Arrangement for cultivating cells of animal and human tissues
    13.
    发明授权
    Arrangement for cultivating cells of animal and human tissues 失效
    培养动物和人体组织细胞的布置

    公开(公告)号:US4228242A

    公开(公告)日:1980-10-14

    申请号:US934315

    申请日:1978-08-16

    IPC分类号: C12M3/04 C12M3/00

    CPC分类号: C12M27/14 C12M25/06

    摘要: An arrangement for cultivating cells of animal and human tissues in a monocellular layer and the like, has a container bounding an inner chamber for accommodating a nutrient medium, and a plurality of tubular supporting elements for supporting the cells and rotatable about an axis. The tubular rotatable elements extend in an axial direction of the inner chamber of the container. Additional elements are provided for rotating the tubular supporting elements. These additional rotating elements include an axle which defines the axis of rotation, and two end discs each arranged adjacent to and supporting one of the axial ends of the tubular supporting elements. The tubular supporting elements extend in a horizontal direction. However, they can be inclined at an angle relative to the horizontal direction by means of rotation of the end discs in mutually opposite directions.

    摘要翻译: 用于在单细胞层等中培养动物和人体组织的细胞的装置具有围绕用于容纳营养培养基的内室的容器和用于支撑细胞并围绕轴线旋转的多个管状支撑元件。 管状可旋转元件在容器的内腔的轴向方向上延伸。 提供了用于旋转管状支撑元件的附加元件。 这些附加的旋转元件包括限定旋转轴线的轴和两个端盘,每个端盘邻近并支撑管状支撑元件的轴向端之一。 管状支撑元件在水平方向上延伸。 然而,它们可以通过相互相反的方向上的端盘的旋转而相对于水平方向倾斜一定角度。

    Process for drying filtration residue
    14.
    发明授权
    Process for drying filtration residue 失效
    干燥过滤残渣的方法

    公开(公告)号:US4217700A

    公开(公告)日:1980-08-19

    申请号:US965914

    申请日:1978-12-04

    申请人: Hans Muller

    发明人: Hans Muller

    摘要: A process for drying solid residues obtained in filtration processes, in which the residue is first dried by passing a gas through it while it is still on the filter elements, and then whirl drying the residue in a lower portion of the reaction vessel. A system in which the drying gas is circulated is described. This results in a process which permits the preparation of dry filter residues which are easily transportable and avoids problems of separation from the filter elements while still wet.

    摘要翻译: 用于干燥在过滤过程中获得的固体残余物的方法,其中残留物首先通过使气体通过过滤器而被干燥,然后在反应容器的下部旋转干燥残余物。 对干燥气体循环的系统进行说明。 这导致允许制备易于运输的干燥过滤器残余物的过程,并且避免了在仍然湿润的情况下与过滤元件分离的问题。

    Device for cultivating cells of animal and human tissues
    15.
    发明授权
    Device for cultivating cells of animal and human tissues 失效
    培养动物和人体组织细胞的装置

    公开(公告)号:US4173516A

    公开(公告)日:1979-11-06

    申请号:US840165

    申请日:1977-10-06

    IPC分类号: C12M1/08 C12M3/02 C12B1/14

    CPC分类号: C12M23/34 C12M29/14

    摘要: A method of cultivating cells of animal and human tissues includes the steps of introducing the cells into a nutrient solution in which they tend to settle, and maintaining the cells in the solution in a suspended state so as to prevent their settling by introducing an oxygen-containing gas into the solution. An apparatus for carrying out the method includes a container for a nutrient solution, an arrangement for introducing the oxygen-containing gas into the container, and a guide arrangement in the container and operative for guiding the nutrient solution so that the latter performs a circulatory movement in the container when the oxygen-containing gas is introduced into the latter. The guide arrangement may be formed as a tubular member, as a substantially flat partition wall, or as an inner wall of a circumferentially complete tubular container.

    摘要翻译: 培养动物和人体组织的细胞的方法包括以下步骤:将细胞导入其倾向于沉降的营养液中,并将细胞保持在悬浮状态,以便通过引入氧 - 含有气体进入溶液。 用于实施该方法的装置包括用于营养液的容器,用于将含氧气体引入容器中的装置,以及容器中的引导装置,并用于引导营养液,使得其进行循环运动 在含氧气体被引入后者的容器中。 引导装置可以形成为管状构件,作为基本平坦的分隔壁,或形成为周向完整的管状容器的内壁。

    Process and a filter for filtering a liquid containing solids having a
substantially different specific gravity relative to the liquid
    16.
    发明授权
    Process and a filter for filtering a liquid containing solids having a substantially different specific gravity relative to the liquid 失效
    用于过滤含液体的液体的过滤和过滤器,其具有与液体相关的特别不同的特定重量

    公开(公告)号:US4152261A

    公开(公告)日:1979-05-01

    申请号:US851756

    申请日:1977-11-15

    申请人: Hans Muller

    发明人: Hans Muller

    摘要: A process is provided for filtering a liquid containing solids having a substantially different specific gravity relative to the liquid. The process includes the steps of providing a filter element having a hollow interior communicating with an outlet and being bounded by a filter mesh, passing a liquid containing solids having a substantially different specific gravity relative to the liquid against the outside of the filter mesh so that the filtrate enters into the interior and leaves the filter element through the outlet, and establishing a pressure differential between the interior and the ambient space so as to form an elevated pressure within the interior of the filter element, thereby irregular filter cake formations of the solids are at least substantially avoided because of the pressure differential between the outside of the filter mesh and the hollow interior. A filter for performing this process is also provided.

    摘要翻译: 提供了一种用于过滤含有相对于液体具有基本上不同比重的固体的液体的方法。 该方法包括提供具有中空内部的过滤元件的步骤,该中空内部与出口连通并且被过滤网限定,使含有相对于液体的比重基本上不同的固体的液体抵靠过滤网的外部通过,使得 滤液进入内部并通过出口离开过滤元件,并在内部和环境空间之间建立压差,以在过滤元件的内部形成升高的压力,由此固体的不规则滤饼形成 由于滤网的外部和中空的内部之间的压力差异至少基本上避免了。 还提供了用于执行该过程的过滤器。

    Disc filter having means for sensing the thickness of filter cakes and
method of filtering with the filter
    17.
    发明授权
    Disc filter having means for sensing the thickness of filter cakes and method of filtering with the filter 失效
    盘式过滤器具有用于感测过滤器蛋糕的厚度的装置和用过滤器过滤的方法

    公开(公告)号:US4070288A

    公开(公告)日:1978-01-24

    申请号:US675189

    申请日:1976-04-08

    申请人: Paul Gerteis

    发明人: Paul Gerteis

    摘要: A disc filter includes a housing and a plurality of filter discs mounted in the housing at different levels of the latter. Means is provided for sensing the presence of a filter cake formed on one of the filter discs when the filter cake has a predetermined thickness. The sensing means includes a sensing member which is displaceable in response to the generation of a pressure differential thereacross. The sensing means further includes a switch which is connected with the sensing member and is operative in response to displacement of the sensing member. The sensing member, which is favorably in the form of a plate, is located intermediate a pair of the filter discs and is preferably arranged immediately below the lower surface of the upper filter disc of the pair. In operation, a medium to be filtered is admitted into the housing of the filter under pressure. As the medium is filtered by the filter discs, filter cakes build up on the filter discs. When the filter cake formed on the filter disc located immediately below the sensing member reaches the level of the sensing member, a pressure differential caused by the pressure of the medium being filtered is created across the sensing member. As a result, the sensing member is displaced and a signal is generated. The signal may be used to terminate the filtering operation so that the thicknesses of the filter cakes do not become excessive.

    摘要翻译: 盘式过滤器包括壳体和安装在壳体中的不同级别的多个过滤盘。 提供了用于在滤饼具有预定厚度时感测在一个滤盘上形成的滤饼的存在的装置。 感测装置包括感测构件,该感测构件可响应于其间的压力差的产生而移位。 感测装置还包括开关,该开关与感测构件连接并响应感测构件的位移而起作用。 有利地为板形式的感测构件位于一对过滤盘之间,并且优选地布置在该对的上过滤盘的下表面的正下方。 在操作中,要过滤的介质在压力下进入过滤器的壳体。 当介质由滤盘过滤时,过滤器滤饼会积聚在滤芯上。 当形成在位于感测构件正下方的过滤盘上的滤饼达到感测构件的高度时,跨过感测构件产生由被过滤的介质的压力引起的压力差。 结果,检测构件发生位移并产生信号。 该信号可以用于终止过滤操作,使得过滤蛋糕的厚度不会变得过大。

    Method and device for separating liquid and/or gas from liquid or
gaseous mixture
    18.
    发明授权
    Method and device for separating liquid and/or gas from liquid or gaseous mixture 失效
    从液体或气体混合物中分离液体和/或气体的方法和装置

    公开(公告)号:US4828719A

    公开(公告)日:1989-05-09

    申请号:US63254

    申请日:1987-06-17

    摘要: In a method and a device for extracting liquid or gas from a liquid or gaseous mixture containing dispersed solid particles, a cylindrical filter disposed in a container receiving a mixture to be filtered is subjected to oscillations in the axial direction of the filter while the mesh of the filter is of the size greater than that of particles to be retained on the filter.

    摘要翻译: 在用于从含有分散的固体颗粒的液体或气体混合物中提取液体或气体的方法和装置中,设置在容纳待过滤混合物的容器中的圆筒形过滤器在过滤器的轴向方向上受到振动, 过滤器的尺寸大于要保留在过滤器上的颗粒的尺寸。

    Method and apparatus for the submerged growth of cell cultures
    19.
    发明授权
    Method and apparatus for the submerged growth of cell cultures 失效
    细胞培养物浸没生长的方法和装置

    公开(公告)号:US4749654A

    公开(公告)日:1988-06-07

    申请号:US321893

    申请日:1981-11-16

    摘要: In a method and apparatus for the submersed growth of human and animal cell cultures, the cell growth container is provided with a centrally disposed permeator, which is formed simultaneously as conduit tube and reactor, and is provided on both sides with gas-permeable membranes. A gas of defined composition is led through the hollow porous support body of the permeator as fresh gas on one side, and led away on the other side as waste gas. In this manner the gas delivers oxygen across the membrane and receives carbon dioxide. The nutrient substrate and the tissue cells are held in suspension by means of a stirrer provided in the interior of the permeator. Foam problems do not occur, since no gas bubbles can enter into the medium.

    摘要翻译: 在用于人和动物细胞培养物浸没生长的方法和装置中,细胞生长容器设置有中心设置的渗透器,其同时形成为导管和反应器,并且在两侧设置有透气膜。 定义成分的气体作为一侧的新鲜气体引导通过渗透器的中空多孔支撑体,并在另一侧作为废气引出。 以这种方式,气体将氧气输送到膜上并接收二氧化碳。 营养基质和组织细胞通过设置在渗透器内部的搅拌器保持在悬浮液中。 泡沫问题不会发生,因为没有气泡可以进入介质。

    Method and fermenter for growing tissue cells
    20.
    发明授权
    Method and fermenter for growing tissue cells 失效
    用于生长组织细胞的方法和发酵罐

    公开(公告)号:US4725548A

    公开(公告)日:1988-02-16

    申请号:US860689

    申请日:1986-05-02

    申请人: Daniel Karrer

    发明人: Daniel Karrer

    CPC分类号: C12M29/04 C12M33/14

    摘要: In submerged growing of tissue cells on microcarriers in a culture medium, the culture medium is alternately aerated or withdrawn from a bottom of a culture container via a sintered plate. An air chamber is formed under the sintered plate.

    摘要翻译: 在培养基中的微载体上的组织细胞的浸没生长中,培养基通过烧结板从培养容器的底部交替充气或取出。 在烧结板下方形成有气室。