PERITONEAL DIALYSIS SYSTEM HAVING A PATIENT LINE FILTER

    公开(公告)号:US20250018100A1

    公开(公告)日:2025-01-16

    申请号:US18710712

    申请日:2022-11-18

    Abstract: A peritoneal dialysis (“PD”) system (10) includes a PD machine (20); a patient line (50) extending from the PD machine (20); and a filter set (100) in fluid communication with the patient line (50), the filter set (100) including a filter membrane (120, such as a sterilizing grade or a bacteria reduction filter membrane) positioned and arranged such that fresh PD fluid flows through the filter membrane (120) into a filtered fluid compartment (106f), wherein the filtered fluid compartment (106f) includes an outlet (106t) to a port (106p), and wherein the port (106p) is in fluid communication with a used PD fluid tube (106u) positioned and arranged to carry used PD fluid past the filter membrane (120) without contacting the filter membrane (120). A method for priming filter set (100) is also disclosed.

    Multi-chamber bag for parenteral nutrition solutions

    公开(公告)号:US12186266B2

    公开(公告)日:2025-01-07

    申请号:US17543933

    申请日:2021-12-07

    Abstract: A flexible multi-chamber bag for storing and reconstituting parenteral nutrition solutions is disclosed. The flexible multi-chamber bag comprises a first peelably sealing wall and a second peelably sealing wall between the two polymer films extending from the top edge to the bottom edge and separating the first bag into a first chamber between the first peelably sealing wall and the second peelably sealing wall, a first space between the left edge and the first peelably sealing wall, a second space between the second peelably sealing wall and the right edge; a third peelably sealing wall extending from the left edge to the first peelably sealing wall to separate the first space to form a third chamber and a fourth chamber; and a fourth peelably sealing wall extending from the right edge to the second peelably sealing wall to separate the second space to form a second chamber and a fifth chamber.

    PRIMING SENSOR FOR A MEDICAL FLUID DELIVERY SYSTEM

    公开(公告)号:US20240399040A1

    公开(公告)日:2024-12-05

    申请号:US18800704

    申请日:2024-08-12

    Inventor: John Zafiris

    Abstract: A priming sensor for a medical fluid delivery device is disclosed. In an example, the priming sensor includes light emitters and a detector. The detector is configured to detect light emitted by the emitters that interacts with a patient tube connected to the priming sensor. A processor of a medical fluid delivery device causes the emitters to operate in a sweep pattern during a sweep period. The processor receives output data from the detector that is indicative of light detected during the sweep period. The processor creates an output waveform corresponding to the sweep period based on the output data and compares the output waveform to at least one reference waveform to determine one of (a) a no-tube state, (b) a dry tube state, or (c) a wet tube state. The processor provides an output indicative of the comparison for operation of the medical fluid delivery device.

    SYSTEM AND METHOD FOR GENERATING BATTERY ALARMS IN INFUSION DEVICES

    公开(公告)号:US20240374821A1

    公开(公告)日:2024-11-14

    申请号:US18779744

    申请日:2024-07-22

    Abstract: A system and method are disclosed for detecting remaining battery voltage or capacity in an infusion device and generating alarms based on the detection. A battery lifetime extension method includes providing an infusion device that derives its power from a rechargeable battery. The infusion device may derive its power from a rechargeable battery. Furthermore, the infusion device receives, at predetermined intervals of time in real-time sensor data comprising a voltage, a change in the voltage over the predetermined interval of time, an average current, a temperature, and a remaining voltage or capacity reported by a battery gas gauge integrated circuit (“IC”) associated with the rechargeable battery. A customized neural network model utilizes the sensor data to determine an indicia of the actual remaining voltage or capacity of the rechargeable battery in real-time. The indicia may be used to lengthen and/or abate ongoing medical infusion therapy.

    Daptomycin formulations containing a combination of sorbitol and mannitol

    公开(公告)号:US12128085B2

    公开(公告)日:2024-10-29

    申请号:US17487734

    申请日:2021-09-28

    CPC classification number: A61K38/12 A61K9/0019 A61K9/08 A61K47/02 A61K47/26

    Abstract: In an aspect, a method of manufacture of a pharmaceutically acceptable solid composition containing daptomycin includes drying an aqueous solution containing (i) water, (ii) the daptomycin, (iii) sorbitol in an amount of about 1.2 wt. % to about 9.0 wt. % of total volume of the aqueous composition and (iv) mannitol in an amount of about 0.6 wt. % to about 9.5 wt. % of total volume of the aqueous composition to form the solid composition. The drying can include an sublimation drying of about −25° C. to about 50° C. for a time period of about 15 hours to about 120 hours, most preferably about 15° C. for about 20 hours, optionally preceded and/or followed by one or more additional drying steps. Other aspects are the solid composition containing the daptomycin and also methods of treating a bacterial infection including administering a pharmaceutically acceptable product made by reconstituting the solid composition.

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