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    DENTIFRICE COMPOSITION
    152.
    发明申请
    DENTIFRICE COMPOSITION 有权
    DENTIFRICE组成

    公开(公告)号：US20120045402A1

    公开(公告)日：2012-02-23

    申请号：US13266998

    申请日：2010-05-25

    Applicant: Andre Morgan ,  Venda Porter ,  Melissa Martinetti ,  Michael Prencipe

    Inventor： Andre Morgan ,  Venda Porter ,  Melissa Martinetti ,  Michael Prencipe

    IPC: A61K8/58 ,  A61Q11/00 ,  A61K8/69

    CPC classification number: A61Q11/00 ,  A61K8/27 ,  A61K8/365 ,  A61K8/731

    Abstract: Disclosed are dentifrice compositions comprising an orally acceptable vehicle and at least one source of metal ions in a polymer matrix, the metal being selected from zinc, stannous, copper or combinations thereof, the at least one source of metal ions comprising from 10 to 75 wt % of the total weight of the polymer matrix and the at least one source of metal ions, and wherein the dentifrice composition comprises less than 10 wt % water based on the total weight of the dentifrice composition. Also disclosed is a method of stabilizing at least one source of metal ions in a dentifrice compositions.

    Abstract translation: 公开了包含口腔可接受的载体和聚合物基质中的至少一种金属离子源的洁牙剂组合物，所述金属选自锌，亚锡，铜或其组合，所述至少一种金属离子源包含10至75wt 基于聚合物基质和至少一种金属离子源的总重量的百分比，并且其中所述洁牙剂组合物包含基于洁齿剂组合物的总重量小于10重量％的水。 还公开了一种在洁牙剂组合物中稳定至少一种金属离子源的方法。

    Dental whitening method
    153.
    发明授权
    Dental whitening method 失效
    牙齿美白方法

    公开(公告)号：US07601002B2

    公开(公告)日：2009-10-13

    申请号：US10811724

    申请日：2004-03-29

    Applicant: Nebojsa Milanovich ,  Ryan B. Cameron ,  John P. Curtis ,  Ravi Subramanyam ,  Michael Prencipe

    Inventor： Nebojsa Milanovich ,  Ryan B. Cameron ,  John P. Curtis ,  Ravi Subramanyam ,  Michael Prencipe

    IPC: A61C5/00

    CPC classification number: A61K8/22 ,  A61K2800/88 ,  A61Q11/00

    Abstract: A method for whitening a dental surface comprises nonsimultaneously applying a whitening composition to the surface, the whitening composition comprising at least one orally acceptable peroxy compound, and directing a volume of up to about 2.5 ml of an atomized activating composition on to the surface, wherein the activating composition comprises, in the volume so directed, a peroxy compound activating effective amount of at least one orally acceptable basifying agent, and wherein applying the whitening composition and directing the activating composition are separated by an interval not greater than a peroxy compound activating effective interval. The atomized composition can be directed on to the dental surface before or after application of the whitening composition.

    Abstract translation: 美白牙齿表面的方法包括将美白组合物同时施用于表面，美白组合物包含至少一种口服可接受的过氧化合物，并将一定体积的至多约2.5ml雾化的活化组合物引导至表面，其中 活化组合物包括在如此定向的体积中活化有效量的至少一种口服可接受的碱化剂的过氧化合物，并且其中施用所述增白组合物并引导所述活化组合物以不大于过氧化合物活化的有效间隔 间隔。 雾化组合物可以在施用美白组合物之前或之后被引导到牙齿表面。

    Oral Care Compositions Containing a Mixed Tocopherol Component
    156.
    发明申请
    Oral Care Compositions Containing a Mixed Tocopherol Component 审中-公开
    含有混合生育酚成分的口腔护理组合物

    公开(公告)号：US20080241117A1

    公开(公告)日：2008-10-02

    申请号：US11695129

    申请日：2007-04-02

    Applicant: Abdul Gaffar ,  Sarita V. Mello ,  Michael Prencipe

    Inventor： Abdul Gaffar ,  Sarita V. Mello ,  Michael Prencipe

    IPC: A61K31/355

    CPC classification number: A61K8/678 ,  A61Q11/00

    Abstract: An oral care composition, such as a dentifrice composition, which provides enhanced anti-gingivitis efficacy is disclosed. The composition includes a tocopherol component which consists of about 10% to about 90% of gamrnma tocopherol, with the balance of the components selected from alpha tocopherol, beta tocopherol, delta tocopherol, and mixtures thereof.

    Abstract translation: 公开了提供增强的抗牙龈炎功效的口腔护理组合物，例如洁齿剂组合物。 组合物包括由约10％至约90％的游离氨基酸生育酚组成的生育酚组分，其余组分选自α-生育酚，β-生育酚，δ-生育酚及其混合物。

    ANTI-STAINING ANTIBACTERIAL DENTIFRICE
    157.
    发明申请
    ANTI-STAINING ANTIBACTERIAL DENTIFRICE 审中-公开
    抗生素抗菌素

    公开(公告)号：US20080199412A1

    公开(公告)日：2008-08-21

    申请号：US12100922

    申请日：2008-04-10

    Applicant: Nebojsa Milanovich ,  Abdul Gaffar ,  Michael Prencipe ,  Thomas Boyd

    Inventor： Nebojsa Milanovich ,  Abdul Gaffar ,  Michael Prencipe ,  Thomas Boyd

    IPC: A61K8/55 ,  A61K8/69 ,  A61Q11/00

    CPC classification number: A61K8/33 ,  A61K8/81 ,  A61K8/8164 ,  A61K2800/52 ,  A61Q11/00

    Abstract: An anti-staining, antibacterial dentifrice comprises an anti-staining effective amount of an orally acceptable polymer or copolymer that comprises a plurality of monomeric groups of formula (I) wherein (a) one of A and A′ is hydrogen and the other is a moiety (X)n(R)m, (b) n in individual such moieties is independently 0 or 1, (c) linking groups X if present independently comprise an oxygen, sulfur, nitrogen, phosphorus or silicon atom, (d) where n is 0, m is 1, and where n is 1, m is independently an integer from 1 to 3 as determined by X, (e) terminal groups R are independently hydrogen or C1-18 organic radicals, and (t) M and M′ are independently selected from hydrogen, alkali metal and ammonium; said polymer or copolymer having an average molecular weight of at least about 1,000. The dentifrice further comprises an antibacterial effective amount of an orally acceptable halogenated diphenylether antibacterial agent, and an antibacterial enhancing effective amount of an orally acceptable polyvinylmethylether/maleic anhydride copolymer.

    Abstract translation: 抗污染的抗菌洁齿剂包括抗染色有效量的口服可接受的聚合物或共聚物，其包含多个式（I）的单体基团，其中（a）A和A'之一是氢，另一个是 部分（X）单独的这些部分中的（b）n独立地为0或1，（c）连接基团X（如果存在）独立地包含氧 ，硫，氮，磷或硅原子，（d）其中n为0，m为1，n为1，m为独立地为1至3的整数，（e）端基R独立地为 氢或C 1-18个有机基团，和（t）M和M'独立地选自氢，碱金属和铵; 所述聚合物或共聚物的平均分子量至少约为1,000。 洁齿剂还包含抗菌有效量的口服可接受的卤化二苯醚抗菌剂，以及抗菌增强有效量的口服可接受的聚乙烯基甲基醚/马来酸酐共聚物。

    Dual Component Dental Composition Containing Enzyme
    158.
    发明申请
    Dual Component Dental Composition Containing Enzyme 审中-公开
    含有酶的双组分牙科组合物

    公开(公告)号：US20080152601A1

    公开(公告)日：2008-06-26

    申请号：US12042870

    申请日：2008-03-05

    Applicant: Malcolm Williams ,  Michael Prencipe ,  James G. Masters

    Inventor： Malcolm Williams ,  Michael Prencipe ,  James G. Masters

    IPC: A61K8/66

    CPC classification number: A61Q11/00 ,  A61K8/66 ,  A61K2800/88

    Abstract: A two component desensitizing dentifrice composition is disclosed which comprises a first dentifrice component containing an enzyme such as papain and a second dentifrice component containing an ionic surfactant such as sodium lauryl sulfate, the first and second dentifrice components being maintained separate from the other until dispensed for application to teeth whereby enzyme activity is maintained with improved dentifrice foaming characteristics.

    Abstract translation: 公开了一种双组分脱敏洁牙剂组合物，其包含含有酶如木瓜蛋白酶的第一洁齿剂组分和含有离子表面活性剂如十二烷基硫酸钠的第二洁齿剂组分，第一和第二洁齿剂组分彼此分离直到分配 应用于牙齿，由此保持酶活性并提高洁牙剂发泡特性。

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