a linker moiety of a diglycolic acid, a water soluble core moiety and an electrophilic group that is covalently bonded to the diglycolic acid linker moiety and a nucleophilic group containing protein. In other embodiments, the present invention is directed to a delivery device or a medical device on which the composition has been applied or incorporated therein. The present invention is also directed to a method for sealing tissue using the tissue adhesive or sealant composition.

    摘要翻译: 本发明在一个实施方案中涉及一种组织粘合剂或密封剂组合物,其包含亲电子基团,该亲电子基团含有交联化合物,该交联化合物具有二甘醇酸的接头部分,水溶性核心部分和与二甘醇酸共价结合的亲电子基团 接头部分和含亲核基团的蛋白质。 在其它实施方案中,本发明涉及其上已经施用或并入其中的组合物的递送装置或医疗装置。 本发明还涉及使用组织粘合剂或密封剂组合物密封组织的方法。

    LAPROSCOPIC INSTRUMENT DEPTH STOP
    124.
    发明申请
    LAPROSCOPIC INSTRUMENT DEPTH STOP 审中-公开
    LAPROSCOPIC仪器深度停止

    公开(公告)号:US20140276907A1

    公开(公告)日:2014-09-18

    申请号:US13798664

    申请日:2013-03-13

    IPC分类号: A61B17/32

    摘要: Disclosed is an infinitely adjustable depth stop for a laparoscopic instrument having a shaft, the depth stop including a first component having a first annular space adapted to allow the shaft to be fitted therethrough. The first annular space has a reducible diameter and an interference surface against which the shaft may be fitted. Upon reduction of the reducible diameter, the interference surface frictionally engages the shaft to arrest relative movement of the depth stop along the shaft. The frictional engagement may be along a curve, a spiral curve, or an area. Means are also provided to reopen the reducible diameter to release the depth stop.

    摘要翻译: 公开了一种用于具有轴的腹腔镜器械的无限可调深度限位器,深度限位器包括具有适于允许轴穿过其中的第一环形空间的第一部件。 第一环形空间具有可还原的直径和干涉表面,轴可与该干涉面相配合。 一旦降低了可还原直径,干涉表面摩擦地接合轴,以阻止深度挡块沿着轴的相对运动。 摩擦接合可以沿着曲线,螺旋曲线或区域。 还提供了重新打开可还原直径以释放深度停止的装置。

    Collapsible barbed sutures having reduced drag and methods therefor
    126.
    发明授权
    Collapsible barbed sutures having reduced drag and methods therefor 有权
    可折叠的有倒钩的缝合线具有减少的阻力和方法

    公开(公告)号:US08821539B2

    公开(公告)日:2014-09-02

    申请号:US12177947

    申请日:2008-07-23

    IPC分类号: A61B17/04 A61B17/06 A61B17/00

    摘要: A barbed suture includes a flexible thread having a core with a leading end, a trailing end, and a central axis. The barbed suture includes a first flexible flap connected to the core, the first flap extending between the leading and trailing ends of the core, and a second flexible flap connected to the core, the second flap extending between the leading and trailing ends of the core. The flexible flaps and the core have an S-shaped profile when viewed in cross-section. The barbed suture includes first and second slots formed in the respective first and second flaps for dividing the flaps into first and second barbs projecting from the core, whereby each slot extends outwardly from the core and rearwardly toward the trailing end of the core.

    摘要翻译: 有倒钩的缝合线包括具有带有前端,后端和中心轴的芯的柔性线。 有倒勾的缝合线包括连接到芯的第一柔性瓣,第一翼在芯的前端和后端之间延伸,以及连接到芯的第二柔性瓣,第二瓣在芯的前端和后端之间延伸 。 当横截面看时,柔性翼片和芯体具有S形轮廓。 有倒钩的缝合线包括形成在相应的第一和第二翼片中的第一和第二槽,用于将翼片分成从芯部突出的第一和第二倒钩,由此每个槽从芯部向外延伸并向后延伸到芯的后端。

    Magnetic implants and methods for treating an oropharyngeal condition
    127.
    发明授权
    Magnetic implants and methods for treating an oropharyngeal condition 有权
    磁性植入物和治疗口咽病症的方法

    公开(公告)号:US08813754B2

    公开(公告)日:2014-08-26

    申请号:US13735766

    申请日:2013-01-07

    IPC分类号: A61F5/56 A61B19/00

    摘要: Magnetic devices and implantation methods are provided for use in the treatment of obstructive sleep apnea. The devices include a sheet-like element having ferromagnetic qualities. The device may also include a permanent magnet attached to the sheet-like element by magnetic forces. The devices are implanted in soft tissue surrounding the airway and in tissue space beneath the pharyngeal wall to exert forces on and/or change the shape of the soft tissue. The magnetic devices may also include a bladder containing a magnetorheological fluid that stiffens soft tissue when exposed to a magnetic field.

    摘要翻译: 提供磁性装置和植入方法用于治疗阻塞性睡眠呼吸暂停。 这些装置包括具有铁磁性质的片状元件。 该装置还可以包括通过磁力附着到片状元件的永磁体。 将装置植入围绕气道的软组织和咽壁下方的组织空间中以施加力和/或改变软组织的形状。 磁性装置还可以包括含有磁流变流体的囊状物,当暴露于磁场时,该液体硬化软组织。

    Sealant Delivery Device for Anastomotic Stapler
    129.
    发明申请
    Sealant Delivery Device for Anastomotic Stapler 有权
    用于吻合缝合器的密封剂输送装置

    公开(公告)号:US20140207186A1

    公开(公告)日:2014-07-24

    申请号:US13745948

    申请日:2013-01-21

    申请人: ETHICON, INC.

    IPC分类号: A61B17/00 A61B17/115

    摘要: The present invention relates to surgical instruments and a method for applying an adhesive or sealant to an anastomosis site immediately prior and/or during anastomotic surgical stapling. The present invention further relates to surgical instruments, devices, and methods for applying sealant to a target tissue of a surgical site being anastomotically joined so as to prevent leakage.

    摘要翻译: 本发明涉及手术器械以及在吻合口吻合期间和/或之间立即将粘合剂或密封剂施用于吻合部位的方法。 本发明还涉及用于将缝合剂施加到手术部位的目标组织的外科器械,装置和方法,所述外科手术部位被吻合以防止渗漏。