公开(公告)号：US20240287416A1

公开(公告)日：2024-08-29

申请号：US18572194

申请日：2022-06-28

申请人： Conopco Inc., d/b/a UNILEVER

发明人： Paul Ferguson

IPC分类号： C11D3/37 ,  B01J13/12 ,  B01J13/22 ,  C11D3/22 ,  C11D17/00

CPC分类号： C11D3/3715 ,  B01J13/125 ,  B01J13/22 ,  C11D3/222 ,  C11D17/0039

摘要： A Provided herein is a benefit agent delivery particle having a core-shell structure in which a shell of polymeric material entraps a core containing benefit agent, and the shell includes a recycled polymer.

公开(公告)号：US20230143503A1

公开(公告)日：2023-05-11

申请号：US17964060

申请日：2022-10-12

申请人： The Hong Kong University of Science and Technology

发明人： Jinglei YANG ,  Dan LI ,  Ying ZHAO

IPC分类号： A62D1/00 ,  B01J13/12 ,  C08K9/10 ,  C09D5/18 ,  C09D7/40 ,  H01M10/42

CPC分类号： A62D1/0021 ,  B01J13/125 ,  C08K9/10 ,  C09D5/18 ,  C09D7/70 ,  H01M10/4235 ,  H01M2200/10

摘要： A method of preparing a fire extinguishing core-shell microcapsule by a one-pot oil-in-oil/ water emulsion technique. The method includes dissolving a fluid fluoroketone or hydrofluorocarbon fire extinguishing core material and a polymer shell material into a volatile solvent to form a composite mixture. The composite solution is emulsified into a polar phase and a non-polar phase by adjusting a concentration of a surfactant or via mechanical agitation to provide interfacial tension tuning. The volatile solvent is evaporated to precipitate a microcapsule having a fire extinguishing material core and a polymer shell. In a further aspect, the method includes incorporating the core-shell microcapsules in a polymer matrix.

公开(公告)号：US20180222806A1

公开(公告)日：2018-08-09

申请号：US15892269

申请日：2018-02-08

申请人： Hip Hing Construction Technology Limited

发明人： Hong Gang Zhu ,  Yuet Kee Lam ,  Xiao Hu Zhu ,  Man Lung Sham ,  Tomi Pekka Bernhard Nissinen ,  Jing Wen Liang ,  Su Ping Bao ,  Kwok Leung So

IPC分类号： C04B40/02 ,  C04B22/00 ,  C04B24/26 ,  B01J13/12 ,  B01J13/04 ,  C04B24/38

CPC分类号： C04B40/0295 ,  B01J13/043 ,  B01J13/046 ,  B01J13/125 ,  C04B20/1033 ,  C04B20/1055 ,  C04B22/002 ,  C04B24/2641 ,  C04B24/38 ,  C04B28/02 ,  C04B38/009 ,  C04B2103/005 ,  C04B2103/42 ,  C04B2111/40

摘要： The present application provides for water capsules, preparation methods of water capsules, a preparation method for lightweight concrete and a structure of lightweight concrete. Each of the water capsules comprises an alkali-sensitive shell and water inside; the water capsules are used to mix with a cementitious matrix, the water capsules can survive during concrete mixing and transportation processes but then gradually rupture in hardened concrete; the water released during the hardening of the concrete is beneficial for the hydration of the concrete. The water capsules and their preparation method, the preparation method for and structure of the lightweight concrete of the present application are of unique design and strong practicability.

公开(公告)号：US20160051954A1

公开(公告)日：2016-02-25

申请号：US14829578

申请日：2015-08-18

申请人： New York University

发明人： Jasna Brujic ,  Martin Haase

IPC分类号： B01J13/00 ,  B01J13/06

CPC分类号： B01J13/00 ,  A61K8/11 ,  A61K8/14 ,  A61K9/113 ,  A61K2800/10 ,  A61K2800/80 ,  A61K2800/805 ,  A61Q19/00 ,  B01F3/0807 ,  B01F5/045 ,  B01F13/0059 ,  B01J13/02 ,  B01J13/06 ,  B01J13/125

摘要： Multiple emulsions with an “onion” topology are useful vehicles for drug delivery, biochemical assays, and templating materials. They can be assembled by ternary liquid phase separation using microfluidics, but the control over their design is limited because the mechanism of their creation is unknown. Here it is shown that phase separation occurs via self-similar cycles of mass transfer, spinodal decomposition or nucleation, and coalescence into multiple layers. Mapping out the phase diagram demonstrates a linear relation between concentric layer diameters, whose slope depends on the initial ternary composition and the molecular weight of the surfactant. These general rules quantitatively predict the number of droplet layers (multiplicity). Further, self-assembly routes for polymer capsules and liposomes are provided with techniques to assemble lipid-stabilized droplets with ordered internal structures.

摘要翻译： 具有“洋葱”拓扑结构的多重乳液是用于药物递送，生化测定和模板材料的有用载体。 它们可以通过使用微流体的三元液相分离进行组装，但是对其设计的控制是有限的，因为它们的创建机制是未知的。 这表明通过质量传递，旋节分解或成核的自相似循环以及聚结成多层而发生相分离。 相图显示了同心层直径之间的线性关系，其斜率取决于初始三元组成和表面活性剂的分子量。 这些一般规则定量地预测了液滴层的数量（多重性）。 此外，聚合物胶囊和脂质体的自组装路线提供了用有序内部结构组装脂质稳定的液滴的技术。

公开(公告)号：US20150321159A1

公开(公告)日：2015-11-12

申请号：US14410706

申请日：2013-08-08

申请人： SEKISUI CHEMICAL CO., LTD.

发明人： Tadashi IWAMOTO ,  Hiroshi YAMAUCHI

IPC分类号： B01J13/12

CPC分类号： B01J13/12 ,  A23L27/72 ,  A23P10/30 ,  A61K8/11 ,  A61K8/65 ,  A61K8/8129 ,  A61K8/8147 ,  A61K8/8176 ,  A61K9/5026 ,  A61K9/5057 ,  A61K9/5089 ,  A61K2800/10 ,  A61K2800/412 ,  A61Q19/00 ,  B01J13/125 ,  Y10T428/2998

摘要： The present invention aims to provide a method for producing microcapsules, wherein the method can control the particle size and produce microcapsules excellent in retentivity and releasability of a water-soluble core agent. The present invention also aims to provide a microcapsule excellent in retentivity and releasability of a water-soluble core agent. The present invention provides a method for producing microcapsules comprising the steps of: preparing an emulsion by dispersing an aqueous solution A obtained by dissolving at least an aqueous solvent-soluble polymer and a water-soluble core agent in an aqueous solvent in a non-polar solution B obtained by dissolving an emulsifier or a dispersant in a non-polar medium; and forming a core-shell structure in which the water-soluble core agent is covered with a shell containing the aqueous solvent-soluble polymer by heating the emulsion at a temperature of 20° C. to 100° C. and/or decompressing the emulsion at a pressure of 0.1 to 0.001 MPa to remove the aqueous solvent, the weight ratio of the aqueous solution A to the non-polar solution B being 1/10 to 1/1.

摘要翻译： 本发明的目的在于提供一种生产微胶囊的方法，其中该方法可以控制粒度并产生水溶性核心试剂的保持性和脱模性优异的微胶囊。 本发明还旨在提供一种水溶性核心试剂的保持性和脱模性优异的微胶囊。 本发明提供一种生产微胶囊的方法，包括以下步骤：通过将至少将水性溶剂可溶性聚合物和水溶性芯剂溶解在水性溶剂中而得到的水溶液A分散在非极性 通过将乳化剂或分散剂溶解在非极性介质中获得的溶液B; 并且通过在20℃至100℃的温度下加热乳液和/或使乳液减压而形成其中水溶性核心试剂被含有水溶性可溶性聚合物的壳覆盖的核 - 壳结构。 在0.1〜0.001MPa的压力下除去水性溶剂，水溶液A与非极性溶液B的重量比为1/10〜1/1。

公开(公告)号：US20110224127A1

公开(公告)日：2011-09-15

申请号：US12722873

申请日：2010-03-12

申请人： Kevin Graham Blyth ,  Fabrizio Meli

发明人： Kevin Graham Blyth ,  Fabrizio Meli

IPC分类号： B01J13/02 ,  A61K8/11 ,  C11D3/50

CPC分类号： C11D3/505 ,  B01J13/125

摘要： A process for preparing an encapsulate, the process having the steps of: (i) emulsifying a hydrophobic perfume-polymer complex in water to form an oil in water emulsion; (ii) at least partially dissolving an encapsulating material in water; (iii) removing at least some water from the oil in water emulsion comprising the hydrophobic perfume-polymer complex and the encapsulating material to form an encapsulate.

摘要翻译： 一种制备包封物的方法，该方法具有以下步骤：（i）在水中乳化疏水性香料 - 聚合物复合物以形成水包油乳液; （ii）至少部分地将包封材料溶解在水中; （iii）从包含疏水性香料 - 聚合物复合物和包封材料的水包油乳液中除去至少一些水以形成包封物。

公开(公告)号：US20030224059A1

公开(公告)日：2003-12-04

申请号：US10400100

申请日：2003-03-25

发明人： E. Itzhak Lerner ,  Vered Rosenberger ,  Moshe Flashner-Barak ,  Anna Drabkin ,  Naomi Moldavski

IPC分类号： A61K031/7048 ,  A61K031/56 ,  A61K031/55 ,  A61K031/5513 ,  A61K031/4745 ,  A61K031/337

CPC分类号： A61K9/1682 ,  A61K9/167 ,  A61K9/1676 ,  A61K9/1694 ,  A61K31/519 ,  B01J13/02 ,  B01J13/125

摘要： Provided are microparticles of active pharmaceutical ingredients, drug delivery vehicles comprising same, and methods for making them.

摘要翻译： 提供了活性药物成分的微粒，包含其的药物递送载体及其制备方法。

公开(公告)号：US5744152A

公开(公告)日：1998-04-28

申请号：US373397

申请日：1995-01-17

申请人： John Langley ,  Kenneth Charles Symes

发明人： John Langley ,  Kenneth Charles Symes

IPC分类号： C12N9/98 ,  A01N25/10 ,  A01N25/22 ,  A01N25/28 ,  A01N33/18 ,  A01N43/90 ,  A01N47/30 ,  A01N57/16 ,  A61K9/14 ,  A61K9/16 ,  A61K9/50 ,  A61K47/32 ,  B01J13/10 ,  B01J13/12 ,  C08L33/02 ,  C08L101/00 ,  C09B67/02 ,  C11D3/37 ,  C11D3/386 ,  C11D7/42 ,  C12N11/04

CPC分类号： C12N11/04 ,  A01N25/10 ,  A01N25/28 ,  A01N33/18 ,  A01N43/90 ,  A01N47/30 ,  A01N57/16 ,  A61K9/1635 ,  A61K9/5026 ,  B01J13/10 ,  B01J13/125 ,  C11D3/3761 ,  C11D3/3769 ,  C11D3/38672 ,  Y10T428/2989 ,  Y10T428/2998

摘要： Release of an active ingredient can be controlled and the active ingredient can be protected from the environment during storage, by distributing it throughout a matrix containing a relatively large amount of polymeric material that is soluble and swellable in aqueous alkali but less soluble and swellable at a lower pH value and which is in the form of a dried oil-in-water emulsion of the polymer or a relatively insoluble partial salt of the polymer with a volatile amine, the full salt of the polymer being relatively soluble. The composition is of particular value for the protection of detergent enzymes.

摘要翻译： 可以控制活性成分的释放，并且通过将活性成分分散在含有相对大量聚合物材料的基质中，可以保护活性成分免受环境污染，所述基质在碱性水溶液中是可溶的和可溶胀的，但在 较低的pH值，并且其是聚合物的干水包油乳液或聚合物与挥发性胺的相对不溶的部分盐的形式，聚合物的全部盐相对可溶。 该组合物对于保护洗涤剂酶具有特别的价值。

公开(公告)号：US5631020A

公开(公告)日：1997-05-20

申请号：US468657

申请日：1995-06-06

申请人： Hiroaki Okada ,  Yasuaki Ogawa ,  Takatsuka Yashiki

发明人： Hiroaki Okada ,  Yasuaki Ogawa ,  Takatsuka Yashiki

IPC分类号： A61K9/66 ,  A61K9/16 ,  A61K9/50 ,  A61K9/52 ,  A61K38/05 ,  A61K38/08 ,  A61K38/09 ,  A61K38/22 ,  A61K38/33 ,  A61K38/37 ,  B01J13/02 ,  B01J13/12 ,  A61K9/14

CPC分类号： A61K9/5031 ,  A61K38/05 ,  A61K38/08 ,  A61K38/09 ,  A61K38/33 ,  A61K38/37 ,  A61K9/1647 ,  A61K9/1694 ,  A61K9/5089 ,  B01J13/02 ,  B01J13/125 ,  Y10S424/15 ,  Y10S514/80 ,  Y10S514/822 ,  Y10S514/843 ,  Y10S514/952 ,  Y10S514/963 ,  Y10S514/965 ,  Y10T428/2984 ,  Y10T428/2985 ,  Y10T428/2989

摘要： A microcapsule produced by preparing a water-in-oil emulsion comprising an inner aqueous layer containing said water-soluble drug and a drug retaining substance therefor and an oil layer containing a polymer substance, then thickening or solidifying said inner aqueous layer to a viscosity of not lower than about 5000 centiposes and finally subjecting the resulting emulsion to in water drying gives prolonged release of water-soluble drug.

摘要翻译： 通过制备包含含有所述水溶性药物的内层和其药物保留物质的油包水乳液和含有聚合物物质的油层而制备的微胶囊，然后将所述内层水溶液增稠或固化成粘度 不低于约5000厘泊，最后将所得乳液进行水中干燥，延长了水溶性药物的释放。

公开(公告)号：US5609886A

公开(公告)日：1997-03-11

申请号：US507079

申请日：1995-07-26

申请人： Henri Wantier ,  Fabienne Mathieu ,  Marc Baudrihaye ,  Dominique Delacroix

发明人： Henri Wantier ,  Fabienne Mathieu ,  Marc Baudrihaye ,  Dominique Delacroix

IPC分类号： A61K9/16 ,  B01J13/12 ,  A61K9/50 ,  B01J13/02 ,  B32B5/16

CPC分类号： A61K9/1647 ,  B01J13/12 ,  B01J13/125 ,  Y10S514/963 ,  Y10T428/2985

摘要： Microspheres which are a matrix of a biocompatible and biodegradable polymer which is soluble in an organic solvent which is immiscible in water, within which a water-soluble substance is uniformly distributed, and wherein the residual level of toxic solvent in the microspheres is lower than 1.5% by weight, progressively and continuously releases the substance over a period of at least 8 days when the microspheres are placed in an aqueous physiological environment, with a reduced or substantially absent first phase of accelerated release. A process for producing such microspheres is provided.

摘要翻译： 微球，其是可溶于在水中不混溶的有机溶剂的生物相容性和生物可降解聚合物的基质，其中水溶性物质均匀分布在其中，并且其中微球中的有毒溶剂的残留水平低于1.5 重量％，当微球体置于水性生理环境中时，在至少8天的时间内逐渐地和连续地释放物质，减少或基本上不存在第一阶段的加速释放。 提供了一种制备这种微球的方法。