摘要:
Disclosed are a series of α-amino-N-substituted amide compounds having a structure of the following formula, the pharmaceutically acceptable salts thereof, and the pharmaceutical composition comprising the same. The α-amino-N-substituted amide compounds or the pharmaceutically acceptable salts thereof according to the present invention have anti-tumor and/or anti-cancer activities in vivo and in vitro, can effectively depress the growth of various tumor cells and/or cancer cells, and thus can be used in preparing drugs for treating tumors and/or cancers.
摘要:
Provided herein are compounds for treatment of KIT, CSF-1R and/or FLT3 kinase mediated diseases. Also provided are pharmaceutical compositions comprising the compounds and methods of using the compounds and compositions.
摘要:
A battery charging apparatus for an electric vehicle (EV) or a hybrid electric vehicle (HEV) includes a case chassis, a circuit board and at least one electronic component. The case chassis includes a plurality of side plates, a bottom plate and a receptacle. The circuit board is accommodated within the receptacle of the case chassis. The electronic component includes a passive component body with a plurality of conductive wires and a fixing member for accommodating the passive component body. The conductive wires are electrically connected to the circuit board. The fixing member is fixed on at least one of the side plates and the bottom plate of the case chassis.
摘要:
The invention relates to compositions and methods of treatment using an iron chelator, an antioxidant, estrogen, and/or combinations thereof, optionally, linked to a nanoparticle, to treat a subject in need thereof. The compositions and methods may be used to restore or protect the normal functions of osteoblast and osteoclast by depleting iron and inhibiting oxidative damage. The compositions and methods may also be used to increase the bone formation rate in a subject.
摘要:
Detecting data errors in connection with a data transfer process includes performing an XOR operation on a plurality of data blocks to obtain a data block XOR result. An XOR operation may be performed on a plurality of cyclic redundancy check (CRC) codes associated with the plurality of data blocks to obtain a CRC XOR result. The data block XOR result and the CRC XOR result may be used to determine whether an error exists in the plurality of data blocks. The system may be used in connection with local IO transfers and in connection with local CPU XOR operations for a RAID system in which data may be mirrored, striped or otherwise distributed across multiple storage devices.
摘要:
A multi-function clamp for veterinarian, mainly includes upper clip and lower clip; the clamp body is composed by upper clip, lower clip, bolt and torsional spring, wherein the foresaid clamp body installed with connection assembly that has connecting lead wires, and the connection assembly has several installation sections coordinates with the lead wire plug. By adopting the compatibility design, the multi-function clamp for veterinarian could apply to wider areas, a pet clinic equipped with the multi-function clamp for veterinarian is applicable even using the probe-type lead wires, the banana plug lead wires, the snap-type lead wires and the clip-type lead wires simultaneously, which greatly decreases the procurement cost for equipment and accessories, and easier to be operated. Furthermore, by adopting the anti-slip design, the multi-function clamp for veterinarian will improve remarkably for the matter the clamp drops off from the operators or the animal skins, which saves time in operation.
摘要:
A computer bezel includes a main body, a door secured to the main body, a pushing member slidably secured to the main body, and a driving member rotatably secured to the main body. The main body defines a through opening. The door is rotated between a closed position, where the door covers the through opening, and an open position, where the door is rotated away from the main body to expose the through opening. The pushing member is slid between a first position, where the pushing member is disengaged from the driving member, and a second position, where the pushing member rotates the driving member. When the driving member is slid from the first position to the second position, the driving member is capable of sliding a tray of a disk drive out of the disk drive, and the door will rotate from the closed position to the open position.
摘要:
A button device includes a button unit, a resilient member, and a switch unit. The button unit includes a button, a transparent power icon member, and a retaining member. The power iron member is attached to the button. The retaining member includes an elastic element, a tray located at one end of the elastic element, and a fixing loop located at the other end of the elastic element. The button and the power iron member are retained on the tray. The tray includes a seat with a hole for receiving an illuminator, and reflects lights of the illuminator to the power icon member. The resilient member is sandwiched between the button unit and the switch unit to reset the button unit back to its original position.
摘要:
A method is provided for carrying out multi-step separations of objects bearing at least two binding sites. In the first step, a first binder/bead composition is bound to objects that bear the first binding site, and then unbound objects, i.e. objects not bearing the first binding site, are separated from bound objects. In the second step, a second binder/bead composition is bound to the remaining objects that bear the second binding site, and then the objects that are bound to both beads are removed from those objects that are bound to only one bead. The beads can differ in magnetic responsiveness, charge, size, color, and the like, and these differences can be used to carry out the separation steps.
摘要:
A method for copying data from a source hard drive to a target hard drive is implemented in an electronic device. The source hard drive stores a master boot record (MBR) recording a SYSTEM partition and at least one other partition. The electronic device copies information related to the SYSTEM partition to a file to store in the source hard drive and modifies the MBR to be a modified MBR by erasing the SYSTEM partition. The electronic device then creates a diagnostic sub-partition for system diagnostics in one of the at least one other partition, copies the file to the diagnostic sub-partition, and copies the modified MBR in the target hard drive. When the system diagnostics is implemented for the target hard drive, the electronic device restores the SYSTEM partition in the target hard drive based on the file.