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    Method of identifying a gene associated with a disease or pathological condition of the disease
    134.
    发明授权
    Method of identifying a gene associated with a disease or pathological condition of the disease 有权

    公开(公告)号：US10787708B2

    公开(公告)日：2020-09-29

    申请号：US15647414

    申请日：2017-07-12

    Applicant: Macau University of Science and Technology

    Inventor： Liang Liu ,  Lai Han Leung ,  Ying Li ,  Xiao Jun Yao ,  Hu Dan Pan

    IPC: C12Q1/6883 ,  G16B30/00 ,  G16B50/00 ,  G16B20/20 ,  G16B5/00 ,  G16B15/00 ,  G16B40/20 ,  C12Q1/6869

    Abstract: A method of identifying a gene associated with a disease or pathological condition of the disease includes: a) obtaining a first group of exome sequences from a first population suffering from the disease or pathological condition and a second group of exome sequences from a second population not having the disease or pathological condition; b) identifying one or more variants in the first group by comparing it with the second group, and optionally with a public database, to generate a first set of variant data; c) applying a variant quality score calibration tool with a truth sensitivity threshold to remove false-positive variants having a sensitivity lower than the threshold and background variants from the first set of variant data so as to obtain a second set of variant data; d) removing synonymous variants from the second set of variant data to obtain a third set of variant data; and e) identifying one or more deleterious variants from the third set of variant data using a gene burden analysis, optionally generating a fourth set of variant data.

    System and method for controlling a converter circuit
    135.
    发明授权
    System and method for controlling a converter circuit 有权

    公开(公告)号：US10658936B2

    公开(公告)日：2020-05-19

    申请号：US15587543

    申请日：2017-05-05

    Applicant: Macau University of Science and Technology

    Inventor： Chuan Sun ,  Xiao Dong Li

    IPC: H02J1/10 ,  H02J3/38 ,  H02M3/335 ,  H02M7/04 ,  H02M7/44 ,  H02M3/04 ,  H02M3/337

    Abstract: Controlling operation of a converter circuit regulating power transfer between first and second voltage sources includes comparing a detected power value in the converter circuit with a power command value; determining a converter gain based on detected first and second voltage levels of the first and second voltage sources; and determining operation signals for transmitting to switches in the converter circuit during a steady state to control switching time and duration. When the detected power value differs from the power command value, the method includes determining values of two or more variables associated with adjustment of switching time and duration based on the detected first and second voltage levels; and determining operation signals to transmit to the switches during a power transition state based on the determined values of the two or more variables to adjust switching time and switching duration of the switches, thereby regulating power transition.

    METHOD AND PHARMACEUTICAL COMPOSITION FOR TREATING CANCER
    136.
    发明申请
    METHOD AND PHARMACEUTICAL COMPOSITION FOR TREATING CANCER 审中-公开

    公开(公告)号：US20200071695A1

    公开(公告)日：2020-03-05

    申请号：US16120606

    申请日：2018-09-04

    Applicant: Macau University of Science and Technology

    Inventor： Zhi-Hong Jiang ,  Tong-Meng Yan ,  Kai-Yue CAO

    IPC: C12N15/113 ,  A61P35/00

    Abstract: A method of treating a subject suffering from cancer includes administering an effective amount of a RNA molecule to the subject, wherein the RNA molecule is isolated or derived from a plant of the genus Taxus. A method of inhibiting growth or proliferation of cancer cells includes contacting cancer cells with the RNA molecule; and a pharmaceutical composition for treating cancer includes the RNA molecule and a pharmaceutically tolerable excipient. Also a double-stranded RNA molecule and a recombinant vector include the double-stranded RNA molecule.

    METHOD FOR IMPROVING CALCULATIONS OF SURFACE ROUGHNESS
    137.
    发明申请
    METHOD FOR IMPROVING CALCULATIONS OF SURFACE ROUGHNESS 审中-公开

    公开(公告)号：US20190251697A1

    公开(公告)日：2019-08-15

    申请号：US15894956

    申请日：2018-02-13

    Applicant: Macau University of Science and Technology

    Inventor： Zhanchuan CAI ,  Wei CAO

    IPC: G06T7/44 ,  G06T17/05 ,  G06F17/16 ,  G06F17/11

    Abstract: Example embodiments include a method that improves calculations of surface roughness that map a planetary surface. The method includes calculating a V-system matrix with a size of α×α in an interval [0,1]; transforming the V-system matrix into an orthogonal matrix; improving calculations of the surface roughness of the planetary surface by calculating the surface roughness of a digital elevation model generated from data captured from the planetary surface; and generating a map of the planetary surface based on the surface roughness.

    METHOD AND SYSTEM FOR SECURE ENCRYPTION
    138.
    发明申请
    METHOD AND SYSTEM FOR SECURE ENCRYPTION 审中-公开

    公开(公告)号：US20190238314A1

    公开(公告)日：2019-08-01

    申请号：US15880566

    申请日：2018-01-26

    Applicant: Macau University of Science and Technology

    Inventor： Zhanchuan CAI ,  Ting LAN

    IPC: H04L9/06 ,  H04L29/06

    CPC classification number: H04L9/0625 ,  H04L63/0428

    Abstract: A method executed by a computer system that transmits a multimedia content through a negative-base number. The method includes generating a binary sequence for the multimedia content, converting the binary sequence into a negative-base number, receiving the negative-base number, retrieving a negative base of the negative base number, calculating the binary sequence based on the negative-base number and the negative base, and obtaining the multimedia content based on the binary sequence.

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