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1.发明申请公开(公告)号：US20050069502A1
公开(公告)日：2005-03-31
申请号：US10917263
申请日：2004-08-12
申请人： Suman Chopra , Lynette Zaidel , Guisheng Pan , Suryakant Patel , Ryan Cameron , Michael Prencipe
发明人： Suman Chopra , Lynette Zaidel , Guisheng Pan , Suryakant Patel , Ryan Cameron , Michael Prencipe
IPC分类号： A61C19/06 , A61K8/20 , A61K8/22 , A61K8/38 , A61K8/81 , A61K8/89 , A61K8/891 , A61Q11/00 , A61Q11/02 , A61K7/20
CPC分类号： A61Q11/00 , A61C19/066 , A61K8/22 , A61K8/8111 , A61K8/8176 , A61K8/891
摘要： A tooth whitening system comprising a tooth whitening composition comprising a whitening agent and a hydrophobic polymer carrier. The tooth whitening composition is preferably substantially non-water soluble. The tooth whitening composition is applied to the surface of a tooth to be whitened in a mammal to effect whitening on the tooth surface. Methods of whitening a surface of a tooth are also provided.
摘要翻译： 一种牙齿美白系统，其包括含有增白剂和疏水聚合物载体的牙齿增白组合物。 牙齿美白组合物优选基本上是非水溶性的。 将牙齿美白组合物施用于哺乳动物中待白化牙齿的表面以在牙齿表面上发白。 还提供了使牙齿表面变白的方法。
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公开(公告)号：US20050038181A1
公开(公告)日：2005-02-17
申请号：US10642458
申请日：2003-08-15
申请人： Suman Chopra , Lynette Zaidel , Guisheng Pan , Suryakant Patel , Ryan Cameron , Michael Prencipe
发明人： Suman Chopra , Lynette Zaidel , Guisheng Pan , Suryakant Patel , Ryan Cameron , Michael Prencipe
CPC分类号： A61K8/22 , A61C19/066 , A61K8/8176 , A61K8/891 , A61Q11/00
摘要： A stable, nonaqueous liquid tooth whitening composition comprised of an anhydrous peroxide compound dispersed in an orally acceptable hydrophobic organic material such as a silicone based pressure sensitive polymer which composition when applied topically to tooth surfaces forms an adherent layer containing the peroxide compound which peroxide compound is thereafter is released from the layer to effect tooth whitening.
摘要翻译： 一种稳定的非水液体牙齿增白组合物，其由分散在口腔可接受的疏水性有机材料如硅氧烷基压敏聚合物中的无水过氧化物组合物组成，该组合物当局部施用于牙齿表面时形成含有过氧化物化合物的粘附层， 此后从该层释放以实现牙齿美白。
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公开(公告)号：US20060024246A1
公开(公告)日：2006-02-02
申请号：US10902720
申请日：2004-07-29
申请人： Prithwiraj Maitra , Lynette Zaidel , Suman Chopra , Guisheng Pan , Michael Prencipe , Sayed Ibrahim
发明人： Prithwiraj Maitra , Lynette Zaidel , Suman Chopra , Guisheng Pan , Michael Prencipe , Sayed Ibrahim
IPC分类号： A61K8/84
CPC分类号： A61K8/0208 , A61K8/22 , A61K8/8152 , A61K8/8176 , A61Q11/00
摘要： Oral care compositions comprising: a) an oral care active; and b) an acrylic film forming polymer. In various embodiments, such polymers comprise monomeric units such as acrylic acid, methacrylic acid, acrylates, and combinations thereof. In one embodiment, the film forming polymer comprises a copolymer of a first monomeric unit selected from the group consisting of acrylic acid, methacrylic acid, and combinations thereof, with a second monomeric unit selected from the group consisting of acrylates, acrylamindes, acetates, and combinations thereof. In various embodiments, the polymer is a terpolymer comprising a combination of the second monomeric units. Preferably, the composition additionally comprises a lower alcohol, such as ethanol. In various embodiments, the oral care active comprises a whitening material, such as a peroxide.
摘要翻译： 口腔护理组合物，其包含：a）口腔护理活性物质; 和b）丙烯酸成膜聚合物。 在各种实施方案中，这种聚合物包含单体单元，例如丙烯酸，甲基丙烯酸，丙烯酸酯及其组合。 在一个实施方案中，成膜聚合物包含选自丙烯酸，甲基丙烯酸及其组合的第一单体单元与第二单体单元的共聚物，所述第二单体单元选自丙烯酸酯，丙烯酰胺，乙酸酯和 其组合。 在各种实施方案中，聚合物是包含第二单体单元的组合的三元共聚物。 优选地，组合物另外包含低级醇，例如乙醇。 在各种实施方案中，口腔护理活性物质包含增白材料，例如过氧化物。
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公开(公告)号：US20060045854A1
公开(公告)日：2006-03-02
申请号：US10929087
申请日：2004-08-27
IPC分类号： A61K8/22
CPC分类号： A61K8/8176 , A61K8/0208 , A61K8/22 , A61K8/24 , A61K8/49 , A61K8/817 , A61K8/891 , A61K8/90 , A61K2800/805 , A61Q11/00 , A61Q11/02
摘要： Oral care compositions comprising: (a) a peroxide complex comprising a peroxide component and an N-vinyl heterocyclic polymer (e.g., poly-N-vinyl polylactam, or poly-N-vinyl-polyimide); (b) a whitening agent (e.g., hydrogen peroxide); and (c) an orally acceptable carrier. In one embodiment, the carrier comprises a film forming material. Methods are also provided for making an oral care composition comprising: (a) mixing a whitening agent, silicone adhesive and carrier fluid to form a homogenous mixture; (b) adding a peroxide complex to said homogenous mixture, wherein said complex comprises hydrogen peroxide and an N-vinyl heterocyclic polymer; and (c) mixing under vacuum.
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5.发明申请公开(公告)号：US20060147394A1
公开(公告)日：2006-07-06
申请号：US11285871
申请日：2005-11-23
申请人： Ramachandra Shastry , Yelloji Mirajkar , Nagaraj Dixit , Ryan Cameron , Qin Wang , Lynette Zaidel , Suman Chopra , Michael Prencipe
发明人： Ramachandra Shastry , Yelloji Mirajkar , Nagaraj Dixit , Ryan Cameron , Qin Wang , Lynette Zaidel , Suman Chopra , Michael Prencipe
IPC分类号： A61K8/00
CPC分类号： A61K8/22 , A61K8/8152 , A61Q11/00
摘要： In various embodiments, the present invention provides a tooth whitening composition comprising a peroxide composite and an orally acceptable carrier. The peroxide composite comprises a peroxide compound and a porous cross-linked polymer, preferably in the form of a microporous particulate. The peroxide compound can be sorbed onto the porous crosslinked polymer. The porous cross-linked polymer may comprise a polymerized polyunsaturated monomer selected from polyacrylates, polymethacrylates, polyitaconates, and mixtures thereof. The carrier can be non-aqueous, and can comprise a film forming material. Methods are also provided for whitening a tooth surface with the tooth whitening compositions.
摘要翻译： 在各种实施方案中，本发明提供了包含过氧化物复合物和口服可接受的载体的牙齿增白组合物。 过氧化物复合物包括过氧化物化合物和多孔交联聚合物，优选为微孔颗粒形式。 过氧化物可以吸附到多孔交联聚合物上。 多孔交联聚合物可以包含选自聚丙烯酸酯，聚甲基丙烯酸酯，多衣康酸酯及其混合物的聚合的多不饱和单体。 载体可以是非水的，并且可以包含成膜材料。 还提供了用于使牙齿美白组合物使牙齿美白的方法。
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公开(公告)号：US20080145321A1
公开(公告)日：2008-06-19
申请号：US12036674
申请日：2008-02-25
CPC分类号： A61K8/8176 , A61K8/0208 , A61K8/22 , A61K8/24 , A61K8/49 , A61K8/817 , A61K8/891 , A61K8/90 , A61K2800/805 , A61Q11/00 , A61Q11/02
摘要： Oral care compositions comprising: (a) a peroxide complex comprising a peroxide component and an N-vinyl heterocyclic polymer (e.g., poly-N-vinyl polylactam, or poly-N-vinyl-polyimide); (b) a whitening agent (e.g., hydrogen peroxide); and (c) an orally acceptable carrier. In one embodiment, the carrier comprises a film forming material. Methods are also provided for making an oral care composition comprising: (a) mixing a whitening agent, silicone adhesive and carrier fluid to form a homogenous mixture; (b) adding a peroxide complex to said homogenous mixture, wherein said complex comprises hydrogen peroxide and an N-vinyl heterocyclic polymer; and (c) mixing under vacuum.
摘要翻译： 口腔护理组合物，其包含：（a）包含过氧化物组分和N-乙烯基杂环聚合物（例如聚-N-乙烯基聚内酰胺或聚-N-乙烯基 - 聚酰亚胺）的过氧化物络合物; （b）增白剂（例如过氧化氢）; 和（c）口头可接受的承运人。 在一个实施方案中，载体包括成膜材料。 还提供了用于制备口腔护理组合物的方法，其包括：（a）将增白剂，硅氧烷粘合剂和载体流体混合以形成均匀的混合物; （b）向所述均匀混合物中加入过氧化物络合物，其中所述络合物包含过氧化氢和N-乙烯基杂环聚合物; 和（c）在真空下混合。
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公开(公告)号：US20080233058A1
公开(公告)日：2008-09-25
申请号：US12132359
申请日：2008-06-03
申请人： Prithwiraj Maitra , Lynette Zaidel , Suman K. Chopra , Guisheng Pan , Michael Prencipe , Syed Ibrahim
发明人： Prithwiraj Maitra , Lynette Zaidel , Suman K. Chopra , Guisheng Pan , Michael Prencipe , Syed Ibrahim
CPC分类号： A61K8/0208 , A61K8/22 , A61K8/8152 , A61K8/8176 , A61Q11/00
摘要： Oral care compositions comprising: a) an oral care active; and b) an acrylic film forming polymer. In various embodiments, such polymers comprise monomeric units such as acrylic acid, methacrylic acid, acrylates, and combinations thereof. In one embodiment, the film forming polymer comprises a copolymer of a first monomeric unit selected from the group consisting of acrylic acid, methacrylic acid, and combinations thereof, with a second monomeric unit selected from the group consisting of acrylates, acrylamides, acetates, and combinations thereof. In various embodiments, the polymer is a terpolymer comprising a combination of the second monomeric units. Preferably, the composition additionally comprises a lower alcohol, such as ethanol. In various embodiments, the oral care active comprises a whitening material, such as a peroxide.
摘要翻译： 口腔护理组合物，其包含：a）口腔护理活性物质; 和b）丙烯酸成膜聚合物。 在各种实施方案中，这种聚合物包含单体单元，例如丙烯酸，甲基丙烯酸，丙烯酸酯及其组合。 在一个实施方案中，成膜聚合物包含选自丙烯酸，甲基丙烯酸及其组合的第一单体单元与第二单体单元的共聚物，所述第二单体单元选自丙烯酸酯，丙烯酰胺，乙酸酯和 其组合。 在各种实施方案中，聚合物是包含第二单体单元的组合的三元共聚物。 优选地，组合物另外包含低级醇，例如乙醇。 在各种实施方案中，口腔护理活性物质包含增白材料，例如过氧化物。
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公开(公告)号：US09682027B2
公开(公告)日：2017-06-20
申请号：US12058424
申请日：2008-03-28
申请人： Michael Prencipe , Diane Cummins , Richard Scott Robinson , Sarita V. Mello , Richard J. Sullivan , Suman Chopra , Karen J. DePierro , Lynette Zaidel , Constantina Christopoulou , Ravi Subramanyam , Donghui Wu , Andre M. Morgan , Ralph Peter Santarpia, III , Qin Wang , Gary Edward Tambs , Rajnish Kohli , Virginia Monsul Barnes , Sergio Leite , Eric A. Simon
发明人： Michael Prencipe , Diane Cummins , Richard Scott Robinson , Sarita V. Mello , Richard J. Sullivan , Suman Chopra , Karen J. DePierro , Lynette Zaidel , Constantina Christopoulou , Ravi Subramanyam , Donghui Wu , Andre M. Morgan , Ralph Peter Santarpia, III , Qin Wang , Gary Edward Tambs , Rajnish Kohli , Virginia Monsul Barnes , Sergio Leite , Eric A. Simon
CPC分类号： A61K8/44 , A61K8/25 , A61K31/198 , A61Q11/00
摘要： This invention relates to oral care compositions comprising a basic amino acid or salt thereof, and a small particle fraction: and to methods of using and of making these compositions.
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公开(公告)号：US20090202454A1
公开(公告)日：2009-08-13
申请号：US12058209
申请日：2008-03-28
申请人： Michael Prencipe , Ravi Subramanyam , Sarita V. Mello , Donghui Wu , Suman Chopra , Andre M. Morgan , Diane Cummins , Richard J. Sullivan , Ralph Peter Santarpia, III , Lynette Zaidel , Qin Wang , Gary Edward Tambs , Virginia Monsul Barnes , Rajnish Kohli , Richard Scott Robinson , Sergio Leite , Eric A. Simon
发明人： Michael Prencipe , Ravi Subramanyam , Sarita V. Mello , Donghui Wu , Suman Chopra , Andre M. Morgan , Diane Cummins , Richard J. Sullivan , Ralph Peter Santarpia, III , Lynette Zaidel , Qin Wang , Gary Edward Tambs , Virginia Monsul Barnes , Rajnish Kohli , Richard Scott Robinson , Sergio Leite , Eric A. Simon
摘要： This invention relates to oral care compositions comprising an effective amount of a basic amino acid in free or salt form, together with an antibacterial agent, and to methods of using and of making such compositions.
摘要翻译： 本发明涉及包含游离或盐形式的有效量的碱性氨基酸与抗菌剂的口腔护理组合物，以及使用和制备这些组合物的方法。
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公开(公告)号：US10092482B2
公开(公告)日：2018-10-09
申请号：US12132359
申请日：2008-06-03
申请人： Prithwiraj Maitra , Lynette Zaidel , Suman K. Chopra , Guisheng Pan , Michael Prencipe , Sayed Ibrahim
发明人： Prithwiraj Maitra , Lynette Zaidel , Suman K. Chopra , Guisheng Pan , Michael Prencipe , Sayed Ibrahim
摘要： Oral care compositions comprising: a) an oral care active; and b) an acrylic film forming polymer. In various embodiments, such polymers comprise monomeric units such as acrylic acid, methacrylic acid, acrylates, and combinations thereof. In one embodiment, the film forming polymer comprises a copolymer of a first monomeric unit selected from the group consisting of acrylic acid, methacrylic acid, and combinations thereof, with a second monomeric unit selected from the group consisting of acrylates, acrylamides, acetates, and combinations thereof. In various embodiments, the polymer is a terpolymer comprising a combination of the second monomeric units. Preferably, the composition additionally comprises a lower alcohol, such as ethanol. In various embodiments, the oral care active comprises a whitening material, such as a peroxide.
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