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公开(公告)号:US20180200157A1
公开(公告)日:2018-07-19
申请号:US15744768
申请日:2016-07-13
Applicant: JUVIC INC.
Inventor: Hyung Il JUNG , Hui Suk YANG
CPC classification number: A61K8/0204 , A61K8/498 , A61K8/676 , A61K8/735 , A61K9/0021 , A61Q19/02 , B81B1/008 , B81B2201/055 , B81C1/00111
Abstract: The present invention relates to a method of manufacturing a microstructure, including: (a) forming a solid on a substrate; (b) fluidizing the solid by adding a solvent thereto; and (c) shaping the fluidized solid, and a microstructure manufactured using the method.
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12.
公开(公告)号:US20230414746A1
公开(公告)日:2023-12-28
申请号:US18087745
申请日:2022-12-22
Inventor: Hyungil JUNG , Huisuk YANG , Geonwoo KANG
IPC: A61K39/145 , A61M37/00 , A61K9/00 , A61P31/16
CPC classification number: A61K39/145 , A61M37/0015 , A61K9/0021 , C12N2760/16134 , A61M2037/0046 , A61M2037/0061 , A61P31/16
Abstract: The present invention relates to a microneedle including an influenza vaccine and particularly a soluble microneedle including an influenza vaccine, and more specifically to a microneedle including an influenza vaccine and an influenza vaccine patch including the same that can increase the stability of the influenza vaccine and expect a higher immune effect by including a water-soluble polymer and an additive at a specific ratio, and when the microneedle including the influenza vaccine of the present invention is used, not only the stability of the vaccine is increased, but also the skin penetration and drug delivery effect are remarkably excellent.
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公开(公告)号:US20220347451A1
公开(公告)日:2022-11-03
申请号:US17864542
申请日:2022-07-14
Inventor: Hyung Il JUNG , Hui Suk YANG , Hyeon Jun KIM
IPC: A61M37/00
Abstract: A microneedle applicator is provided. A microneedle applicator according to an embodiment of the present invention comprises: a microneedle array; an operation member disposed on the upper portion of the microneedle array and operating such that a user applies an external force so as to insert a microneedle into skin; a housing for accommodating the microneedle array and the operation member; a first guide member disposed in at least one position on a lateral portion of the operation member or on a lateral portion of an interworking member of the operation member; and a second guide member which is disposed on the inner surface of the housing in a position corresponding to the first guide member so as to be engaged with the first guide member, and allows the first guide member to slide so as to prevent the microneedle array from rotating or horizontally distorting when the microneedle array uniformly vertically descends due to the external force.
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公开(公告)号:US20190209822A1
公开(公告)日:2019-07-11
申请号:US16300531
申请日:2017-05-10
Applicant: JUVIC INC.
Inventor: Hyung IL JUNG , Chengguo LI , Yonghao MA
CPC classification number: A61M37/0015 , A61M37/00 , A61M2037/0023 , A61M2037/0053 , B81C1/00 , C25D3/02 , C25D3/12 , C25D5/54 , C25D5/56
Abstract: The present invention relates to a microstructure and a manufacturing method therefor, the method comprising the steps of: (a) forming a water-soluble microstructure core on a substrate; and (b) forming a waterproof thin film on the water-soluble microstructure core.
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公开(公告)号:US20180133448A1
公开(公告)日:2018-05-17
申请号:US15815954
申请日:2017-11-17
Applicant: JUVIC INC.
Inventor: Hyung Il JUNG , Hui Suk YANG
CPC classification number: A61M37/0015 , A61K9/0021 , A61K9/0097 , A61K9/08 , A61K9/703 , A61K47/36 , A61M2037/0046 , A61M2037/0053 , A61M2037/0061 , B29C41/12 , B29C41/36 , B29L2031/7544 , B29L2031/756
Abstract: Disclosed are a microstructure-based drug delivery system comprising a microporous structure and a method for manufacturing the same, and more specifically, a detachable microstructure-based drug delivery system using a microporous structure layer and a method for manufacturing the same, thereby skipping a drying step which is essential for the manufacturing process of the existing biodegradable microneedle, and solving the problem in that the hardness of the microneedle is reduced when the microneedle contains drugs, failing to penetrate the skin. Here, the microstructure is implantable in the body through the insertion into the body and detachment from the microporous structure, and the detachable microstructure can be applied to wrinkled (skin movement) and corrugated parts through a detachment function thereof.
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公开(公告)号:US09943674B2
公开(公告)日:2018-04-17
申请号:US14622716
申请日:2015-02-13
Applicant: JUVIC INC.
Inventor: Hyung Il Jung , Hui Suk Yang
CPC classification number: A61M37/0015 , A61K9/0021 , A61K9/0097 , A61K9/08 , A61K9/703 , A61K47/36 , A61M2037/0046 , A61M2037/0053 , A61M2037/0061 , B29C41/12 , B29C41/36 , B29L2031/7544 , B29L2031/756
Abstract: Disclosed are a microstructure-based drug delivery system comprising a microporous structure and a method for manufacturing the same, and more specifically, a detachable microstructure-based drug delivery system using a microporous structure layer and a method for manufacturing the same, thereby skipping a drying step which is essential for the manufacturing process of the existing biodegradable microneedle, and solving the problem in that the hardness of the microneedle is reduced when the microneedle contains drugs, failing to penetrate the skin. Here, the microstructure is implantable in the body through the insertion into the body and detachment from the microporous structure, and the detachable microstructure can be applied to wrinkled (skin movement) and corrugated parts through a detachment function thereof.
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公开(公告)号:US12233229B2
公开(公告)日:2025-02-25
申请号:US17183056
申请日:2021-02-23
Inventor: Hyung Il Jung , Hui Suk Yang , Hyeon Jun Kim
IPC: A61M37/00
Abstract: The present invention relates to a perforated plate microstructure module, and more particularly, to a perforated plate microstructure module which can be used to deliver a drug into the skin.
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公开(公告)号:US20210393933A1
公开(公告)日:2021-12-23
申请号:US17283492
申请日:2019-09-27
Inventor: Hyungil JUNG , Geonwoo KANG , Huisuk YANG
IPC: A61M37/00
Abstract: A microstructure is provided. A microstructure according to an embodiment of the present invention comprises: a tip portion formed on a substrate and comprising a drug; and a separation portion which is formed between the substrate and the tip portion and, after the tip portion has been inserted into the skin, separates the substrate and the tip portion physically by means of an external force or chemically by means of a chemical material.
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公开(公告)号:US11104044B2
公开(公告)日:2021-08-31
申请号:US16093587
申请日:2017-04-12
Applicant: JUVIC INC.
Inventor: Hyung Il Jung , Hui Suk Yang
Abstract: Provided is a rotating assembly. The rotating assembly is for forming a microstructure, and comprises: a rotating body rotatable about a rotary shaft; a first support member installed on the rotating body so as to be spaced apart from the rotational shaft and having a predetermined viscous composition disposed on an outer surface thereof; and a fluid communicating portion for communicating the inside and the outside of the rotating body, wherein when the rotating body rotates, the viscous composition is pulled in a radially outward direction of the rotary shaft, and the pulled viscous composition is cured through the fluid communicating portion, thereby forming a microstructure.
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公开(公告)号:US20200230846A1
公开(公告)日:2020-07-23
申请号:US16093587
申请日:2016-04-12
Applicant: JUVIC INC.
Inventor: Hyung Il JUNG , Hui Suk YANG
Abstract: Provided is a rotating assembly. The rotating assembly is for forming a microstructure, and comprises: a rotating body rotatable about a rotary shaft; a first support member installed on the rotating body so as to be spaced apart from the rotational shaft and having a predetermined viscous composition disposed on an outer surface thereof; and a fluid communicating portion for communicating the inside and the outside of the rotating body, wherein when the rotating body rotates, the viscous composition is pulled in a radially outward direction of the rotary shaft, and the pulled viscous composition is cured through the fluid communicating portion, thereby forming a microstructure.
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