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    HIGH VOLTAGE FIBER OPTIC SENSOR FOR THE MEASUREMENT OF AN ALTERNATING ELECTRIC FIELD
    132.
    发明申请
    HIGH VOLTAGE FIBER OPTIC SENSOR FOR THE MEASUREMENT OF AN ALTERNATING ELECTRIC FIELD 有权
    用于测量交流电场的高压光纤传感器

    公开(公告)号：US20160245846A1

    公开(公告)日：2016-08-25

    申请号：US15028271

    申请日：2014-10-09

    Applicant: CNR-CONSIGLIO NAZIONALE DELLE RICERCHE ,  LEDA SRL, LABORATORIO DI ELETTRODINAMICA AVANZATA

    Inventor： Gianluca GAGLIARDI ,  Fabrizio MARIGNETTI

    IPC: G01R15/24 ,  G01R29/12

    CPC classification number: G01R15/24 ,  G01R29/12

    Abstract: A method for measuring an alternating electric field is disclosed. The method includes realizing a first diffraction grating in a first location, in a core of a silica-based optical fiber, and measuring a peak reflection wavelength of the first diffraction grating. The method also includes positioning the optical fiber along a direction having a non-zero component of an electrical field generated by an alternating voltage to be measured, and coupling a substantially monochromatic light to said optical fiber surrounded by the electric field. The method further includes measuring a parameter dependent on a shift of the peak reflection wavelength due to intrinsic mechanical deformation or refractive index change of the material in which the optical fiber and the diffracting grating are realized due to the alternating electric field, and calculating a value of the electric field causing such a measured deformation or refractive index change.

    Abstract translation: 公开了一种用于测量交变电场的方法。 该方法包括在第一位置，在二氧化硅基光纤的芯中实现第一衍射光栅，并测量第一衍射光栅的峰值反射波长。 该方法还包括沿着具有由要测量的交流电压产生的电场的非零分量的方向定位光纤，以及将基本上单色的光耦合到由电场包围的所述光纤。 该方法还包括测量由于由于交变电场而实现光纤和衍射光栅的材料的固有机械变形或折射率变化引起的峰值反射波长的偏移的参数，并且计算值 的电场引起这种测量的变形或折射率变化。

    NEUTRALIZING RNA APTAMERS AGAINST PDGFBETA AND USES THEREOF IN THE THERAPY AND DIAGNOSIS OF HYPERPROLIFERATIVE DISEASES
    136.
    发明申请
    NEUTRALIZING RNA APTAMERS AGAINST PDGFBETA AND USES THEREOF IN THE THERAPY AND DIAGNOSIS OF HYPERPROLIFERATIVE DISEASES 有权
    对抗PDGFBETA的RNA APTAMA的中和及其在治疗中的应用及其诊断高增殖性疾病

    公开(公告)号：US20150275215A1

    公开(公告)日：2015-10-01

    申请号：US14433386

    申请日：2013-10-04

    Applicant: CONSIGLIO NAZIONALE DELLE RICERCHE

    Inventor： Laura Cerchia ,  Gerolama Condorelli ,  Vittorio De Franciscis

    IPC: C12N15/115

    CPC classification number: C12N15/115 ,  C12N2310/16 ,  C12N2310/322 ,  C12N2310/344 ,  C12N2310/3533

    Abstract: Nuclease-resistant RNA aptamers are provided which are capable of neutralizing PDGFRβ and are therefore useful in the diagnosis and/or therapy of PDGFRβ-associated and hyperproliferative-associated diseases, such as cancer and primary tumour metastasis. RNA aptamers provided herein include a modified synthetic RNA sequence wherein at least one pyrimidine residue is modified to 2′-fluoropyrimidine. Pharmaceutical compositions and diagnostic kits comprising RNA aptamers are also provided.

    Abstract translation: 提供了能够中和PDGFR和bgr的核酸酶抗性的RNA适体; 因此可用于诊断和/或治疗PDGFR和相关和过度增殖相关疾病，如癌症和原发性肿瘤转移。 本文提供的RNA适体包括修饰的合成RNA序列，其中至少一个嘧啶残基被修饰成2'-氟嘧啶。 还提供了包含RNA适体的药物组合物和诊断试剂盒。

    RECONSTRUCTION OF AN IMAGE OF AN OBJECT AT LEAST PARTIALLY HIDDEN BY A FLAME
    137.
    发明申请
    RECONSTRUCTION OF AN IMAGE OF AN OBJECT AT LEAST PARTIALLY HIDDEN BY A FLAME 有权
    重建由火焰部分隐藏的物体的图像

    公开(公告)号：US20150160613A1

    公开(公告)日：2015-06-11

    申请号：US14100775

    申请日：2013-12-09

    Applicant: Consiglio Nazionale delle Ricerche - CNR

    Inventor： Pietro FERRARO ,  Vittorio BIANCO ,  Melania PATURZO ,  Andrea FINIZIO ,  Lisa MICCIO ,  Massimiliano LOCATELLI ,  Eugenio PUGLIESE ,  Andrea Giovanni GELTRUDE ,  Anna PELAGOTTI ,  Pasquale POGGI ,  Riccardo MEUCCI

    IPC: G03H1/22

    CPC classification number: G03H1/0443 ,  G03H2001/0083 ,  G03H2001/0445 ,  G03H2001/2655 ,  G03H2210/63 ,  G03H2222/16

    Abstract: It is disclosed a system for reconstructing an image of an object hidden by a flame. The system comprises a laser source emitting an infrared radiation and a lensless, off-axis interferometric arrangement that divides the infrared radiation into an object beam and a reference beam. The object beam is enlarged and then irradiates the object, that scatters it. The reference beam is enlarged and then interferes with the scattered object beam, so as to create a hologram. The system comprises an infrared detector which detects the hologram and a processing unit which reconstructs the image of the object by numerically processing the hologram. The system therefore provides the object image based on digital holography at infrared wavelengths. Differently from known thermographic acquisition techniques, even if large portions of the object are hidden by the flame, the system allows to reconstruct an image of the whole object, with no blind areas.

    Abstract translation: 公开了一种用于重构由火焰隐藏的物体的图像的系统。 该系统包括发射红外辐射的激光源和将红外辐射分成物光束和参考光束的无透镜的离轴干涉装置。 物体光束被放大，然后照射物体，散射物体。 参考光束被放大，然后干扰散射的物体光束，以便产生全息图。 该系统包括检测全息图的红外检测器和通过数字处理全息图来重构物体的图像的处理单元。 因此，该系统基于红外波长的数字全息技术提供目标图像。 与已知的热成像采集技术不同，即使物体的大部分被火焰隐藏，系统允许重建整个物体的图像，没有盲区。

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