公开(公告)号：US20110178377A1

公开(公告)日：2011-07-21

申请号：US13120640

申请日：2009-09-23

申请人： Conor Heneghan ,  Conor Hanley ,  Niall Fox ,  Alberto Zaffaroni ,  Philip De Chazal

发明人： Conor Heneghan ,  Conor Hanley ,  Niall Fox ,  Alberto Zaffaroni ,  Philip De Chazal

IPC分类号： A61B5/00

CPC分类号： G06F19/3431 ,  A61B5/0002 ,  A61B5/4806 ,  A61B5/4815 ,  A61B5/72 ,  A61B5/7271 ,  A61B5/74 ,  G06F19/00 ,  G06F19/3418 ,  G06F19/36 ,  G16H10/20 ,  G16H50/20 ,  G16H50/30

摘要： An apparatus, system, and method for the measurement, aggregation and analysis of data collected using non-contact or minimally-contacting sensors provides quality of life parameters for individual subjects, particularly in the context of a controlled trial of interventions on human subjects (e.g., a clinical trial of a drug, or an evaluation of a consumer item such as a fragrance). In particular, non-contact or minimal-contact measurement of quality-of-life parameters such as sleep, stress, relaxation, drowsiness, temperature and emotional state of humans may be evaluated, together with automated sampling, storage, and transmission to a remote data analysis center. One component of the system is that the objective data is measured with as little disruption as possible to the normal behavior of the subject. The system can also support behavioral and pharmaceutical interventions aimed at improving quality of life.

摘要翻译： 用于使用非接触或最小接触传感器收集的数据的测量，聚集和分析的装置，系统和方法提供个体受试者的生活质量参数，特别是在对受试者的干预措施的对照试验（例如， ，药物的临床试验，或消费品如香料的评估）。 特别地，可以评估生活质量参数（例如睡眠，压力，放松，嗜睡，温度和人类的情绪状态）的非接触或最小接触测量，以及自动采样，存储和传输到远程 数据分析中心。 该系统的一个组成部分是测量客观数据，尽可能少地破坏主体的正常行为。 该系统还可以支持旨在提高生活质量的行为和药物干预措施。

公开(公告)号：US20090203972A1

公开(公告)日：2009-08-13

申请号：US12302704

申请日：2007-06-01

申请人： Conor Heneghan ,  Conor Hanley ,  Niall Fox ,  Philip De Chazal

发明人： Conor Heneghan ,  Conor Hanley ,  Niall Fox ,  Philip De Chazal

IPC分类号： A61B5/00

CPC分类号： A61B5/0205 ,  A61B5/0507 ,  A61B5/0816 ,  A61B5/0826 ,  A61B5/113 ,  A61B5/4818 ,  A61B5/7264

摘要： An apparatus, system, and method monitors the motion, breathing, heart rate and sleep state of subjects, e.g., humans, in a convenient, non-invasive/non-contact, and low-cost fashion. More particularly, the motion, breathing, and heart rate signals are obtained through processing applied to a raw signal obtained in a non-contact fashion, typically using a radio-frequency sensor. Periods of sleep disturbed respiration, or central apnea can be detected through analysis of the respiratory signal. The mean heart rate, and derived information, such as the presence of cardiac arrhythmias can be determined from the cardiac signal. Motion estimates can be used to recognize disturbed sleep and periodic limb movements. The sleep state may be determined by applying a classifier model to the resulting streams of respiratory, cardiac and motion data. A means for display of the sleep state, respiratory, cardiac, and movement status may also be provided.

摘要翻译： 装置，系统和方法以方便，非侵入/非接触和低成本的方式监测受试者（例如人）的运动，呼吸，心率和睡眠状态。 更具体地，通过应用于以非接触方式获得的原始信号的处理（通常使用射频传感器）获得运动，呼吸和心率信号。 睡眠期间呼吸紊乱或中枢性呼吸暂停可以通过分析呼吸信号进行检测。 可以从心脏信号中确定平均心率和派生信息，例如心律不齐的存在。 运动估计可用于识别受扰的睡眠和周期性肢体运动。 可以通过将分类器模型应用于所得到的呼吸，心脏和运动数据流来确定睡眠状态。 还可以提供用于显示睡眠状态，呼吸，心脏和运动状态的装置。

公开(公告)号：US07435221B1

公开(公告)日：2008-10-14

申请号：US11558819

申请日：2006-11-10

申请人： Rupinder Bharmi ,  Philip de Chazal ,  Gene A. Bornzin ,  Michael E. Benser

发明人： Rupinder Bharmi ,  Philip de Chazal ,  Gene A. Bornzin ,  Michael E. Benser

IPC分类号： A61B5/08 ,  A61B5/02 ,  A61B5/04

CPC分类号： A61B5/0452 ,  A61B5/0031 ,  A61B5/02405 ,  A61B5/0472 ,  A61B5/08 ,  A61B5/0803 ,  A61B5/0816 ,  A61B5/11 ,  A61B5/145 ,  A61B5/411 ,  A61B5/4818 ,  A61B5/7267 ,  A61N1/3601 ,  A61N1/365 ,  A61N1/37

摘要： Techniques are provided for detecting abnormal respiration within a patient based upon intracardiac electrogram (IEGM) signals or other electrical cardiac signals. Briefly, abnormal respiration is detected using a pattern recognition trained to discriminate normal and abnormal respiration based on morphological parameters and interval-based parameters extracted from the IEGM signals. In addition, techniques are described for distinguishing among different cardiac rhythm types within the patient while using one or more pattern classifiers or other pattern recognition devices.

摘要翻译： 提供了用于基于心内电描记图（IEGM）信号或其他电心脏信号来检测患者内异常呼吸的技术。 简而言之，使用根据从IEGM信号提取的形态参数和基于间隔的参数来鉴别正常和异常呼吸的训练的模式识别来检测异常呼吸。 此外，描述了用于在使用一个或多个模式分类器或其他模式识别装置的同时区分患者内的不同心律类型之类的技术。

公开(公告)号：US20060184056A1

公开(公告)日：2006-08-17

申请号：US11308429

申请日：2006-03-24

申请人： Philip de Chazal ,  Conor Heneghan ,  Elaine Sheridan

发明人： Philip de Chazal ,  Conor Heneghan ,  Elaine Sheridan

IPC分类号： A61B5/04

CPC分类号： A61B5/4818 ,  A61B5/04325 ,  A61B5/0456 ,  A61B5/7203 ,  A61B5/7207 ,  A61B5/7264 ,  A61B5/7267 ,  G06F19/00 ,  G16H50/20

摘要： An apparatus for diagnosing sleep apnea only uses an electrocardiogram signal and a computer processor and associated computer code that are configured to analyze the electrocardiogram signal and classify each time period of the electrocardiogram signal as either apneic or normal. A diagnostic measure of sleep apnea for the human patient is provided based on classification results obtained by combining a results for various electrocardiogram signal time periods. A computer-readable medium has computer code that causes the computer to analyze an electrocardiogram signal relating to the human patient and classify each time period in a set of time periods as either apneic or normal. A diagnostic measure of sleep apnea is provided based on classification results obtained by combining a plurality of results from the set of time periods using either time or frequency domain processing, or both.

摘要翻译： 用于诊断睡眠呼吸暂停的装置仅使用心电图信号和计算机处理器以及相关联的计算机代码，其被配置为分析心电图信号并将心电图信号的每个时间段分类为呼吸暂停或正常。 基于通过组合各种心电图信号时间段的结果而获得的分类结果，提供了针对人类患者的睡眠呼吸暂停的诊断测量。 计算机可读介质具有计算机代码，该计算机代码使得计算机分析与人类患者有关的心电图信号，并且在一组时间段内将呼吸暂停或正常的每个时间段分类。 基于通过使用时间或频域处理组合来自所述一组时间段的多个结果或两者来获得的分类结果来提供睡眠呼吸暂停的诊断测量。

公开(公告)号：US07025729B2

公开(公告)日：2006-04-11

申请号：US09952688

申请日：2001-09-14

申请人： Philip de Chazal ,  Conor Heneghan ,  Elaine Sheridan

发明人： Philip de Chazal ,  Conor Heneghan ,  Elaine Sheridan

IPC分类号： A61B5/0402

CPC分类号： A61B5/4818 ,  A61B5/04325 ,  A61B5/0456 ,  A61B5/7203 ,  A61B5/7207 ,  A61B5/7264 ,  A61B5/7267 ,  G06F19/00 ,  G16H50/20

摘要： There is provided a method of determining a diagnostic measure of sleep apnea including the following steps: acquiring an electrocardiogram signal, calculating a set of RR intervals and electrocardiogram-derived respiratory signal from said electrocardiogram, and hence calculating a set of spectral and time-domain measurements over time periods including power spectral density, mean, and standard deviation. These measurements are processed by a classifier model which has been trained on a pre-existing data base of electrocardiogram signals to provide a probability of a specific time period containing apneic episodes or otherwise. These probabilities can be combined to form an overall diagnostic measure. The system also provides a system and apparatus for providing a diagnostic measure of sleep apnea.