RON Binding Constructs and Methods of Use Thereof
    15.
    发明申请
    RON Binding Constructs and Methods of Use Thereof 审中-公开
    RON绑定构造及其使用方法

    公开(公告)号:US20130089554A1

    公开(公告)日:2013-04-11

    申请号:US13519675

    申请日:2010-12-29

    Abstract: This disclosure provides immunoglobulin binding molecules that specifically bind to human macrophage stimulating receptor (MST1 R, also referred to herein as recepteur d'origine Nantaise or RON), including antibodies and monospecific and multispecific single chain binding proteins having one or more other domains, such as one or more antibody constant region domains. Also provided are therapeutic applications of such binding proteins, such as for the treatment of cancer and inflammatory disorders.

    Abstract translation: 本公开提供了特异性结合人巨噬细胞刺激受体(MST1R,本文也称为接受者Nantaise或RON)的免疫球蛋白结合分子,包括具有一个或多个其它结构域的抗体和单特异性和多特异性单链结合蛋白,例如 作为一个或多个抗体恒定区结构域。 还提供了这种结合蛋白的治疗应用,例如用于治疗癌症和炎性疾病。

    Method of Monitoring a Gas Leakage Incident
    19.
    发明申请
    Method of Monitoring a Gas Leakage Incident 审中-公开
    监测气体泄漏事件的方法

    公开(公告)号:US20130201025A1

    公开(公告)日:2013-08-08

    申请号:US13367794

    申请日:2012-02-07

    CPC classification number: H04N7/181 H04N7/185

    Abstract: A system for monitoring a gas leakage incident in an industrial facility comprises a local area network, and a plurality of closed-circuit television cameras operatively connected to the local area network. The closed-circuit television cameras are positioned to provide video images of plural areas in a facility, with a central station operatively connected to the network for receiving video images from the television cameras. As plurality of gas detectors positioned in plural areas of the facility are operatively connected to the local area network, with each gas detector being operable to provide a signal which indicates occurrence of a gas leakage incident. Real-time monitoring of one or more gas-leakage incidents facilitates efficient evacuation of operating personnel, with the system preferably configured to automatically direct one or more of the closed-circuit television cameras to the area from which a gas leakage signal originates.

    Abstract translation: 用于监测工业设施中的气体泄漏事件的系统包括局域网和可操作地连接到局域网的多个闭路电视摄像机。 闭路电视摄像机被定位成在设施中提供多个区域的视频图像,中央站可操作地连接到网络,用于从电视摄像机接收视频图像。 由于定位在设施的多个区域中的多个气体检测器可操作地连接到局域网,每个气体检测器可操作以提供指示发生气体泄漏事件的信号。 对一个或多个气体泄漏事故的实时监测有助于操作人员的有效撤离,其中该系统优选地被配置成将一个或多个闭路电视摄像机自动地引导到气体泄漏信号源自的区域。

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