公开(公告)号：US20060283585A1

公开(公告)日：2006-12-21

申请号：US11190484

申请日：2005-07-27

申请人： Paul Smith ,  Kellie Irish ,  Sam Lamancuso ,  Kevin Freestone ,  David Johnson ,  Terrence Lynch

发明人： Paul Smith ,  Kellie Irish ,  Sam Lamancuso ,  Kevin Freestone ,  David Johnson ,  Terrence Lynch

IPC分类号： F28F1/00

CPC分类号： F28F3/025 ,  F28F2225/04 ,  Y10S165/906 ,  Y10T29/49373

摘要： The present invention relates to automotive heat exchanger assemblies that can withstand high environmental temperature and pressures conditions. By providing for a tube strengthener into the tubes at the areas of highest stress, the heat exchanger assembly is strengthened to be efficient under typical operating conditions

摘要翻译： 本发明涉及能承受高环境温度和压力条件的汽车热交换器组件。 通过在最高应力的区域将管加强器提供到管中，热交换器组件被加强以在典型的操作条件下是有效的

公开(公告)号：US20060283303A1

公开(公告)日：2006-12-21

申请号：US11451537

申请日：2006-06-12

申请人： Paul Smith

发明人： Paul Smith

IPC分类号： B23D57/00

CPC分类号： B23D61/065 ,  B27G13/04 ,  B27L11/005 ,  Y10T83/9319

摘要： Adjustable blades for wood chippers and cutters include one or more blades of selected length, thickness and width, fitted with one or more bevelled blade seats in the rear blade edge, which blade seats, in a first embodiment, receive corresponding bevelled inserts having threaded openings fitted with an insert mount screw and a pair of adjusting screws. The mount screws serve to seat the inserts firmly in the blade seats and reverse-manipulation of the adjusting screws in the inserts provides adjustment of the fit of the adjustable blades in a cutting or chipping head, to compensate for re-sharpening of the blades. A method for adjusting the fit of wood cutter and chipper blades in a cutting or chipping head, which includes the steps of providing one or more bevelled insert seats in the rear edge of the blades opposite the cutting edge; placing a correspondingly-shaped bevelled insert in the insert seat or seats; threading an insert mount screw and a pair of adjusting screws through the insert; tightening the insert mount screw against the blade in the insert seat or seats and reverse-manipulating the adjusting screws to extend the adjusting screws from the insert to fit the blades in a chipping or cutting head. In a second embodiment heated babitt metal is poured into a mold receiving the adjustable blades and fills the bevelled blade seat or seats. The liquified babitt metal flows rearwardly of the blade in the mold to solidify and define a babitt extension of selected width that compensates for metal lost in the blade-sharpening operation.

摘要翻译： 用于木屑和切割器的可调节叶片包括一个或多个所选长度，厚度和宽度的叶片，其在后叶片边缘中装配有一个或多个斜切叶片座，在第一实施例中，该叶片座具有相应的倾斜插入件，其具有螺纹开口 配有插入式安装螺钉和一对调节螺钉。 安装螺钉用于将插入件牢固地安置在刀片座中，并且插入件中的调节螺钉的反向操作提供了可调节刀片在切割或切屑头中的配合的调节，以补偿刀片的再磨削。 一种用于调整切割或切屑头中切割刀和切割刀片的配合的方法，其包括以下步骤：在刀片的与刀刃相对的后缘中提供一个或多个斜切刀片座; 将相应形状的倾斜刀片放置在刀片座或座中; 穿过插入件安装螺钉和一对调节螺钉; 将插入物安装螺钉紧固在插入座或座中的刀片上，并且反向操纵调节螺钉以将调节螺钉从插入件延伸以将刀片安装在切屑或切割头中。 在第二实施例中，将加热的白垩金属倒入容纳可调叶片的模具中并填充斜切的叶片座或座。 液化的babitt金属从模具中的叶片向后流动，以固化并限定选定宽度的踩踏延伸，补偿刀片磨刀操作中的金属损失。

公开(公告)号：US20060177572A1

公开(公告)日：2006-08-10

申请号：US10506412

申请日：2003-02-28

申请人： Paul Smith ,  Peter Faguy ,  Andrew Hunt ,  Charles Quillian V ,  William Dalzell ,  Frank Witbrod ,  Stein Lee ,  William Harm ,  Yadlyne Smalley ,  Mark Batich ,  William Hoos

发明人： Paul Smith ,  Peter Faguy ,  Andrew Hunt ,  Charles Quillian V ,  William Dalzell ,  Frank Witbrod ,  Stein Lee ,  William Harm ,  Yadlyne Smalley ,  Mark Batich ,  William Hoos

IPC分类号： B05D1/12 ,  C23C16/00 ,  B05D1/02 ,  B05D1/08

CPC分类号： H01M4/8807 ,  C23C16/453 ,  H01M4/0419 ,  H01M4/8605 ,  H01M4/886 ,  H01M4/8867 ,  H01M8/04197 ,  H01M8/04291 ,  H01M8/1004

摘要： To form an ionomer-based catalytic layer on a porous substrate, a heat source (40) is used to dry an ionomer-containing spray (46) so that it does not substantially liquid flow on the substrate (14). The ionomer spray (46) may contain a catalyst. A spray (46) of mixed material for forming the catalytic layer is entrained by a gas stream and is heated and directed to a substrate surface (12). For hydrogen/oxygen fuel cells, catalytic material is incorporated into the proton-conducting membrane (56) to convert diffusing oxygen and hydrogen to water to reduce potential loss at the electrodes and maintain hydration of the proton-conducting membrane (56).

摘要翻译： 为了在多孔基材上形成基于离聚物的催化剂层，使用热源（40）干燥含离子交联聚合物的喷雾（46），使其基本上不会液体流过基板（14）。 离聚物喷雾（46）可以含有催化剂。 用于形成催化剂层的混合材料的喷雾（46）被气流夹带，并被加热并引导到基底表面（12）。 对于氢/氧燃料电池，将催化材料并入质子传导膜（56）中以将氧和氢扩散到水中以减少电极处的潜在损失并保持质子传导膜（56）的水合。

公开(公告)号：US20060098908A1

公开(公告)日：2006-05-11

申请号：US11243414

申请日：2005-10-04

申请人： Allen Clarke ,  Paul Smith

发明人： Allen Clarke ,  Paul Smith

IPC分类号： F16C23/04

CPC分类号： F16C11/0638 ,  F16C11/0614 ,  F16C23/045 ,  F16C27/063 ,  F16C2300/02

摘要： A bearing assembly comprising a housing and a ball at least partially housed within the housing. The housing comprises a race having a concave bearing surface, a sleeve surrounding the race, and a resilient member disposed between the race and the sleeve. The surfaces of the race and sleeve adjacent the resilient member and the surfaces of the resilient member preferably include at least one pair of a co-operating protrusion and recess. Alternatively, or additionally, the surfaces of the race and the sleeve adjacent the resilient member have different curvatures.

摘要翻译： 一种轴承组件，其包括壳体和至少部分地容纳在所述壳体内的球体。 壳体包括具有凹形支承表面的轮圈，围绕该座圈的套筒以及设置在座圈和套筒之间的弹性构件。 邻近弹性构件的外圈和套筒的表面以及弹性构件的表面优选地包括至少一对配合的突起和凹槽。 或者或另外，相邻于弹性构件的座圈和套筒的表面具有不同的曲率。

公开(公告)号：US07028233B2

公开(公告)日：2006-04-11

申请号：US10337076

申请日：2003-01-03

申请人： Andrew Hadley ,  Paul Smith ,  Steven Olson ,  Jeffrey Whitt

发明人： Andrew Hadley ,  Paul Smith ,  Steven Olson ,  Jeffrey Whitt

IPC分类号： G06F11/00

CPC分类号： G06F11/321 ,  G06F11/349 ,  H04L1/242

摘要： A data stream is transferred through a parallel data bus while the read or write strobe is adjusted. The resultant data is compared to the original data to detect errors with each data line of the parallel bus. The results are displayed on a grid whereby the characteristics of each line of the data bus may be visually understood. The characteristic image of the performance of the data bus may be used for debugging the bus, as well as for other uses wherein the performance is very highly characterized.

摘要翻译： 通过并行数据总线传送数据流，同时调整读取或写入选通脉冲。 将结果数据与原始数据进行比较，以检测并行总线的每个数据线的错误。 结果显示在网格上，从而可以在视觉上了解数据总线的每一行的特征。 数据总线性能的特征图像可用于调试总线，以及用于其性能非常高的特征的其他用途。

公开(公告)号：US20050194978A1

公开(公告)日：2005-09-08

申请号：US10906786

申请日：2005-03-07

申请人： Paul Smith

发明人： Paul Smith

IPC分类号： G01R31/08

CPC分类号： G01R31/083 ,  G01R31/11

摘要： A system (20) and method to locate an anomaly (22) of a conductor (24) is provided. The system (20) uses a test set (28) to inject a test signal (36) into the conductor (24) at a location (PT) and a probe (30) to detect the test signal (36) at a second location (PP). A communication link (42) between the probe (30) and the test set (28) has a predetermined propagation delay (DS), from which the system (20) can calculate a propagation delay (DTP) of the conductor (24) between the test set (28) and the probe (30), and a propagation delay (DPA) between the probe (30) and the anomaly (22). By varying the location (PP) of the probe (30) until the propagation delay (DPA) between the probe (30) and the anomaly (22) is substantially zero, the precise location (PA) of the anomaly (22) may be determined. The propagation velocity (VC) of the conductor (24) may also be determined. The physical distance (LPA) between the probe (30) and the anomaly (22), and hence the precise location (PA) of the anomaly (22), again may be determined.

摘要翻译： 提供了一种用于定位导体（24）的异常（22）的系统（20）和方法。 系统（20）使用测试装置（28）将测试信号（36）在位置（P SUB T T）和探头（30）处注入到导体（24）中以检测测试 信号（36）在第二位置（P P P P）。 探头（30）与测试装置（28）之间的通信链路（42）具有预定的传播延迟（D S S S S S），系统（20）可以从该传播延迟（D）计算传播延迟 在测试装置（28）和探头（30）之间的导体（24）的传导延迟（D＆gt; PA＆lt;＆lt; 和异常（22）。 通过改变探针（30）的位置（P SUB P P）直到探针（30）和异常（22）之间的传播延迟（D SUB PA）基本上 零，可以确定异常（22）的精确位置（P A ）。 也可以确定导体（24）的传播速度（V SUB C）。 探头（30）与异常（22）之间的物理距离（L SUB PA），因此异常（22）的精确位置（P SUB> A ）， 可以再次确定。

公开(公告)号：US20050159339A1

公开(公告)日：2005-07-21

申请号：US10957200

申请日：2004-10-01

申请人： Seetharama Acharya ,  Paul Smith ,  Belur Manjula

发明人： Seetharama Acharya ,  Paul Smith ,  Belur Manjula

IPC分类号： C07C331/28 ,  C08B15/06 ,  C08B31/00 ,  C08B37/00 ,  C08B37/02 ,  C07K14/805 ,  A61K38/42

CPC分类号： C08B31/00 ,  C07C331/28 ,  C08B15/06 ,  C08B37/0021 ,  C08B37/0039

摘要： The present invention provides pegylated hemoglobins comprising a thiocarbamoyl-phenyl-polyethylene glycol (PEG) attached to hemoglobin, and comprising a polyethylene glycol (PEG) attached to hemoglobin by an acyl group. The invention also provides methods of preparing pegylated hemoglobins using isothiocyanato phenyl carbamate of PEG and using isothiocyanato phenyl di-PEG carbamate. The invention further provides compositions and blood substitutes comprising pegylated hemoglobins and methods of treating a subject which comprise administering to the subject blood substitutes comprising non-hypertensive pegylated hemoglobins.

摘要翻译： 本发明提供了包含与血红蛋白连接的硫代氨基甲酰基 - 苯基 - 聚乙二醇（PEG）的聚乙二醇化血红蛋白，并且包含通过酰基与血红蛋白连接的聚乙二醇（PEG）。 本发明还提供使用PEG的异硫氰酸苯酯基氨基甲酸酯制备聚乙二醇化血红蛋白的方法，并使用异硫氰酸苯酯二PEG-氨基甲酸酯。 本发明进一步提供了包含聚乙二醇化血红蛋白的组合物和血液代用品以及治疗受试者的方法，其包括向所述受试者施用包含非高血压聚乙二醇化血红蛋白的血液替代物。

公开(公告)号：US20050106997A1

公开(公告)日：2005-05-19

申请号：US10983003

申请日：2004-11-05

申请人： Paul Smith

发明人： Paul Smith

IPC分类号： A41B9/00 ,  A41D13/05 ,  A41C1/00

CPC分类号： A41D13/0537 ,  A41B9/00

摘要： The present invention is a protective undergarment having an outer layer of a breathable waterproof fabric and an inner layer of a thermally insulated non-absorbent synthetic fabric. The purpose for the invention is to provide protection for skiers and others from sitting on wet, cold or snow covered surfaces. The undergarment, worn inside the outer pants of the user, is held in place by detachable elastic straps at the waist and above each knee. The undergarment only covers the user's crotch and posterior, from the waist down each leg to just above the knee.

摘要翻译： 本发明是一种保护性内衣，其具有透气防水织物的外层和绝热的非吸收性合成织物的内层。 本发明的目的是为了防止滑雪者和其他人坐在湿，冷或积雪的表面上。 穿在使用者的外裤内的内衣通过可分离的弹性带在腰部和每个膝盖上方保持就位。 内衣仅覆盖用户的裆部和后部，从腰部向下每条腿至膝盖上方。

公开(公告)号：US20050085458A1

公开(公告)日：2005-04-21

申请号：US10504109

申请日：2003-02-17

申请人： Frank Harrington ,  Paul Smith ,  Simon Ward

发明人： Frank Harrington ,  Paul Smith ,  Simon Ward

IPC分类号： A61K31/4709 ,  A61K31/496 ,  A61K31/498 ,  A61K31/538 ,  A61P25/00 ,  A61P25/22 ,  A61P25/24 ,  A61P43/00 ,  C07D401/12 ,  C07D401/14 ,  C07D413/12 ,  C07D413/14 ,  C07D498/02 ,  A61K31/58

CPC分类号： C07D401/12 ,  C07D401/14 ,  C07D413/12 ,  C07D413/14

摘要： Compounds of formula (I) and pharmaceutically acceptable salts thereof are disclosed: wherein A is optionally substituted phenyl, naphthyl, indolyl, quinolinyl, quinazolinyl, indazolyl, isoquinolinyl or benzofuranyl; b is 1, 2 or 3 and c is 1, 2 or 3, wherein b+c is 2, 3, 4 or 5; X is carbon, Y is CH, is a double bond and e is 0; or X is carbon, Y is CH2 or oxygen, is a single bond and e is 1; or X is nitrogen, Y is CH2, is a single bond and e is 0; R1 is hydrogen, cyano, halogen, C1-6alkyl, C1-6alkoxy, C1-6alkoxyC1-6alkyl, NHCOCH3 or OCONR5R6, wherein R5 and R6 are independently hydrogen or C1-6alkyl; R2 is halogen, cyano or C1-6alkoxy; d is 0, 1, 2 or 3; R3 is hydrogen, C1-6alkyl, C1-6alkanoyl, fluoroC1-6alkanoyl, C1-6alkylsulfonyl, fluoroC1-6alkylsulfonyl, carbamoyl, C1-6alkylcarbamoyl or arylC1-6alkyl; and R4, together with the nitrogen atom to which it is attached, forms an optionally substituted 5 to 7 membered heterocyclic group fused to the benzene ring, provided that when a compound of formula (I) has the following structure: wherein A, b, c, R1, e, X, Y, R2 and d are as defined above and R3 is hydrogen, C1-6alkyl or arylC1-6alkyl, then (i) X is carbon, Y is CH and is a double bond; or (ii) b and c are both 1; or (iii) the carbon atom adjacent to the oxo-substituted carbon atom in the morpholinyl ring, marked “*”, is substituted. Methods of preparing the compounds and uses of the compounds in therapy, in particular for a CNS disorder such as depression or anxiety, are also disclosed.

公开(公告)号：US20050061746A1

公开(公告)日：2005-03-24

申请号：US10979705

申请日：2004-11-02

申请人： Paul Smith ,  Timothy Badger

发明人： Paul Smith ,  Timothy Badger

IPC分类号： C02F1/50 ,  C08F12/32 ,  C02F1/42 ,  B01D15/04 ,  C07D213/18

CPC分类号： C08F8/44 ,  C02F1/50 ,  C08F12/32

摘要： A water-insoluble polymeric oxidizing medium is contemplated that has a plurality of polymerized N-pyridinium vinylbenzyl triiodide or tribromide moieties whose pyridinium rings bear two substituents, R1 and R2, that are independently a hydrido or a C1-C4 alkyl group, and correspond in structure to the formula A process for preparing aseptic water and an apparatus useful for carrying out that process, both of which utilize a contemplated polymeric oxidizing medium are disclosed, as are processes for oxidizing trivalent arsenic or antimony to pentavalent arsenic or antimony and for removing arsenic from water. Alumina particles containing meta-periodate, iron or manganese are also disclosed that can be used to sorb pentavalent arsenic and antimony, as well as cobalt and mercury.

摘要翻译： 考虑到不溶于水的聚合氧化介质，其具有多个聚合的N-吡啶鎓乙烯基苄基三碘化物或三溴化物部分，其吡啶鎓环具有两个独立地为氢或C 1 -C 4的取代基R 1和R 2 烷基，并且在结构上对应于式A制备无菌水的方法和用于实施该方法的装置，两者都利用预期的聚合物氧化介质，以及将三价砷或锑氧化成五价砷的方法 或锑，并从水中除去砷。 还公开了含有高锰酸盐，铁或锰的氧化铝颗粒，其可用于吸附五价砷和锑以及钴和汞。