公开(公告)号：US20080228261A1

公开(公告)日：2008-09-18

申请号：US11724089

申请日：2007-03-13

Applicant: Boris Anukhin ,  Hao-Ming Hsiao ,  Keif Fitzgerald

Inventor： Boris Anukhin ,  Hao-Ming Hsiao ,  Keif Fitzgerald

IPC: A61F2/06

CPC classification number: A61F2/915 ,  A61F2002/91541 ,  A61F2002/91583 ,  A61F2230/0054 ,  A61F2250/0036

Abstract: An expandable stent is implanted in a body lumen, such as a coronary artery, peripheral artery, or other body lumen. The stent includes a plurality of rings connected by links. The stent has a high degree of flexibility in the longitudinal direction, yet has adequate vessel wall coverage and radial strength sufficient to hold open an artery or other body lumen. The stent can be compressed or crimped onto a catheter to a very low profile since links are integrally formed from a portion of the struts forming the rings. The stent is constructed so that the cylindrical rings are very close together in order to provide maximum scaffolding, and if the stent has a drug coating, to provide a uniform drug delivery over the length of the stent. The connecting links are integrally formed from a portion of the struts forming the rings so that the links can have a maximum length thereby providing increased longitudinal flexibility of the stent.

Abstract translation: 可扩张支架植入体腔，例如冠状动脉，外周动脉或其他体腔。 支架包括通过连杆连接的多个环。 支架在纵向具有高度的柔性，但具有足够的容器壁覆盖和径向强度足以保持打开动脉或其他体腔。 支架可以被压缩或卷曲到导管上以非常低的轮廓，因为连杆由形成环的支柱的一部分整体形成。 支架被构造成使得圆柱形环非常靠近在一起以便提供最大的脚手架，并且如果支架具有药物涂层，以在支架的长度上提供均匀的药物递送。 连接连杆由形成环的支柱的一部分整体形成，使得连杆可以具有最大长度，从而提供支架的增加的纵向柔性。

公开(公告)号：US20050060025A1

公开(公告)日：2005-03-17

申请号：US10661361

申请日：2003-09-12

Applicant: David Mackiewicz ,  Keif Fitzgerald ,  Boris Anukhin

Inventor： David Mackiewicz ,  Keif Fitzgerald ,  Boris Anukhin

IPC: A61F2/00 ,  A61F2/06 ,  A61F2/90

CPC classification number: A61F2/915 ,  A61F2/91 ,  A61F2002/91533 ,  A61F2002/91575 ,  A61F2002/91591 ,  A61F2250/0098

Abstract: An implantable medical device includes a structural body made from a superelastic material and includes one or more marker holders integrally formed on the structural body. Each marker holder is designed to hold a radiopaque marker which has a level of radiopacity greater than the superelastic material. The radiopaque marker can be made from a nickel-titanium alloy which includes a ternary element. The ternary element can be selected from the group of elements consisting of iridium, platinum, gold, rhenium, tungsten, palladium, rhodium, tantalum, silver, ruthenium, and hafnium. In one form, the marker holder includes a pair of projecting fingers connected together at a notched region to cooperatively create a particular-shaped opening. This opening, in turn, is adapted to receive a similarly shaped portion formed on the radiopaque marker. In one form, the radiopaque marker includes an inner core which is partially, or completely, encased by an outer layer. This inner core can be made from a highly radiopaque material while the outer layer is formed from a material that is easier to weld to the marker.

Abstract translation: 可植入医疗装置包括由超弹性材料制成的结构体，并且包括一体地形成在结构体上的一个或多个标记支架。 每个标记支架被设计成夹持不透射线材料的不透射线水平的不透射线的标记。 不透射线的标记可以由包括三元元素的镍 - 钛合金制成。 三元元素可以选自铱，铂，金，铼，钨，钯，铑，钽，银，钌和铪组成的元素组。 在一种形式中，标记器夹持器包括在凹口区域处连接在一起的一对突出指状物，以协作地形成特定形状的开口。 该开口又适于接收形成在不透射线标记上的类似形状的部分。 在一种形式中，不透射线标记包括部分地或完全被外层包围的内芯。 该内芯可以由高度不透射线的材料制成，而外层由易于焊接到标记的材料形成。

公开(公告)号：US20120296410A1

公开(公告)日：2012-11-22

申请号：US13557303

申请日：2012-07-25

Applicant: Hao-Ming HSIAO ,  Keif FITZGERALD ,  Boris ANUKHIN

Inventor： Hao-Ming HSIAO ,  Keif FITZGERALD ,  Boris ANUKHIN

IPC: A61F2/84

CPC classification number: A61F2/06 ,  A61F2/91 ,  A61F2/915 ,  A61F2002/91558 ,  A61F2002/91575 ,  A61F2230/0013

Abstract: System including a delivery catheter and a stent disposed at a distal end of the delivery catheter. The stent includes a plurality of radially expandable rings disposed adjacent to one another to define a tubular member having a proximal end portion, and a distal end portion, and a middle portion, each of the radially expandable rings including a plurality of strut members. The middle portion of the tubular member include a plurality of interconnection members extending between longitudinally adjacent expandable rings, the number of the plurality of the interconnection members being greater than that of the end portion of the tubular member. The stent also includes a transition section between the end portion and the middle portion, the transition section including at least one open cell and at least one closed cell. The stent can be self-expandable or balloon expandable.

Abstract translation: 包括输送导管和设置在输送导管远端的支架的系统。 所述支架包括彼此相邻设置的多个可径向扩张的环，以限定具有近端部分的管状构件，以及远端部分和中间部分，每个所述径向可扩张环包括多个支柱构件。 管状构件的中间部分包括在纵向相邻的可膨胀环之间延伸的多个互连构件，多个互连构件的数量大于管状构件的端部的数量。 支架还包括在端部和中间部分之间的过渡部分，过渡部分包括至少一个开放电池和至少一个闭合电池。 支架可以是自扩张的或气囊扩张的。

公开(公告)号：US08257420B2

公开(公告)日：2012-09-04

申请号：US12271053

申请日：2008-11-14

Applicant: Keif Fitzgerald ,  Leticia Castillon

Inventor： Keif Fitzgerald ,  Leticia Castillon

IPC: A61F2/06

CPC classification number: A61F2/95 ,  A61F2002/9665

Abstract: A stent delivery catheter system having a reinforcing tether member secured to the catheter such that the catheter is provided with an improved combination of an enhanced tensile strength together with other catheter performance characteristics such as low profile and high flexibility. The stent delivery system includes an elongated delivery catheter including a reinforcing tether member secured to the inner tubular member of the catheter. The tether member has a distal end length extending helically from the distal tip member or proximally adjacent to the proximal end of the distal tip member of the catheter and a portion that also extends axially through the stent holder region of the catheter. This reinforcing tether member provides enhanced tensile strength to the catheter.

Abstract translation: 一种支架输送导管系统，其具有固定到导管的加强系绳构件，使得导管具有增强的拉伸强度与其它导管性能特征（例如低轮廓和高柔性）的改进组合。 支架输送系统包括细长的递送导管，其包括固定到导管的内部管状构件的加强系绳构件。 系绳构件具有从远侧末端构件螺旋地延伸的远端长度或邻近导管的远侧末端构件的近端的部分，以及也沿轴向延伸穿过导管的支架保持器区域的部分。 该加强系绳构件为导管提供增强的拉伸强度。

公开(公告)号：US08216296B2

公开(公告)日：2012-07-10

申请号：US11613827

申请日：2006-12-20

Applicant: Patrick P. Wu ,  Keif Fitzgerald ,  August Yambao ,  Michael Green

Inventor： Patrick P. Wu ,  Keif Fitzgerald ,  August Yambao ,  Michael Green

IPC: A61F2/84

CPC classification number: A61F2/95 ,  A61F2/966 ,  A61F2002/9517 ,  A61M2025/0098

Abstract: The invention is directed a delivery system for implantation a self-expanding medical device in a body which includes a control handle and a catheter portion. The catheter portion includes an outer restraining member which covers the collapsed, medical device, an inner catheter member having a distal end including a region upon which the medical device is mounted, and an outer sheath which is removably attached to the control handle. The outer sheath creates a conduit for the catheter portion to prevent the inner catheter member from moving axially when the outer restraining member is retracted. The control handle has a rotatable thumbwheel to actuate a retraction mechanism attached to the proximal end of the outer restraining member which moves the restraining member in a proximal direction to deploy the medical device.

Abstract translation: 本发明涉及一种用于在包括控制手柄和导管部分的身体中植入自扩张医疗装置的递送系统。 所述导管部分包括覆盖所述收缩的医疗装置的外限制构件，具有包括安装所述医疗装置的区域的远端的内导管构件和可移除地附接到所述控制手柄的外护套。 当外部限制构件缩回时，外护套产生用于导管部分的导管，以防止内部导管构件轴向移动。 控制手柄具有可旋转的指轮，以致动附接到外约束构件的近端的缩回机构，该缩回机构沿约束方向移动约束构件以展开医疗装置。

公开(公告)号：US20110313509A1

公开(公告)日：2011-12-22

申请号：US12820694

申请日：2010-06-22

Applicant: Keif Fitzgerald ,  Boris Anukhin

Inventor： Keif Fitzgerald ,  Boris Anukhin

IPC: A61F2/82

CPC classification number: A61F2/915 ,  A61F2/844 ,  A61F2002/91575

Abstract: A stent having a compacted configuration in which adjacent crowns of its undulating rings overlap one another. The overlapping compacted configuration provides for a relatively low profile in view of the coverage that is achieved by the stent upon expansion.

Abstract translation: 具有压实构造的支架，其中其起伏环的相邻冠彼此重叠。 考虑到扩张时支架实现的覆盖范围，重叠的压实构型提供了相对低的轮廓。

公开(公告)号：US07938843B2

公开(公告)日：2011-05-10

申请号：US10457218

申请日：2003-06-09

Applicant: John F. Boylan ,  Keif Fitzgerald ,  Zhi Cheng Lin

Inventor： John F. Boylan ,  Keif Fitzgerald ,  Zhi Cheng Lin

IPC: A61M29/00 ,  A61F11/00

CPC classification number: A61F2/013 ,  A61F2002/018 ,  A61F2210/0023 ,  A61F2230/0006 ,  A61F2230/0067 ,  A61M2025/09141 ,  C22F1/006

Abstract: Cold worked nickel-titanium alloys that have linear pseudoelastic behavior without a phase transformation or onset of stress-induced martensite as applied to a medical device having a strut formed body deployed from a sheath is disclosed. In one application, an embolic protection device that employs a linear pseudoelastic nitinol self-expanding strut assembly with a small profile delivery system for use with interventional procedures is disclosed. The expandable strut assembly is covered with a filter element and both are compressed into a restraining sheath for delivery to a deployment site downstream and distal to an interventional procedure. Once at the desired site, the restraining sheath is retracted to deploy the embolic protection device, which captures flowing emboli generated during the interventional procedure. Linear pseudoelastic nitinol is used in the medical device as distinct from non-linear pseudoelastic (i.e., superelastic) nitinol.

Abstract translation: 公开了一种冷加工的镍 - 钛合金，其具有线性假弹性特性，而不会发生应变诱发马氏体的相变或起始应用于具有从护套展开的支柱成形体的医疗装置。 在一个应用中，公开了一种栓塞保护装置，其采用线性假弹性镍钛诺自扩张支架组件，其具有用于介入程序的小型轮廓输送系统。 可膨胀支柱组件被过滤元件覆盖，并且两者被压缩成约束护套，用于递送到介入过程下游和远端的部署部位。 一旦在期望的位置，约束护套被缩回以部署栓塞保护装置，其捕获在介入手术期间产生的流动栓塞。 在医疗装置中使用线性假弹性镍钛诺不同于非线性假弹性（即超弹性）镍钛诺。

公开(公告)号：US07867271B2

公开(公告)日：2011-01-11

申请号：US10720032

申请日：2003-11-20

Applicant: Timothy A. Geiser ,  Charles R. Peterson ,  Andy Denison ,  Stephanie Klocke ,  Samir Patel ,  Joanna Lubas ,  Joanne Lumauig ,  Kathy Lind ,  Keif Fitzgerald

Inventor： Timothy A. Geiser ,  Charles R. Peterson ,  Andy Denison ,  Stephanie Klocke ,  Samir Patel ,  Joanna Lubas ,  Joanne Lumauig ,  Kathy Lind ,  Keif Fitzgerald

IPC: A61F2/06

CPC classification number: A61F2/95 ,  A61F2/966 ,  A61M2025/0183

Abstract: A catheter assembly is provided having an inner member and an outer member extending along a longitudinal axis, the inner member and the outer member having a coaxial configuration and dimensioned for relative axial movement. The outer member may include an anti rotation member adapted to engage with a longitudinal slot formed on the inner member so as to maintain rotational alignment between inner member and outer member. The inner member can be made with a proximal portion made from a tubing such as hypotubing or a coil tubing. The inner member also may be made with a proximal portion made with a support mandrel. A coil tubing can be utilized to form the guide wire receiving member which is attached to the inner member.

Abstract translation: 提供导管组件，其具有内部构件和沿着纵向轴线延伸的外部构件，内部构件和外部构件具有同轴构造并且被设计成用于相对轴向移动。 外部构件可以包括防旋转构件，其适于与形成在内部构件上的纵向狭槽接合，以便保持内部构件和外部构件之间的旋转对准。 内部构件可以由具有诸如假面或管线管的管子制成的近端部分制成。 内部构件也可以由具有支撑心轴的近端部分制成。 可以使用线圈管来形成附接到内部构件的导丝接收构件。

公开(公告)号：US20100331951A1

公开(公告)日：2010-12-30

申请号：US12857467

申请日：2010-08-16

Applicant: Nianjiong Joan Bei ,  Keif Fitzgerald ,  Patrick C. Saxton ,  Zhicheng Lin ,  Steven A. Tyler ,  Joanna Lubas

Inventor： Nianjiong Joan Bei ,  Keif Fitzgerald ,  Patrick C. Saxton ,  Zhicheng Lin ,  Steven A. Tyler ,  Joanna Lubas

IPC: A61F2/82 ,  A61M29/00

CPC classification number: A61F2/958 ,  A61F2/013 ,  A61F2002/011 ,  A61F2002/018 ,  A61F2002/9583 ,  A61F2230/0006 ,  A61F2230/008

Abstract: A catheter system and method for implanting an endoprosthesis such as a stent at a treatment site in a patient's body lumen. The catheter provides a complete system for stent delivery, dilatation, and delivery and/or recovery of an expandable device, such as an embolic protection device, adjacent to the treatment site in the body lumen.

Abstract translation: 用于在患者体腔内的治疗部位植入诸如支架的内假体的导管系统和方法。 该导管提供了用于支架输送，扩张，以及邻近体腔内治疗部位的可扩张装置（例如栓塞保护装置）的递送和/或回收的完整系统。

公开(公告)号：US20100145433A1

公开(公告)日：2010-06-10

申请号：US12571198

申请日：2009-09-30

Applicant: Boris Anukhin ,  Keif Fitzgerald

Inventor： Boris Anukhin ,  Keif Fitzgerald

IPC: A61F2/82

CPC classification number: A61F2/91 ,  A61F2/88 ,  A61F2/915 ,  A61F2002/825 ,  A61F2002/828 ,  A61F2002/91558 ,  A61F2210/0076 ,  A61F2230/0054

Abstract: Example embodiments include an endoprosthesis that has a first annular segment that is radially expandable and a second annular segment that is also radially expandable. An axial segment, which includes one or more struts, is operatively associated with the first annular segment and the second annular segment to maintain a specified distance between the first annular segment and the second annular segment.

Abstract translation: 示例性实施例包括具有径向可扩张的第一环形段和也可径向扩张的第二环形段的内假体。 包括一个或多个支柱的轴向段与第一环形区段和第二环形区段可操作地相关联，以在第一环形区段和第二环形区段之间保持特定距离。