公开(公告)号：US10932700B2

公开(公告)日：2021-03-02

申请号：US16924101

申请日：2020-07-08

Applicant: DexCom, Inc.

Inventor： Peter C. Simpson ,  James H. Brauker ,  Mark C. Brister ,  Paul V. Goode, Jr. ,  Apurv Ullas Kamath ,  Aarthi Mahalingam ,  Jack Pryor ,  Matthew D. Wightlin

IPC: A61B5/1495 ,  A61B5/1486 ,  A61B5/1468 ,  A61B5/1473 ,  A61B5/145 ,  A61B5/05 ,  A61B5/00 ,  A61B5/15 ,  A61B17/34 ,  A61M5/172 ,  A61M5/158 ,  A61M5/142

Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

公开(公告)号：US20210045667A1

公开(公告)日：2021-02-18

申请号：US17076714

申请日：2020-10-21

Applicant: DexCom, Inc.

Inventor： Apurv Ullas Kamath ,  Jack Pryor ,  Paul V. Goode, Jr. ,  James H. Brauker ,  Aarthi Mahalingam

IPC: A61B5/145 ,  A61B5/1495 ,  A61B5/1473 ,  A61B5/00 ,  A61B5/1486

Abstract: Systems and methods for processing sensor analyte data are disclosed, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. The sensor can be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. Reference data resulting from benchtop testing an analyte sensor prior to its insertion can be used to provide initial calibration of the sensor data. Reference data from a short term continuous analyte sensor implanted in a user can be used to initially calibrate or update sensor data from a long term continuous analyte sensor.

公开(公告)号：US10918317B2

公开(公告)日：2021-02-16

申请号：US16528379

申请日：2019-07-31

Applicant: DexCom, Inc.

Inventor： Jack Pryor ,  Apurv Ullas Kamath ,  Paul V. Goode, Jr. ,  James H. Brauker ,  Aarthi Mahalingam

IPC: A61B5/1473 ,  A61B5/1486 ,  A61B5/1468 ,  A61B5/1495 ,  A61B5/145 ,  A61B5/00

Abstract: Systems and methods for processing sensor analyte data are disclosed, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. The sensor can be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. Reference data resulting from benchtop testing an analyte sensor prior to its insertion can be used to provide initial calibration of the sensor data. Reference data from a short term continuous analyte sensor implanted in a user can be used to initially calibrate or update sensor data from a long term continuous analyte sensor.

公开(公告)号：US20210038136A1

公开(公告)日：2021-02-11

申请号：US17076730

申请日：2020-10-21

Applicant: DexCom, Inc.

Inventor： Apurv Ullas Kamath ,  Jack Pryor ,  Paul V. Goode, JR. ,  James H. Brauker ,  Aarthi Mahalingam

IPC: A61B5/145 ,  A61B5/1486 ,  A61B5/00 ,  A61B5/1473 ,  A61B5/1495

Abstract: Systems and methods for processing sensor analyte data are disclosed, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. The sensor can be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. Reference data resulting from benchtop testing an analyte sensor prior to its insertion can be used to provide initial calibration of the sensor data. Reference data from a short term continuous analyte sensor implanted in a user can be used to initially calibrate or update sensor data from a long term continuous analyte sensor.

公开(公告)号：US20210022653A1

公开(公告)日：2021-01-28

申请号：US17035478

申请日：2020-09-28

Applicant: DexCom, Inc.

Inventor： James H. Brauker ,  Robert J. Boock ,  Monica A. Rixman ,  Peter C. Simpson ,  Mark C. Brister ,  Mark C. Shults

IPC: A61B5/1486 ,  A61B5/145 ,  A61B5/00 ,  C12Q1/00 ,  G01N33/543 ,  G01N33/66

Abstract: Biointerface membranes are provided which can be utilized with implantable devices, such as devices for the detection of analyte concentrations in a biological sample. More particularly, methods for monitoring glucose levels in a biological fluid sample using an implantable analyte detection device incorporating such membranes are provided.

公开(公告)号：US10898114B2

公开(公告)日：2021-01-26

申请号：US16691107

申请日：2019-11-21

Applicant: DexCom, Inc.

Inventor： Apurv Ullas Kamath ,  James H. Brauker ,  Paul V. Goode, Jr. ,  Aarthi Mahalingam ,  Jack Pryor

IPC: A61B5/1486 ,  A61B5/1468 ,  A61B5/1473 ,  A61B5/1495 ,  A61B5/145 ,  A61B5/00

Abstract: Systems and methods for processing sensor analyte data are disclosed, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. The sensor can be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. Reference data resulting from benchtop testing an analyte sensor prior to its insertion can be used to provide initial calibration of the sensor data. Reference data from a short term continuous analyte sensor implanted in a user can be used to initially calibrate or update sensor data from a long term continuous analyte sensor.

公开(公告)号：US10860687B2

公开(公告)日：2020-12-08

申请号：US15632181

申请日：2017-06-23

Applicant: DexCom, Inc.

Inventor： Eric Cohen ,  Brian Christopher Smith ,  Michael Robert Mensinger ,  Rian Draeger ,  Katherine Yerre Koehler ,  Leif N. Bowman ,  David Price ,  Shawn Larvenz ,  Eli Reihman

IPC: G06F19/00 ,  A61B5/145 ,  A61B5/00 ,  A61B5/1495 ,  A61B5/02 ,  G16H40/63 ,  G16H15/00 ,  H04Q9/00

Abstract: Methods and apparatus, including computer program products, are provided for remote monitoring. In some example implementations, there is provided a method. The method may include receiving, at a remote monitor, a notification message representative of an event detected, by a server, from analyte sensor data obtained from a receiver monitoring an analyte state of a host; presenting, at the remote monitor, the notification message to activate the remote monitor, wherein the remote monitor is configured by the server to receive the notification message to augment the receiver monitoring of the analyte state of the host; accessing, by the remote monitor, the server, in response to the presenting of the notification message; and receiving, in response to the accessing, information including at least the analyte sensor data. Related systems, methods, and articles of manufacture are also disclosed.

公开(公告)号：US20200375515A1

公开(公告)日：2020-12-03

申请号：US16998841

申请日：2020-08-20

Applicant: DexCom, Inc.

Inventor： Mark Shults ,  James H. Brauker ,  Victoria Carr-Brendel ,  Mark Tapsak ,  Dubravka Markovic

IPC: A61B5/1486 ,  A61B5/145 ,  A61L31/10 ,  A61L31/14 ,  A61L31/16

Abstract: A biointerface membrane for an implantable device including a nonresorbable solid portion with a plurality of interconnected cavities therein adapted to support tissue ingrowth in vivo, and a bioactive agent incorporated into the biointerface membrane and adapted to modify the tissue response is provided. The bioactive agents can be chosen to induce vascularization and/or prevent barrier cell layer formation in vivo, and are advantageous when used with implantable devices wherein solutes are transported across the device-tissue interface.

公开(公告)号：US20200374699A1

公开(公告)日：2020-11-26

申请号：US16990853

申请日：2020-08-11

Applicant: DexCom, Inc.

Inventor： Kenneth San Vicente ,  Indrawati Gauba ,  Siddharth Waichal ,  Andrew Walker

IPC: H04W12/06 ,  A61B5/145 ,  A61B5/1495 ,  H04W4/80 ,  H04W4/70 ,  H04W76/14 ,  H04W12/04 ,  A61B5/00 ,  H04B7/26 ,  H04L29/06

Abstract: Systems and methods for continuous measurement of an analyte in a host are provided. The system generally includes a continuous analyte sensor configured to continuously measure a concentration of analyte in a host and a sensor electronics module physically connected to the continuous analyte sensor during sensor use, wherein the sensor electronics module is further configured to directly wirelessly communicate sensor information to one or more display devices. Establishment of communication between devices can involve using a unique identifier associated with the sensor electronics module to authenticate communication. Times tracked at the sensor electronics module and the display module can be at different resolutions, and the different resolutions can be translated to facilitate communication. In addition, the frequency of establishing communication channels between the sensor electronics module and the display devices can vary depending upon whether reference calibration information is being updated.

公开(公告)号：US20200330684A1

公开(公告)日：2020-10-22

申请号：US16852369

申请日：2020-04-17

Applicant: DexCom, Inc.

Inventor： John Michael Dobbles ,  Apurv Ullas Kamath ,  Aarthi Mahalingam ,  James H. Brauker

IPC: A61M5/172 ,  A61B5/145 ,  A61M5/142 ,  A61M11/00 ,  A61M15/00 ,  G16H40/63 ,  G16H20/17 ,  A61M35/00 ,  A61M5/20

Abstract: Systems and methods for integrating a continuous glucose sensor 12, including a receiver 14, a medicament delivery device 16, a controller module, and optionally a single point glucose monitor 18 are provided. Integration may be manual, semi-automated and/or fully automated.