公开(公告)号：US08323330B2

公开(公告)日：2012-12-04

申请号：US12820694

申请日：2010-06-22

Applicant: Keif Fitzgerald ,  Boris Anukhin

Inventor： Keif Fitzgerald ,  Boris Anukhin

IPC: A61F2/06

CPC classification number: A61F2/915 ,  A61F2/844 ,  A61F2002/91575

Abstract: A stent having a compacted configuration in which adjacent crowns of its undulating rings overlap one another. The overlapping compacted configuration provides for a relatively low profile in view of the coverage that is achieved by the stent upon expansion.

Abstract translation: 具有压实构造的支架，其中其起伏环的相邻冠彼此重叠。 考虑到扩张时支架实现的覆盖范围，重叠的压实构型提供了相对低的轮廓。

公开(公告)号：US08252041B2

公开(公告)日：2012-08-28

申请号：US11844235

申请日：2007-08-23

Applicant: Hao-Ming Hsiao ,  Keif Fitzgerald ,  Boris Anukhin

Inventor： Hao-Ming Hsiao ,  Keif Fitzgerald ,  Boris Anukhin

IPC: A61F2/06

CPC classification number: A61F2/06 ,  A61F2/91 ,  A61F2/915 ,  A61F2002/91558 ,  A61F2002/91575 ,  A61F2230/0013

Abstract: Stent designs for use in peripheral vessels, such as the carotid arteries, are disclosed. The stents consist of a plurality of radially expandable cylindrical elements generally aligned on a common longitudinal stent axis and interconnected by one or more interconnecting members placed so that the stent is flexible in a longitudinal direction. The cylindrical elements are generally serpentine wave pattern transverse to the longitudinal axis between alternating valley portion and peak portions, the valley portion including alternating double-curved portions and U-shaped portions. The interconnecting members are attached to the double-curved portions to connect a cylindrical element to an adjacent cylindrical element and interconnecting members are attached to the U-shaped portions to connect the cylindrical element to the other adjacent cylindrical element. The designs include an eight crown and six crown stent which exhibit flexibility and sufficient radial strength to support the vessel.

Abstract translation: 公开了用于外周血管例如颈动脉的支架设计。 支架由多个可径向扩张的圆柱形元件组成，其大体上在公共的纵向支架轴线上对准，并且通过一个或多个相互连接的构件相互连接，以使支架在纵向方向上是柔性的。 圆柱形元件通常是在交替的谷部分和峰部分之间横向于纵向轴线的蛇形波形图案，谷部分包括交替的双曲面部分和U形部分。 互连构件附接到双曲面部分以将圆柱形元件连接到相邻的圆柱形元件，并且互连构件附接到U形部分以将圆柱形元件连接到另一相邻圆柱形元件。 这些设计包括八冠和六冠支架，其具有弹性和足够的径向强度以支撑血管。

公开(公告)号：US20100193485A1

公开(公告)日：2010-08-05

申请号：US12757842

申请日：2010-04-09

Applicant: Boris Anukhin ,  Larry Baughman ,  Pamela A. Kramer-Brown ,  Neil Burkhart ,  Li Chen ,  Duane M. DeMore ,  Keif Fitzgerald ,  Gregory W. Johnson ,  Z. C. Lin ,  David Mackiewicz ,  Karim S. Osman ,  Randolf Von Oepen ,  William E. Webler, JR. ,  Travis R. Yribarren

Inventor： Boris Anukhin ,  Larry Baughman ,  Pamela A. Kramer-Brown ,  Neil Burkhart ,  Li Chen ,  Duane M. DeMore ,  Keif Fitzgerald ,  Gregory W. Johnson ,  Z. C. Lin ,  David Mackiewicz ,  Karim S. Osman ,  Randolf Von Oepen ,  William E. Webler, JR. ,  Travis R. Yribarren

IPC: B23K26/18

CPC classification number: B23K26/4005 ,  A61F2/07 ,  A61F2/91 ,  B23K26/16 ,  B23K26/38 ,  B23K26/40 ,  B23K26/402 ,  B23K2101/04 ,  B23K2101/06 ,  B23K2103/50

Abstract: Methods for making devices include providing a tubular member to be formed into a device, placing a removable sacrificial block material in the lumen of the tubular member and laser cutting the tubular member. A doping material can be added to the melted portion of the tubular member to promote the formation of brittle slag. A fixture can be used to hold a cut workpiece in order to ream sacrificial material from the surface of the workpiece. Pressurized gas can be supplied to the inner lumen of the tubular member to cause slag to form on the outside surface, rather than the inner surface, of the tubular member. A tubular member made from nickel-titanium alloy can be tightly adhered to a sacrificial sleeve utilizing the phase changes associated with nickel-titanium. A rotating mandrel can be placed within the lumen of the tubular member during laser cutting. A mandrel which includes an enlarged diameter section causes the workpiece to expand slightly within its elastic deformation range to dislodge islands from the workpiece. Such a mandrel could be formed from a tubular member which has a central lumen that can be used to deliver a pressurized medium to “blast” islands from the workpiece.

Abstract translation: 制造装置的方法包括提供要形成装置的管状构件，将可移除的牺牲块材料放置在管状构件的内腔中并激光切割管状构件。 可以将掺杂材料添加到管状构件的熔融部分中以促进脆性炉渣的形成。 夹具可用于夹持切割的工件，以便从工件的表面获得牺牲材料。 加压气体可以供应到管状构件的内腔，以在管状构件的外表面而不是内表面上形成炉渣。 利用与镍 - 钛相关联的相变，由镍 - 钛合金制成的管状部件可以紧密地粘附到牺牲套管上。 在激光切割期间，旋转心轴可以放置在管状构件的内腔内。 包括扩大直径部分的心轴使得工件在其弹性变形范围内稍微膨胀以从工件移除岛。 这种心轴可以由管状构件形成，该管状构件具有可用于将加压介质输送到工件的“鼓风”岛的中心腔。

公开(公告)号：US20100145431A1

公开(公告)日：2010-06-10

申请号：US12703535

申请日：2010-02-10

Applicant: Patrick P. Wu ,  Keif Fitzgerald ,  August Yambao ,  Michael Green

Inventor： Patrick P. Wu ,  Keif Fitzgerald ,  August Yambao ,  Michael Green

IPC: A61F2/84

CPC classification number: A61F2/95 ,  A61F2/966 ,  A61F2002/9517 ,  A61M2025/0098

Abstract: The invention is directed a delivery system for implantation a self-expanding medical device in a body which includes a control handle and a catheter portion. The catheter portion includes an outer restraining member which covers the collapsed, medical device, an inner catheter member having a distal end including a region upon which the medical device is mounted, and an outer sheath which is removably attached to the control handle. The outer sheath creates a conduit for the catheter portion to prevent the inner catheter member from moving axially when the outer restraining member is retracted. The control handle has a rotatable thumbwheel to actuate a retraction mechanism attached to the proximal end of the outer restraining member which moves the restraining member in a proximal direction to deploy the medical device.

Abstract translation: 本发明涉及一种用于在包括控制手柄和导管部分的身体中植入自扩张医疗装置的递送系统。 所述导管部分包括覆盖所述收缩的医疗装置的外限制构件，具有包括安装所述医疗装置的区域的远端的内导管构件和可移除地附接到所述控制手柄的外护套。 当外部限制构件缩回时，外护套产生用于导管部分的导管，以防止内部导管构件轴向移动。 控制手柄具有可旋转的指轮，以致动附接到外约束构件的近端的缩回机构，该缩回机构沿约束方向移动约束构件以展开医疗装置。

公开(公告)号：US20080051877A1

公开(公告)日：2008-02-28

申请号：US11844235

申请日：2007-08-23

Applicant: Hao-Ming Hsiao ,  Keif Fitzgerald ,  Boris Anukhin

Inventor： Hao-Ming Hsiao ,  Keif Fitzgerald ,  Boris Anukhin

IPC: A61F2/82

CPC classification number: A61F2/06 ,  A61F2/91 ,  A61F2/915 ,  A61F2002/91558 ,  A61F2002/91575 ,  A61F2230/0013

Abstract: Stent designs for use in peripheral vessels, such as the carotid arteries, are disclosed. The stents consist of a plurality of radially expandable cylindrical elements generally aligned on a common longitudinal stent axis and interconnected by one or more interconnecting members placed so that the stent is flexible in a longitudinal direction. The cylindrical elements are generally serpentine wave pattern transverse to the longitudinal axis between alternating valley portion and peak portions, the valley portion including alternating double-curved portions and U-shaped portions. The interconnecting members are attached to the double-curved portions to connect a cylindrical element to an adjacent cylindrical element and interconnecting members are attached to the U-shaped portions to connect the cylindrical element to the other adjacent cylindrical element. The designs include an eight crown and six crown stent which exhibit flexibility and sufficient radial strength to support the vessel.

Abstract translation: 公开了用于外周血管例如颈动脉的支架设计。 支架由多个可径向扩张的圆柱形元件组成，其大体上在公共的纵向支架轴线上对准，并且通过一个或多个相互连接的构件相互连接，以使支架在纵向方向上是柔性的。 圆柱形元件通常是在交替的谷部分和峰部分之间横向于纵向轴线的蛇形波形图案，谷部分包括交替的双曲面部分和U形部分。 互连构件附接到双曲面部分以将圆柱形元件连接到相邻的圆柱形元件，并且互连构件附接到U形部分以将圆柱形元件连接到另一相邻圆柱形元件。 这些设计包括八冠和六冠支架，其具有弹性和足够的径向强度以支撑血管。

公开(公告)号：US20050113902A1

公开(公告)日：2005-05-26

申请号：US10720032

申请日：2003-11-20

Applicant: Timothy Geiser ,  Charles Peterson ,  Andy Denison ,  Stephanie Klocke ,  Samir Patel ,  Joanna Lubas ,  Joanne Lumauig ,  Kathy Lind ,  Keif Fitzgerald

Inventor： Timothy Geiser ,  Charles Peterson ,  Andy Denison ,  Stephanie Klocke ,  Samir Patel ,  Joanna Lubas ,  Joanne Lumauig ,  Kathy Lind ,  Keif Fitzgerald

IPC: A61F2/84 ,  A61L29/00 ,  A61M25/00 ,  A61F2/06

CPC classification number: A61F2/95 ,  A61F2/966 ,  A61M2025/0183

Abstract: A catheter assembly is provided having an inner member and an outer member extending along a longitudinal axis, the inner member and the outer member having a coaxial configuration and dimensioned for relative axial movement. The outer member may include an anti rotation member adapted to engage with a longitudinal slot formed on the inner member so as to maintain rotational alignment between inner member and outer member. The inner member can be made with a proximal portion made from a tubing such as hypotubing or a coil tubing. The inner member also may be made with a proximal portion made with a support mandrel. A coil tubing can be utilized to form the guide wire receiving member which is attached to the inner member.

Abstract translation: 提供导管组件，其具有内部构件和沿着纵向轴线延伸的外部构件，内部构件和外部构件具有同轴构造并且被设计成用于相对轴向移动。 外部构件可以包括防旋转构件，其适于与形成在内部构件上的纵向狭槽接合，以便保持内部构件和外部构件之间的旋转对准。 内部构件可以由具有诸如假面或管线管的管子制成的近端部分制成。 内部构件也可以由具有支撑心轴的近端部分制成。 可以使用线圈管来形成附接到内部构件的导丝接收构件。

公开(公告)号：US20050090890A1

公开(公告)日：2005-04-28

申请号：US10946944

申请日：2004-09-22

Applicant: Patrick Wu ,  Keif Fitzgerald ,  Stephanie Klocke

Inventor： Patrick Wu ,  Keif Fitzgerald ,  Stephanie Klocke

IPC: A61F2/06 ,  A61F2/84 ,  A61F11/00 ,  A61M29/00

CPC classification number: A61M25/0023 ,  A61F2/95 ,  A61F2/966 ,  A61F2002/9517 ,  A61M25/0021 ,  A61M2025/006 ,  A61M2025/0062 ,  A61M2025/0098 ,  A61M2025/0183 ,  A61M2025/0681

Abstract: The invention is directed to a delivery system for implantation a self-expanding medical device in a body which includes a control handle and a catheter portion. The catheter portion includes an outer restraining member which covers the collapsed, medical device, an inner catheter member having a distal end including a region upon which the medical device is mounted, and an outer sheath which is removably attached to the control handle. The outer sheath creates a conduit for the catheter portion to prevent the inner catheter member from moving axially when the outer restraining member is retracted. The control handle has a rotatable thumbwheel to actuate a retraction mechanism attached to the proximal end of the outer restraining member which moves the restraining member in a proximal direction to deploy the medical device.

Abstract translation: 本发明涉及一种用于将自扩张医疗装置植入体内的递送系统，其包括控制手柄和导管部分。 所述导管部分包括覆盖所述收缩的医疗装置的外限制构件，具有包括安装所述医疗装置的区域的远端的内导管构件和可移除地附接到所述控制手柄的外护套。 当外部限制构件缩回时，外护套产生用于导管部分的导管，以防止内部导管构件轴向移动。 控制手柄具有可旋转的指轮，以致动附接到外约束构件的近端的缩回机构，该缩回机构沿约束方向移动约束构件以展开医疗装置。

公开(公告)号：US08974514B2

公开(公告)日：2015-03-10

申请号：US11724089

申请日：2007-03-13

Applicant: Boris Anukhin ,  Hao-Ming Hsiao ,  Keif Fitzgerald

Inventor： Boris Anukhin ,  Hao-Ming Hsiao ,  Keif Fitzgerald

IPC: A61F2/06 ,  A61F2/915

CPC classification number: A61F2/915 ,  A61F2002/91541 ,  A61F2002/91583 ,  A61F2230/0054 ,  A61F2250/0036

Abstract: An expandable stent is implanted in a body lumen, such as a coronary artery, peripheral artery, or other body lumen. The stent includes a plurality of rings connected by links. The stent has a high degree of flexibility in the longitudinal direction, yet has adequate vessel wall coverage and radial strength sufficient to hold open an artery or other body lumen. The stent can be compressed or crimped onto a catheter to a very low profile since links are integrally formed from a portion of the struts forming the rings. The stent is constructed so that the cylindrical rings are very close together in order to provide maximum scaffolding, and if the stent has a drug coating, to provide a uniform drug delivery over the length of the stent. The connecting links are integrally formed from a portion of the struts forming the rings so that the links can have a maximum length thereby providing increased longitudinal flexibility of the stent.

Abstract translation: 可扩张支架植入体腔，例如冠状动脉，外周动脉或其他体腔。 支架包括通过连杆连接的多个环。 支架在纵向具有高度的柔性，但具有足够的容器壁覆盖和径向强度足以保持打开动脉或其他体腔。 支架可以被压缩或卷曲到导管上以非常低的轮廓，因为连杆由形成环的支柱的一部分整体形成。 支架被构造成使得圆柱形环非常靠近在一起以便提供最大的脚手架，并且如果支架具有药物涂层，以在支架的长度上提供均匀的药物递送。 连接连杆由形成环的支柱的一部分整体形成，使得连杆可以具有最大长度，从而提供支架的增加的纵向柔性。

公开(公告)号：US07776080B2

公开(公告)日：2010-08-17

申请号：US11739743

申请日：2007-04-25

Applicant: Nianjiong Joan Bei ,  Keif Fitzgerald ,  Patrick C. Saxton ,  Zhicheng Lin ,  Steven A. Tyler ,  Joanna Lubas

Inventor： Nianjiong Joan Bei ,  Keif Fitzgerald ,  Patrick C. Saxton ,  Zhicheng Lin ,  Steven A. Tyler ,  Joanna Lubas

IPC: A61F2/06

CPC classification number: A61F2/958 ,  A61F2/013 ,  A61F2002/011 ,  A61F2002/018 ,  A61F2002/9583 ,  A61F2230/0006 ,  A61F2230/008

Abstract: A catheter system and method for implanting an endoprosthesis such as a stent at a treatment site in a patient's body lumen. The catheter provides a complete system for stent delivery, dilatation, and delivery and/or recovery of an expandable device, such as an embolic protection device, adjacent to the treatment site in the body lumen.

Abstract translation: 用于在患者体腔内的治疗部位植入诸如支架的内假体的导管系统和方法。 该导管提供了用于支架输送，扩张，以及邻近体腔内治疗部位的可扩张装置（例如栓塞保护装置）的递送和/或回收的完整系统。

公开(公告)号：US07758625B2

公开(公告)日：2010-07-20

申请号：US10661406

申请日：2003-09-12

Applicant: Patrick P. Wu ,  Keif Fitzgerald ,  August Yambao ,  Michael Green

Inventor： Patrick P. Wu ,  Keif Fitzgerald ,  August Yambao ,  Michael Green

IPC: A61F2/06

CPC classification number: A61F2/95 ,  A61F2/966 ,  A61F2002/9517 ,  A61M2025/0098

Abstract: A delivery system for implantation a self-expanding medical device in a body includes a control handle and a catheter portion. The catheter portion includes an outer restraining member which covers the collapsed, medical device, an inner catheter member having a distal end including a region upon which the medical device is mounted, and an outer sheath removably attached to the control handle. The outer sheath creates a conduit for the catheter portion to prevent the inner catheter member from moving axially when the outer restraining member is retracted. The control handle has a rotatable thumbwheel to actuate a retraction mechanism attached to the proximal end of the outer restraining member which moves the restraining member in a proximal direction to deploy the medical device.

Abstract translation: 用于将自扩张医疗装置植入体内的输送系统包括控制手柄和导管部分。 导管部分包括覆盖塌陷的医疗装置的外限制构件，具有包括安装有医疗装置的区域的远端的内导管构件和可移除地附接到控制手柄的外护套。 当外部限制构件缩回时，外护套产生用于导管部分的导管，以防止内部导管构件轴向移动。 控制手柄具有可旋转的指轮，以致动附接到外约束构件的近端的缩回机构，该缩回机构沿约束方向移动约束构件以展开医疗装置。