公开(公告)号：US20210170423A1

公开(公告)日：2021-06-10

申请号：US16763790

申请日：2018-11-14

Applicant: University of Florida Research Foundation, Inc.

Inventor： Jon P. DOBSON ,  Isaac Ernest Philip FINGER-BAKER

IPC: B03C1/00 ,  B03C1/01 ,  B03C1/033 ,  B03C1/28

Abstract: Embodiments of the present disclosure include separating devices and systems and methods of use. Embodiments of the present disclosure include separation devices including magnetic arrays and sheet-flow separation chambers. In an embodiment, the separating device enables the generation of multiple, and in some configurations, intersecting, high gradient magnetic field lines, resulting in strong separation forces, which permit for scale up to large areas and/or volumes (e.g., extracorporeal blood filtration system).

公开(公告)号：US11030737B2

公开(公告)日：2021-06-08

申请号：US16573922

申请日：2019-09-17

Applicant: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.

Inventor： Mark M. Tehranipoor ,  Haoting Shen ,  Nidish Vashistha ,  Navid Asadizanjani ,  Mir Tanjidur Rahman ,  Damon Woodard

IPC: G06T7/00 ,  G06T5/40 ,  G06K9/62 ,  G06T7/136

Abstract: A method of detecting hardware Trojans in an IC includes providing a golden IC layout data set or SEM image data taken at long dwelling time on an active area of the golden IC after polishing it from the backside. Next, the IC under authentication (IUA) sample is prepared for fast SEM imagining (shorter dwelling time) after backside thinning. Next step is to perform image processing on the IUA's SEM image, which includes histogram equalization with noise filtering using Gaussian and Median filters. In the last step, the IUA sample data with the shorter dwelling time is compared with the golden IC layout data or the golden image data from high quality (longer dwelling time) SEM scanning process. At the end the result of the comparison is used to identify hardware Trojans.

公开(公告)号：US20210163451A1

公开(公告)日：2021-06-03

申请号：US17049708

申请日：2019-05-16

Applicant: University of Florida Research Foundation, Inc.

Inventor： Yousong Ding ,  Guangde Jiang

IPC: C07D403/06 ,  A01N43/60

Abstract: Thaxtomins are phytotoxic secondary metabolites produced in plant pathogenic Streptomyces strains and have received considerable interests as bioherbicides. A cell-free, biocombinatorial approach was developed to produce a thaxtomin library for herbicide development. Combination of biosynthetic enzymes led to the production of 136 substituted 2,5-diketopiperazines, thaxtomin D, thaxtomin B and thaxtomin A analogs in a single pot. Furthermore, rational engineering of TxtA allowed the synthesis of azido-containing thaxtomin analog. Selected unnatural thaxtomins demonstrated improved herbicidal activities. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.

公开(公告)号：US20210155952A1

公开(公告)日：2021-05-27

申请号：US16761409

申请日：2018-11-05

Applicant: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.

Inventor： Nian WANG

IPC: C12N15/82

Abstract: The disclosure relates to a plant that is tolerant or resistant to species of Ca. Liberibacter. Specifically exemplified are citrus and solanaceous plants. Provided by the disclosure is a modified citrus or solanaceous plant that is resistant or tolerant to Sec-dependent effectors secreted by bacteria. Also provided by the disclosure are methods of modifying a plant genome plant to provide tolerance or resistance to species of Ca. Liberibacter. Still further provided by the disclosure are methods conferring a population of plants with tolerance or resistance to species of Ca. Liberibacter and screening that population for the plants that are tolerant or resistant to species of Ca. Liberibacter.

公开(公告)号：US10978908B2

公开(公告)日：2021-04-13

申请号：US16077239

申请日：2017-02-10

Applicant: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. ,  MEDIATEK SINGAPORE PTE. LTD.

Inventor： Patrick Riehl ,  Jenshan Lin ,  Ron-Chi Kuo

IPC: H02J50/10 ,  H02J50/50 ,  H02J7/00 ,  H02J50/00 ,  H02J50/40 ,  H02J7/02

Abstract: Various examples are provided for wireless power charging for versatile receiver positions. In one example, a three dimensional array of transmitter coils is positioned around a charging area. A control circuit causes the array of transmitter coils to generate a magnetic field that charges a device with any position and orientation in the charging area.

公开(公告)号：US10971292B2

公开(公告)日：2021-04-06

申请号：US16466409

申请日：2017-12-07

Applicant: University of Florida Research Foundation, Inc.

Inventor： David P. Arnold ,  Camilo Velez Cuervo

IPC: H01F7/02 ,  H01F7/20 ,  H01F13/00

Abstract: Embodiments of the subject invention relate to an electropermanent magnet core (EPM core) having two permanent magnets (or two permanent magnet portions where each portion can have one or more permanent magnets), including a fixed permanent magnet portion and a switching permanent magnet portion, where a switching magnetic field is used to switch the magnetization of the switching permanent magnet portion, but not switch the magnetization of the fixed permanent magnet portion. In this way, the fixed permanent magnet portion has a fixed magnetization, such that the direction of magnetization of the fixed permanent magnet portion remains the same during switching of the magnetization of the switching permanent magnet portion, given the magnitude and duration of the switching magnetic field used to switch the magnetization of the switching permanent magnet portion, and the switching permanent magnet portion has a switching magnetization, such that the direction of magnetization of the switching permanent magnet portion is switched during switching of the magnetization of the switching permanent magnet portion, given the magnitude and duration of the switching magnetic field used to switch the magnetization of the switching permanent magnet portion.

公开(公告)号：US20210093704A1

公开(公告)日：2021-04-01

申请号：US16963761

申请日：2019-01-23

Applicant: University of Florida Research Foundation, Inc.

Inventor： Roy CURTISS, III ,  Banikalyan SWAIN

IPC: A61K39/02 ,  A61K39/395 ,  C12N1/20

Abstract: Disclosed herein are nucleic acids, vector systems, and vaccines for vaccinating fresh water and marine fish using Ichthyophthirius multifiliis (Ich) i-antigens. In particular, a recombinant attenuated Edwardsiella vaccine (RAEV) vector system is disclosed with regulated delayed attenuation and regulated delayed lysis in vivo attributes that synthesizes Ich protective antigens to enable vaccination of fresh water and marine fish species susceptible to white spot disease. This vaccine construct is designed to exhibit the invasive properties of virulent Edwardsiella at the time of bath immunization and then is programmed to gradually lose virulence attributes and to synthesize protective antigens as a consequence of in vivo cell division as the RAEV colonizes internal effector lymphoid tissues. The ultimate lysis in vivo delivers a bolus of protective antigen along with immunostimulatory molecules to exhibit complete biological containment with no potential for survival in vivo or ex vivo.

公开(公告)号：US20210070847A1

公开(公告)日：2021-03-11

申请号：US16958823

申请日：2018-12-28

Applicant: University of Florida Research Foundation, Inc.

Inventor： Benoit Giasson ,  Todd Eliot Golde ,  Cara Louise Croft ,  Yona Levites ,  Brenda Dawn Moore

IPC: C07K16/18 ,  G01N33/533 ,  G01N33/535 ,  A61B5/00

Abstract: Disclosed herein are monoclonal antibodies targeting specific tau epitopes, particularly, microtubule binding domain region 2 or region 4. Also disclosed herein are antibodies or antigen binding fragments thereof that specifically recognize a tau epitope consisting of the amino acid sequence of SEQ ID NO: 9 or 11. Also disclosed herein are methods of detecting tau protein in a subject, comprising performing an assay using the antibodies or antigen binding fragments thereof on the subject or on a biological sample obtained from the subject. Assay kits containing the disclosed antibodies are also provided. Further, methods of treating or preventing a tauopathy in a subject by administering to the subject tau antibodies or antigen-binding fragments thereof are provided.

公开(公告)号：US20210060531A1

公开(公告)日：2021-03-04

申请号：US16321494

申请日：2017-07-31

Applicant: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.

Inventor： BRIJ M. MOUDGIL ,  VIJAY KRISHNA ,  BENJAMIN L. KOOPMAN ,  WEI BAI

IPC: B01J21/06 ,  B01J21/18 ,  B01J35/00 ,  B01J35/02 ,  B01J37/02 ,  A61L2/232 ,  A01N59/16 ,  A01N25/00

Abstract: A visible light photocatalyst coating includes a metal oxide that in the presence of a organic contaminate that absorbs at least some visible light or includes the metal oxide and an auxiliary visible light absorbent, where upon absorption of degradation of the organic contaminate occurs. Contaminates can be microbes, such as bacteria, viruses, or fungi. The metal oxide is nanoparticulate or microparticulate. The metal oxide can be TiO2. The coating can include an auxiliary dye having an absorbance of light in at least a portion of the visible spectrum. The coating can include a suspending agent, such as NaOH. The visible light photocatalyst coating can cover a surface of a device that is commonly handled or touched, such as a door knob, rail, or counter.

公开(公告)号：US20210059842A1

公开(公告)日：2021-03-04

申请号：US16643372

申请日：2018-08-31

Applicant: Brian P. Bartlett ,  University of Florida Research Foundation, Inc.

Inventor： Wallace Gregory Sawyer ,  Brian P. Bartlett ,  Derek L. Hood

IPC: A61F2/78 ,  A61F2/60 ,  A61F2/76 ,  A61F2/54

Abstract: Various examples are provided for modular prosthetic devices and their use. In one example, a device includes a chassis assembly including a joint portion; and an interchangeable module that can be removably attached to the chassis assembly. The interchangeable modules can be configured for use in a wide variety of applications. The interchangeable modules can be quickly exchanged for different activities.