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公开(公告)号：US20060275225A1
公开(公告)日：2006-12-07
申请号：US11403732
申请日：2006-04-13
Applicant: Michael Prencipe , Suman Chopra , Joseph Norris , Adolfo Serrano
Inventor： Michael Prencipe , Suman Chopra , Joseph Norris , Adolfo Serrano
IPC: A61K8/22
CPC classification number: A61C19/066 , A46B9/005 , A46B9/021 , A46B9/025 , A46B11/0024 , A46B11/0027 , A46B17/04 , A46B2200/10 , A46B2200/1046 , A46B2200/20 , A61C1/0092 , A61C3/005 , A61C17/0202 , A61C19/063 , A61K8/22 , A61K8/8147 , A61K2800/87 , A61K2800/92 , A61Q11/00
Abstract: The method of the present invention is directed to the storage and dispensing of a peroxide containing tooth whitening composition. During storage and subsequent use the composition in the storage chamber must be maintained segregated from the applicator surface. This is accomplished by delivering the peroxide containing tooth whitening composition from the storage chamber through a delivery channel having a length and a cross-sectional diameter sufficient to preclude the migration of moisture and the enzyme catalase from the application surface to the storage chamber. The composition is applied to teeth by means of bristles, a sponge surface or fibrillated surface. This applicator can be used with both aqueous and non-aqueous peroxide containing tooth whitening compositions.
Abstract translation: 本发明的方法涉及含过氧化物的牙齿增白组合物的储存和分配。 在储存和随后使用期间，储存室中的组合物必须保持与施用器表面分离。 这是通过将来自储存室的含过氧化物的牙齿增白组合物通过具有足以防止水分和酶过氧化氢酶从施用表面迁移到储存室的长度和横截面直径的输送通道来实现的。 组合物通过刷毛，海绵表面或原纤化表面施加到牙齿上。 该施用器可以与含水和非水过氧化物含有牙齿美白组合物一起使用。
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公开(公告)号：US20060140881A1
公开(公告)日：2006-06-29
申请号：US11301098
申请日：2005-12-12
Applicant: Guofeng Xu , Thomas Boyd , Zhigang Hao , David Viscio , Abdul Gaffar , Sarita Mello , Evangelia Arvanitidou , Michael Prencipe
Inventor： Guofeng Xu , Thomas Boyd , Zhigang Hao , David Viscio , Abdul Gaffar , Sarita Mello , Evangelia Arvanitidou , Michael Prencipe
IPC: A61K8/49
CPC classification number: A61K8/347 , A61K8/345 , A61K8/498 , A61K8/8164 , A61Q11/00
Abstract: Oral care compositions containing: a free-B-ring flavonoid and a flavan; as well as at least one bioavailability-enhancing agent are provided. Methods of using the oral compositions are also provided.
Abstract translation: 口服护理组合物，含有：B型环形黄酮和黄烷; 以及至少一种生物利用度增加剂。 还提供了使用口腔组合物的方法。
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公开(公告)号：US20060045854A1
公开(公告)日：2006-03-02
申请号：US10929087
申请日：2004-08-27
Applicant: Lynette Zaidel , Guisheng Pan , Suman Chopra , Prakasarao Mandadi , Michael Prencipe
Inventor： Lynette Zaidel , Guisheng Pan , Suman Chopra , Prakasarao Mandadi , Michael Prencipe
IPC: A61K8/22
CPC classification number: A61K8/8176 , A61K8/0208 , A61K8/22 , A61K8/24 , A61K8/49 , A61K8/817 , A61K8/891 , A61K8/90 , A61K2800/805 , A61Q11/00 , A61Q11/02
Abstract: Oral care compositions comprising: (a) a peroxide complex comprising a peroxide component and an N-vinyl heterocyclic polymer (e.g., poly-N-vinyl polylactam, or poly-N-vinyl-polyimide); (b) a whitening agent (e.g., hydrogen peroxide); and (c) an orally acceptable carrier. In one embodiment, the carrier comprises a film forming material. Methods are also provided for making an oral care composition comprising: (a) mixing a whitening agent, silicone adhesive and carrier fluid to form a homogenous mixture; (b) adding a peroxide complex to said homogenous mixture, wherein said complex comprises hydrogen peroxide and an N-vinyl heterocyclic polymer; and (c) mixing under vacuum.
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164.发明申请Tooth-whitening compositions comprising silicone polymer and methods therefor 有权包含硅氧烷聚合物的牙齿美白组合物及其方法公开(公告)号：US20050287084A1
公开(公告)日：2005-12-29
申请号：US10842154
申请日：2004-05-10
Applicant: Sayed Ibrahim , Prithwiraj Maitra , Suman Chopra , Eugene Pashkovski , Michael Prencipe
Inventor： Sayed Ibrahim , Prithwiraj Maitra , Suman Chopra , Eugene Pashkovski , Michael Prencipe
CPC classification number: A61K8/24 , A61K8/29 , A61K8/894 , A61K2800/412 , A61K2800/43 , A61Q11/00
Abstract: Tooth-imparting whiteness to fluids comprising a particulate whiteness-imparting particles such as hydroxyapatite and an organosiloxane polymer are disclosed. Methods of use of the fluids are also disclosed.
Abstract translation: 公开了赋予包含颗粒状白度赋予颗粒如羟基磷灰石和有机硅氧烷聚合物的流体的白度。 还公开了使用流体的方法。
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公开(公告)号：US20050271602A1
公开(公告)日：2005-12-08
申请号：US10859412
申请日：2004-06-02
Applicant: Nebojsa Milanovich , Thomas Boyd , Michael Prencipe
Inventor： Nebojsa Milanovich , Thomas Boyd , Michael Prencipe
Abstract: A method for inhibiting chemical staining of a dental surface comprises contacting the dental surface, prior to said staining, with an orally acceptable polymer or copolymer comprising a plurality of monomeric groups of formula (I) wherein (a) one of A and A′ is hydrogen and the other is a moiety (X)n(R)m, (b) n in individual such moieties is independently 0 or 1, (c) linking groups X if present independently comprise an oxygen, sulfur, nitrogen, phosphorus or silicon atom, (d) where n is 0, m is 1, and where n is 1, m is independently an integer from 1 to 3 as determined by X, (e) terminal groups R are independently hydrogen or C1-18 organic radicals, and (f) M and M′ are independently selected from hydrogen, alkali metal and ammonium; said polymer or copolymer having an average molecular weight of at least about 1,000.
Abstract translation: 用于抑制牙齿表面的化学染色的方法包括在所述染色之前使牙齿表面与包含多个式（I）的单体基团的口腔可接受的聚合物或共聚物接触，其中（a）A和A'之一为 氢和另一个是单独的这样的部分中的部分（X），（b）n独立地为0或1，（c）连接基团X 如果独立地包含氧，硫，氮，磷或硅原子，（d）其中n为0，m为1，并且其中n为1，m独立地为通过X确定的1至3的整数，（e ）末端基团R独立地为氢或C 1-18个有机基团，和（f）M和M'独立地选自氢，碱金属和铵; 所述聚合物或共聚物的平均分子量至少约为1,000。
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Patent Agency Ranking
公开(公告)号：US06927053B2
公开(公告)日：2005-08-09
申请号：US10229551
申请日：2002-08-28
Applicant: Malcolm Williams , Michael Prencipe , James G. Masters
Inventor： Malcolm Williams , Michael Prencipe , James G. Masters
CPC classification number: A61Q11/00 , A61K8/66 , A61K2800/88
Abstract: A two component desensitizing dentifrice composition is disclosed which comprises a first dentifrice component containing an enzyme such as papain and a second dentifrice component containing an ionic surfactant such as sodium lauryl sulfate, the first and second dentifrice components being maintained separate from the other until dispensed for application to teeth whereby enzyme activity is maintained with improved dentifrice foaming characteristics.
Abstract translation: 公开了一种双组分脱敏洁牙剂组合物，其包含含有酶如木瓜蛋白酶的第一洁齿剂组分和含有离子表面活性剂如十二烷基硫酸钠的第二洁齿剂组分，第一和第二洁齿剂组分彼此分离直到分配 应用于牙齿，由此保持酶活性并提高洁牙剂发泡特性。
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公开(公告)号：US20050069501A1
公开(公告)日：2005-03-31
申请号：US10915124
申请日：2004-08-10
Applicant: Sayed Ibrahim , Suman Chopra , Michael Prencipe
Inventor： Sayed Ibrahim , Suman Chopra , Michael Prencipe
CPC classification number: A61Q11/00 , A61K8/0208 , A61K8/24 , A61K8/8176 , A61K8/891 , A61K2800/412 , A61K2800/43
Abstract: A composition for the rapid, temporary whitening of teeth comprising an adhesive material and whitening particulates.
Abstract translation: 一种用于牙齿快速，暂时增白的组合物，其包含粘合剂材料和增白颗粒。
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公开(公告)号：US20050038181A1
公开(公告)日：2005-02-17
申请号：US10642458
申请日：2003-08-15
Applicant: Suman Chopra , Lynette Zaidel , Guisheng Pan , Suryakant Patel , Ryan Cameron , Michael Prencipe
Inventor： Suman Chopra , Lynette Zaidel , Guisheng Pan , Suryakant Patel , Ryan Cameron , Michael Prencipe
CPC classification number: A61K8/22 , A61C19/066 , A61K8/8176 , A61K8/891 , A61Q11/00
Abstract: A stable, nonaqueous liquid tooth whitening composition comprised of an anhydrous peroxide compound dispersed in an orally acceptable hydrophobic organic material such as a silicone based pressure sensitive polymer which composition when applied topically to tooth surfaces forms an adherent layer containing the peroxide compound which peroxide compound is thereafter is released from the layer to effect tooth whitening.
Abstract translation: 一种稳定的非水液体牙齿增白组合物，其由分散在口腔可接受的疏水性有机材料如硅氧烷基压敏聚合物中的无水过氧化物组合物组成，该组合物当局部施用于牙齿表面时形成含有过氧化物化合物的粘附层， 此后从该层释放以实现牙齿美白。
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公开(公告)号：US20050036956A1
公开(公告)日：2005-02-17
申请号：US10641961
申请日：2003-08-15
Applicant: Lin Fei , Suman Chopra , Prakasarao Mandadi , Neeta Patel , Ramachandra Shastry , Yelloji-Rao Mirajkar , Michael Prencipe
Inventor： Lin Fei , Suman Chopra , Prakasarao Mandadi , Neeta Patel , Ramachandra Shastry , Yelloji-Rao Mirajkar , Michael Prencipe
CPC classification number: A61K8/86 , A61K8/22 , A61K8/25 , A61K8/8135 , A61K8/8176 , A61K8/8182 , A61K8/90 , A61K2800/31 , A61Q11/00
Abstract: A stable, nonaqueous liquid tooth whitening composition comprised of an anhydrous peroxide compound dispersed in an orally acceptable mixture of an anhydrous hydrophilic polymer and an adhesion enhancer which composition when applied topically to tooth surfaces forms an adherent layer containing the peroxide compound which peroxide compound is thereafter is released from the layer to effect tooth whitening.
Abstract translation: 一种稳定的非水性液体牙齿美白组合物，其由分散在无水亲水性聚合物和粘合增强剂的口腔可接受的混合物中的无水过氧化物组合物组成，当将其局部施用于牙齿表面时，其组合物形成含有过氧化物化合物的粘附层，此后的过氧化物化合物 从层中释放以实现牙齿美白。
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公开(公告)号：US5814304A
公开(公告)日：1998-09-29
申请号：US891010
申请日：1997-07-10
Applicant: Michael Wong , Michael Prencipe , Kedar N. Rustogi
Inventor： Michael Wong , Michael Prencipe , Kedar N. Rustogi
Abstract: An aqueous abrasive whitening composition containing a peroxide whitening compound which is chemically and physically stable and exhibits heightened and rapid whitening of teeth and stain removal which comprises a combination of water, calcined alumina abrasive and a peroxide compound.
Abstract translation: 一种水性磨料增白组合物，其含有化学和物理稳定的过氧化物增白化合物，并且表现出高度和快速增白的牙齿和污迹去除，其包括水，煅烧氧化铝磨料和过氧化物化合物的组合。
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