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11.Cerebral Intraventricular Transplantation as Method of Treating Amyotrophic Lateral Sclerosis (ALS) 有权
标题翻译: 脑室内移植作为治疗肌萎缩性侧索硬化症(ALS)的方法公开(公告)号:US20050249708A1
公开(公告)日:2005-11-10
申请号:US10908322
申请日:2005-05-06
申请人: Svitlana Garbuzova-Davis , Andrew Balber , Cyndy Davis-Sanberg , Tracy Gentry , Nicole Kuzmin-Nichols , Paul Sanberg , Alison Willing
发明人: Svitlana Garbuzova-Davis , Andrew Balber , Cyndy Davis-Sanberg , Tracy Gentry , Nicole Kuzmin-Nichols , Paul Sanberg , Alison Willing
IPC分类号: A61K31/203 , A61K35/12 , A61K35/14 , A61K35/28 , A61K35/51 , A61K45/00 , A61K45/06 , C12N5/074 , C12N5/0789 , C12N5/08
CPC分类号: A61K35/28 , A61K9/0085 , A61K31/203 , A61K35/30 , A61K35/50 , A61K35/51 , A61K45/06 , A61K2035/124 , C12N5/0607 , C12N5/0647 , C12N5/0662 , C12N5/0663 , C12N5/0664 , C12N5/0665 , C12N5/0666 , C12N5/0667 , C12N5/0668 , C12N2501/13 , C12N2501/385 , C12N2506/11 , A61K2300/00
摘要: A method of treating a patient with a neurodegenerative disease, such as ALS, using progenitor cells isolated from human umbilical cord blood. Non-invasive transplantation of aldehyde dehydrogenase (ALDH+) expressing progenitor cells provides cell replacement and protection of motor neurons.
摘要翻译: 使用从人脐带血分离的祖细胞来治疗患有神经变性疾病的患者(例如ALS)的方法。 表达祖细胞的醛脱氢酶(ALDH + +)表达的非侵入性移植提供了运动神经元的细胞替代和保护。