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公开(公告)号：US20210172944A1
公开(公告)日：2021-06-10
申请号：US16613745
申请日：2018-05-18
Inventor： Nongjian Tao
IPC: G01N33/557 , G01N33/84
Abstract: An apparatus for label-free analysis of molecules, including interactions and reactions of the molecules, is disclosed. The apparatus is based on detecting molecule movement under the influence of an external electric field. The apparatus is able to achieve sensitive detection of molecular binding to proteins or other molecules, and conformational changes of proteins or other molecules and biochemical reactions of the proteins or other molecules. Applications of the apparatus include screening of drug molecules, kinetic analysis of posttranslational modification of proteins, and small molecule-protein interactions.
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公开(公告)号：US20210170172A1
公开(公告)日：2021-06-10
申请号：US17113638
申请日：2020-12-07
Applicant: Aymard Irakoze , Brian Lambert , Matthew Edick , J. Nathan Gross , Noel Robles , Arizona Board of Regents on Behalf of Arizona State University
Inventor： Aymard Irakoze , Brian Lambert , Matthew Edick , J. Nathan Gross , Noel Robles , Jitendran Muthuswamy
Abstract: Systems and methods for improved control and performance of cochlear implants are disclosed. In an embodiment, the audio environment is sampled, and a neural network determines suggested filter setting for the cochlear implant. The process is repeated such that, as the user moves through various audio environments having differing noise levels, satisfactory performance of the cochlear implant is maintained for the user.
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183.发明授权公开(公告)号：US11011712B2
公开(公告)日：2021-05-18
申请号：US15947092
申请日：2018-04-06
Inventor： Jian Li , Guijie Li , Zhi-Qiang Zhu
Abstract: Platinum complexes suitable for use as phosphorescent emitters or as delayed fluorescent and phosphorescent emitters having the following structure:
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184.发明申请公开(公告)号：US20210121319A1
公开(公告)日：2021-04-29
申请号：US17092855
申请日：2020-11-09
Inventor： Shengxi CHEN
IPC: A61F6/04 , A61F5/41 , B32B27/04 , C08K3/20 , B32B27/40 , A61K9/00 , A61K9/70 , A61K31/7056 , A61K33/00
Abstract: A condom apparatus including at least one of a condom containing a compound of Formula 1 wherein the condom is configured to deliver one or more active ingredients selected from the group consisting of arginine, a vasodilator, nitrates, an ergot alkaloid, a long acting alpha-adrenoceptor blocker, a short acting alpha-adrenoceptor blocker, an anti-hypertensive, a prostaglandin, and a phosphodiesterase inhibitor is disclosed.
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185.发明申请公开(公告)号：US20210111355A1
公开(公告)日：2021-04-15
申请号：US16952825
申请日：2020-11-19
Abstract: A phosphorescent emitter or delayed fluorescent and phosphorescent emitters represented by Formula I or Formula II, where M is platinum or palladium.
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Patent Agency Ranking
公开(公告)号：US20210100927A1
公开(公告)日：2021-04-08
申请号：US17065283
申请日：2020-10-07
Inventor： Kaushal Rege , Deepanjan Ghosh
IPC: A61L15/44 , A61L15/20 , A61L15/32 , A61K38/39 , A61P17/02 , A61K38/18 , A61K33/242 , A61N5/06 , A61K31/417 , A61L15/18 , A61K9/70
Abstract: A wound dressing includes: a structural material formed into a dressing; at least one immunomodulatory agent associated with the dressing; and a growth factor associated with the dressing. A wound dressing kit includes: a structural material formed into a wound dressing; an immunomodulatory agent; and a growth factor composition, wherein the structural material contains the immunomodulatory agent and/or the immunomodulatory agent is in a separate composition. A method of treating a wound in a tissue includes: applying an immunomodulatory agent to the wound; applying a wound dressing to the wound; and allowing the wound to heal with the immunomodulatory agent and wound dressing. The application of a growth factor can be before, during and/or after applying the wound dressing to the wound.
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公开(公告)号：US10969350B2
公开(公告)日：2021-04-06
申请号：US16616189
申请日：2018-05-22
Inventor： Alexandra Ros , Daihyun Kim , Austin Echelmeier , Jorvani Cruz Villarreal , Ana Egatz-Gomez , Sebastian Quintana
IPC: F16K11/02 , G01N23/20025 , B33Y80/00 , B01L3/02 , B01L3/00
Abstract: Methods and systems are provided for serial femtosecond crystallography for reducing the vast amount of waste of injected crystals practiced with traditional continuous flow injections. A micrometer-scale 3-D printed water-in-oil droplet generator device includes an oil phase inlet channel, an aqueous phase inlet channel, a droplet flow outlet channel, and two embedded non-contact electrodes. The inlet and outlet channels are connected internally at a junction. The electrodes comprise gallium metal injected within the 3-D printed device. Voltage across the electrodes generates water-in-oil droplets, determines a rate for a series of droplets, or triggers a phase shift in the droplets. An external trigger generates the droplets based on the frequency of an XFEL utilized in droplet detection, thereby synchronizing a series of droplets with x-ray pulses for efficient crystal detection. The generated droplets can be coupled to an SFX with XFEL experiment compatible with common liquid injector such as a GDVN.
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188.发明授权公开(公告)号：US10956785B2
公开(公告)日：2021-03-23
申请号：US16397990
申请日：2019-04-29
Inventor： Jianming Liang , Zongwei Zhou , Jae Shin
Abstract: Methods, systems, and media for selecting candidates for annotation for use in training classifiers are provided. In some embodiments, the method comprises: identifying, for a trained Convolutional Neural Network (CNN), a group of candidate training samples, wherein each candidate training sample includes a plurality of patches; for each patch of the plurality of patches, determining a plurality of probabilities, each probability being a probability that the patch corresponds to a label of a plurality of labels; identifying a subset of the patches in the plurality of patches; for each patch in the subset of the patches, calculating a metric that indicates a variance of the probabilities assigned to each patch; selecting a subset of the candidate training samples based on the metric; labeling candidate training samples in the subset of the candidate training samples by querying an external source; and re-training the CNN using the labeled candidate training samples.
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公开(公告)号：US20210083070A1
公开(公告)日：2021-03-18
申请号：US16573187
申请日：2019-09-17
Applicant: Massachusetts Institute of Technology , Arizona Board of Regents on behalf of Arizona State University
Inventor： Michael Geis , Joseph Varghese , Robert Nemanich
Abstract: According to some embodiments, a method for stabilizing electrical properties of a diamond semiconductor comprises terminating a surface of a diamond with hydrogen (H) or deuterium (D) atoms and over-coating the surface of the diamond with an encapsulating material comprising metal oxide salt doped with one or more elements capable of generating negative charge in the metal oxide salt.
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190.发明申请公开(公告)号：US20210076999A1
公开(公告)日：2021-03-18
申请号：US16959551
申请日：2019-01-11
Applicant: Mayo Foundation for Medical Education and Research , Arizona Board of Regents on behalf of Arizona State University
Inventor： Marylaura Thomas , Leslie Thomas , Erica Forzani
IPC: A61B5/1455 , A61B5/145 , A61B5/20 , A61B5/00 , B01D53/22 , G01N21/77 , G01N33/487
Abstract: A system with an analyzer device in fluid communication with a sample of a bodily fluid is configured to chemically or electrochemically convert at least a portion of ammonium (NH4+) contained within the bodily fluid into ammonia (NH3) and dispel the converted ammonia (NH3) into a gas sensing chamber. An ammonia (NH3) sensor located within the gas sensing chamber in conjunction with a processor can quantify an amount of ammonia (NH3) present in the gas sensing chamber in relation to the total ammonia of the bodily fluid.
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