公开(公告)号：US08206643B2

公开(公告)日：2012-06-26

申请号：US12676856

申请日：2008-09-01

申请人： Jussi Sipilä ,  Kaarle Peltoniemi ,  Peter Björklund ,  Jiliang Xia

发明人： Jussi Sipilä ,  Kaarle Peltoniemi ,  Peter Björklund ,  Jiliang Xia

IPC分类号： F27D3/18

CPC分类号： C22B15/0047 ,  F27D3/16 ,  F27D3/18

摘要： A concentrate burner for feeding a pulverous concentrate mixture and reaction gas into a reaction shaft of a flash smelting furnace. The concentrate burner includes a feeder pipe for feeding a concentrate mixture into the reaction shaft and a dispersing device for directing dispersing gas to the concentrate mixture flowing around the dispersing device. For feeding the reaction gas into the reaction shaft, a gas supply device is provided which includes a reaction gas chamber for mixing the reaction gas with the concentrate mixture, and for directing the concentrate mixture to the side by the dispersing gas. The reaction gas chamber includes a turbulent flow chamber, to which an inlet channel opens tangentially for directing the reaction gas to the reaction gas chamber in a tangential direction. In the inlet channel, an adjusting member is arranged for adjusting the cross-sectional area of the reaction gas flow.

摘要翻译： 用于将粉状浓缩物混合物和反应气体进料到闪蒸熔炉的反应轴中的浓缩燃烧器。 浓缩燃烧器包括用于将浓缩物混合物供入到反应轴中的进料管和用于将分散气体引导到围绕分散装置流动的浓缩物混合物的分散装置。 为了将反应气体输送到反应器中，提供了一种气体供给装置，其包括用于将反应气体与浓缩物混合物混合的反应气体室，并且通过分散气体将浓缩物混合物引导到侧面。 反应气室包括湍流室，入口通道朝向其中切向引导，以将反应气体沿切线方向引导到反应气室。 在入口通道中，布置调节构件以调节反应气流的横截面积。

公开(公告)号：US06716968B2

公开(公告)日：2004-04-06

申请号：US09915306

申请日：2001-07-27

申请人： Viveka Björklund ,  Bertil Björklund ,  Peter Björklund ,  Marius Nap ,  Frans C. S. Ramaekers ,  Bert Schutte

发明人： Viveka Björklund ,  Bertil Björklund ,  Peter Björklund ,  Marius Nap ,  Frans C. S. Ramaekers ,  Bert Schutte

IPC分类号： C07K1618

CPC分类号： C07K5/1021 ,  A61K38/00 ,  C07K14/4741 ,  C07K14/4747 ,  C07K16/18

摘要： Apoptosis-related antigenic compounds comprising an exposed antigenic site having the amino acid sequence SEQ ID NO: 1: Glu Asp Phe Asn Leu Gly Asp Ala Leu Asp 1               5                    10 or a functionally equivalent sequence comprising at least the sequence Ala Leu Asp are disclosed. Further, several applications and uses based on such compounds are included, such as use of the compounds in medicaments, nucleic acid sequences encoding the amino-acid sequence of such a peptide compound or protein fragment comprising the C-terminal amino acid sequence Ala Leu Asp, anti-sense nucleic acid sequence, vector comprising such a nucleic acid sequence, antibody or antigen-binding peptide recognizing such an antigenic compound and use thereof in a medicament, agents regulating the liberation of protein fragments comprising the amino-acid sequence SEQ ID NO: 1 or functionally equivalent sequences comprising the C-terminal amino acid sequence Ala Leu Asp, a method of determining the occurrence of cell apoptosis in a sample of biological material, especially in the diagnosis of degenerative diseases and cancer, or monitoring of the effect of therapy, a method of treating diseases with involvement of apoptosis, such as cancer and degenerative diseases, a method of creating cancer cells, and as carrier for prophylactic, therapeutic or diagnostic use.

摘要翻译： 公开了包含具有氨基酸序列的暴露的抗原位点或至少包含序列Ala Leu Asp的功能等同序列的凋亡相关抗原化合物。 此外，包括基于这些化合物的几种应用和用途，例如在药物中使用化合物，编码这种肽化合物的氨基酸序列的核酸序列或包含C-末端氨基酸序列Ala Leu Asp的蛋白质片段 ，反义核酸序列，包含这种核酸序列的载体，识别这种抗原性化合物的抗体或抗原结合肽及其在药物中的用途，调节释放包含氨基酸序列SEQ ID NO ：1或包含C-末端氨基酸序列Ala Leu Asp的功能等同序列，确定生物材料样品中细胞凋亡发生的方法，特别是在退行性疾病和癌症的诊断中，或监测其作用 治疗，涉及凋亡的疾病如癌症和退行性疾病的方法，一种产生癌症的方法 细胞，以及作为预防，治疗或诊断用途的载体。

公开(公告)号：US20130328250A1

公开(公告)日：2013-12-12

申请号：US13882728

申请日：2011-11-03

申请人： Jorma Myyri ,  Tapio Ahokainen ,  Lauri P. Pesonen ,  Peter Björklund

发明人： Jorma Myyri ,  Tapio Ahokainen ,  Lauri P. Pesonen ,  Peter Björklund

IPC分类号： F27D9/00 ,  F27D3/16 ,  C22B5/00

CPC分类号： F27D9/00 ,  C22B5/00 ,  C22B15/0047 ,  F27D3/16

摘要： The invention relates to a method for controlling the thermal balance of a suspension smelting and to a suspension smelting furnace. The suspension smelting furnace, comprising a reaction shaft (1), a lower furnace (2), and an uptake (3), wherein the reaction shaft (1) having a shaft structure (4) that is provided with a surrounding wall structure (5) and a roof structure (6) and that limits a reaction chamber (7), and wherein the reaction shaft (1) is provided with a concentrate burner (14) for feeding pulverous solid matter and reaction gas into the reaction chamber (7). The shaft structure (4) of the reaction shaft (1) is provided with cooling means (8) for feeding endothermic material into the reaction chamber (7) of the reaction shaft (1).

摘要翻译： 本发明涉及一种用于控制悬浮熔炼和悬浮熔炼炉的热平衡的方法。 所述悬浮熔炼炉包括反应轴（1），下炉（2）和吸收（3），其中所述反应轴（1）具有设置有周围壁结构的轴结构（4） 5）和屋顶结构（6），并且限制了反应室（7），并且其中反应轴（1）设置有用于将粉状固体物质和反应气体进料到反应室（7）中的浓缩燃烧器（14） ）。 反应轴（1）的轴结构（4）设有用于将吸热材料供给到反应轴（1）的反应室（7）中的冷却装置（8）。

公开(公告)号：US20120200012A1

公开(公告)日：2012-08-09

申请号：US13502523

申请日：2010-10-19

申请人： Jussi Sipilä ,  Markku Lahtinen ,  Peter Björklund ,  Kaarle Peltoniemi ,  Tapio Ahokainen ,  Lauri P. Pesonen ,  Kaj Eklund

发明人： Jussi Sipilä ,  Markku Lahtinen ,  Peter Björklund ,  Kaarle Peltoniemi ,  Tapio Ahokainen ,  Lauri P. Pesonen ,  Kaj Eklund

IPC分类号： C22B9/16 ,  F27D3/00

CPC分类号： C22B5/14 ,  C22B5/12 ,  C22B15/00 ,  F27B15/10 ,  F27B15/14 ,  F27D3/16 ,  F27D3/18

摘要： The invention relates to a method of using a suspension smelting furnace and to a suspension smelting furnace and to a concentrate burner (4). The concentrate burner (4) comprises a first gas supply device (12) for feeding a first gas (5) into the reaction shaft (2) and a second gas supply device (18) for feeding a second gas (16) into the reaction shaft (2). The first gas supply device (12) comprises a first annular discharge opening (14), which which is arranged concentrically with the mouth (8) of a feeder pipe (7), so that the first annular discharge opening (14) surrounds the feeder pipe (7). The second gas supply device (18) comprises a second annular discharge opening (17), which is arranged concentrically with the mouth (8) of the feeder pipe (7), so that the second annular discharge opening (17) surrounds the feeder pipe (7) opening (14).

摘要翻译： 本发明涉及一种使用悬浮熔炼炉和悬浮熔炼炉和浓缩燃烧器（4）的方法。 浓缩燃烧器（4）包括用于将第一气体（5）供给到反应轴（2）中的第一气体供应装置（12）和用于将第二气体（16）进料到反应器中的第二气体供应装置（18） 轴（2）。 第一气体供给装置（12）包括与进料管（7）的口（8）同心设置的第一环形排出口（14），使得第一环形排出口（14）围绕进料器 管（7）。 第二气体供给装置（18）包括与进料管（7）的口（8）同心设置的第二环形排出口（17），使得第二环形排出口（17）围绕进料管 （7）开口（14）。

公开(公告)号：US09869515B2

公开(公告)日：2018-01-16

申请号：US13807211

申请日：2011-06-28

申请人： Peter Björklund ,  Kaarle Peltoniemi ,  Mikael Jåfs ,  Tapio Ahokainen ,  Kari Pienimäki ,  Lauri P. Pesonen

发明人： Peter Björklund ,  Kaarle Peltoniemi ,  Mikael Jåfs ,  Tapio Ahokainen ,  Kari Pienimäki ,  Lauri P. Pesonen

IPC分类号： F27B1/02 ,  F27D3/00 ,  F27D9/00 ,  C22B15/00 ,  F27B19/04

CPC分类号： F27B1/02 ,  C22B15/0047 ,  F27B19/04 ,  F27D3/0025 ,  F27D9/00

摘要： The invention relates to a suspension smelting furnace comprising a reaction shaft (1), an uptake shaft (2), and a lower furnace (3), as well as a concentrate burner (4) for feeding reaction gas and fine solids into the reaction shaft (1) of the suspension smelting furnace. The concentrate burner (4) comprises a fine solids discharge channel (5) that is radially limited by the wall (6) of the solids discharge channel, a fine solids dispersion device (7) in the fine solids discharge channel (5), an annular reaction gas channel (8) that surrounds the fine solids discharge channel (5) and is radially limited by the wall (9) of the annular reaction gas channel (8), and a cooling block (10) that surrounds the annular reaction gas channel (8). The cooling block (10) is a component that is manufactured by a continuous casting method. The cooling block (10) is attached to the arch (11) of the reaction shaft (1) and the wall (9) of the annular reaction gas channel (8), so that the discharge orifice (12) of the annular reaction gas channel (8) is formed between a structure (13), which is jointly formed by the cooling block (10) and the wall (9) of the annular reaction gas channel (8), and the wall (6) of the solids discharge channel. The invention also relates to a concentrate burner (4) for feeding reaction gas and fine solids into the reaction shaft (1) of a suspension smelting furnace.

公开(公告)号：US09557105B2

公开(公告)日：2017-01-31

申请号：US14360663

申请日：2011-11-29

申请人： Peter Björklund

发明人： Peter Björklund

IPC分类号： F26B3/00 ,  C10L5/44 ,  C10L9/08 ,  C10L5/36

CPC分类号： F26B3/00 ,  C10L5/363 ,  C10L5/442 ,  C10L9/083 ,  Y02E50/10 ,  Y02E50/15 ,  Y02E50/30

摘要： The improved method and arrangement are for cooling torrefied lignocellulosic material. By adding water in controlled amounts to the torrefied material in a grinder at exit from a roaster the entire volume of torrefied material could be cooled down to a temperature well below the critical temperature without increasing the water content of the final product.

摘要翻译： 改进的方法和布置用于冷却烘焙的木质纤维素材料。 通过在焙烧炉出口处将受控量的水加入研磨机中的烘焙材料，可以将整个体积的烘焙材料冷却到远低于临界温度的温度，而不增加最终产品的含水量。

公开(公告)号：US09266917B2

公开(公告)日：2016-02-23

申请号：US14125616

申请日：2011-06-22

申请人： Peter Björklund ,  Martin Wimby ,  Henrik Wallmo

发明人： Peter Björklund ,  Martin Wimby ,  Henrik Wallmo

IPC分类号： D21C11/00 ,  C07G1/00 ,  C08H8/00 ,  C08H7/00

CPC分类号： C07G1/00 ,  C08H6/00 ,  C08H8/00 ,  D21C11/0007 ,  Y02P40/44

摘要： The method is for separation of lignin from original black liquor (BLIN) having the following phases in sequence; a first precipitation phase (PR1) for precipitation of lignin by a first acidification of the original black liquor by adding a first acid or mixture of acids (G1a); followed by a second precipitation phase (PR2) for precipitation of lignin by a further acidification of the original black liquor by adding a second acid or mixture of acids (G1b). The first phase is implemented to lower the pH while avoiding any larger amount of precipitation, i.e. less than 2-5%, while the second phase is implemented in order to obtain the larger part of the precipitation. In total is 40-70% of the total lignin content of the original black liquor precipitated while the residual black liquor after precipitation is still strongly alkaline.

摘要翻译： 该方法是将木质素与依次具有以下相的原黑液（BLIN）分离; 用于通过加入第一种酸或酸的混合物（G1a）首次酸化原始黑液来沉淀木质素的第一沉淀相（PR1）; 然后通过加入第二种酸或酸的混合物（G1b），通过进一步酸化原始黑液来沉淀木质素的第二沉淀相（PR2）。 实施第一阶段以降低pH值，同时避免任何更大量的沉淀，即小于2-5％，而实施第二阶段以获得更大部分的沉淀。 总原料黑液总木素含量的40-70％，沉淀后的残留黑液仍然是强碱性的。

公开(公告)号：US20140288284A1

公开(公告)日：2014-09-25

申请号：US14125616

申请日：2011-06-22

申请人： Peter Björklund ,  Martin Wimby ,  Henrik Wallmo

发明人： Peter Björklund ,  Martin Wimby ,  Henrik Wallmo

IPC分类号： C07G1/00

CPC分类号： C07G1/00 ,  C08H6/00 ,  C08H8/00 ,  D21C11/0007 ,  Y02P40/44

摘要： The method is for separation of lignin from original black liquor (BLIN) having the following phases in sequence; a first precipitation phase (PR1) for precipitation of lignin by a first acidification of the original black liquor by adding a first acid or mixture of acids (G1a); followed by a second precipitation phase (PR2) for precipitation of lignin by a further acidification of the original black liquor by adding a second acid or mixture of acids (G1b). The first phase is implemented to lower the pH while avoiding any larger amount of precipitation, i.e. less than 2-5%, while the second phase is implemented in order to obtain the larger part of the precipitation. In total is 40-70% of the total lignin content of the original black liquor precipitated while the residual black liquor after precipitation is still strongly alkaline.

摘要翻译： 该方法是将木质素与依次具有以下相的原黑液（BLIN）分离; 用于通过加入第一种酸或酸的混合物（G1a）首次酸化原始黑液来沉淀木质素的第一沉淀相（PR1）; 然后通过加入第二种酸或酸的混合物（G1b），通过进一步酸化原始黑液来沉淀木质素的第二沉淀相（PR2）。 实施第一阶段以降低pH值，同时避免任何更大量的沉淀，即小于2-5％，而实施第二阶段以获得更大部分的沉淀。 总原料黑液总木素含量的40-70％，沉淀后的残留黑液仍然是强碱性的。

公开(公告)号：US06706488B2

公开(公告)日：2004-03-16

申请号：US09915374

申请日：2001-07-27

申请人： Viveka Björklund ,  Bertil Björklund ,  Peter Björklund ,  Marius Nap ,  Frans C. S. Ramaekers ,  Bert Schutte

发明人： Viveka Björklund ,  Bertil Björklund ,  Peter Björklund ,  Marius Nap ,  Frans C. S. Ramaekers ,  Bert Schutte

IPC分类号： G01N3353

CPC分类号： C07K5/1021 ,  A61K38/00 ,  C07K14/4741 ,  C07K14/4747 ,  C07K16/18

摘要： Apoptosis-related antigenic compounds comprising an exposed antigenic site having the amino acid sequence SEQ ID NO: 1: Glu Asp Phe Asn Leu Gly Asp Ala Leu Asp 1               5                    10 or a functionally equivalent sequence comprising at least the sequence Ala Leu Asp are disclosed. Further, several applications and uses based on such compounds are included, such as use of the compounds in medicaments, nucleic acid sequences encoding the amino-acid sequence of such a peptide compound or protein fragment comprising the C-terminal amino acid sequence Ala Leu Asp, anti-sense nucleic acid sequence, vector comprising such a nucleic acid sequence, antibody or antigen-binding peptide recognizing such an antigenic compound and use thereof in a medicament, agents regulating the liberation of protein fragments comprising the amino-acid sequence SEQ ID NO: 1 or functionally equivalent sequences comprising the C-terminal amino acid sequence Ala Leu Asp, a method of determining the occurrence of cell apoptosis in a sample of biological material, especially in the diagnosis of degenerative diseases and cancer, or monitoring of the effect of therapy, a method of treating diseases with involvement of apoptosis, such as cancer and degenerative diseases, a method of creating cancer cells, and as carrier for prophylactic, therapeutic or diagnostic use.

公开(公告)号：US06296850B1

公开(公告)日：2001-10-02

申请号：US09162366

申请日：1998-09-29

申请人： Viveka Björklund ,  Bertil Björklund ,  Peter Björklund ,  Marius Nap ,  Frans C. S. Ramaekers ,  Bert Schutte

发明人： Viveka Björklund ,  Bertil Björklund ,  Peter Björklund ,  Marius Nap ,  Frans C. S. Ramaekers ,  Bert Schutte

IPC分类号： A61K3804

CPC分类号： C07K5/1021 ,  A61K38/00 ,  C07K14/4741 ,  C07K14/4747 ,  C07K16/18

摘要： Apoptosis-related antigenic compounds comprising an exposed antigenic site having the amino acid sequence SEQ ID NO: 1:   Glu Asp Phe Asn Leu Gly Asp Ala Leu Asp   1               5                    10 or a functionally equivalent sequence comprising at least the sequence Ala Leu Asp are disclosed. Further, several applications and uses based on such compounds are included, such as use of the compounds in medicaments, nucleic acid sequences encoding the amino-acid sequence of such a peptide compound or protein fragment comprising the C-terminal amino acid sequence Ala Leu Asp, anti-sense nucleic acid sequence, vector comprising such a nucleic acid sequence, antibody or antigen-binding peptide recognizing such an antigenic compound and use thereof in a medicament, agents regulating the liberation of protein fragments comprising the amino-acid sequence SEQ ID NO: 1 or functionally equivalent sequences comprising the C-terminal amino acid sequence Ala Leu Asp, a method of determining the occurrence of cell apoptosis in a sample of biological material, especially in the diagnosis of degenerative diseases and cancer, or monitoring of the effect of therapy, a method of treating diseases with involvement of apoptosis, such as cancer and degenerative diseases, a method of creating cancer cells, and as carrier for prophylactic, therapeutic or diagnostic use.

摘要翻译： 公开了包含具有氨基酸序列的暴露的抗原位点或至少包含序列Ala Leu Asp的功能等同序列的凋亡相关抗原化合物。 此外，包括基于这些化合物的几种应用和用途，例如在药物中使用化合物，编码这种肽化合物的氨基酸序列的核酸序列或包含C-末端氨基酸序列Ala Leu Asp的蛋白质片段 ，反义核酸序列，包含这种核酸序列的载体，识别这种抗原性化合物的抗体或抗原结合肽及其在药物中的用途，调节释放包含氨基酸序列SEQ ID NO ：1或包含C-末端氨基酸序列Ala Leu Asp的功能等同序列，确定生物材料样品中细胞凋亡发生的方法，特别是在退行性疾病和癌症的诊断中，或监测其作用 治疗，涉及凋亡的疾病如癌症和退行性疾病的方法，一种产生癌症的方法 细胞，以及作为预防，治疗或诊断用途的载体。