公开(公告)号：US20190292579A1

公开(公告)日：2019-09-26

申请号：US16333665

申请日：2017-09-18

Applicant: Aaron Kurt Neumann ,  Matthew S Graus ,  Jerilyn A Timlin

Inventor： Aaron Kurt Neumann ,  Matthew S Graus ,  Jerilyn A Timlin

IPC: C12Q1/04 ,  G01N21/64

Abstract: Methods and apparatus for rapid, culture free pathogen detection. The methods utilize optical spectroscopy techniques to identify and/or characterize pathogens in a sample via the detection of unique properties and/or analytes that are specific to particular pathogens.

公开(公告)号：US10381737B2

公开(公告)日：2019-08-13

申请号：US15706483

申请日：2017-09-15

Applicant: Youssef Antoine Tawk ,  Christos G. Christodoulou ,  Joseph Costantine ,  Michel Chahoud ,  Marwan Fadous

Inventor： Youssef Antoine Tawk ,  Christos G. Christodoulou ,  Joseph Costantine ,  Michel Chahoud ,  Marwan Fadous

IPC: H01Q1/36 ,  H01Q11/08 ,  H01Q15/16 ,  H01Q19/10

Abstract: The present invention provides an antenna miniaturized topology that is based on the implementation of a conductive loading on a quadrifilar helix antenna. This may be achieved by connecting the tip of the four helical arms to end members which may be circular planar conductors. The miniaturization of the antenna may be further enhanced by incorporating a dielectric material in the space between the four arms.

公开(公告)号：US10317212B1

公开(公告)日：2019-06-11

申请号：US15984048

申请日：2018-05-18

Applicant: STC.UNM

Inventor： Jean-Claude Diels ,  Ladan Arissian ,  Matthias Lenzner ,  James Hendrie

IPC: G01C19/66 ,  G01C19/70

Abstract: Apparatus, systems, and methods associated with enhancement of phase response of intracavity phase interferometers are applicable in a variety of applications.

公开(公告)号：US10278649B2

公开(公告)日：2019-05-07

申请号：US15531135

申请日：2015-11-24

Applicant: STC.UNM

Inventor： Majeed M. Hayat ,  Sanjay Krishna ,  Sebastian Eugenio Godoy ,  David A. Ramirez

IPC: G06K9/00 ,  A61B5/00 ,  A61B5/01 ,  G06F19/00 ,  G06T7/62 ,  G06T7/68 ,  G06T7/277 ,  G06T7/13 ,  G06T7/174 ,  G06T7/90 ,  G16H50/20 ,  G06K9/62 ,  G06T7/00 ,  G06T7/40

Abstract: A technique for classifying lesions as malignant or benign is disclosed. The technique can include: cooling an area of skin including a lesion of a patient to initiate a warm-up process; receiving a temporal sequence of thermal images of the area of skin representing a thermal recovery of the area of skin, the temporal sequence of thermal images generated by an infrared camera; generating a temporal profile of the thermal recovery based on the temporal sequence of thermal images; analyzing temporal statistical properties of the temporal profile; determining a malignancy probability that the lesion is malignant based on an analysis of the temporal profile, wherein the determining includes extracting one or more statistical features based on continuous-time stochastic signals in the sequence of thermal images; and classifying the lesion based on the malignancy probability.

公开(公告)号：US10256546B1

公开(公告)日：2019-04-09

申请号：US15148584

申请日：2016-05-06

Applicant: Joseph Costantine ,  Christos G. Christodoulou ,  Youssef Antoine Tawk ,  Christoph Benedikt Lukas Karl ,  Nicolas Nik Lee ,  Ignacio Maqueda Jimenez ,  Sergio Pellegrino ,  Maria Sakovsky

Inventor： Joseph Costantine ,  Christos G. Christodoulou ,  Youssef Antoine Tawk ,  Christoph Benedikt Lukas Karl ,  Nicolas Nik Lee ,  Ignacio Maqueda Jimenez ,  Sergio Pellegrino ,  Maria Sakovsky

IPC: H01Q11/08 ,  H01Q1/08 ,  H01Q1/28

Abstract: An antenna having a body that includes a plurality of rigid sections separated by a plurality of flexible sections and at least one conductor attached to the rigid and flexible sections. The flexible sections forming hinges that connect rigid sections together to permit the body to be configured into a conical configuration from a substantially flat trapezoid configuration.

公开(公告)号：US10183032B2

公开(公告)日：2019-01-22

申请号：US15691977

申请日：2017-08-31

Applicant: Ball State Innovation Corporation ,  STC.UNM

Inventor： Susan A. McDowell ,  Robert E. Sammelson ,  Larry A. Sklar ,  Mark K. Haynes

IPC: A61K31/415 ,  A61K31/63 ,  A61K31/635

Abstract: The present disclosure relates to molecules that function as selective modulators (i.e., inhibitors and agonists) of the Ras-homologous (Rho) family of small GTPases and, in particular, CDC42 GTPase, and their use to treat bacterial infection including systemic infection from sources such as Staphylococcus aureus and Streptococcus pyogenes.

公开(公告)号：US10174042B2

公开(公告)日：2019-01-08

申请号：US15348756

申请日：2016-11-10

Applicant: University of Florida Research Foundation, Inc. ,  STC.UNM

Inventor： David G. Whitten ,  Kirk S. Schanze ,  Anand Parthasarathy ,  Eunkyung Ji ,  Motokatsu Ogawa ,  Thomas S. Corbitt ,  Dimitri Dascier ,  Ying Wang ,  Linnea K. Ista ,  Eric H. Hill

IPC: C07D487/08 ,  C07C217/14 ,  C07C309/11 ,  C07C217/20 ,  C07C309/24 ,  C07D333/16 ,  C08G61/02 ,  C08G75/00 ,  C08G61/12

Abstract: The present disclosure provides novel poly(phenylene ethynylene) (PPE) compounds, methods for synthesizing these compounds, and materials and substances incorporating these compounds. The various PPEs show antibacterial, antiviral and antifungal activity.

公开(公告)号：US10086010B2

公开(公告)日：2018-10-02

申请号：US15126777

申请日：2015-03-17

Applicant: STC.UNM ,  Hiroshi Ide

Inventor： Yoshihiro Matsumoto ,  Alan Edward Tomkinson ,  Hiroshi Ide

IPC: A01N43/04 ,  A61K31/70 ,  A61K31/7072 ,  A61K31/513 ,  A61P35/00 ,  A61K45/06 ,  A61K31/7064 ,  A61K31/706 ,  A61K31/7068

Abstract: In one embodiment, the invention provides a method of treating a subject who suffers from a neoplasm (including a cancer such as a radiotherapeutic-resistant cancer) by administering to the subject a therapeutically effective amount of (a) 5-formyl-2′-deoxyuridine (fdU or foUdR) or a 5-formyl-2′-deoxyuridine derivative, optionally in combination with 5-hydroxy-2′-deoxyuridine (hUdR); and (b) at least one composition selected from the group consisting of either 5-fluorouracil (5-FU), a 5-FU prodrug (e.g. 5-fluoro-2′-deoxyuridine (FdU)) or 5-FU metabolite. In a preferred embodiment, a subject who suffers from colorectal cancer (CRC) or metastatic colorectal cancer (mCRC) is treated with a therapeutically-effective amount of fdU and either 5-FU or the 5-FU prodrug 5-fluoro-2′-deoxyuridine (FdU). Related pharmaceutical compositions are also provided.

公开(公告)号：US20180264220A1

公开(公告)日：2018-09-20

申请号：US15753887

申请日：2016-08-22

Applicant: STC.UNM

Inventor： Hans Fredrick Hurt

IPC: A61M16/06 ,  A61M39/08

CPC classification number: A61M16/0605 ,  A61J15/0003 ,  A61J15/0061 ,  A61M16/00 ,  A61M16/06 ,  A61M16/0672 ,  A61M16/0683 ,  A61M16/0688 ,  A61M39/08 ,  A61M2202/0208 ,  A61M2210/0618

Abstract: A medical device sealing system for use with a positive pressure ventilation mask and a nasal cannula. The system includes a plurality of sealing elements. The sealing elements include an opening sized to receive a nasal cannula. The sealing elements are spaced apart a distance sufficient to cause the sealing elements to engage the edges of a mask and to form a seal between the edges of a mask and a patient.

公开(公告)号：US10049469B2

公开(公告)日：2018-08-14

申请号：US15103977

申请日：2014-12-15

Applicant: STC.UNM

Inventor： Cesar Carranza ,  Marios Stephanou Pattichis ,  Daniel Llamocca Obregon

IPC: G06T11/00 ,  G06F17/14 ,  G06K9/00

Abstract: A fast and a scalable approach for computing the forward and inverse DPRT that uses: (i) a parallel array of fixed-point adder trees to compute the additions, (ii) circular shift registers to remove the need for accessing external memory components, (iii) an image block-based approach to DPRT computation that can fit the proposed architecture to available resources, and (iv) fast transpositions that are computed in one or a few clock cycles that do not depend on the size of the input image.