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    Method for Producing Polymer-Encapsulated Nanoparticles
    123.
    发明申请
    Method for Producing Polymer-Encapsulated Nanoparticles 审中-公开
    生产聚合物包封纳米颗粒的方法

    公开(公告)号：US20130022742A1

    公开(公告)日：2013-01-24

    申请号：US13548366

    申请日：2012-07-13

    Applicant: Robiah Yunus ,  Mahshid Kalani

    Inventor： Robiah Yunus ,  Mahshid Kalani

    IPC: B05D7/00

    CPC classification number: B01J13/043 ,  A61K9/5153 ,  A61K9/5192

    Abstract: The present invention relates to a method for producing polymer-encapsulated nanoparticles comprising the steps of: pumping supercritical fluid into a pressurised vessel, at a predetermined pressure; spraying a solution comprising a compound to be encapsulated, a polymer and an organic solvent into the vessel; collecting precipitated particles on a filter; and washing the particles with the supercritical fluid to remove residual solvent; characterised in that: the difference between the melting point of the polymer and the melting point of the compound to be encapsulated is not more than 10° C.

    Abstract translation: 本发明涉及一种生产聚合物包封的纳米颗粒的方法，包括以下步骤：在预定压力下将超临界流体泵入加压容器; 将包含要包封的化合物，聚合物和有机溶剂的溶液喷射到容器中; 将沉淀的颗粒收集在过滤器上; 并用超临界流体洗涤颗粒以除去残余溶剂; 其特征在于：聚合物的熔点与待包封的化合物的熔点之间的差不超过10℃

    Microcapsule Corrosion Control In Reinforced Concrete
    124.
    发明申请
    Microcapsule Corrosion Control In Reinforced Concrete 有权
    微胶囊腐蚀控制在钢筋混凝土中的应用

    公开(公告)号：US20120252934A1

    公开(公告)日：2012-10-04

    申请号：US13139583

    申请日：2011-03-29

    Applicant: Seth Miller ,  Thomas A. Yager

    Inventor： Seth Miller ,  Thomas A. Yager

    IPC: C04B16/04 ,  B32B5/16

    CPC classification number: C04B40/0633 ,  B01J13/043 ,  C04B20/1033 ,  C04B28/02 ,  C04B2103/0094 ,  C04B2111/00112 ,  C04B2111/26 ,  Y10T428/2998 ,  C04B22/062 ,  C04B22/10 ,  C04B22/16 ,  C04B32/02

    Abstract: Corrosion control in reinforced concrete is generally disclosed. Some example embodiments may include concrete including aggregate, cement, and/or microcapsules distributed within the cement, where the individual microcapsules may include a high pH salt substantially contained within an acid-soluble shell. If the pH of the concrete decreases, the acid soluble shell may swell and/or dissolve, such as below a pH of about 11, which may release the high pH salt. The high pH salt may locally increase the pH of the concrete. By increasing the pH above about pH 11, corrosion of steel rebar may be prevented and/or reduced.

    Abstract translation: 通常公开了钢筋混凝土中的腐蚀控制。 一些示例性实施方案可以包括混合物，其包括分布在水泥内的聚集体，水泥和/或微胶囊，其中各个微胶囊可以包含基本上包含在酸溶性壳内的高pH盐。 如果混凝土的pH值降低，则酸溶性壳可能溶胀和/或溶解，例如低于约11的pH，这可释放高pH盐。 高pH值的盐可以局部增加混凝土的pH值。 通过将pH提高到约pH 11以上，可以防止和/或减少钢筋的腐蚀。

    METHOD OF PREPARING NANO-DISPERSED HIGH-ALL-TRANS-CAROTENOID MICROCAPSULES
    126.
    发明申请
    METHOD OF PREPARING NANO-DISPERSED HIGH-ALL-TRANS-CAROTENOID MICROCAPSULES 有权
    制备纳米分散高转移CAROTENOID微球的方法

    公开(公告)号：US20120018912A1

    公开(公告)日：2012-01-26

    申请号：US13259291

    申请日：2010-03-18

    Applicant: Zhirong Chen ,  Jianfeng Chen ,  Hong Yin ,  Hong Zhao ,  Dan Qiu ,  Lifang Shi ,  Jiandong Li ,  Guangwen Chu ,  Lei Shao

    Inventor： Zhirong Chen ,  Jianfeng Chen ,  Hong Yin ,  Hong Zhao ,  Dan Qiu ,  Lifang Shi ,  Jiandong Li ,  Guangwen Chu ,  Lei Shao

    IPC: B29B9/12

    CPC classification number: B01J13/043 ,  A23K20/179 ,  A23L5/44 ,  A23L33/10 ,  A23L33/105 ,  A23P10/30 ,  A23V2002/00 ,  A61K8/0241 ,  A61K8/11 ,  A61K8/31 ,  A61K8/35 ,  A61K31/01 ,  A61K31/122 ,  A61K2800/412 ,  A61Q19/00 ,  C09B61/00 ,  C09B67/0097 ,  A23V2250/211 ,  A23V2200/224

    Abstract: A method of preparing nano-dispersed high-all-trans-carotenoid microcapsules is provided, comprising: preparing 10-20% carotenoid suspension by milling the high-all trans-carotenoid crystals with dichloromethane until the particle size thereof is in the range of 2-5 μm, then supplying the suspension together with preheated dichloromethane of another pass into a dissolving tank to obtain a solution of 0.5-2%; delivering the solution together with ethanol or isopropanol into a crystallization device having high gravity rotating packed bed simultaneously and continuously, and then into a wiped-film evaporator for desolvation until the solid content is 10-20%, then a transparent alcohol dispersion of carotenoid is obtained; mashing the alcohol dispersion together with an aqueous solution containing an antioxidant and protective colloid and spray drying to obtain nano-dispersed high-all-trans-carotenoid microcapsules. As the crystals are nano-dispersed and the content of trans-isomer is more than 90%, the carotenoid microcapsules of present inventions exhibit high bioavailability.

    Abstract translation: 提供了一种制备纳米分散高全反式类胡萝卜素微胶囊的方法，包括：通过用二氯甲烷研磨高全反式类胡萝卜素晶体制备10-20％的类胡萝卜素悬浮液，直到其粒径在2 -5μm，然后将悬浮液与另一道次的预热二氯甲烷一起供入溶解槽中，得到0.5-2％的溶液; 将溶液与乙醇或异丙醇一起输送到具有高重力旋转填充床的结晶装置中，同时且连续地进行，然后进入擦膜蒸发器进行去溶剂化直到固体含量为10-20％，然后将类胡萝卜素的透明醇分散体 获得; 将醇分散体与含有抗氧化剂和保护胶体的水溶液一起糖化并喷雾干燥，得到纳米分散的高全反式类胡萝卜素微胶囊。 由于晶体是纳米分散的并且反式异构体的含量大于90％，本发明的类胡萝卜素微胶囊显示出高的生物利用度。

    Multi-functional microcapsules and method and device for manufacturing same
    130.
    发明申请
    Multi-functional microcapsules and method and device for manufacturing same 审中-公开
    多功能微胶囊及其制造方法及装置

    公开(公告)号：US20070122488A1

    公开(公告)日：2007-05-31

    申请号：US11510869

    申请日：2006-08-24

    Applicant: Erich Windhab ,  Michael Zimmermann

    Inventor： Erich Windhab ,  Michael Zimmermann

    IPC: A61K9/50 ,  B29C39/10

    CPC classification number: A61K9/5073 ,  A61K9/5084 ,  A61K9/5089 ,  B01J13/043 ,  B01J13/046

    Abstract: Multimicrocapsules that include encapsulated components of at least one nutritionally, pharmacologically, or medically active functional substance, wherein, within an encapsulation of one or more layers of a first encapsulating material around a common capsule matrix, there are provided a first active functional component in an amount sufficient to provide functional benefits after being ingested by a subject and a component preserving or function enhancing substance present in an amount to preserve and enhance the functional benefits of the active functional component. The encapsulation delays release of the active functional component when the microcapsules are ingested by the subject and provides a synchronous or tuned release of the active functional component and component preserving or function enhancing substance in the intestine of the subject. Also, a process and apparatus for forming such microcapsules.

    Abstract translation: 包括至少一种营养，药理学或医学活性的功能性物质的包封组分的多微囊，其中在一个或多个第一包封材料层围绕公共胶囊基质的包封内，提供了第一活性功能组分 足以在被受试者摄取后提供功能益处的量，以及以保持和增强活性功能组分的功能益处的量存在的成分保存或功能增强物质。 当微胶囊被受试者摄取时，包封延缓了活性功能组分的释放，并且提供了在受试者的肠中活性功能组分和组分保存或功能增强物质的同步或调节释放。 另外，用于形成这种微胶囊的方法和装置。

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