Silodosin intermediate and preparation method therefor
    151.
    发明授权
    Silodosin intermediate and preparation method therefor 有权
    西洛昔辛中间体及其制备方法

    公开(公告)号:US09394251B2

    公开(公告)日:2016-07-19

    申请号:US14365638

    申请日:2012-07-27

    Abstract: Disclosed are a silodosin intermediate and a preparation method thereof. The silodosin intermediate has the structure shown by the formula (A). X is hydrogen or bromide and R1 is hydrogen. The formyl group may be a group having the structure shown by the formula I. R7 is a protecting group of carboxyl, and R2 is 3-hydroxypropyl or a group having the structure shown by the formula II. W is a protecting group of hydroxyl. A compound of the formula (A) according to the present invention may further be used for preparing a compound having the structure shown by the formula (D). By means of the intermediate and the preparation method therefor provided by the present invention, high-purity optically pure silodosin can be obtained, and the optical purity is above 99%.

    Abstract translation: 公开了一种西洛多辛中间体及其制备方法。 西洛德辛中间体具有式(A)所示的结构。 X是氢或溴,R 1是氢。 甲酰基可以是具有式I所示结构的基团.R 7是羧基的保护基,R 2是3-羟丙基或具有式II所示结构的基团。 W是羟基的保护基。 根据本发明的式(A)化合物还可用于制备具有式(D)所示结构的化合物。 通过本发明提供的中间体及其制备方法,可以得到高纯度的光学纯的芝麻酮,光学纯度高于99%。

    Network balancing procedure that includes redistributing flows on arcs incident on a batch of vertices
    153.
    发明授权
    Network balancing procedure that includes redistributing flows on arcs incident on a batch of vertices 有权
    网络平衡过程,包括重新分布在一组顶点上的弧上的流

    公开(公告)号:US09003419B2

    公开(公告)日:2015-04-07

    申请号:US12512246

    申请日:2009-07-30

    CPC classification number: H04L47/125

    Abstract: A representation of a flow network having vertices connected by arcs is provided. The vertices include a first set of vertices that provide flow to a second set of vertices over arcs connecting the first set and second set of vertices. A balancing procedure in the network is performed that includes redistributing flows on arcs incident on the second set of vertices. The balancing procedure includes selecting a batch of the vertices in the second set, and redistributing flows on arcs incident on the selected batch of vertices. The selecting and redistributing are repeated for other batches of vertices in the second set.

    Abstract translation: 提供了具有由弧连接的顶点的流网络的表示。 顶点包括第一组顶点,其在连接第一组和第二组顶点的弧上提供流向第二组顶点的流。 执行网络中的平衡过程,其包括重新分布入射在第二组顶点的弧上的流。 平衡过程包括选择第二组中的一批顶点,并重新分布入侵在所选批次顶点上的圆弧上的流。 对第二组中的其他批次的顶点重复选择和重新分配。

    Hierarchical cluster determination based on subgraph density
    154.
    发明授权
    Hierarchical cluster determination based on subgraph density 有权
    基于子图密度的分层聚类确定

    公开(公告)号:US08971665B2

    公开(公告)日:2015-03-03

    申请号:US13562598

    申请日:2012-07-31

    CPC classification number: G06K9/6219

    Abstract: Densest subgraphs of a graph are determined. The graph includes vertices and edges interconnecting the vertices. Each edge connects two of the vertices and has a weight. The vertices and the edges form subgraphs from which the densest subgraphs are determined as those subgraphs having densities greater than a threshold. Clusters at levels of a hierarchy are determined based on the densest subgraphs. Each cluster includes a set of the vertices and a set of the edges of the graph. Each level corresponds to a different density of the clusters. The hierarchy is ordered from a most-dense level of the clusters to a least-dense level of the clusters.

    Abstract translation: 确定曲线图的发光子图。 该图包括互连顶点的顶点和边。 每个边缘连接两个顶点并具有重量。 顶点和边缘形成子图,最密集子图确定为密度大于阈值的子图。 根据最密集的子图确定层次结构级别的群集。 每个群集包括一组顶点和一组图的边。 每个级别对应于簇的不同密度。 层次结构从集群的最密集级别排列到集群的最低密度级别。

    Coordination of tasks executed by a plurality of threads using two synchronization primitive calls
    155.
    发明授权
    Coordination of tasks executed by a plurality of threads using two synchronization primitive calls 有权
    使用两个同步原语调用协调由多个线程执行的任务

    公开(公告)号:US08904406B2

    公开(公告)日:2014-12-02

    申请号:US12512256

    申请日:2009-07-30

    CPC classification number: G06F9/52 G06F9/522

    Abstract: To coordinate tasks executed by a plurality of threads that each includes plural task sections, a call of a mark primitive to mark a first point after a first of the plural task sections is provided. Also, a call of a second primitive is provided to indicate that a second of the plural task sections is not allowed to begin until after the plurality of threads have each reached the first point.

    Abstract translation: 为了协调由包括多个任务部分的多个线程执行的任务,提供了在多个任务部分中的第一个之后标记第一点的标记原语的调用。 此外,提供第二原语的调用以指示在多个线程各自到达第一点之后,多个任务部分中的第二个不允许开始。

    Multi-input, multi-output-per-input user-defined-function-based database operations
    156.
    发明授权
    Multi-input, multi-output-per-input user-defined-function-based database operations 有权
    多输入,多输出输入的基于用户定义功能的数据库操作

    公开(公告)号:US08805870B2

    公开(公告)日:2014-08-12

    申请号:US13192373

    申请日:2011-07-27

    CPC classification number: G06F17/30415

    Abstract: The current application discloses a database management system that provides multiple-input, multiple-output-per-input user-defined-function-based operations. The database management system comprises at least one processor and electronic memory, a database-query processor, executed on a computer processor controlled by computer instructions stored in a computer-readable memory, that makes multiple calls to a multiple-input, multiple-output-per-input user-defined-function, in each call transmitting a next input to the multiple-input, multiple-output-per-input user-defined-function, and the multiple-input, multiple-output-per-input user-defined-function, executed on a computer processor controlled by computer instructions stored in a computer-readable memory, that uses three different memory buffers, the contents of which are maintained for three different time periods, to compute and return to the database-query processor multiple outputs in response to at least one of the multiple inputs.

    Abstract translation: 当前的应用公开了一种数据库管理系统,其提供多输入多输出用户定义的基于功能的操作。 数据库管理系统包括至少一个处理器和电子存储器,数据库查询处理器,其在由存储在计算机可读存储器中的计算机指令控制的计算机处理器上执行,其对多输入多输出 - 每个输入用户定义的功能,在每次呼叫中传送下一个输入到多输入多输出用户定义函数,以及多输入多输出用户定义函数, 定义的功能,在由存储在计算机可读存储器中的计算机指令控制的计算机处理器上执行,其使用三个不同的存储器缓冲器,其内容维持三个不同的时间段,以计算并返回到数据库查询处理器 多个输出响应多个输入中的至少一个。

    SPATIAL SAMPLING IMPROVEMENT FOR LIST-MODE PET ACQUISITION USING PLANNED TABLE/GANTRY MOVEMENT
    158.
    发明申请
    SPATIAL SAMPLING IMPROVEMENT FOR LIST-MODE PET ACQUISITION USING PLANNED TABLE/GANTRY MOVEMENT 审中-公开
    使用计划表/ GANTRY运动的列表模式PET获取的空间抽样改进

    公开(公告)号:US20140107476A1

    公开(公告)日:2014-04-17

    申请号:US14124351

    申请日:2012-06-01

    CPC classification number: A61B6/037 A61B6/04 A61B6/5205 A61B6/547 G01T1/1647

    Abstract: A PET apparatus includes a detector array including individual detectors which receive radiation events from an imaging region. A movement controller controls at least one of relative longitudinal movement between a subject support and the detector array and circumferential movement between the detector array and the subject. A time stamp processor assigns a time stamp to each received radiation event. A list mode event storage buffer stores time stamped events. An event verification processor screens for coincidentally received radiation events, locations at which each pair of corresponding coincidentally received events defining a line of response. A reconstruction processor reconstructs valid events into an image representation of the imaging region.

    Abstract translation: PET装置包括检测器阵列,其包括从成像区域接收辐射事件的各个检测器。 运动控制器控制受检者支架和检测器阵列之间的相对纵向移动中的至少一个以及检测器阵列和被检体之间的周向运动。 时间戳处理器为每个接收到的辐射事件分配时间戳。 列表模式事件存储缓冲区存储时间戳事件。 事件验证处理器屏蔽偶然接收的辐射事件,每对对应的巧合接收事件定义响应行的位置。 重建处理器将有效事件重建成成像区域的图像表示。

    Methods and apparatus using range queries for multi-dimensional data in a database
    159.
    发明授权
    Methods and apparatus using range queries for multi-dimensional data in a database 有权
    在数据库中使用多维数据的范围查询的方法和装置

    公开(公告)号:US08688723B2

    公开(公告)日:2014-04-01

    申请号:US12241305

    申请日:2008-09-30

    CPC classification number: G06F17/30424 G06F17/30592

    Abstract: Embodiments include methods, apparatus, and systems for using range queries in multidimensional data in a database. One embodiment is a method that defines a query box from a search for multidimensional data in a database. The method examines an intersection between a Z-interval and the query box by decomposing the Z-interval into hyper-boxes that are also Z-intervals in Z space. Items in the query box that match the search are discovered.

    Abstract translation: 实施例包括在数据库中的多维数据中使用范围查询的方法,装置和系统。 一个实施例是一种从数据库中的多维数据搜索定义查询框的方法。 该方法通过将Z间隔分解为Z空间中也是Z间隔的超盒子来检查Z间隔和查询框之间的交集。 发现与查询匹配的查询框中的项目。

    Hierarchical cluster determination based on subgraph density
    160.
    发明申请
    Hierarchical cluster determination based on subgraph density 有权
    基于子图密度的分层聚类确定

    公开(公告)号:US20140037227A1

    公开(公告)日:2014-02-06

    申请号:US13562598

    申请日:2012-07-31

    CPC classification number: G06K9/6219

    Abstract: Densest subgraphs of a graph are determined. The graph includes vertices and edges interconnecting the vertices. Each edge connects two of the vertices and has a weight. The vertices and the edges form subgraphs from which the densest subgraphs are determined as those subgraphs having densities greater than a threshold. Clusters at levels of a hierarchy are determined based on the densest subgraphs. Each cluster includes a set of the vertices and a set of the edges of the graph. Each level corresponds to a different density of the clusters. The hierarchy is ordered from a most-dense level of the clusters to a least-dense level of the clusters.

    Abstract translation: 确定曲线图的发光子图。 该图包括互连顶点的顶点和边。 每个边缘连接两个顶点并具有重量。 顶点和边缘形成子图,最密集子图确定为密度大于阈值的子图。 根据最密集的子图确定层次结构级别的群集。 每个群集包括一组顶点和一组图的边。 每个级别对应于簇的不同密度。 层次结构从集群的最密集级别排列到集群的最低密度级别。

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