Abstract:
A method for controlling directly and in real time positioning of a biological element on a zone of a support, in which the biological element is labeled with a tracer that emits a light radiation and the zone of the support is located in a layer of a material capable of trapping the light radiation. The biological element is positioned on the zone of the support. The intensity of the light radiation trapped in the layer is measured. The positioning of the biological element is determined by comparing the intensity thus measured with at least one reference value. The above operations can be carried out successively or simultaneously. A device can apply the method to the positioning of one or more biological elements on one or more zones of a support.
Abstract:
A 3D imaging device is comprised of a photodetector matrix, a layer of material fixed on a face of the photodetector matrix, the layer of material being capable of absorbing or reflecting light, an opening being formed in said layer of material at each photodetector, a layer of insulating material fixed on said layer of material capable of reflecting or absorbing light, the layer of insulating material having a face surrounding, in the body thereof, a set of G waveguides, each waveguide of the set of waveguides being positioned vertically in relation to said face, opposite an opening, the heights of the different waveguides, considered in relation to the face of the layer of insulating material, defining N distinct levels, N being a whole number greater than or equal to 2.
Abstract:
A device for trapping particles contained in a liquid (L) placed in a tank, characterized in that it comprises a substrate that is transparent at a working wavelength, a thin layer of material with non-linear optical properties that are reversible at the working wavelength and which is fixed to a first face of the transparent substrate to form all or part of at least one wall of the tank, a device for forming an optical trap which comprises a laser source which emits a laser beam and means for forming a waist of the laser beam, the laser beam being incident upon that face of the transparent substrate that lies on the opposite side to the first face and the waist of the laser beam being formed in the thin layer, an evanescent electromagnetic field forming at the surface of the thin layer.
Abstract:
The invention relates to a sample support designed to support a sample which is to be detected and/or analyzed by a photothermal detection method using an irradiation pump beam irradiating the sample and a detection and/or analysis probe beam. It comprises a substrate supporting a stack of thin dielectric layers forming a Bragg mirror on which the sample will be supported, the stack of thin dielectric layers being used to reflect the pump beam that reaches it.The invention also relates to a device for detection and/or analysis of a sample by a photothermal method, the said device comprising a sample support according to the invention, a means of lighting the sample supported by the said support and supplying a pump beam, a means of detection and/or measurement of the absorption or reflection of the pump beam by the sample when it is illuminated by the said illumination means.Finally, the invention relates to a particular application of the said device.