公开(公告)号：US08057595B2

公开(公告)日：2011-11-15

申请号：US12611716

申请日：2009-11-03

Applicant: Bryan Monro Armitage ,  Ira Ison ,  Mark Fulmer ,  Sean Kerr ,  Michael Lehmicke ,  Patrick Leamy ,  William Schiffer

Inventor： Bryan Monro Armitage ,  Ira Ison ,  Mark Fulmer ,  Sean Kerr ,  Michael Lehmicke ,  Patrick Leamy ,  William Schiffer

IPC: C04B12/02 ,  C04B28/14 ,  C09K3/00

CPC classification number: A61K31/74 ,  A61K33/06 ,  A61K33/42 ,  A61L24/001 ,  A61L24/0063 ,  A61L24/0084 ,  A61L27/425 ,  A61L27/46 ,  A61L27/50 ,  A61K2300/00

Abstract: The present invention relates in general to implantable compositions, and method for preparing same, containing a calcium salt-containing component, optionally demineralized bone, a plurality of discrete fibers, optionally a flow additive, and optionally continuous reinforcing fibers or an array of organized fibers in the form of mesh. Advantageously, the discrete fibers have a specific aspect ratio (length/diameter) from about 50:1 to about 1000:1. The addition of a small amount of discrete fibers and/or the continuous reinforcing fibers or fiber mesh can cause drastic increases in certain mechanical properties including flexural strength, flexural toughness, and/or screw pullout strength.

Abstract translation: 本发明一般涉及可植入组合物及其制备方法，其含有钙盐组分，任选的软化骨，多个离散纤维，任选的流动添加剂，以及可选地连续的增强纤维或有组织纤维阵列 以网格的形式。 有利地，离散纤维具有约50:1至约1000:1的特定纵横比（长度/直径）。 添加少量离散纤维和/或连续增强纤维或纤维网可导致某些机械性能的急剧增加，包括弯曲强度，弯曲韧性和/或螺纹拔出强度。

公开(公告)号：US07494950B2

公开(公告)日：2009-02-24

申请号：US10936188

申请日：2004-09-07

Applicant: Bryan Monro Armitage ,  Ira Ison ,  Mark Fulmer ,  Sean Kerr ,  Michael Lehmicke ,  Patrick Leamy ,  William Schiffer

Inventor： Bryan Monro Armitage ,  Ira Ison ,  Mark Fulmer ,  Sean Kerr ,  Michael Lehmicke ,  Patrick Leamy ,  William Schiffer

IPC: A61F2/28

CPC classification number: A61K31/74 ,  A61K33/06 ,  A61K33/42 ,  A61L24/001 ,  A61L24/0063 ,  A61L24/0084 ,  A61L27/425 ,  A61L27/46 ,  A61L27/50 ,  A61K2300/00

Abstract: The present invention relates in general to implantable compositions, and method for preparing same, containing a calcium salt-containing component, optionally demineralized bone, a plurality of discrete fibers, optionally a flow additive, and optionally continuous reinforcing fibers or an array of organized fibers in the form of mesh. Advantageously, the discrete fibers have a specific aspect ratio (length/diameter) from about 50:1 to about 1000:1. The addition of a small amount of discrete fibers and/or the continuous reinforcing fibers or fiber mesh can cause drastic increases in certain mechanical properties including flexural strength, flexural toughness, and/or screw pullout strength.

Abstract translation: 本发明一般涉及可植入组合物及其制备方法，其含有钙盐组分，任选的软化骨，多个离散纤维，任选的流动添加剂，以及可选地连续的增强纤维或有组织纤维阵列 以网格的形式。 有利地，离散纤维具有约50:1至约1000:1的特定纵横比（长度/直径）。 添加少量离散纤维和/或连续增强纤维或纤维网可导致某些机械性能的急剧增加，包括弯曲强度，弯曲韧性和/或螺纹拔出强度。

公开(公告)号：US20140274649A1

公开(公告)日：2014-09-18

申请号：US13826332

申请日：2013-03-14

Applicant: Sean Kerr ,  Jay Smith ,  Meredith Hans Moore

Inventor： Sean Kerr ,  Jay Smith ,  Meredith Hans Moore

IPC: A61M1/36 ,  B04B7/12

CPC classification number: A61M1/3693 ,  B01L3/5021 ,  B01L2300/0858 ,  B01L2400/0409 ,  B04B5/04 ,  B04B7/08 ,  B04B11/04 ,  G01N33/491

Abstract: Instrumentation is provided for the separation of a multiple component sample, such as BMA containing lysed red blood cells and a lysing agent, into a desired component, for example a cell pellet containing stem cells, and a remaining component. The application discloses a device that includes a separator configured to separate the desired portion from the remaining portion, a collector that is supported by the separator and configured to collect the desired component of the multiple component sample after the desired component has been separated from the remaining component by the separator, and a housing that at least partially encloses and supports the separator and the collector.

Abstract translation: 提供了用于将多组分样品（例如含有裂解的红细胞和裂解剂的BMA）分离成所需组分（例如含有干细胞的细胞沉淀）和剩余组分的仪器。 本申请公开了一种装置，其包括分离器，其被配置为将所需部分与剩余部分分离;收集器，其由分离器支撑并且构造成在所需部件与剩余部分分离之后收集多组分样品的期望成分 分离器，以及至少部分地包围并支撑分离器和收集器的壳体。

公开(公告)号：US08221782B2

公开(公告)日：2012-07-17

申请号：US13208837

申请日：2011-08-12

Applicant: Sean Kerr ,  James W. Dwyer

Inventor： Sean Kerr ,  James W. Dwyer

IPC: A61K33/42 ,  A61F2/00

CPC classification number: A61L27/50 ,  A61F2/28 ,  A61F2/30767 ,  A61F2002/2817 ,  A61F2002/30062 ,  A61F2002/30064 ,  A61F2002/30113 ,  A61F2002/30153 ,  A61F2002/30293 ,  A61F2002/30677 ,  A61F2002/30769 ,  A61F2002/30785 ,  A61F2002/30971 ,  A61F2210/0004 ,  A61F2230/0006 ,  A61F2230/0019 ,  A61F2230/0091 ,  A61F2310/00293 ,  A61F2310/00796 ,  A61L24/0089 ,  A61L27/46 ,  A61L2430/02

Abstract: The present invention relates in general to implantable flexible bone composites, and method for preparing the same. The flexible bone composite includes at least one polymeric layer and at least one calcium-containing layer. The polymeric layer can be a polymeric layer including a synthetic polymer. The calcium-containing layer can include a calcium compound such as β-Ca3(PO4)2. The flexible bone composites of the invention are useful as bone void fillers and have improved handling characteristics.

Abstract translation: 本发明一般涉及可植入的柔性骨组合物及其制备方法。 柔性骨复合材料包括至少一个聚合物层和至少一个含钙层。 聚合物层可以是包含合成聚合物的聚合物层。 含钙层可以包括钙化合物，例如-Ca 3（PO 4）2。 本发明的柔性骨复合材料可用作骨隙填料并且具有改进的处理特性。

公开(公告)号：US08197491B2

公开(公告)日：2012-06-12

申请号：US11959675

申请日：2007-12-19

Applicant: Sean Kerr ,  Edward August Kurek, III ,  Junior Julien

Inventor： Sean Kerr ,  Edward August Kurek, III ,  Junior Julien

IPC: A61B17/58 ,  A61B17/60 ,  A61F2/00

CPC classification number: A61B17/809 ,  A61B17/68 ,  A61B17/80 ,  A61B17/8802 ,  A61B17/8822 ,  A61B17/8836 ,  A61B2017/00004

Abstract: Methods and devices are shown for forming polymer fasteners into bone by expelling the polymer from a cannula. Devices and methods shown allow a user to form multiple fasteners of various sizes without re-loading a device. Devices and methods shown further provide temperature profiles during fastener formation that reduce or eliminate thermal necrosis. Devices and methods shown further provide fasteners with increased strength.

Abstract translation: 示出了通过从套管排出聚合物来形成聚合物紧固件到骨头中的方法和装置。 显示的设备和方法允许用户在不重新装载设备的情况下形成各种尺寸的多个紧固件。 显示的装置和方法进一步提供紧固件形成期间的温度曲线，其减少或消除热坏死。 所示的装置和方法进一步提供了具有增加的强度的紧固件。

公开(公告)号：US20120116247A1

公开(公告)日：2012-05-10

申请号：US13253461

申请日：2011-10-05

Applicant: Kortney Wawrzyniak ,  Peter Kurzyna ,  Michael Lehmicke ,  Sean Kerr ,  John Maurice Marthaler ,  Steven Paul Parmelee

Inventor： Kortney Wawrzyniak ,  Peter Kurzyna ,  Michael Lehmicke ,  Sean Kerr ,  John Maurice Marthaler ,  Steven Paul Parmelee

IPC: A61B10/02

CPC classification number: A61B10/025 ,  A61B2010/0258

Abstract: A bone marrow harvesting device includes a flexible bone marrow harvesting needle that can bend during operation to prevent the needle tip from piercing the inner cortical wall of the target bone. The needle defines an aspiration channel that defines an intake end that is recessed to reduce the instances that the aspiration channel will be fouled by bone particles or other debris within the cancellous portion.

Abstract translation: 骨髓采集装置包括柔性骨髓采集针，其可在操作期间弯曲以防止针尖刺穿目标骨的内皮质壁。 针限定了吸入通道，其限定了凹入的进气端，以减少抽吸通道将被松质骨部分内的骨颗粒或其他碎屑污染的情况。

公开(公告)号：US20100048763A1

公开(公告)日：2010-02-25

申请号：US12611716

申请日：2009-11-03

Applicant: Bryan Monro Armitage ,  Ira Ison ,  Mark Fulmer ,  Sean Kerr ,  Michael Lehmicke ,  Patrick Leamy ,  William Schiffer

Inventor： Bryan Monro Armitage ,  Ira Ison ,  Mark Fulmer ,  Sean Kerr ,  Michael Lehmicke ,  Patrick Leamy ,  William Schiffer

IPC: A61F2/00

CPC classification number: A61K31/74 ,  A61K33/06 ,  A61K33/42 ,  A61L24/001 ,  A61L24/0063 ,  A61L24/0084 ,  A61L27/425 ,  A61L27/46 ,  A61L27/50 ,  A61K2300/00

Abstract: The present invention relates in general to implantable compositions, and method for preparing same, containing a calcium salt-containing component, optionally demineralized bone, a plurality of discrete fibers, optionally a flow additive, and optionally continuous reinforcing fibers or an array of organized fibers in the form of mesh. Advantageously, the discrete fibers have a specific aspect ratio (length/diameter) from about 50:1 to about 1000:1. The addition of a small amount of discrete fibers and/or the continuous reinforcing fibers or fiber mesh can cause drastic increases in certain mechanical properties including flexural strength, flexural toughness, and/or screw pullout strength.

Abstract translation: 本发明一般涉及可植入组合物及其制备方法，其含有钙盐组分，任选的软化骨，多个离散纤维，任选的流动添加剂，以及可选地连续的增强纤维或有组织纤维阵列 以网格的形式。 有利地，离散纤维具有约50:1至约1000:1的特定纵横比（长度/直径）。 添加少量离散纤维和/或连续增强纤维或纤维网可导致某些机械性能的急剧增加，包括弯曲强度，弯曲韧性和/或螺纹拔出强度。

公开(公告)号：US20090198237A1

公开(公告)日：2009-08-06

申请号：US12388676

申请日：2009-02-19

Applicant: David Downey ,  Christoph Roth ,  Glen Pierson ,  Sean Kerr ,  Ali Recber

Inventor： David Downey ,  Christoph Roth ,  Glen Pierson ,  Sean Kerr ,  Ali Recber

IPC: A61B17/56

CPC classification number: A61B17/7098 ,  A61B17/1615 ,  A61B17/1721 ,  A61B17/1742 ,  A61B17/686 ,  A61B17/744 ,  A61B17/8635 ,  A61L31/127 ,  A61L2430/02 ,  C08L67/04

Abstract: The present invention is directed to an improved nail and an associated method for implanting the nail into a patient's bone. The nail preferably includes a proximal end, a distal end, a plurality of spiral blades (e.g., vanes) and a cannulated bore extending from the proximal end to the distal end so that in use an injectable material such as, for example PCL material, can be injected into the patient's bone through the cannulated bore formed in the nail. The nail also preferably includes a cutout portion at the distal end thereof in order to direct the outflow of injectable material through the cannulated bore. The cutout portion preferably is configured to facilitate the injectable material outflowing past the distal end of the nail and superiorly of the nail when the nail is properly implanted and positioned in situ.

Abstract translation: 本发明涉及一种用于将钉植入患者骨骼中的改进的钉子和相关联的方法。 钉子优选地包括近端，远端，多个螺旋叶片（例如，叶片）和从近端延伸到远端的插管孔，使得在使用中可注射材料，例如PCL材料， 可以通过形成在钉子中的插管孔注入患者骨骼。 指甲还优选地包括在其远端处的切口部分，以便引导可注射材料通过插管孔的流出。 切口部分优选地构造成当钉被适当地植入并定位在原位时，便于可注射材料流出超过钉的远端并且钉在上方。

公开(公告)号：US20080013888A1

公开(公告)日：2008-01-17

申请号：US11479254

申请日：2006-06-30

Applicant: Brandon Barnes ,  Bradley Billman ,  Sean Kerr ,  Joshua Raker ,  Charles Yow

Inventor： Brandon Barnes ,  Bradley Billman ,  Sean Kerr ,  Joshua Raker ,  Charles Yow

IPC: G02B6/36

CPC classification number: G02B6/4471 ,  G02B6/3801 ,  G02B6/3846 ,  G02B6/3887

Abstract: The present invention addresses the need for a stress relieving device and protective jacket for exposed fiber within a field-installed optical network enclosure, such as a network interface device. The present invention incorporates a furcation tube coupled with a furcation body. The coupling may be accomplished by a direct connection or with use of an external or internal transition body. The present invention enables a field-installer to transition an optical fiber cable from the field into a furcation tube thereby providing a means for attaching an optical connector, such as a mechanical splice connector, onto the optical fiber and furcation tube.

Abstract translation: 本发明解决了在诸如网络接口设备的现场安装的光网络外壳中需要用于外露光纤的应力释放装置和保护套。 本发明包括与分叉体结合的分叉管。 联接可以通过直接连接或使用外部或内部过渡体实现。 本发明使现场安装者能够将光纤电缆从现场转变成分叉管，从而提供用于将诸如机械接头连接器的光学连接器附接到光纤和分叉管上的装置。

公开(公告)号：US20050209629A1

公开(公告)日：2005-09-22

申请号：US11067438

申请日：2005-02-25

Applicant: Sean Kerr ,  Stuart Weikel ,  James Dwyer

Inventor： Sean Kerr ,  Stuart Weikel ,  James Dwyer

IPC: A61B17/56 ,  A61B17/00 ,  A61B17/02 ,  A61B17/72 ,  A61B17/88 ,  A61F2/00 ,  A61F2/02 ,  A61F2/30 ,  A61F2/44 ,  A61F2/958 ,  A61M25/00 ,  A61M29/00

CPC classification number: A61B17/025 ,  A61B17/7097 ,  A61B17/7225 ,  A61B17/7258 ,  A61B17/7275 ,  A61B2017/00004 ,  A61B2017/00557 ,  A61B2017/0084 ,  A61B2017/00858 ,  A61B2017/00867 ,  A61F2/0077 ,  A61F2/30767 ,  A61F2/30771 ,  A61F2/30965 ,  A61F2/4455 ,  A61F2002/0081 ,  A61F2002/30062 ,  A61F2002/3008 ,  A61F2002/30561 ,  A61F2002/30677 ,  A61F2002/444 ,  A61F2210/0004 ,  A61F2250/0098 ,  A61F2310/00389 ,  A61M25/1002

Abstract: The present invention is directed to a resorbable containment device for use in treating voids in bone and restoring the anatomy of diseased or fractured bone. The resorbable containment device may be a balloon of varied size or shape to conform to the bone to be treated and may be deployed in any type of bone where collapsed fractures of cortical bone may be treated by restoring the bone from its inner surface. The containment device may be formed from a pluronic based polymer and may degrade in-vivo within a period of weeks after implantation into bone. The balloon may have multiple layers to provide desired surface characteristics, resistance to puncture and tearing, or other beneficial properties, as appropriate for the particular application of the device.

Abstract translation: 本发明涉及一种可再吸收的容纳装置，用于治疗骨中的空隙并恢复患病或骨折的解剖结构。 可再吸收的容纳装置可以是不同尺寸或形状的气囊，以符合待治疗的骨骼，并且可以部署在任何类型的骨中，其中皮质骨的塌陷骨折可以通过从其内表面恢复骨来治疗。 容纳装置可以由基于聚醚的聚合物形成，并且可以在植入骨之后的几周内在体内降解。 气囊可以具有多个层以提供期望的表面特征，抗穿刺和撕裂，或其它有益的性质，适合于该装置的具体应用。